Nixidox Capsule 10'S
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Introduction About NIXIDOX CAPSULE
NIXIDOX CAPSULE is a combination of Doxycycline and Lactic Acid Bacillus, which belong to the groups of medicines called antibiotics and probiotics, respectively. It is used in adults prone to intra-abdominal bacterial infection and to manage antibiotic-associated diarrhoea.
Before taking NIXIDOX CAPSULE, inform your doctor about your pre-existing conditions, allergies or if you are taking any other medicines. NIXIDOX CAPSULE is not recommended for use in pregnant women, breastfeeding women or children (younger than 8 years), so consult your doctor before taking it.
The most common side effects of taking NIXIDOX CAPSULE are loss of appetite, nausea, vomiting, diarrhoea, rash, light sensitivity, hives and haemolytic anaemia. Consult your doctor if any of your symptoms get worse.
Uses Of NIXIDOX CAPSULE
- Manage intra-abdominal bacterial infection
- Manage antibiotic-associated diarrhea
How NIXIDOX CAPSULE Works
NIXIDOX CAPSULE improves gastrointestinal symptoms where doxycycline gets accumulated inside the bacteria, gets attached to the 30S subunit of the bacterial ribosome and inhibits bacterial protein synthesis; lactobacillus restores the natural microbial flora within the digestive tract and helps in the breakdown of food, resulting in the production of lactic acid, hydrogen peroxide and other by-products.
How to use NIXIDOX CAPSULE
Take NIXIDOX CAPSULE as advised by your physician. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Your doctor will determine your correct dose and duration based on your age, body weight and disease condition.
Side Effects Of NIXIDOX CAPSULE
Common
- loss of appetite, nausea, vomiting, diarrhea
- rash, light sensitivity, hives
- hemolytic anemia (red blood cells are destroyed faster than they can be restored)
Rare
Stop taking NIXIDOX CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- permanent discoloration of the teeth to yellow-grey-brown (second half of pregnancy, infancy and childhood up to 8 years of age)
- clostridium difficile-associated diarrhea
- light sensitivity causing extreme sunburn reaction
How To Manage Side Effects
Loss of appetite:
Eat when you are hungry. Eat smaller meals more often than usual. Snack only when you're hungry. Eat a nutritious snack rich in calories and protein, such as dried fruit and nuts. Consult your doctor if your symptom does not improve or persist.
Nausea:
Take NIXIDOX CAPSULE with or just after, meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if your symptom does not improve or persist.
Vomiting:
Get adequate rest. Drink lots of fluids, especially water. Have small sips if you feel sick. Eat when you feel like eating; you don't have to eat or avoid any specific foods. Do not take any medicine for vomiting without your doctor's consultation. Consult your doctor if your symptom does not improve or persist.
Diarrhoea:
Drink lots of fluids, like water or fruit juice, to keep yourself hydrated. Check with your doctor before taking any medicine for diarrhoea. Consult your doctor if your symptom does not improve or persist.
Warning & Precautions
Pregnancy
NIXIDOX CAPSULE is not recommended for use by pregnant women. Consult your doctor before taking it.
Breastfeeding
NIXIDOX CAPSULE is not recommended for use by breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Consult your doctor if you feel any side effects during management with NIXIDOX CAPSULE that may stop you from driving or using machines.
Allergy
Do not take NIXIDOX CAPSULE if you are allergic to Doxycycline, Lactic acid bacillus, other tetracyclines or any of the other ingredients of this medicine.
Others
Before taking NIXIDOX CAPSULE, inform your doctor about your pre-existing conditions.
Use in Pediatrics:
NIXIDOX CAPSULE is not recommended for use by children under 8 years of age. Consult your doctor before taking it.
Use in Geriatrics:
Your doctor will prescribe the right dose of NIXIDOX CAPSULE depending on your age, body weight and health condition. Consult your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking NIXIDOX CAPSULE, inform your doctor if you are taking any of the following medicines:
- medicines used to manage blot clots (Ex. dabigatran, rivaroxaban)
- medicines used to reduce acidity (Ex. aluminum, calcium, magnesium, bismuth subsalicylate)
- iron-containing medicines
- medicines used to manage pregnancy (Ex. norethindrone, ethinyl estradiol)
- medicines used to manage fits (Ex. phenobarbital, carbamazepine, phenytoin)
Overdosage:
If you or anyone else accidentally take too much of NIXIDOX CAPSULE, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Doxycycline, Lactic acid bacillus |
| Pharmacological Category | : | Tetracycline antibiotics, Probiotics |
| Therapeutic Indication | : | Intra-abdominal bacterial infection, Antibiotic associated diarrhoea |
| Dosage Forms | : | Tablet, Capsule |
More Information
- Keep NIXIDOX CAPSULE out of reach from children
- Store below 30°C
FAQs About NIXIDOX CAPSULE
Can NIXIDOX CAPSULE be given to children?
NIXIDOX CAPSULE is not recommended for use in children (under 8 years of age) as it may cause permanent discoloration of teeth. Your doctor will decide on the correct dose or select a suitable alternative management for your child.
What if I forget to take a dose of NIXIDOX CAPSULE?
If you forget to take a dose of NIXIDOX CAPSULE, take it as soon as you remember. However, omit the missed dose if it's almost time for the next one. Do not take the medicine twice to make up for the missed dose.
Can NIXIDOX CAPSULE be stopped?
Continue taking NIXIDOX CAPSULE until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or new symptoms. Contact your doctor in such a case.
How should NIXIDOX CAPSULE be taken? Can it be crushed?
No. Do not break, crush or chew NIXIDOX CAPSULE. Take it as advised by your physician. Swallow it with a glass of water. Your doctor will determine your correct dose and duration based on your age, body weight and disease condition.
What is NIXIDOX CAPSULE used for?
NIXIDOX CAPSULE is used in adults prone to intra-abdominal bacterial infection and antibiotic-associated diarrhoea.
Can NIXIDOX CAPSULE cause vomiting?
Vomiting is a common side effect of NIXIDOX CAPSULE. In such cases, get adequate rest and drink lots of fluids, especially water. Have small sips if you feel sick. Eat when you feel like eating; you don't have to eat or avoid any specific foods. Do not take any medicine for vomiting without your doctor's consultation. If vomiting does not get better, contact your doctor.
What should I tell my doctor before taking NIXIDOX CAPSULE?
Patients taking NIXIDOX CAPSULE must inform their doctor about their pre-existing conditions or allergies. Patients should also tell their doctor if they are pregnant or breastfeeding. Consult your doctor if you experience anything different.
Can NIXIDOX CAPSULE be taken during pregnancy?
NIXIDOX CAPSULE is not recommended for use in pregnancy. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before taking it. Inform your doctor immediately if you become pregnant during this management.
Can I take other medicines with NIXIDOX CAPSULE?
Before taking NIXIDOX CAPSULE, inform your doctor if you have taken or might take any other medicine, including prescription, over-the-counter or herbal medicine, as these might cause serious side effects by interacting with each other.
References
1. Sean C Sweetman. Antibacterials. Martindale The Complete Drug Reference. 36th edition. Page- 267.
2. Mu Q, Tavella VJ, Luo XM. Role of Lactobacillus reuteri in Human Health and Diseases. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. April 2018. [Accessed on 11th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917019/
3. Micro Labs Ltd. Doxycycline + Lactobacillus. [Accessed on 11th August 2022] http://www.microlabsltd.com/elibrary/node/2315
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