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Introduction About NUROVITA G TABLET 10'S
NUROVITA G TABLET 10'S is a combination of Gabapentin and Methylcobalamin which belongs to the group of medicines called Anticonvulsants and Vitamin-B complex respectively. It is used to manage nerve pain (also known as neuropathic pain).
Take NUROVITA G TABLET 10'S as directed by your physician. It can be taken with or without meals. Before taking NUROVITA G TABLET 10'S inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have fits disorders, nerve problems, Vitamin B9/Vitamin B6 deficiency or a history of drug abuse as a precaution.
Do not take NUROVITA G TABLET 10'S without consulting your doctor if you are pregnant or breastfeeding. The most common side effects of taking NUROVITA G TABLET 10'S are increased infections, confusion, anxiety, hostility, emotional liability, abnormal thinking, sleepiness, dizziness, nausea, vomiting and tiredness. Consult your doctor if any of these side effects trouble you.
You must also inform your doctor immediately if you experience severe depressive symptoms along with suicidal thoughts or thoughts of harming or killing oneself after taking NUROVITA G TABLET 10'S as a precaution.
Uses Of NUROVITA G TABLET 10'S
- Manage nerve pain
How NUROVITA G TABLET 10'S Works
NUROVITA G TABLET 10'S contains two medicines namely gabapentin and methylcobalamin. Gabapentin reduces pain sensation by interfering with the pain signals travelling between the damaged nerves and the brain.
Methylcobalamin is a vitamin. It repairs and rejuvenates the damaged nerve cells. It improves the production of a substance called myelin which forms a protective covering around the nerve fibres. This protects the nerve cells from getting damaged further. Collectively, this medicine effectively reduces nerve pain and protects the nerve cells from further damage.
How to use NUROVITA G TABLET 10'S
Take NUROVITA G TABLET 10'S as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. NUROVITA G TABLET 10'S can be taken with or without food.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking NUROVITA G TABLET 10'S abruptly without consulting your doctor.
Side Effects Of NUROVITA G TABLET 10'S
Common
- viral infections, fever, sore throat, cough
- dizziness, drowsiness, sleepiness or lack of sleep
- tiredness, weakness
- lack of coordination or balance, muscle pain, joint pain
- nausea, vomiting
- hostility (a strong sense of belief)
- confusion, emotional liability
- increased appetite or lack of appetite
- anger, anxiety, nervousness, depression, mood changes
- abnormal thinking, slurred speech, loss of memory
- headache
- numbness of body parts
- blurred vision or double vision
- flushing, high blood pressure
- dry nose, dry mouth, inflamed gums
- stomach pain, diarrhea, indigestion, constipation, bloating
- weight gain
- impotence (problems in erections)
- swelling of face, hands or legs
Uncommon
- agitation
- racing heartbeat
- liver problems
- increase in blood sugar levels
Rare
- low blood glucose levels
Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects:
- muscle pain and/or weakness
- signs of inflammation in the pancreas (such as persistent stomach pain, nausea, vomiting)
- suicidal thoughts (thoughts of harming or killing themselves)
- signs of a severe allergic reaction (skin rash with blisters and peeling, swelling of the eye, throat or tongue which leads to difficulty in breathing)
- shortness of breath or shallow breaths
- severe skin reactions (such as skin rash, redness, itching and hair loss)
How To Manage Side Effects
Nausea and vomiting:
Try to take NUROVITA G TABLET 10'S with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. If you experience severe nausea or vomiting along with severe stomach pain, contact your doctor immediately.
Diarrhea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhea. Consult your doctor if the symptom worsens.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom worsens.
Weight gain:
Weight gain caused due to NUROVITA G TABLET 10'S is often dose dependent and it is predominantly seen among diabetic patients. Try to exercise more regularly and eat a healthy balanced diet as instructed by your doctor. Consult your doctor if the symptom worsens.
Warning & Precautions
Pregnancy
NUROVITA G TABLET 10'S is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it. Women of childbearing potential should use a suitable contraceptive method to avoid pregnancy while taking this medicine.
Breastfeeding
NUROVITA G TABLET 10'S is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any heavy tools or machines if you experience dizziness or sleepiness after taking NUROVITA G TABLET 10'S.
Alcohol
Avoid consumption of alcohol while taking this medicine, as it could make you feel sleepy.
Kidney
NUROVITA G TABLET 10'S should be used with caution in patients with kidney diseases (including dialysis). Therefore, consult your doctor before taking it.
Liver
NUROVITA G TABLET 10'S should be used with caution in patients with liver diseases. Therefore, consult your doctor before taking it.
Allergy
Do not take NUROVITA G TABLET 10'S if you are allergic to Gabapentin or to Methylcobalamin.
Lungs
NUROVITA G TABLET 10'S should be used with caution in patients with respiratory disorders. Therefore, consult your doctor before taking it.
Heart Disease
NUROVITA G TABLET 10'S should be used with caution in patients with hypertension (high blood pressure) or any other heart problems. Therefore, consult your doctor before taking it.
