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Key Composition
NP COM TABLET is a combination of Nimesulide and Paracetamol, which belongs to the group of medicines called Non-steroidal Anti-inflammatory drugs. NP COM TABLET is used to provide relief from inflammation and pain in conditions such as headache, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, and/or painful menses in affected individuals.
NP COM TABLET is not recommended for use in patients allergic to nimesulide, paracetamol, and/or other NSAIDS. It is also not recommended for use in patients with peptic ulcers, gastrointestinal bleeding, severe liver disease, and/or severe kidney disease.
Before taking NP COM TABLET, inform your doctor if you are alcohol dependent and/or have other kidney problems and/or heart problems such as heart failure.
NP COM TABLET is not recommended for use during pregnancy and in breastfeeding women. It is also not recommended for use in children (aged below 12 years). NP COM TABLET should be used with caution in elderly patients (aged above 65 years) after consulting the doctor.
The most common side effects of NP COM TABLET are dizziness, excess sleepiness, stomach upset, nausea, abdominal discomfort, diarrhea, and/or peripheral oedema (swelling in legs or arms). Consult your doctor if any of the symptoms worsen.
Uses Of NP COM TABLET
- Provides relief from inflammation and pain in conditions (such as headache, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, and/or painful menses) in affected individuals.
How NP COM TABLET Works
NP COM TABLET provides relief from pain and inflammation, where nimesulide and paracetamol act by blocking the action of prostaglandin (chemical messengers responsible for pain and inflammation), resulting in reduced inflammation and providing relief from pain in affected individuals.
How to use NP COM TABLET
Take NP COM TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects Of NP COM TABLET
Common
- Dizziness, excess sleepiness
- Stomach upset, nausea, abdominal discomfort, diarrhea
- Peripheral oedema (swelling in legs/arms)
- Signs of hypersensitivity reactions such as skin rash, red itchy welts, itching, and shortness of breath
Rare
Stop taking NP COM TABLET and contact your doctor immediately if you experience any of the following side effects:
- Signs of severe allergic reactions such as skin rash, itching, swelling of the mouth/face, and/or shortness of breath
- Skin rash/peeling, mouth ulcers
- Breathing problems, unexplained bruising/bleeding
- Signs of impaired liver function such as nausea, sudden weight loss, loss of appetite, and yellowing of the eyes and skin
How To Manage Side Effects
Diarrhea
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor if the diarrhea does not improve.
Dizziness Or Drowsiness
Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult your doctor if the dizziness worsens.
Nausea And Vomiting
Try to take NP COM TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the nausea and vomiting get worse.
Warning & Precautions
Pregnancy
ContraindicatedNP COM TABLET is not recommended for use during pregnancy. Consult your doctor before taking NP COM TABLET.
Breastfeeding
ContraindicatedNP COM TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking NP COM TABLET.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy, drowsy, and/or sleepy after taking NP COM TABLET.
Alcohol
ContraindicatedAvoid consumption of alcohol while taking NP COM TABLET because it might cause liver damage.
Kidney
Consult your doctorNP COM TABLET is not recommended for use in patients with severe kidney disease and/or analgesic nephropathy. It should be used with caution in patients with other kidney problems. Consult your doctor before taking NP COM TABLET.
Liver
ContraindicatedNP COM TABLET is not recommended in patients with liver disease. Consult your doctor before taking NP COM TABLET.
Allergy
ContraindicatedDo not take NP COM TABLET if you are allergic to nimesulide, paracetamol, other NSAIDS, and/or other ingredients of this medicine.
Heart Disease
Use with CautionNP COM TABLET should be used with caution in patients with heart failure. Consult your doctor before taking NP COM TABLET.
Use In Pediatrics
ContraindicatedNP COM TABLET is not recommended for use in children (aged below 12 years). Consult your doctor before administering the medicine to the child.
Use In Geriatrics
Use with CautionNP COM TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking NP COM TABLET.
Others
NP COM TABLET is not recommended for use if you:
- Have peptic ulcers and/or gastrointestinal bleeding
Before taking NP COM TABLET, inform your doctor if you:
- Are alcohol dependent
Interactions
A. Drug-drug interactions:
Before taking NP COM TABLET, inform your doctor if you are taking any of the following medicine:
- Anticoagulants (medicines used to manage blood clotting) Ex. warfarin
- Cholestyramine (medicine used to lower high cholesterol levels)
- Metoclopramide, domperidone (medicines used to manage nausea and vomiting)
B. Drug-food interaction:
Avoid consumption of foods containing caffeine and/or drinks such as tea, chocolate, and coffee since it leads to excessive dizziness and sleepiness.
Overdosage:
If you or anyone else accidentally took more of NP COM TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Nimesulide, Paracetamol |
| Pharmacological Category | : | Non-steroidal Anti-inflammatory drugs |
| Therapeutic Indication | : |
Osteoarthritic pain, Fever, Dysmenorrhea |
| Dosage Forms | : | Tablet, Capsule, Suspension |
More Information
Storage
- Keep NP COM TABLET out of reach of children
- Store NP COM TABLET in a cool, dry place
FAQs About NP COM TABLET
Q: What is NP COM TABLET used for?
A: NP COM TABLET is used for pain relief, headache, muscle pain, dental pain, joint pain, back pain, menstrual pain, sprains, strains, sports injuries, and other forms of painful conditions.
Q: When can I notice pain relief after using NP COM TABLET?
A: You may notice that your pain subsides within 1 hour of using NP COM TABLET. It may take a day to show significant effects. However, this period can vary from person to person based on their health condition.
Q: How long does it take for NP COM TABLET to show its effects?
A: You might observe that relief from your pain occurs within an hour of taking NP COM TABLET. Significant effects may take up to a day to manifest, although this timeframe can vary depending on individual health conditions.
