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Introduction About NORFLOX TZ RF TABLET
NORFLOX TZ RF TABLET is a combination of Norfloxacin and Tinidazole which belong to the group of medicines called Antibiotics and Antiprotozoal agents respectively. It is used in the management of diarrhea and dysentery of amoebic, bacterial, or mixed origins.
Before taking NORFLOX TZ RF TABLET, inform your doctor if you have lung, liver, or kidney disease or heart disorders. NORFLOX TZ RF TABLET is not recommended for patients with a history of hypersensitivity reactions, tendinitis, or tendon rupture, organic neurological disorders, or a history of blood dyscrasia. NORFLOX TZ RF TABLET is not recommended for use in pregnant and breastfeeding women. Contact your doctor before taking the medicine.
NORFLOX TZ RF TABLET is not recommended for use in children and adolescents under 18 years of age. Contact your doctor before taking. NORFLOX TZ RF TABLET should be used with caution in elderly patients aged above 65 years, especially patients with renal impairment. Contact your doctor before taking. The most common side effects of this medicine are nausea, decreased appetite, headache, dizziness, fatigue, rash, abdominal pain, and dyspepsia. Contact your doctor if any of the side effects worsen.
Uses Of NORFLOX TZ RF TABLET
- Used in the management of diarrhea and dysentery
How NORFLOX TZ RF TABLET Works
NORFLOX TZ RF TABLET is a combination of Norfloxacin and Tinidazole. Norfloxacin belongs to the fluoroquinolone that acts by stopping the multiplication of the disease-causing bacteria. Tinidazole belongs to nitroimidazole and acts against parasites and anaerobic bacteria that cause infections by damaging their DNA.
How to use NORFLOX TZ RF TABLET
Take this medicine as advised by your physician. Swallow this medicine as whole with a glass of water and do not crush or chew the medicine. Your doctor will decide the right dose depending on your age, body weight, and disease condition.
Side Effects Of NORFLOX TZ RF TABLET
Common
- nausea
- vomiting
- heartburn
- metallic taste
- headache
- dizziness
- insomnia
- rash
- dry mouth
- fever
- arthralgia
Rare
- eosinophilia
- bone marrow depression
- hypersensitivity reactions
- facial and laryngeal oedema
- hypotension
- bronchospasm
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the dizziness does not improve.
Headache
Rest and relax. Drink plenty of fluids, such as water or electrolytes, and apply a pain-relieving balm to the head if necessary. Do not consume alcohol. Contact your doctor if the headache does not improve.
Nausea And Vomiting
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if the nausea and vomiting do not improve.
Warning & Precautions
Pregnancy
ContraindicatedNORFLOX TZ RF TABLET is not recommended for use in pregnant women. Contact your doctor before taking the medicine.
Breastfeeding
ContraindicatedNORFLOX TZ RF TABLET is not recommended for use in breast feeding women. Contact your doctor before taking.
Kidney
Use with CautionNORFLOX TZ RF TABLET should be used with caution in patients with kidney disease. Contact your doctor before taking.
Allergy
ContraindicatedDo not take NORFLOX TZ RF TABLET if you are allergic to Norfloxacin, Tinidazole, or any other ingredients of this medicine.
Use In Pediatrics
ContraindicatedNORFLOX TZ RF TABLET is not recommended for use in children and adolescents under 18 years of age. Contact your doctor before taking.
Use In Geriatrics
Use with CautionNORFLOX TZ RF TABLET should be used with caution in elderly patients aged above 65 years, especially patients with renal impairment. Contact your doctor before taking.
Others
NORFLOX TZ RF TABLET is not recommended for use if you have:
- tendinitis, or tendon rupture
- organic neurological disorders
- a history of blood dyscrasia
Interactions
A. Drug-Drug interactions:
Before taking NORFLOX TZ RF TABLET, inform your physician if you are taking any of the following medicines:
- antacids (used to manage stomach ulcers)
B. Drug-Food interaction:
NORFLOX TZ RF TABLET may cause reduced absorption of Norfloxacin with milk or yogurt. Consult your doctor for advice.
Overdosage:
If you or anyone else accidentally takes too much of this medicine, consult your doctor immediately.