Others
Before taking NUROVITA G TABLET 10'S, inform your physician if you:
- suffer from different types of seizures (such as absence, tonic-clonic, myoclonic)
- have any other nerve problems
- have a history of misuse or substance abuse
- work on places which requires handling mercury or mercury components
- have folate deficiency
- are going for a urine test
- have Vitamin B6 deficiency
Use in Pediatrics:
NUROVITA G TABLET 10'S is not recommended for use in children aged below 6 years. You must consult your doctor before using this medicine in children aged above 6 years as a precaution.
Use in Geriatrics:
NUROVITA G TABLET 10'S should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it. Proper dose adjustments and careful monitoring are required in such patients.
Interactions
A. Drug-Drug Interactions:
Before taking NUROVITA G TABLET 10'S, inform your doctor if you are taking any of the following medicines such as:
- oral contraceptives (birth control pills) Ex. norethisterone and/or ethinyl estradiol
- nitrous oxide (an anesthetic)
- neuroleptic drugs (used to manage epilepsy) Ex. phenytoin, carbamazepine, valproic acid
- neomycin (used to manage bacterial infections)
- colchicine (used to manage gout)
- medicines used to manage depression (Ex. sertraline, isocarboxazid, phenelzine or tranylcypromine)
- medicines that can reduce anxiety and induce sleep (Ex. phenobarbital, clonazepam etc.)
- medicines used to manage psychiatric illness (such as chlorpromazine)
- opioids (used for pain relief) such as morphine
- antacids (used to neutralize stomach acid production) such as aluminium hydroxide, magnesium hydroxide
- tetracyclines (used to manage bacterial infections)
- medicines used to manage cancer (such as doxorubicin, cisplatin, carboplatin)
- para-amino salicylic acid (used to manage tuberculosis)
- medicines used to manage diabetes orally (such as metformin, phenformin)
- medicines used to manage stomach ulcers (such as ranitidine, cimetidine)
- potassium chloride (used to manage potassium deficiency)
- cholestyramine (a medicine used to control blood cholesterol levels)
B. Drug-Food interaction:
This medicine can be taken with or without food.
Overdosage:
If you or anyone else accidentally took much of this medicine, contact your doctor immediately or go to a hospital straight away. Symptoms of overdosage might include dizziness, drowsiness, tiredness, fainting, double vision, slurred speech and mild diarrhoea.
Synopsis
| Drug | : | Gabapentin, Methylcobalamin |
| Pharmacological Category | : | Cyclic GABA analogs, Vitamin B complex |
| Therapeutic Indication | : | Nerve Pain |
| Dosage Forms | : | Tablet, Capsule |
More Information
- Keep NUROVITA G TABLET 10'S out of reach of children
- Store NUROVITA G TABLET 10'S at room temperature
- Protect from light and moisture
FAQs About NUROVITA G TABLET 10'S
Q: How long will it take for NUROVITA G TABLET 10'S to start acting?
A: NUROVITA G TABLET 10'S may start to exert its analgesic effects from day 2 of administration. An initial benefit of pain relief can be seen in patients after 2-4 weeks of therapy. However, it may take few months to show effects in some individuals.
Q: How long will the effects of NUROVITA G TABLET 10'S last long?
A: The effects of NUROVITA G TABLET 10'S can last long between 12-24 hr. This time range may vary among individuals, depending upon the severity of the disease condition.
Q: Can NUROVITA G TABLET 10'S manage diabetic neuropathy?
A: Yes. NUROVITA G TABLET 10'S can be used to manage diabetic neuropathy. It provides symptomatic pain relief in patients who have nerve pain caused due to diabetes.
Q: What happens if I stop taking NUROVITA G TABLET 10'S?
A: Do not stop taking NUROVITA G TABLET 10'S unless your doctor tells you as it may lead to withdrawal symptoms such as difficulty in falling asleep, anxiety, nausea, pain and sweating. Therefore, continue to take NUROVITA G TABLET 10'S as long as instructed by your doctor to achieve better results.
Q: Can NUROVITA G TABLET 10'S reduce nerve damage?
A: Yes. NUROVITA G TABLET 10'S can reduce further nerve damage. It repairs and rejuvenates the damaged nerve fibres. It improves myelin production in the body which repairs and rebuilds the protective covering around the nerve fibres which manages it from further damage.
Q: Is taking NUROVITA G TABLET 10'S safe?
A: The safety of NUROVITA G TABLET 10'S varies with patient to patient. Your doctor will closely monitor your health condition while taking NUROVITA G TABLET 10'S to avoid the risk of side effects.
Q: Is NUROVITA G TABLET 10'S addictive?
A: Research has shown that NUROVITA G TABLET 10'S can cause drug abuse or dependence. Therefore, it is better to inform your doctor before taking this medicine, if you already have a previous history of substance abuse as a precaution.
Q: Can NUROVITA G TABLET 10'S cause weight gain? If so, how can I manage my weight?
