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Introduction About NORFLUR TZ 400/600MG TABLET
NORFLUR TZ 400/600MG TABLET is a combination of Norfloxacin and Tinidazole which belong to the group of medicines called Antibiotics and Antiprotozoal agents respectively. It is used in the management of diarrhea and dysentery of amoebic, bacterial, or mixed origins.
Before taking NORFLUR TZ 400/600MG TABLET, inform your doctor if you have lung, liver, or kidney disease or heart disorders. NORFLUR TZ 400/600MG TABLET is not recommended for patients with a history of hypersensitivity reactions, tendinitis, or tendon rupture, organic neurological disorders, or a history of blood dyscrasia. NORFLUR TZ 400/600MG TABLET is not recommended for use in pregnant and breastfeeding women. Contact your doctor before taking the medicine.
NORFLUR TZ 400/600MG TABLET is not recommended for use in children and adolescents under 18 years of age. Contact your doctor before taking. NORFLUR TZ 400/600MG TABLET should be used with caution in elderly patients aged above 65 years, especially patients with renal impairment. Contact your doctor before taking. The most common side effects of this medicine are nausea, decreased appetite, headache, dizziness, fatigue, rash, abdominal pain, and dyspepsia. Contact your doctor if any of the side effects worsen.
Uses Of NORFLUR TZ 400/600MG TABLET
- Used in the management of diarrhea and dysentery
How NORFLUR TZ 400/600MG TABLET Works
NORFLUR TZ 400/600MG TABLET is a combination of Norfloxacin and Tinidazole. Norfloxacin belongs to the fluoroquinolone that acts by stopping the multiplication of the disease-causing bacteria. Tinidazole belongs to nitroimidazole and acts against parasites and anaerobic bacteria that cause infections by damaging their DNA.
How to use NORFLUR TZ 400/600MG TABLET
Take this medicine as advised by your physician. Swallow this medicine as whole with a glass of water and do not crush or chew the medicine. Your doctor will decide the right dose depending on your age, body weight, and disease condition.
Side Effects Of NORFLUR TZ 400/600MG TABLET
Common
- nausea
- vomiting
- heartburn
- metallic taste
- headache
- dizziness
- insomnia
- rash
- dry mouth
- fever
- arthralgia
Rare
- eosinophilia
- bone marrow depression
- hypersensitivity reactions
- facial and laryngeal oedema
- hypotension
- bronchospasm
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the dizziness does not improve.
Headache
Rest and relax. Drink plenty of fluids, such as water or electrolytes, and apply a pain-relieving balm to the head if necessary. Do not consume alcohol. Contact your doctor if the headache does not improve.
Nausea And Vomiting
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if the nausea and vomiting do not improve.
Warning & Precautions
Pregnancy
ContraindicatedNORFLUR TZ 400/600MG TABLET is not recommended for use in pregnant women. Contact your doctor before taking the medicine.
Breastfeeding
ContraindicatedNORFLUR TZ 400/600MG TABLET is not recommended for use in breast feeding women. Contact your doctor before taking.
Kidney
Use with CautionNORFLUR TZ 400/600MG TABLET should be used with caution in patients with kidney disease. Contact your doctor before taking.
Allergy
ContraindicatedDo not take NORFLUR TZ 400/600MG TABLET if you are allergic to Norfloxacin, Tinidazole, or any other ingredients of this medicine.
Use In Pediatrics
ContraindicatedNORFLUR TZ 400/600MG TABLET is not recommended for use in children and adolescents under 18 years of age. Contact your doctor before taking.
Use In Geriatrics
Use with CautionNORFLUR TZ 400/600MG TABLET should be used with caution in elderly patients aged above 65 years, especially patients with renal impairment. Contact your doctor before taking.
Others
NORFLUR TZ 400/600MG TABLET is not recommended for use if you have:
- tendinitis, or tendon rupture
- organic neurological disorders
- a history of blood dyscrasia
Interactions
A. Drug-Drug interactions:
Before taking NORFLUR TZ 400/600MG TABLET, inform your physician if you are taking any of the following medicines:
- antacids (used to manage stomach ulcers)
B. Drug-Food interaction:
NORFLUR TZ 400/600MG TABLET may cause reduced absorption of Norfloxacin with milk or yogurt. Consult your doctor for advice.