Synopsis
| Drug | : | Norfloxacin, Tinidazole |
| Pharmacological Category | : | Antibiotics, Anti-protozoals |
| Therapeutic Indication | : | Manages diarrhea and dysentery |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep out of reach of children
- Store NORFLOX TZ RF TABLET below 30°C
FAQs About NORFLOX TZ RF TABLET
Q: What is Norflox-TZ RF Tablet used for?
A: Norflox-TZ RF Tablet is a combination of norfloxacin (an antibiotic) and tinidazole (an antiprotozoal) used to manage gastrointestinal infections, including diarrhea, dysentery, and traveler’s diarrhea caused by bacteria and protozoa. It helps eliminate infection and relieve symptoms like abdominal pain and loose stools.
Q: How should I take Norflox-TZ RF Tablet?
A: Take Norflox-TZ RF Tablet orally with water, preferably after meals to reduce stomach upset. Follow your doctor’s prescription regarding dosage and duration. Do not chew or crush the tablet.
Q: What are the common side effects of Norflox-TZ RF Tablet?
A: Common side effects include nausea, diarrhea, dizziness, headache, and abdominal pain. Rarely, it may cause allergic reactions, rashes, or tendon-related issues. Consult your doctor if side effects persist or worsen.
Q: Can I consume alcohol while taking Norflox-TZ RF Tablet?
A: Avoid alcohol while taking Norflox-TZ RF Tablet, as it may increase the risk of side effects like dizziness, flushing, and stomach upset. Tinidazole in the tablet may also cause a disulfiram-like reaction when combined with alcohol.
Q: Is Norflox-TZ RF Tablet safe during pregnancy and breastfeeding?
A: Norflox-TZ RF Tablet is not recommended during pregnancy unless deemed necessary by a doctor. During breastfeeding, it should be used cautiously as it may pass into breast milk. Always consult your doctor before using this medication if you are pregnant or breastfeeding.
Q: Can I stop taking Norflox-TZ RF Tablet if I feel better?
A: No, complete the full course of treatment as prescribed by your doctor. Stopping the medication early may lead to incomplete treatment and an increased risk of the infection returning or developing antibiotic resistance.
Q: Are there any specific contraindications for Norflox-TZ RF Tablet?
A: Norflox-TZ RF Tablet is contraindicated in individuals allergic to norfloxacin, tinidazole, or related medications. It is also not recommended for people with a history of tendon disorders, severe liver or kidney impairment, or epilepsy.
Q: Can Norflox-TZ RF Tablet be used for constipation?
A: No, Norflox-TZ RF Tablet is not indicated for constipation. It is specifically used to manage infections in the gastrointestinal tract and does not relieve constipation.
Q: What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to compensate for the missed one.
Q: Can Norflox-TZ RF Tablet cause tendon problems?
A: Yes, in rare cases, Norflox-TZ RF Tablet can cause tendon-related issues like inflammation, pain, or even tendon rupture. This is more common in older adults or individuals taking corticosteroids. Report any tendon pain or swelling to your doctor immediately.
References
1. K.D. Tripathi. Anti-fungal drugs and Antifungal and other antiprotozoal drugs. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page-793,839.
2. Bethesda. Tinidazole. National Institute of Health. National Library of Medicine. National Center for Biotechnology Information. Pubmed.gov. 2004. [Accessed on 12th August 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Tinidazole#section=Substances-by-Category
3. Leeford. [Accessed on 12th August 2024] https://www.leeford.in/product/1050/noxitef-tz
4. Wellona Pharma. [Accessed on 12th August 2024] https://wellonapharma.com/product/finished/norfloxacin-and-tinidazole-tablets
5. ATOZ Pharmaceuticals Pvt. Ltd. [Accessed on 12th August 2024] https://fdaghana.gov.gh/img/smpc/Nortiz%20400mg_600mg%20Tablets%20(Norfloxacin%20and%20Tinidazole).pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Kidney Function Test (KFT)
- Liver Function Test (LFT)
- Serum Electrolytes/ Electrolytes Profile
- Healthy Midlife Checkup
- Full Body Checkup - Gold
- Full Body Checkup - Silver
- Monsoon Gastro Infection Panel
- Gastro / Gut Health Panel
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