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Introduction About NOBEL 200MG TABLET
NOBEL 200MG TABLET contains Nimesulide, which belongs to the group of medicines called Non-steroidal anti-inflammatory drugs (NSAIDs). It is used to manage inflammatory conditions, including joint disorders such as rheumatoid arthritis, posttraumatic and postoperative painful conditions, and fever. NOBEL 200MG TABLET is also used to manage acute pain in orthopaedic, ENT, dental, and mild to moderate pain of osteoarthritis and rheumatoid arthritis.
Your doctor might advise regular liver function tests during management with NOBEL 200MG TABLET.
NOBEL 200MG TABLET is usually advised as a second line of management for a short duration of time in order to relieve symptoms.
NOBEL 200MG TABLET is not recommended in cases of active stomach or duodenal ulcers, alcoholism, drug addiction, cerebrovascular bleeding or bleeding disorders, severe clotting disorders, severe heart, kidney, or liver impairment, fever and/or flu-like symptoms, a history of recurrent ulceration, or gastrointestinal bleeding.
NOBEL 200MG TABLET is not recommended during the third trimester of pregnancy and in breast-feeding women.
NOBEL 200MG TABLET is not given to children and adolescents below 12 years of age. It should be used with caution in elderly patients.
The most common side effects of taking NOBEL 200MG TABLET are vomiting, diarrhea or nausea, and changes in the level of liver enzymes. Consult your doctor if the above side effects do not improve.
Uses Of NOBEL 200MG TABLET
It is used to manage inflammatory conditions, including joint disorders such as:
- rheumatoid arthritis
- post traumatic
- postoperative painful condition and
- fever
How NOBEL 200MG TABLET Works
NOBEL 200MG TABLET works by blocking the enzyme involved in the production of certain chemical substances during inflammation, which are responsible for causing pain, redness, swelling, and fever in the body. Hence decreasing the fever, pain, and swelling caused after injuries.
How to use NOBEL 200MG TABLET
Take NOBEL 200MG TABLET as advised by your physician. It can be taken with or without meals.
For Tablet, Capsule: Swallow NOBEL 200MG TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse NOBEL 200MG TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition. Continue to take NOBEL 200MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.
Side Effects Of NOBEL 200MG TABLET
Common
- diarrhoea
- nausea
- vomiting
- elevated liver enzymes
Uncommon
- skin itching, eruptions
- increased sweating
- constipation
- flatulence
- gastrointestinal bleeding
- ulcers and perforation in stomach, duodenum
- high blood pressure
- dizziness
- breathing difficulty
- edema
Rare
- decreased red blood cells and low hemoglobin
- high level of disease-fighting white blood cells (eosinophils)
- allergic skin reactions
- increased blood potassium level
- anxiety, nervousness, and nightmares
- blurred vision
- increased heart rate, fluctuation in blood pressure, and hot flushes
- Inflamed skin and redness
- tiredness, decreased muscle strength
- blood in urine and difficulty in urinating
- pain or burning sensation while urinating
Stop taking NOBEL 200MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reactions like rashes, mucosal lesions (exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis)
- signs of liver injury (anorexia, nausea, vomiting, abdominal pain, fatigue, dark urine, or abnormal liver function tests)
- gastrointestinal bleeding or ulceration/perforation, stools with blood
- signs of fever like chills, shivering, feeling of uneasiness
How To Manage Side Effects
Diarrhea
Drink lots of fluids, like water and fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. If the diarrhea does not improve, contact your doctor.
Nausea And Vomiting
Take this medicine just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. If the nausea and vomiting do not improve, contact your doctor.
Warning & Precautions
Pregnancy
Monitoring requiredNOBEL 200MG TABLET is not recommended for use in the third trimester of pregnancy and women planning to have a baby because it may cause many malformations in neonates. If needed, the dose will be adjusted by your doctor. Consult your doctor before taking.
Breastfeeding
ContraindicatedNOBEL 200MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate machinery if you feel dizzy, have a head spinning sensation, or have excessive sleepiness after taking NOBEL 200MG TABLET.
