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Introduction About NITARID SYRUP
NITARID SYRUP contains Nitazoxanide which belongs to the group of medicines called Antiprotozoals. It is used to manage diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.
Avoid consumption of alcohol while taking this medicine. NITARID SYRUP is not effective for the management of diarrhoea caused by C. parvum in HIV-infected or immunodeficient patients. Before taking NITARID SYRUP, inform your doctor if you have diabetes, kidney, liver, biliary problems.
NITARID SYRUP should be used with caution among pregnant women and breastfeeding women as safety data has not been established yet. Safety and effectiveness of NITARID SYRUP in children below 1 year of age has not been established yet. It should be used with caution in elderly patients above 65 years of age.
The most common side effects of taking NITARID SYRUP are abdominal pain, diarrhoea, headache, and nausea. Contact your doctor if any of the above symptoms worsen.
Uses Of NITARID SYRUP
- to manage diarrhea caused by Giardia lamblia or Cryptosporidium parvum
How NITARID SYRUP Works
NITARID SYRUP works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa causing diarrhoea.
How to use NITARID SYRUP
Take NITARID SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Side Effects Of NITARID SYRUP
Common
- abdominal pain
- diarrhea
- headache
- nausea
How To Manage Side Effects
Headache:
Rest and relax. Keep yourself hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of alcohol. If the symptom does not improve, contact your physician for advice.
Nausea:
Stick to simple meals. Avoid eating oil-rich or spicy foods. If the symptom does not improve, contact your physician for advice.
Diarrhoea:
Drink more fluids like water or fruit juice to keep yourself hydrated. Do not take any medicine on your own for diarrhoea without consulting your physician. If the symptom does not improve, contact your physician for advice.
Stomach pain:
Rest and relax. Eat and drink slowly or try to have lesser and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your physician for advice.
Warning & Precautions
Pregnancy
NITARID SYRUP should be used with caution in pregnant women or women planning to have a baby as safety data has not been established yet. Consult your doctor before taking it.
Breastfeeding
NITARID SYRUP should be used with caution in breastfeeding women as it is not known if it is excreted in breastmilk. Your doctor will weigh the potential benefits against the potential risks. Consult your doctor before taking it.
Alcohol
Avoid consumption of alcohol while taking NITARID SYRUP.
Kidney
NITARID SYRUP should be used with caution in patients with kidney problems as safety data has not been established yet. Consult your doctor before taking it.
Liver
NITARID SYRUP should be taken with caution in patients with liver problems as safety data has not been established yet. Consult your doctor before taking it.
Allergy
Do not take NITARID SYRUP if you are allergic to Nitazoxanide or any of the other ingredients of this medicine.
Others
NITARID SYRUP is not recommended for use if you:
- have diarrhoea caused by C. parvum in HIV-infected or immunodeficient patients
Before taking NITARID SYRUP inform your doctor if you:
- have biliary problems
Use in pediatrics:
Safety and effectiveness of NITARID SYRUP in children below 1 year of age has not been established yet. Consult your doctor before taking it.
Use in geriatrics:
NITARID SYRUP should be used with caution in elderly patients 65 years and above. Consult your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking NITARID SYRUP, inform your doctor if you are taking any of the following medicine:
- medicines used to manage or manage blood clots (Ex. warfarin)
Overdosage:
If you or anyone else accidentally took more of NITARID SYRUP, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Nitazoxanide |
| Pharmacological Category | : | Antiprotozoals |
| Therapeutic Indication | : | Diarrhoea |
| Dosage Forms | : | Tablet, Oral Suspension, Suspension, Syrup, Dispersible |
More Information
- Keep NITARID SYRUP out of reach of children
- Store at room temperature
FAQs About NITARID SYRUP
What is NITARID SYRUP used for?
NITARID SYRUP is used to manage diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.
Can NITARID SYRUP cause headaches?
Yes. Headache is one of the most common side effects of taking NITARID SYRUP. In case your child is experiencing a headache after taking NITARID SYRUP, rest and relax. Keep hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of a. If the symptoms do not improve please consult your doctor.
What precaution is to be taken before taking NITARID SYRUP?
NITARID SYRUP should be used with caution in lactating and in children below 1 year of age. NITARID SYRUP should be used with caution in patients who have renal problems, hepatic problems, pregnant women, and elderly patients. Please consult your doctor before taking NITARID SYRUP.
Does NITARID SYRUP change urine colour?
Yes, NITARID SYRUP may change the colour of urine. This is normal and not harmful. if symptoms do not improve or get worse consult your doctor immediately.
How does NITARID SYRUP work?
NITARID SYRUP works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa causing diarrhoea.
References
1. KD. Tripathi. Antiamoebic and Other Antiprotozoal Drugs. Drugs Essentials of medical pharmacology. Seventh edition. 2013. Page – 840-841.
2. Mohammad Rashidul Hashan, Khaled Mosaad Elhusseiny, Le Huu-Hoaiz, Thuan Minh Tieu , Soon Khai Low et.al. Effect of nitazoxanide on diarrhea: A systematic review and network meta-analysis of randomized controlled trials. Journal of Acta Tropica. Science direct. October 2020 [Accessed on 10th August 2022] https://www.sciencedirect.com/science/article/abs/pii/S0001706X19316328?via%3Dihub
3. Samarendra Mahapatro, Nijwm Mahilary, Amit Kumar Satapathy, and Rashmi Ranjan Das. Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country. NIH. National Library of Medicine, National Center for Biotechnology information. Pubmed Central. February 2017 [Accessed on 10th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346365/
4. Romark Pharmaceuticals. US Food and Drug Administration. [Revised in June 2005] [Accessed on 10th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021818lbl.pdf
5. Romark Pharmaceuticals. ALINIA Tablets and Oral suspension. [Revised in April 2017] [Accessed on 10th August 2022] https://www.alinia.com/wp-content/uploads/2017/08/prescribing-information.pdf
6. Nitazoxanide. Mayoclinic. [Revised in November 2022] [Accessed on 10th August 2022] Nitazoxanide (Oral Route) Proper Use - Mayo Clinic
Useful Diagnostic Tests
- Stool Examination
Author Details
