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Introduction About NUTEC PLUS TABLET
NUTEC PLUS TABLET is a combination of Metoclopramide and Paracetamol which belong to the groups of medicines called Antiemetics and Analgesics respectively. It is used to manage pain, nausea and vomiting associated with migraine attacks.
Migraine is a neurological condition that is thought to be caused by the widening of certain blood vessels in the brain, causing an intense, throbbing, recurrent headache on one side of the head, usually around the temple region, but sometimes it can start in the forehead, around the eye or at the back of the head. There are many symptoms that may accompany migraines; nausea (feeling sick) is one of the most common.
Avoid consuming alcohol while taking NUTEC PLUS TABLET because it might make you feel dizzy or sleepy. NUTEC PLUS TABLET is not recommended for use in patients with stomach and/or digestive tract bleeding, intestinal blockage, recent stomach and/or intestine surgery, phaeochromocytoma (a rare tumour of the adrenal gland) or epilepsy.
NUTEC PLUS TABLET should only be used in pregnant women if necessary and should be avoided in breastfeeding women. Before using NUTEC PLUS TABLET, inform your doctor if you have any history of liver or kidney problems, glutathione deficiency, hemolytic anaemia, dehydration, malnutrition for a long period, breast cancer or Parkinson's disease.
NUTEC PLUS TABLET is generally not recommended for use in children under the age of one year.NUTEC PLUS TABLET should also be used cautiously with elderly patients. The most common side effects of NUTEC PLUS TABLET are headache, dizziness, indigestion, drowsiness, tiredness, restlessness and diarrhoea. If any of these symptoms worsen, consult your doctor.
Uses Of NUTEC PLUS TABLET
- Manage pain, nausea and vomiting associated with migraine attack
How NUTEC PLUS TABLET Works
NUTEC PLUS TABLET provides relief from migraine attacks where Metoclopramide blocks the action of a chemical substance produced in the brain that initiates vomiting along with increasing muscle contractions in the stomach and intestine and Paracetamol works by stopping the release of certain chemical messengers that cause pain and fever. This collective action is therefore useful in managing nausea, vomiting and headaches associated with migraine effectively.
How to use NUTEC PLUS TABLET
Always use NUTEC PLUS TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. The correct dose and duration of therapy will be decided by your doctor depending on your age, weight and disease condition. Do not take more than the recommended dosage, as it may lead to side effects.
Side Effects Of NUTEC PLUS TABLET
Common
- drowsiness
- depressed mood
- muscle spasms of your face and jaw, speech problems, unnatural tongue and rolling eyes, unnatural positioning of your head, shoulders and spine
- difficulty with movement, tremors or restlessness
- diarrhoea
- weakness
Uncommon
- increased milk production
- irregular or absent monthly periods
- hallucination
- decreased consciousness level
Rare
- feeling irritable and confused
- constipation
- feeling sick (nausea)
- dry mouth
- difficulty sleeping
Stop taking NUTEC PLUS TABLET and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction signs (skin rash, itching, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, wheezing or shortness of breath)
- signs of the neuroleptic malignant syndrome (sudden increase in body temperature, extremely high blood pressure, stiff muscles and severe convulsions)
- methaemoglobinaemia (bluish colouration of skin)
- signs of tardive dyskinesia (sudden mood changes, uncontrolled and repeated movements of the arms, legs, eyes, mouth, tongue, face and jaw)
- bruising more easily, sore throat or other signs of infection (these may be signs of a blood disorder)
- severe pain in the abdomen and back, with fever (high temperature), loss of appetite, nausea and vomiting (these may be signs of pancreas inflammation)
How To Manage Side Effects
Dizziness:
Sit down or lie down slowly when you are feeling dizzy. Take some time to rest and drink plenty of water. Avoid coffee and other carbonated drinks. If the symptom does not improve, contact your doctor.
Diarrhoea:
Drink lots of fluids, such as water or fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Warning & Precautions
Pregnancy
NUTEC PLUS TABLET is recommended for use in pregnant women or women planning to become pregnant only if it is considered necessary. Therefore, consult your doctor for advice.
Breastfeeding
NUTEC PLUS TABLET is not recommended for use in breastfeeding women as it may pass into breast milk and can affect the breastfeeding infant. Consult your doctor for advice.
Driving and Using Machines
Do not drive or operate any machines if you feel dizzy, drowsy or tired after taking NUTEC PLUS TABLET.
Alcohol
Avoid consumption of alcohol while taking NUTEC PLUS TABLET because it might make you feel dizzy or sleepy.
Kidney
NUTEC PLUS TABLET should be used with caution in patients with kidney problems. Consult your doctor for advice.
Liver
NUTEC PLUS TABLET should be used with caution in patients having impaired liver function and liver diseases such as Gilbert’s syndrome and glucose 6 phosphate dehydrogenase deficiency. Consult your doctor for advice.
Allergy
Do not take NUTEC PLUS TABLET if you are allergic to paracetamol or metoclopramide.