Q: Is NP COM TABLET a good painkiller?
A: NP COM TABLET is commonly used as a painkiller and is generally considered effective for relieving various types of pain. It contains a combination of active ingredients, including nimesulide and paracetamol, which work together to alleviate pain and reduce inflammation. However, like any medication, its effectiveness can vary from person to person, and it's essential to use it as directed by a healthcare professional to ensure safety and maximum benefit. If you have specific concerns or medical conditions, it's advisable to consult with a doctor before using NP COM TABLET or any other painkiller.
Q: Does NP COM TABLET contain paracetamol?
A: Yes. NP COM TABLET is a combination of paracetamol and nimesulide, which collectively work together for alleviating pain and inflammation.
Q: Is NP COM TABLET used for fever?
A: Although NP COM TABLET contains paracetamol, a fever-reducing agent, at the dosage of 325 mg, it is effective in alleviating pain and inflammation rather than reducing fever. However, it can be used to control very mild fever and body pain in exceptional circumstances.
Q: Is NP COM TABLET good for stomach pain?
A: No. Do not take NP COM TABLET if you have stomach pain. As NP COM TABLET could generally increase your stomach acid secretion, it could worsen your existing condition. Therefore, check with your doctor for managing stomach pain.
Q: Can I consume two tablets of NP COM TABLET together for faster pain relief?
A: NP COM TABLET is usually prescribed as one tab (2–3 times daily). Taking two tablets in one shot may lead to overdosage and unnecessary reactions. Therefore, stick to the dosage and frequency suggested by your doctor. If you feel that the prescribed dose is not working well for you, inform your doctor. Your doctor might suggest a suitable alternative.
Q: Can I use NP COM TABLET for long-term?
A: NP COM TABLET is usually prescribed for short-term pain management. Taking it on a long-term basis without medical supervision may severely damage your liver and overall health. Therefore, consult your doctor before using it on a long-term basis.
Q: What are the long-term side effects of using NP COM TABLET?
A: NP COM TABLET should be used only for short-term periods. Long-term usage is more likely to cause liver damage. If you are using NP COM TABLET based on a doctor's advice, such unnecessary side effects can be avoided.
Q: Can I take NP COM TABLET daily?
A: NP COM TABLET can be taken daily if requested by your doctor. However, please note that it should be followed only for a short period of time (not more than 4 weeks).
Q: Does NP COM TABLET damage your liver?
A: Prolonged or overdosage of NP COM TABLET has been reported to cause liver damage. Hence, use this medicine for the exact duration as advised by your doctor and stop it.
Q: Is NP COM TABLET banned for use in children?
A: NP COM TABLET is not recommended for use in children under 12 years of age. Therefore, consult your doctor for advice.
Q: Does NP COM TABLET have side effects?
A: The most common side effects of NP COM TABLET are dizziness, excess sleepiness, stomach upset, nausea, abdominal discomfort, diarrhea, and/or peripheral oedema (swelling in the legs and arms). Consult your doctor if any of the symptoms worsen.
Q: Can NP COM TABLET be used in pregnant women?
A: Consult your doctor before taking NP COM TABLET if you are pregnant, as it is not known how this medicine reacts with an unborn baby.
Q: Can I consume alcohol while taking NP COM TABLET?
A: Avoid consumption of alcohol while taking NP COM TABLET because it might cause liver damage.
Q: What precautions must be taken while using NP COM TABLET?
A: Before taking NP COM TABLET, inform your doctor if you have a kidney problem, heart failure, or alcohol dependence.
Q: Who should not take NP COM TABLET?
A: Do not take NP COM TABLET if you are allergic to Nimesulide, Paracetamol, or other NSAIDS, or if you have severe kidney disease and/or analgesic nephropathy, liver disease, peptic ulcer, and/or gastrointestinal bleeding. Consult your doctor before taking it.
Q: Is NP COM TABLET safe for kids?
A: NP COM TABLET is not recommended for use in children (aged below 12 years). Consult your doctor before administering the medicine to the child.
References
1. KD Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic analgesics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 203,206.
2. Cristina Monteiro, Beatriz Dias, and Maria Vaz-Patto. Headache as an Adverse Reaction to the Use of Medication in the Elderly: A Pharmacovigilance Study. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. March 2021. [Accessed on 10th August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967518/
3. Crescent Pharma Limited. Electronic Medicines Compendium (EMC) [Revised in October 2021] [Accessed on 10th August 2024] https://www.medicines.org.uk/emc/files/pil.14044.pdf
4. Leeford Healthcare Limited. Nedolide-P. [Accessed on 10th August 2024] https://www.leeford.in/product/1046/nedolide-p
5. Orlife Healthcare Pvt. Ltd. Orflam-P. [Accessed on 10th August 2024] https://www.orlifehealthcare.com/product/orflam-p/
6. P&B Pharmaceuticals Ltd. Algiril tablet. [Accessed on 10th August 2024] http://www.pbpharma.co.in/algiril_tab.html
7. Pharmatech Healthcare. DIPLONIM-P Tab. [Accessed on 10th August 2024] http://www.pharmatechworld.com/product_division.php?page=2&id=2
8. Medlock Healthcare NICLOC-P. [Accessed on 10th August 2024] https://www.medlockhealthcare.in/product/nimesulide-100mg-paracetamol-325mg-
9. Nilrise Pharmaceuticals Pvt. Ltd. Zoynim-P Tablet. [Accessed on 10th August 2024] https://www.nilrisepharma.com/product/zoynim-p-tablet
10. Apikos Pharma. ORNIMOL-N. [Accessed on 10th August 2024] https://www.apikospharma.com/product/ornimol-n/
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