Glenmark Pharmaceuticals Ltd

Nitazet Suspension 30ml

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Introduction About NITAZET SUSPENSION

NITAZET SUSPENSION contains Nitazoxanide which belongs to the group of medicines called Antiprotozoals. It is used to manage diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.

Avoid consumption of alcohol while taking this medicine. NITAZET SUSPENSION is not effective for the management of diarrhoea caused by C. parvum in HIV-infected or immunodeficient patients. Before taking NITAZET SUSPENSION, inform your doctor if you have diabetes, kidney, liver, biliary problems.

NITAZET SUSPENSION should be used with caution among pregnant women and breastfeeding women as safety data has not been established yet. Safety and effectiveness of NITAZET SUSPENSION in children below 1 year of age has not been established yet. It should be used with caution in elderly patients above 65 years of age.

The most common side effects of taking NITAZET SUSPENSION are abdominal pain, diarrhoea, headache, and nausea. Contact your doctor if any of the above symptoms worsen.

Uses Of NITAZET SUSPENSION

  • to manage diarrhea caused by Giardia lamblia or Cryptosporidium parvum

How NITAZET SUSPENSION Works

NITAZET SUSPENSION works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa causing diarrhoea.

How to use NITAZET SUSPENSION

Take NITAZET SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Side Effects Of NITAZET SUSPENSION

Common

  • abdominal pain
  • diarrhea
  • headache
  • nausea

How To Manage Side Effects

Headache: 

Rest and relax. Keep yourself hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of alcohol. If the symptom does not improve, contact your physician for advice.

Nausea:

Stick to simple meals. Avoid eating oil-rich or spicy foods. If the symptom does not improve, contact your physician for advice.

Diarrhoea:

Drink more fluids like water or fruit juice to keep yourself hydrated. Do not take any medicine on your own for diarrhoea without consulting your physician. If the symptom does not improve, contact your physician for advice.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have lesser and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your physician for advice.

Warning & Precautions

Pregnancy

NITAZET SUSPENSION should be used with caution in pregnant women or women planning to have a baby as safety data has not been established yet. Consult your doctor before taking it.

Breastfeeding

NITAZET SUSPENSION should be used with caution in breastfeeding women as it is not known if it is excreted in breastmilk. Your doctor will weigh the potential benefits against the potential risks. Consult your doctor before taking it.

Alcohol

Avoid consumption of alcohol while taking NITAZET SUSPENSION.

Kidney

NITAZET SUSPENSION should be used with caution in patients with kidney problems as safety data has not been established yet. Consult your doctor before taking it.

Liver

NITAZET SUSPENSION should be taken with caution in patients with liver problems as safety data has not been established yet. Consult your doctor before taking it.

Allergy

Do not take NITAZET SUSPENSION if you are allergic to Nitazoxanide or any of the other ingredients of this medicine.

Others

NITAZET SUSPENSION is not recommended for use if you:

  • have diarrhoea caused by C. parvum in HIV-infected or immunodeficient patients

Before taking NITAZET SUSPENSION inform your doctor if you:

  • have biliary problems

Use in pediatrics:

Safety and effectiveness of NITAZET SUSPENSION in children below 1 year of age has not been established yet. Consult your doctor before taking it.

Use in geriatrics:

NITAZET SUSPENSION should be used with caution in elderly patients 65 years and above. Consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking NITAZET SUSPENSION, inform your doctor if you are taking any of the following medicine:

  • medicines used to manage or manage blood clots (Ex. warfarin)

Overdosage:

If you or anyone else accidentally took more of NITAZET SUSPENSION, consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug :   Nitazoxanide
Pharmacological Category :   Antiprotozoals
Therapeutic Indication :   Diarrhoea
Dosage Forms :   Tablet, Oral Suspension, Suspension, Syrup, Dispersible

More Information

  • Keep NITAZET SUSPENSION out of reach of children
  • Store at room temperature

FAQs About NITAZET SUSPENSION

What is NITAZET SUSPENSION used for?

NITAZET SUSPENSION is used to manage diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.

Can NITAZET SUSPENSION cause headaches?

Yes. Headache is one of the most common side effects of taking NITAZET SUSPENSION. In case your child is experiencing a headache after taking NITAZET SUSPENSION, rest and relax. Keep hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of a. If the symptoms do not improve please consult your doctor.

What precaution is to be taken before taking NITAZET SUSPENSION?

NITAZET SUSPENSION should be used with caution in lactating and in children below 1 year of age. NITAZET SUSPENSION should be used with caution in patients who have renal problems, hepatic problems, pregnant women, and elderly patients. Please consult your doctor before taking NITAZET SUSPENSION.

Does NITAZET SUSPENSION change urine colour?

Yes, NITAZET SUSPENSION may change the colour of urine. This is normal and not harmful. if symptoms do not improve or get worse consult your doctor immediately.

How does NITAZET SUSPENSION work?

NITAZET SUSPENSION works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa causing diarrhoea. 

References

1. KD. Tripathi. Antiamoebic and Other Antiprotozoal Drugs. Drugs Essentials of medical pharmacology. Seventh edition. 2013. Page – 840-841.

2. Mohammad Rashidul Hashan, Khaled Mosaad Elhusseiny, Le Huu-Hoaiz, Thuan Minh Tieu , Soon Khai Low et.al. Effect of nitazoxanide on diarrhea: A systematic review and network meta-analysis of randomized controlled trials. Journal of Acta Tropica. Science direct. October 2020 [Accessed on 10th August 2022] https://www.sciencedirect.com/science/article/abs/pii/S0001706X19316328?via%3Dihub

3. Samarendra Mahapatro, Nijwm Mahilary, Amit Kumar Satapathy, and Rashmi Ranjan Das. Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country. NIH. National Library of Medicine, National Center for Biotechnology information. Pubmed Central. February 2017 [Accessed on 10th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346365/

4. Romark Pharmaceuticals. US Food and Drug Administration. [Revised in June 2005] [Accessed on 10th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021818lbl.pdf

5. Romark Pharmaceuticals. ALINIA Tablets and Oral suspension. [Revised in April 2017] [Accessed on 10th August 2022] https://www.alinia.com/wp-content/uploads/2017/08/prescribing-information.pdf

6. Nitazoxanide. Mayoclinic. [Revised in November 2022] [Accessed on 10th August 2022] Nitazoxanide (Oral Route) Proper Use - Mayo Clinic

Useful Diagnostic Tests

  • Stool Examination

Author Details

Written By Dr. Shruthi M R - BDS
Reviewed For Accuracy By Dr. Nitin Sattiwale - MBBS
Last updated on 13 Jan 2023 | 05:06 PM(IST)
Lab updated