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Introduction About NODIMOX PLUS 500MG CAPSULE
NODIMOX PLUS 500MG CAPSULE contains a combination of Amoxicillin and Cloxacillin, which belongs to the group of medicines called semi-synthetic penicillin antibiotics. NODIMOX PLUS 500MG CAPSULE is used to manage infectious conditions caused by various types of bacteria such as lung infection (Bronchopneumonia, bronchitis etc.), infection in the blood (septicaemia), urinary tract infection, bone infection, wound infection and following a surgery etc. The symptoms of bacterial infection include fever, tiredness, headache, stomach pain, feeling sick or vomiting sensation etc.
Amoxicillin and Cloxacillin work by killing and managing the growth of bacteria by blocking the production of the bacterial cell wall. Before recommending NODIMOX PLUS 500MG CAPSULE, your doctor may want you to take relevant blood tests to understand your existing condition.
Before taking NODIMOX PLUS 500MG CAPSULE, inform your doctor if you have or ever had kidney disease (such as difficulty in passing urine, kidney failure, kidney injury etc.), liver disease, viral or fungal infection, malnutrition, suppressed immune system, bone marrow disorder, fits or seizure disorder, frequent diarrhoea etc. NODIMOX PLUS 500MG CAPSULE should be used with caution among women who are pregnant or breastfeeding. The most common side effects of taking NODIMOX PLUS 500MG CAPSULE are sickness, vomiting, skin rashes, itching, loose stools (diarrhoea), stomach upset or discomfort etc. Consult your doctor if any of the symptoms worsen.
Uses Of NODIMOX PLUS 500MG CAPSULE
NODIMOX PLUS 500MG CAPSULE is indicated for the management of the following bacterial infections:
- lung infection (bronchopneumonia, bronchitis etc.)
- infections in the blood (septicaemia)
- bone infection
- urinary tract infection
- wound infection
- stomach ulcer
- following a surgical procedure etc.
How NODIMOX PLUS 500MG CAPSULE Works
NODIMOX PLUS 500MG CAPSULE contains Amoxicillin and Cloxacillin, which work by blocking the production of the bacterial cell wall. As a result, NODIMOX PLUS 500MG CAPSULE kills and manages the growth of bacteria.
How to use NODIMOX PLUS 500MG CAPSULE
Take NODIMOX PLUS 500MG CAPSULE as directed by your physician. Swallow NODIMOX PLUS 500MG CAPSULE as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose, duration, and frequency depending on your age, body weight, other comorbid conditions, etc.
Side Effects Of NODIMOX PLUS 500MG CAPSULE
Common
- sickness
- vomiting
- skin rashes or itching
- loose stools (diarrhea)
- stomach upset or stomach discomfort
Rare
Stop taking NODIMOX PLUS 500MG CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, tongue and other parts of the body, difficulty in breathing or wheezing, blisters on the skin, sore throat, fever, headache etc.)
- severe joint pain, headache, muscle pain
- fever with high temperature, sore throat
- swollen lymph nodes
- redness or swelling in the skin surface
- tenderness in the area of the mouth, eyes and genitals
- itching and scaling of the skin
- abnormal white blood cells
- increase in the level of liver enzymes
- severe diarrhea with bleeding
- dark-colored urine
- change in color of the skin and the white part of the eye (yellowish color)
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Consult your doctor immediately if the symptoms worsen or persist.
Nausea And Vomiting
Take NODIMOX PLUS 500MG CAPSULE with, or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor immediately if the symptoms worsen or persist.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.
Warning & Precautions
Pregnancy
Use with CautionNODIMOX PLUS 500MG CAPSULE should be used with caution in pregnant women. Consult your doctor before taking it.
Breastfeeding
Use with CautionNODIMOX PLUS 500MG CAPSULE should be used with caution in breastfeeding mothers only if recommended by your doctor. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy, fits or seizure, abnormal body movements etc. after taking NODIMOX PLUS 500MG CAPSULE.
Kidney
Use with CautionNODIMOX PLUS 500MG CAPSULE should be taken with caution in patients with kidney disease (such as impaired kidney function, difficulty in passing urine etc.). Consult your doctor before taking.
Liver
Use with CautionNODIMOX PLUS 500MG CAPSULE should be used with caution in patients with liver disease (such as liver failure, jaundice etc.). Consult your doctor before taking.
Allergy
ContraindicatedDo not take NODIMOX PLUS 500MG CAPSULE if you are allergic to Amoxicillin or Cloxacillin. Also inform your doctor if you are allergic to beta-lactam antibiotics and other medicines such as cephalosporins, penicillins etc.
Heart Disease
Use with CautionNODIMOX PLUS 500MG CAPSULE should be used with caution in patients with heart conditions (such as on cardiopulmonary bypass support). Consult your doctor before taking.
Use In Pediatrics
Use with CautionNODIMOX PLUS 500MG CAPSULE should be used with caution in children. Consult your doctor before taking.