Alcohol
ContraindicatedConsumption of alcohol is not recommended while taking NOBEL 200MG TABLET.
Kidney
ContraindicatedNOBEL 200MG TABLET is not recommended for use in patients with severe impairment in kidney function. Consult your doctor before taking it.
Liver
ContraindicatedNOBEL 200MG TABLET is not recommended for use in patients with severe impaired liver function and liver failure. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take NOBEL 200MG TABLET if you are allergic to Nimesulide or any history of hypersensitivity reactions (Ex. bronchospasm, rhinitis, urticarial, nasal polyps) or any ingredients of this medicine.
Heart Disease
Consult your doctorNOBEL 200MG TABLET is not recommended for use in patients with severe heart failure. It should be used with caution in patients with impaired heart function, uncontrolled hypertension, established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease. Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedNOBEL 200MG TABLET is not recommended for children and adolescents below 12 years of age. Consult your doctor before taking it.
Use In Geriatrics
Use with CautionNOBEL 200MG TABLET should be used with caution in elderly patients as they are more susceptible to the adverse effects. Consult your doctor before taking it.
Others
NOBEL 200MG TABLET is not recommended for use if you:
- have drug addiction problems
- have cerebrovascular bleeding or other active bleeding or bleeding disorders
- have severe clotting disorders
- have an active or history of gastric or duodenal ulcers or gastrointestinal bleeding
- have signs of flu or fever
Before taking NOBEL 200MG TABLET, inform your doctor if you:
- have peptic ulcer, ulcerative colitis, or Crohn's disease
Interactions
A. Drug-Drug interactions:
Before taking NOBEL 200MG TABLET, inform your doctor if you are taking any of the following medicine:
- other medicine used to reduce inflammation (Ex. methylprednisolone)
- medicine used to manage blood clots (Ex. warfarin)
- medicine used in management of arthritis (Ex. methotrexate)
- medicines used in the management of mental disorders (Ex. lithium)
- diuretics (Ex. furosemide) to rid the body of salt and water
Overdosage:
If you or anyone else accidentally takes too much NOBEL 200MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are drowsiness, sluggishness, nausea, vomiting, and abdominal discomfort.
Synopsis
| Drug | : | Nimesulide |
| Pharmacological Category | : | Sulphonanilides |
| Therapeutic Indication | : | Manages Musculoskeletal pain |
| Dosage Forms | : | Tablet, Capsule, Injection, Gel, Suspension |
More Information
Storage
- Keep NOBEL 200MG TABLET out of reach of children
- Store at room temperature
FAQs About NOBEL 200MG TABLET
Q: What is the use of NOBEL 200MG TABLET?
A: NOBEL 200MG TABLET is used for pain relief, headache, muscle pain, dental pain, joint pain, back pain, menstrual pain, sprains, strains, sports injuries, and other forms of painful conditions.
Q: When can I notice pain relief after using NOBEL 200MG TABLET?
A: You may notice that your pain subsides within 1 hour of using NOBEL 200MG TABLET. It may take a day to show significant effects. However, this period can vary from person to person based on their health condition.
Q: Can NOBEL 200MG TABLET be taken for a longer duration?
A: No, NOBEL 200MG TABLET is not recommended for a long period of time as it can lead to serious symptoms like ulcers and bleeding in the stomach. It is also known to cause kidney problems if taken for a long period of time. Therefore, take this medicine only for the duration specified by your physician.
Q: Can NOBEL 200MG TABLET be taken along with food?
A: NOBEL 200MG TABLET is usually taken with food to avoid gastrointestinal side effects. It should not be taken with an empty stomach, as it can lead to discomfort and irritation in the stomach along with pain. Consult your doctor before taking it.
Q: Is NOBEL 200MG TABLET good for stomach pain?
A: No. Do not take NOBEL 200MG TABLET if you have stomach pain. As it could generally increase your stomach acid secretion, it could worsen your existing condition. Therefore, check with your doctor for managing stomach pain.
Q: What are the long-term side effects of using NOBEL 200MG TABLET?