Overdosage:
If you or anyone else accidentally takes too much of this medicine, consult your doctor immediately.
Synopsis
| Drug | : | Norfloxacin, Tinidazole |
| Pharmacological Category | : | Antibiotics, Anti-protozoals |
| Therapeutic Indication | : | Manages diarrhea and dysentery |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep out of reach of children
- Store NORFLUR TZ 400/600MG TABLET below 30°C
FAQs About NORFLUR TZ 400/600MG TABLET
Q: How does NORFLUR TZ 400/600MG TABLET work?
A: NORFLUR TZ 400/600MG TABLET is a combination of Norfloxacin and Tinidazole. Norfloxacin belongs to the fluoroquinolone that acts by stopping the multiplication of the disease-causing bacteria. Tinidazole belongs to nitroimidazole and acts against parasites and anaerobic bacteria that cause infections by damaging their DNA.
Q: What are the side effects of taking NORFLUR TZ 400/600MG TABLET?
A: The most common side effects of this medicine are nausea, decreased appetite, headache, dizziness, fatigue, rash, abdominal pain, and dyspepsia. Contact your doctor if any of the side effects worsen.
Q: Can I use NORFLUR TZ 400/600MG TABLET in children?
A: No. NORFLUR TZ 400/600MG TABLET is not recommended for use in children and adolescents below 18 years of age. Contact your doctor before taking the medicine.
Q: Can I use NORFLUR TZ 400/600MG TABLET while breastfeeding?
A: No. NORFLUR TZ 400/600MG TABLET is generally not recommended for use in breastfeeding women. Consult your doctor before taking it.
Q: Does NORFLUR TZ 400/600MG TABLET cause dizziness?
A: Yes. NORFLUR TZ 400/600MG TABLET may cause dizziness. Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the symptom does not improve.
Q: What is NORFLUR TZ 400/600MG TABLET used for?
A: NORFLUR TZ 400/600MG TABLET is used in the management of diarrhea and dysentery of amoebic, bacterial, or mixed origins.
Q: Is NORFLUR TZ 400/600MG TABLET safe for kidneys?
A: NORFLUR TZ 400/600MG TABLET should be used with caution in patients with kidney disease. Contact your doctor before taking.
Q: Who should not take NORFLUR TZ 400/600MG TABLET?
A: NORFLUR TZ 400/600MG TABLET is not recommended for use if you have tendinitis or tendon rupture, organic neurological disorders, a history of blood dyscrasia, or are allergic to Norfloxacin or Tinidazole.
Q: Can NORFLUR TZ 400/600MG TABLET be used in pregnant women?
A: NORFLUR TZ 400/600MG TABLET is not recommended for use in pregnant women. Contact your doctor before taking.
Q: How many days should I take NORFLUR TZ 400/600MG TABLET?
A: Take this medicine as advised by your physician. Swallow this medicine as whole with a glass of water and do not crush or chew the medicine. Your doctor will decide the right dose depending on your age, body weight, and disease condition.
References
1. K.D. Tripathi. Anti-fungal drugs and Antifungal and other antiprotozoal drugs. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page-793,839.
2. Bethesda. Tinidazole. National Institute of Health. National Library of Medicine. National Center for Biotechnology Information. Pubmed.gov. 2004. [Accessed on 12th August 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Tinidazole#section=Substances-by-Category
3. Leeford. [Accessed on 12th August 2024] https://www.leeford.in/product/1050/noxitef-tz
4. Wellona Pharma. [Accessed on 12th August 2024] https://wellonapharma.com/product/finished/norfloxacin-and-tinidazole-tablets
5. ATOZ Pharmaceuticals Pvt. Ltd. [Accessed on 12th August 2024] https://fdaghana.gov.gh/img/smpc/Nortiz%20400mg_600mg%20Tablets%20(Norfloxacin%20and%20Tinidazole).pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Kidney Function Test (KFT)
- Liver Function Test (LFT)
- Serum Electrolytes/ Electrolytes Profile
- Healthy Midlife Checkup
- Full Body Checkup - Gold
- Full Body Checkup - Silver
- Monsoon Gastro Infection Panel
- Gastro / Gut Health Panel