Use In Geriatrics
Use with CautionNODIMOX PLUS 500MG CAPSULE should be used with caution in the elderly. Consult your doctor before taking.
Others
Before taking NODIMOX PLUS 500MG CAPSULE, inform your physician if you have:
- poor immune system
- bleeding disorder – such as prolonged bleeding
- on a salt-restricted diet
- malnutrition
- fungal infection
- viral fever
Interactions
A. Drug-Drug interactions:
Before taking NODIMOX PLUS 500MG CAPSULE, inform your doctor if you are taking any of the following medicine:
- probenecid, allopurinol – used to manage gout or arthritis
- oral contraceptives - used to abort the pregnancy
- warfarin – used to manage blood clots
- tetracycline – used to manage the bacterial infection
- methotrexate – used in the management of cancer and psoriasis
B. Drug-Food interaction:
The possible interaction of food while taking NODIMOX PLUS 500MG CAPSULE is not known. Consult your doctor for advice.
Overdosage:
If you or anyone else accidentally take too much of NODIMOX PLUS 500MG CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are sickness, vomiting, diarrhoea etc.
Synopsis
| Drug | : | Amoxicillin, Cloxacillin |
| Pharmacological Category | : | Penicillin antibiotics |
| Therapeutic Indication | : | To manage systemic bacterial infection |
| Dosage Forms | : | Capsule, Tablet, Syrup, Suspension, Injection |
More Information
- Keep out of reach from children
- Store at room temperature
FAQs About NODIMOX PLUS 500MG CAPSULE
Q: Can [GBBNKEYWORD] cause diarrhoea?
A: The common side effect of taking NODIMOX PLUS 500MG CAPSULE includes sickness, vomiting, skin rashes or itching, loose stools (diarrhoea), stomach upset or stomach discomfort. If your experience symptoms such as diarrhoea drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Consult your doctor immediately if the symptoms worsen or persist.
Q: Is NODIMOX PLUS 500MG CAPSULE safe for use in pregnant women?
A: NODIMOX PLUS 500MG CAPSULE should be used with caution in pregnant women only if recommended by your doctor. Your doctor will evaluate your condition to determine the risks and benefits before recommending you this medicine.
Q: Is NODIMOX PLUS 500MG CAPSULE safe for use in patients on blood thinner medications?
A: NODIMOX PLUS 500MG CAPSULE should be used with caution if you are on other medication. Inform your doctor if you are taking any of the medicines. Your doctor will evaluate the possible risks and benefits before recommending you this medicine.
Q: Can NODIMOX PLUS 500MG CAPSULE cause allergy?
A: Yes. NODIMOX PLUS 500MG CAPSULE can cause allergic reactions and its symptoms include skin rash, itching, swelling of the face, lips, tongue and other parts of the body, difficulty in breathing or wheezing, blisters on the skin, sore throat, fever, headache etc. Stop taking this medicine if have an allergic reaction and consult your doctor immediately.
Q: Is NODIMOX PLUS 500MG CAPSULE safe for use in patients with liver disease?
A: NODIMOX PLUS 500MG CAPSULE should be used with caution in patients with liver diseases such as impaired liver function, jaundice, hepatitis etc. Your doctor may advise relevant medical tests to understand your condition before recommending you this medicine.
References
1. KD. Tripathi. Beta-lactam antibiotics. Essentials of medical pharmacology. 8th Edition. 2019. Page – 773 & 771.
2. Do T Giang and Vu D Hoang. Comparative Study of RP-HPLC and UV Spectrophotometric Techniques for the Simultaneous Determination of Amoxicillin and Cloxacillin in Capsules. [Revised on June 2010] [Accessed On 10th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021696/
3. Maxheal Pharmaceuticals (India) Ltd. National Agency for Food & Drug Administration & Control (NAFDAC). Ampicillin and Cloxacillin Capsule 500 mg. [Accessed On 10th May 2022] https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/DEC_21/Greenfield-Ampicillin-and-Cloxacillin-Capsules-500mg.pdf
4. Teva Canada Limited. Teva-cloxacillin. [Revised on 21st June 2018] [Accessed On 10th May 2022] https://pdf.hres.ca/dpd_pm/00046029.PDF
5. Milpharm Limited. Electronic Medicines Compendium (EMC). Amoxicillin 250 mg Capsules, Amoxicillin 500 mg Capsules. [Revised on February 2022] [Accessed On 10th May 2022] https://www.medicines.org.uk/emc/files/pil.526.pdf
Useful Diagnostic Tests
- CBP
- LFT
- KFT
- Random blood glucose level
- Fasting blood glucose level
- HBA1c
- Oral glucose tolerance test
- Capillary blood glucose (home monitoring)
- PT -INR
- BT/CT - test
- Urine test for blood sugar (glucose)
- Stool examination test
- USG abdomen
- MRI, CT scan
- Culture sensitivity test
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