NIZOCLIN SX 2% LOTION 100ML

Introduction About NIZOCLIN SX 2% LOTION

NIZOCLIN SX 2% LOTION contains Ketoconazole which belongs to the group of medicines called Antifungals. It is used in adults to manage fungal and yeast infections which may appear on the skin of the hands, feet, genital area, trunk, groin, scalp, face, chest or back.

NIZOCLIN SX 2% LOTION is not recommended for eye infections. Before applying NIZOCLIN SX 2% LOTION, inform your doctor if you are using a cream, ointment or lotion that contains a steroid.

NIZOCLIN SX 2% LOTION can be used if you are pregnant or breast-feeding, however, consult your doctor for advice. NIZOCLIN SX 2% LOTION is not recommended for use in children and adolescents (under 18 years of age).

The most common side effects of applying NIZOCLIN SX 2% LOTION are burning sensation, skin redness, or itching. If any of the symptoms worsen, contact your doctor.

Uses Of NIZOCLIN SX 2% LOTION

Manages the fungal or yeast infections of skin appearing on:

• trunk, chest, back
• hands, feet
• scalp, face
• groin, genitals

How NIZOCLIN SX 2% LOTION Works

NIZOCLIN SX 2% LOTION reduces fungal infection by inhibiting the growth of the fungus by weakening the structure and function of the fungal cell membrane.

How to use NIZOCLIN SX 2% LOTION

Apply NIZOCLIN SX 2% LOTION as advised by your physician. It is for external use only. Wash the infected area and dry it well.  Apply it to the affected and immediate surrounding area with clean fingers. Unless the affected skin is on your hands, wash your hands with soap and water after using NIZOCLIN SX 2% LOTION in order to stop you from spreading the infection to other parts of your body or to other people.

Keep using NIZOCLIN SX 2% LOTION until a few days after all symptoms have completely disappeared. This is to manage your symptoms from recurring.

Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Usually, you will see improvement after 4 weeks but if you don’t, talk to your doctor.

Side Effects Of NIZOCLIN SX 2% LOTION

How To Manage Side Effects

Rash:

Applying a cold compress, damp cloth, or cool showers can bring immediate relief to swelling and reduce itching. Avoid hot showers because hot water can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash persists.

Warning & Precautions

Pregnancy

NIZOCLIN SX 2% LOTION can be used if you are pregnant, however, consult your doctor for advice.

Breastfeeding

NIZOCLIN SX 2% LOTION can be used if you are breast-feeding, however, consult your doctor for advice.

Driving and Using Machines

NIZOCLIN SX 2% LOTION is unlikely to affect your ability to drive or to use machinery.

Allergy

Do not apply NIZOCLIN SX 2% LOTION if you are allergic to Ketoconazole or any of the other ingredients of this medicine.

Interactions

A. Drug - Drug interactions:

Before applying NIZOCLIN SX 2% LOTION, inform your doctor if you are using the following medicines:

• medicines used to manage inflammatory conditions (Ex. betamethasone, hydrocortisone)

Overdosage:

If you or anyone else accidentally apply too much of NIZOCLIN SX 2% LOTION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include burning sensation, redness or swelling.

Synopsis

More Information

• Keep NIZOCLIN SX 2% LOTION out of reach of children
• Do not store above 25°C

FAQs About NIZOCLIN SX 2% LOTION

How often should I apply NIZOCLIN SX 2% LOTION?

Your doctor will decide the correct dose and duration of NIZOCLIN SX 2% LOTION for you depending upon your age, body weight and disease condition. Depending on the infection type, management may last 2 to 6 weeks. Do not apply it for more duration than advised by your doctor.

What if I swallow NIZOCLIN SX 2% LOTION?

Accidental swallowing of small quantities of NIZOCLIN SX 2% LOTION is usually harmless but, consult your doctor immediately if you or anyone else swallow it. Take the medicine with you for the doctor to know what you have ingested.

How do I apply NIZOCLIN SX 2% LOTION?

Apply NIZOCLIN SX 2% LOTION as directed by your physician. Wash the infected area and dry it properly. Keep a towel and a flannel for your personal use to manage infecting anyone else. Apply the medicine gently into the affected area and surrounding skin with clean fingers. Clothing which touches the infected areas should be washed and changed frequently. Consult your doctor if you have any doubts regarding its use.

What if I forget to apply NIZOCLIN SX 2% LOTION?

If you forget to apply NIZOCLIN SX 2% LOTION, use as per the directions next time you apply it. Do not use the medicine two times to make up for the missed dose.

Can I stop applying NIZOCLIN SX 2% LOTION?

Do not stop applying NIZOCLIN SX 2% LOTION without asking your doctor. You will usually see signs of improvement after 4 weeks. If not, talk to your doctor. Continue using the medicine until a few days after all symptoms have completely disappeared. Even after your skin is completely managed, you sometimes have to apply the medicine once weekly or once per 2 weeks to manage your symptoms from coming back.

Can I use other medicines with NIZOCLIN SX 2% LOTION for my skin condition?

Before using NIZOCLIN SX 2% LOTION, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, over the counter or any herbal medicine. If you have been regularly using a lotion or cream, containing a steroid (Ex. betamethasone or hydrocortisone) for your skin condition, you should wait for two weeks before starting management with NIZOCLIN SX 2% LOTION. This will stop your condition flaring up while NIZOCLIN SX 2% LOTION starts to work. If you have any queries about stopping your steroid lotion or cream, consult your doctor.

References

1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 791, 792.

2. Hadeer Sinawe, Damian Casadesus. Ketoconazole. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. June 2022. [Accessed 18th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK559221/

3. Choi FD, Juhasz MLW, Atanaskova Mesinkovska N. Topical ketoconazole: a systematic review of current dermatological applications and future developments. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. October 1987. [Accessed on 18th October 2022] https://pubmed.ncbi.nlm.nih.gov/30668185/

4. Janssen Pharmaceutica NV. Health Products Regulatory Authority (HPRA). [Revised in July 2022] [Accessed on 18th October 2022] https://www.hpra.ie/img/uploaded/swedocuments/4bf3b755-f85e-41e5-916a-b7c9a7fc10d6.pdf

5. Janssen Pharmaceutica NV. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed 18th October 2022] https://www.medicines.org.uk/emc/files/pil.970.pdf

6. Palsons Derma. Novale scalp lotion (Ketoconazole 2%). [Accessed on 18th October 2022] https://www.palsonsderma.com/novale-scalp-lotion

7. Praise Pharma. Esava ointment. (Ketoconazole 2%). [Accessed on 18th October 2022] http://www.praisepharma.com/products/anti-fungal_esava-ointment.html

Useful Diagnostic Tests

• Microscopic examination of skin

Author Details

Written By Dr. Jeenal Rajani - Pharm.D.

Reviewed For Accuracy By Dr. Nitin Sattiwale - MBBS

Last updated on 22 Oct 2022 | 07:04 PM(IST)