Heart Disease
NUTEC PLUS TABLET should be used with caution in patients with a history of abnormal heartbeats (QT interval prolongation) or any other heart problems.
Others
NUTEC PLUS TABLET is not recommended for use if you:
- have bleeding from the stomach and/or digestive tract
- have a blockage in the intestine
- have recent surgery on the stomach and/or intestine
- have phaeochromocytoma, a rare tumour of the adrenal gland
- have epilepsy
Before taking NUTEC PLUS TABLET inform your doctor if you:
- have glutathione deficiency
- have haemolytic anaemia
- have dehydration
- have malnutrition for a long period
- are weighed less than 50 kg
- have breast cancer
- have Parkinson's disease condition affecting muscle control
Use in Pediatrics:
NUTEC PLUS TABLET is not recommended for use in children less than 1 year of age. Consult your doctor for advice.
Use in Geriatrics:
NUTEC PLUS TABLET should be used with caution in elderly patients. Therefore, consult your doctor for advice.
Interactions
A. Drug-Drug interactions:
Before taking NUTEC PLUS TABLET, inform your doctor if you are taking any of the following medicine:
- warfarin and clorindione (medicines used to manage blood clots)
- phenobarbital, phenytoin, carbamazepine, topiramate (medicines used to manage epilepsy)
- other medicines that relieve pain (Ex. codeine and morphine)
- medicines used to manage travel sickness, hayfever and allergy (dicyclomine, atropine and fesoterodine)
- medicines used to manage mental health illness (Ex. fluoxetine, risperidone, aripiprazole and clozapine)
- levodopa (a medicine used in the management of Parkinson's disease)
- digoxin (a medicine used to manage heart failure)
Overdosage:
If you or anyone else accidentally take too much of NUTEC PLUS TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of an overdose might include dizziness, drowsiness, confusion, increased sweating, vomiting, stomach pain, convulsions or fits, uncontrolled muscle movements and yellowing of the skin.
Synopsis
| Drug | : | Metoclopramide, Paracetamol |
| Pharmacological Category | : | Dopamine antagonist, Analgesics |
| Therapeutic Indication | : | Nausea, vomiting and headache in migraine |
| Dosage Forms | : | Tablet, Suspension |
More Information
- Keep NUTEC PLUS TABLET out of reach from children
- Store at room temperature
FAQs About NUTEC PLUS TABLET
Q: Can I stop taking NUTEC PLUS TABLET once I feel better?
A: No, do not stop taking NUTEC PLUS TABLET just because you feel better. It is important that you complete the course of medicine prescribed for you by the doctor. If you stop taking NUTEC PLUS TABLET too soon, your symptoms may come back.
Q: Can NUTEC PLUS TABLET be used on children?
A: NUTEC PLUS TABLET is generally not recommended for use in children and adolescents below 18 years of age. Therefore, consult your doctor before taking NUTEC PLUS TABLET.
Q: Should I take NUTEC PLUS TABLET along with meals?
A: Yes, you can take NUTEC PLUS TABLET during meals or at any time between meals. Always take this medicine exactly as your doctor has instructed. If you have any doubts regarding it, please consult your doctor for advice.
Q: Can I consume alcohol while taking NUTEC PLUS TABLET?
A: No, you should not consume alcohol while taking NUTEC PLUS TABLET because it might make you feel more dizzy or sleepy. This medicine should also be used with caution in patients with alcohol dependence.
References
1. KD Tripathi. Non-Steroidal Anti-inflammatory drugs, Analgesics and Antipyretics; Gastrointestinal Drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page – 223,224,709.
2. Wadher, S. J., P. R. Pathankar, Manisha Puranik, R. O. Ganjiwale and P. G. Yeole. Simultaneous spectrophotometric estimation of paracetamol and metoclopramide hydrochloride in the solid dosage form. Indian Journal of Pharmaceutical Sciences. [Revised in June 2008] [Accessed on 9th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792518/
3. Salazar, Gabriel, Marta Fragoso, Luis Vergez, Piera Sergio and Denisse Cuello. Metoclopramide as an analgesic in severe migraine attacks: an open, single-blind, parallel control study. Recent Patents on CNS Drug Discovery (Discontinued). [Revised in May 2011] [Accessed on 9th June 2022] https://doi.org/10.2174/157488911795933947
4. Aspen Pharmacare Australia Pty Limited. Anagraine Tablets. [Revised in December 2021] [Accessed on 9th June 2022] https://www.nps.org.au/medicine-finder/anagraine-tablets
5. Sanofi-Aventis Ireland Limited. Health Products Regulatory Authority (HPRA). [Revised in December 2019] [Accessed on 9th June 2022]. https://www.hpra.ie/img/uploaded/swedocuments/Licence_PA0540-154-001_01122019121549.pdf
Useful Diagnostic Tests
- Complete blood count
- Liver function tests
- Fibrinogen level
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