A: NOBEL 200MG TABLET should be used only for short-term periods. Long-term usage is more likely to cause liver damage. If you are using NOBEL 200MG TABLET based on a doctor's advice, such unnecessary side effects can be avoided.
Q: Can I take NOBEL 200MG TABLET daily?
A: NOBEL 200MG TABLET can be taken daily if requested by your doctor. However, please note that it should be followed only for a short period of time (not more than 4 weeks).
Q: Does NOBEL 200MG TABLET damage your liver?
A: prolonged or overdosage of NOBEL 200MG TABLET has been reported to cause liver damage. Hence, use this medicine for the exact duration as advised by your doctor and stop it.
Q: Is NOBEL 200MG TABLET banned for use in children?
A: NOBEL 200MG TABLET is not recommended for use in children under 12 years of age. Therefore, consult your doctor for advice.
Q: Does NOBEL 200MG TABLET have side effects?
A: The most common side effects of NOBEL 200MG TABLET are dizziness, excess sleepiness, stomach upset, nausea, abdominal discomfort, diarrhea, and/or peripheral oedema (swelling in the legs and arms). Consult your doctor if any of the symptoms worsen.
Q: Can NOBEL 200MG TABLET be used in pregnant women?
A: Consult your doctor before taking NOBEL 200MG TABLET if you are pregnant, as it is not known how this medicine reacts with an unborn baby.
Q: Who should not take NOBEL 200MG TABLET?
A: Do not take NOBEL 200MG TABLET if you are allergic to Nimesulide or other NSAIDS, or if you have severe kidney disease and/or analgesic nephropathy, liver disease, peptic ulcer, and/or gastrointestinal bleeding. Consult your doctor before taking it.
Q: Does NOBEL 200MG TABLET make you dizzy?
A: Yes, NOBEL 200MG TABLET can make you feel dizzy. Therefore, it is not advised to not drive or do any tiring work if you feel these symptoms, as it may cause great harm. If you feel this symptom is disturbing, consult your doctor for advice.
Q: Does NOBEL 200MG TABLET cause diarrhea?
A: Yes, NOBEL 200MG TABLET cause diarrhea. Drink lots of fluids, like water and fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. If the diarrhea does not improve, contact your doctor.
References
1. KD Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh Edition, 2013. Page - 203-204.
2. H G Kress, A Baltov, A Basinski, F Berghea, J Castellsague, C Codreanu, E Copaciu, M A Giamberardino, M Hakl, L Hrazdira, M Kokavec, J Lejcko, L Nachtnebl, R Stancík, A Švec, T Tóth, M V Vlaskovska, J Woron. Acute pain: a multifaceted challenge—the role of nimesulide. NIH: National Library of Medicine, National Center of Biotechnology Information Pubmed.gov. 2016. [Accessed on 10th August 2024] https://pubmed.ncbi.nlm.nih.gov/26414386/
3. A K Singla, M Chawla, A Singh. Nimesulide: some pharmaceutical and pharmacological aspects—an update. NIH: National Library of Medicine, National Center of Biotechnology Information Pubmed.gov. 2000. [Accessed on 10th August 2024] https://pubmed.ncbi.nlm.nih.gov/10864134/
4. Magis Farmaceutici. Isodol. (Nimesulide 100 mg). [Revised in July 2022] [Accessed on 10th August 2024] https://www.magispharma.it/media/isodol/download/en/15700031575d9458d58342b.pdf
5. Pharm Evo Pvt Ltd. NOBEL 200MG TABLET (Nimesulide 100mg). [Revised on May 2016] [Accessed on 10th August 2024] https://pharmevo.biz/wp-content/uploads/2021/03/Nise.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Liver Function Test (LFT)
- Kidney Function Test (KFT)
- Rheumatoid Factor (RF)/RA Test Rheumatoid Arthritis Factor, Qualitative
- Basic Arthritis Care
- Advance Bone Care
- Esr Automated
- Extended Arthritis Care Plan
- Bone Strength Package
- Autoimmune Arthritis Panel
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