Nixide 100mg Suspension 30ml

Introduction About NIXIDE 100MG SUSPENSION

NIXIDE 100MG SUSPENSION contains Nitazoxanide which belongs to the group of medicines called Antiprotozoals. It is used to manage diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.

Avoid consumption of alcohol while taking this medicine. NIXIDE 100MG SUSPENSION is not effective for the management of diarrhoea caused by C. parvum in HIV-infected or immunodeficient patients. Before taking NIXIDE 100MG SUSPENSION, inform your doctor if you have diabetes, kidney, liver, biliary problems.

NIXIDE 100MG SUSPENSION should be used with caution among pregnant women and breastfeeding women as safety data has not been established yet. Safety and effectiveness of NIXIDE 100MG SUSPENSION in children below 1 year of age has not been established yet. It should be used with caution in elderly patients above 65 years of age.

The most common side effects of taking NIXIDE 100MG SUSPENSION are abdominal pain, diarrhoea, headache, and nausea. Contact your doctor if any of the above symptoms worsen.

Uses Of NIXIDE 100MG SUSPENSION

• to manage diarrhea caused by Giardia lamblia or Cryptosporidium parvum

How NIXIDE 100MG SUSPENSION Works

NIXIDE 100MG SUSPENSION works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa causing diarrhoea.

How to use NIXIDE 100MG SUSPENSION

Take NIXIDE 100MG SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Side Effects Of NIXIDE 100MG SUSPENSION

How To Manage Side Effects

Headache: 

Rest and relax. Keep yourself hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of alcohol. If the symptom does not improve, contact your physician for advice.

Nausea:

Stick to simple meals. Avoid eating oil-rich or spicy foods. If the symptom does not improve, contact your physician for advice.

Diarrhoea:

Drink more fluids like water or fruit juice to keep yourself hydrated. Do not take any medicine on your own for diarrhoea without consulting your physician. If the symptom does not improve, contact your physician for advice.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have lesser and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your physician for advice.

Warning & Precautions

Pregnancy

NIXIDE 100MG SUSPENSION should be used with caution in pregnant women or women planning to have a baby as safety data has not been established yet. Consult your doctor before taking it.

Breastfeeding

NIXIDE 100MG SUSPENSION should be used with caution in breastfeeding women as it is not known if it is excreted in breastmilk. Your doctor will weigh the potential benefits against the potential risks. Consult your doctor before taking it.

Alcohol

Avoid consumption of alcohol while taking NIXIDE 100MG SUSPENSION.

Kidney

NIXIDE 100MG SUSPENSION should be used with caution in patients with kidney problems as safety data has not been established yet. Consult your doctor before taking it.

Liver

NIXIDE 100MG SUSPENSION should be taken with caution in patients with liver problems as safety data has not been established yet. Consult your doctor before taking it.

Allergy

Do not take NIXIDE 100MG SUSPENSION if you are allergic to Nitazoxanide or any of the other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Before taking NIXIDE 100MG SUSPENSION, inform your doctor if you are taking any of the following medicine:

• medicines used to manage or manage blood clots (Ex. warfarin)

Overdosage:

If you or anyone else accidentally took more of NIXIDE 100MG SUSPENSION, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep NIXIDE 100MG SUSPENSION out of reach of children
• Store at room temperature

FAQs About NIXIDE 100MG SUSPENSION

What is NIXIDE 100MG SUSPENSION used for?

NIXIDE 100MG SUSPENSION is used to manage diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.

Can NIXIDE 100MG SUSPENSION cause headaches?

Yes. Headache is one of the most common side effects of taking NIXIDE 100MG SUSPENSION. In case your child is experiencing a headache after taking NIXIDE 100MG SUSPENSION, rest and relax. Keep hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of a. If the symptoms do not improve please consult your doctor.

What precaution is to be taken before taking NIXIDE 100MG SUSPENSION?

NIXIDE 100MG SUSPENSION should be used with caution in lactating and in children below 1 year of age. NIXIDE 100MG SUSPENSION should be used with caution in patients who have renal problems, hepatic problems, pregnant women, and elderly patients. Please consult your doctor before taking NIXIDE 100MG SUSPENSION.

Does NIXIDE 100MG SUSPENSION change urine colour?

Yes, NIXIDE 100MG SUSPENSION may change the colour of urine. This is normal and not harmful. if symptoms do not improve or get worse consult your doctor immediately.

How does NIXIDE 100MG SUSPENSION work?

NIXIDE 100MG SUSPENSION works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa causing diarrhoea. 

References

1. KD. Tripathi. Antiamoebic and Other Antiprotozoal Drugs. Drugs Essentials of medical pharmacology. Seventh edition. 2013. Page – 840-841.

2. Mohammad Rashidul Hashan, Khaled Mosaad Elhusseiny, Le Huu-Hoaiz, Thuan Minh Tieu , Soon Khai Low et.al. Effect of nitazoxanide on diarrhea: A systematic review and network meta-analysis of randomized controlled trials. Journal of Acta Tropica. Science direct. October 2020 [Accessed on 10th August 2022] https://www.sciencedirect.com/science/article/abs/pii/S0001706X19316328?via%3Dihub

3. Samarendra Mahapatro, Nijwm Mahilary, Amit Kumar Satapathy, and Rashmi Ranjan Das. Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country. NIH. National Library of Medicine, National Center for Biotechnology information. Pubmed Central. February 2017 [Accessed on 10th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346365/

4. Romark Pharmaceuticals. US Food and Drug Administration. [Revised in June 2005] [Accessed on 10th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021818lbl.pdf

5. Romark Pharmaceuticals. ALINIA Tablets and Oral suspension. [Revised in April 2017] [Accessed on 10th August 2022] https://www.alinia.com/wp-content/uploads/2017/08/prescribing-information.pdf

6. Nitazoxanide. Mayoclinic. [Revised in November 2022] [Accessed on 10th August 2022] Nitazoxanide (Oral Route) Proper Use - Mayo Clinic

Useful Diagnostic Tests

• Stool Examination

Author Details

Written By Dr. Shruthi M R - BDS

Reviewed For Accuracy By Dr. Nitin Sattiwale - MBBS

Last updated on 13 Jan 2023 | 05:06 PM(IST)