A: NUROVITA G TABLET 10'S may increase your body weight. It increases your hunger (appetite) which makes you eat more and eventually leads to increase in body weight. Weight can be managed by doing regular exercise and by eating a healthy balanced diet. Avoid calorie-rich foods such as soft drinks, chips, cakes, biscuits and sweets. Research says that patients with diabetes tend to put on weight easily while taking NUROVITA G TABLET 10'S. Dose adjustments for antidiabetic medicines can help in such situations. If the symptom bothers you, consult your doctor for advice.
Q: Can NUROVITA G TABLET 10'S cause sleepiness or drowsiness?
A: Yes. NUROVITA G TABLET 10'S may cause sleepiness and drowsiness. Rest and relax while feeling sleepy. Avoid consumption of alcohol while taking NUROVITA G TABLET 10'S as it can make you feel drowsier. Do not drive or operate any tools or machines while you are feeling sleepy. Consult your doctor if the symptom bothers you.
Q: Will the use of NUROVITA G TABLET 10'S affect my sex life?
A: Yes. NUROVITA G TABLET 10'S can affect sexual life of both men and women. It decreases sexual desire in men and women and can cause difficulty in erection or delayed ejaculation in men. The exact mechanism behind these effects is not known. If you experience any such problems, contact your doctor immediately.
Q: Can I take NUROVITA G TABLET 10'S along with alcohol?
A: No. Avoid consumption of alcohol while taking NUROVITA G TABLET 10'S as it may make you feel drowsier. Moreover, NUROVITA G TABLET 10'S is not recommended for use in patients having alcohol abuse unless considered necessary. Therefore, consult your doctor before taking it.
Q: Can I take a higher dose of NUROVITA G TABLET 10'S to increase pain relieving effects?
A: No. Do not take a higher dose of NUROVITA G TABLET 10'S than recommended by your doctor. Taking a higher dose of NUROVITA G TABLET 10'S without consulting a doctor can increase the risk of toxicity and can lead to side effects. If the prescribed dose is not effective for you, consult your doctor for a suitable higher dose. Never consume a higher dose NUROVITA G TABLET 10'S without proper medical supervision.
Q: What to do if I forgot to take NUROVITA G TABLET 10'S?
A: Take NUROVITA G TABLET 10'S as soon as you remember until it’s time for the next one. If you missed a dose, skip the missed one and take the next dose at time normally you would take. Do not take a double dose to make up the missed one, as it may lead to overdosage. If you are not sure, consult your doctor. Your doctor may instruct you about the next steps.
Q: What are the precautions that I need to follow while taking NUROVITA G TABLET 10'S?
A: Before taking NUROVITA G TABLET 10'S, inform your doctor about your pre-existing disease conditions as precaution. NUROVITA G TABLET 10'S should not be used if you are planning to become pregnant without consulting your doctor. NUROVITA G TABLET 10'S can cause extreme sleepiness and dizziness and therefore avoid taking other medicines or alcohol that can make you feel drowsier ever more. It can also impair memory, attention and thinking ability in few individuals and so avoid travelling or driving on your own for a while. If case of any queries, consult your doctor for advice.
References
1. KD. Tripathi. Antiepileptic Drugs & Hematinics and Erythropoietin. Essentials of medical pharmacology. Seventh edition. 2013. Page – 419 & 608.
2. Ming Zhang, Wenjuan Han, Sanjue Hu and Hui Xu. Methylcobalamin: A Potential Vitamin of Pain Killer. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. December 2013. [Accessed on 11th January 2023]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888748/
3. Aisha Hasan, Muhammad Haroon Khilan, Aizaz Khan, Mohammad Haroon Hassan, Anab Rehan Taseer, Sajid Iqbal, Mahnoor Amir and Muhammad Ashraf Chaudhary. Comparison of Gabapentin Monotherapy vs. Combination Therapy of Methyl Cobalamin and Gabapentin in Treating Diabetic Neuropathic Pain. Journal of Biology and Today’s World. 2020. [Accessed on 11th January 2023]. https://www.iomcworld.org/articles/comparison-of-gabapentin-monotherapy-vs-combination-therapy-of-methyl-cobalamin-and-gabapentin-in-treating-diabetic-neuropathic-pa-55830.html
4. Milpharm Limited. Gabapentin Milpharm 100/300/400 mg capsules, hard. Electronic Medicines Compendium. [Revised in December 2022]. [Accessed on 11th January 2023]. https://www.medicines.org.uk/emc/files/pil.4121.pdf
5. Torrent Pharmaceuticals Ltd. Gabator M. [Revised in August 2022]. [Accessed on 11th January 2023]. https://www.torrentian.com/pisheet/Upload/PI_Sheet/3108.pdf
6. LaRenon Healthcare Pvt Ltd. Laregab-M. June 2005. [Accessed on 11th January 2023]. https://www.larenon.com/wp-content/uploads/2022/03/LAREGAB-M-LBL.pdf
7. Central Drugs Standard Control Organization. Methylcobalamin 1500 mcg + Gabapentin SR 600 mg film coated tablets (additional strength). November 2009. FDC of Gabapentin (300mg) + Methylcobalamin (500mcg) Tablet. May 2005. Gabapentin 100mg + methylcobalamin 500mcg tablets (Additional Strength). January 2008. [Accessed on 11th January 2023]. https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
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