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Key Composition
NICIP PLUS TABLET is a combination of Nimesulide and Paracetamol, which belongs to the group of medicines called Non-steroidal Anti-inflammatory drugs. NICIP PLUS TABLET is used to provide relief from inflammation and pain in conditions such as headache, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, and/or painful menses in affected individuals.
NICIP PLUS TABLET is not recommended for use in patients allergic to nimesulide, paracetamol, and/or other NSAIDS. It is also not recommended for use in patients with peptic ulcers, gastrointestinal bleeding, severe liver disease, and/or severe kidney disease.
Before taking NICIP PLUS TABLET, inform your doctor if you are alcohol dependent and/or have other kidney problems and/or heart problems such as heart failure.
NICIP PLUS TABLET is not recommended for use during pregnancy and in breastfeeding women. It is also not recommended for use in children (aged below 12 years). NICIP PLUS TABLET should be used with caution in elderly patients (aged above 65 years) after consulting the doctor.
The most common side effects of NICIP PLUS TABLET are dizziness, excess sleepiness, stomach upset, nausea, abdominal discomfort, diarrhea, and/or peripheral oedema (swelling in legs or arms). Consult your doctor if any of the symptoms worsen.
Uses Of NICIP PLUS TABLET
- Provides relief from inflammation and pain in conditions (such as headache, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, and/or painful menses) in affected individuals.
How NICIP PLUS TABLET Works
NICIP PLUS TABLET provides relief from pain and inflammation, where nimesulide and paracetamol act by blocking the action of prostaglandin (chemical messengers responsible for pain and inflammation), resulting in reduced inflammation and providing relief from pain in affected individuals.
How to use NICIP PLUS TABLET
Take NICIP PLUS TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects Of NICIP PLUS TABLET
Common
- Dizziness, excess sleepiness
- Stomach upset, nausea, abdominal discomfort, diarrhea
- Peripheral oedema (swelling in legs/arms)
- Signs of hypersensitivity reactions such as skin rash, red itchy welts, itching, and shortness of breath
Rare
Stop taking NICIP PLUS TABLET and contact your doctor immediately if you experience any of the following side effects:
- Signs of severe allergic reactions such as skin rash, itching, swelling of the mouth/face, and/or shortness of breath
- Skin rash/peeling, mouth ulcers
- Breathing problems, unexplained bruising/bleeding
- Signs of impaired liver function such as nausea, sudden weight loss, loss of appetite, and yellowing of the eyes and skin
How To Manage Side Effects
Diarrhea
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor if the diarrhea does not improve.
Dizziness Or Drowsiness
Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult your doctor if the dizziness worsens.
Nausea And Vomiting
Try to take NICIP PLUS TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the nausea and vomiting get worse.
Warning & Precautions
Pregnancy
ContraindicatedNICIP PLUS TABLET is not recommended for use during pregnancy. Consult your doctor before taking NICIP PLUS TABLET.
Breastfeeding
ContraindicatedNICIP PLUS TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking NICIP PLUS TABLET.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy, drowsy, and/or sleepy after taking NICIP PLUS TABLET.
Alcohol
ContraindicatedAvoid consumption of alcohol while taking NICIP PLUS TABLET because it might cause liver damage.
Kidney
Consult your doctorNICIP PLUS TABLET is not recommended for use in patients with severe kidney disease and/or analgesic nephropathy. It should be used with caution in patients with other kidney problems. Consult your doctor before taking NICIP PLUS TABLET.
Liver
ContraindicatedNICIP PLUS TABLET is not recommended in patients with liver disease. Consult your doctor before taking NICIP PLUS TABLET.
Allergy
ContraindicatedDo not take NICIP PLUS TABLET if you are allergic to nimesulide, paracetamol, other NSAIDS, and/or other ingredients of this medicine.
Heart Disease
Use with CautionNICIP PLUS TABLET should be used with caution in patients with heart failure. Consult your doctor before taking NICIP PLUS TABLET.
Use In Pediatrics
ContraindicatedNICIP PLUS TABLET is not recommended for use in children (aged below 12 years). Consult your doctor before administering the medicine to the child.
Use In Geriatrics
Use with CautionNICIP PLUS TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking NICIP PLUS TABLET.
Others
NICIP PLUS TABLET is not recommended for use if you:
- Have peptic ulcers and/or gastrointestinal bleeding
Before taking NICIP PLUS TABLET, inform your doctor if you:
- Are alcohol dependent
Interactions
A. Drug-drug interactions:
Before taking NICIP PLUS TABLET, inform your doctor if you are taking any of the following medicine:
- Anticoagulants (medicines used to manage blood clotting) Ex. warfarin
- Cholestyramine (medicine used to lower high cholesterol levels)
- Metoclopramide, domperidone (medicines used to manage nausea and vomiting)
B. Drug-food interaction:
Avoid consumption of foods containing caffeine and/or drinks such as tea, chocolate, and coffee since it leads to excessive dizziness and sleepiness.
Overdosage:
If you or anyone else accidentally took more of NICIP PLUS TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Nimesulide, Paracetamol |
| Pharmacological Category | : | Non-steroidal Anti-inflammatory drugs |
| Therapeutic Indication | : |
Osteoarthritic pain, Fever, Dysmenorrhea |
| Dosage Forms | : | Tablet, Capsule, Suspension |
More Information
Storage
- Keep NICIP PLUS TABLET out of reach of children
- Store NICIP PLUS TABLET in a cool, dry place
FAQs About NICIP PLUS TABLET
Q: What is Nicip Plus Tablet used for?
A: Nicip Plus Tablet is used for pain relief, headache, muscle pain, dental pain, joint pain, back pain, menstrual pain, sprains, strains, sports injuries, and other forms of painful conditions.
Q: When can I notice pain relief after using Nicip Plus Tablet?
A: You may notice that your pain subsides within 1 hour of using Nicip Plus Tablet. It may take a day to show significant effects, although this can vary from person to person.
Q: How long does it take for Nicip Plus Tablet to show its effects?
A: Relief from pain may occur within an hour of taking Nicip Plus Tablet. Significant effects may take up to a day depending on individual health conditions.
Q: Is Nicip Plus Tablet a good painkiller?
A: Nicip Plus Tablet is commonly used as a painkiller and is generally considered effective for relieving various types of pain. It contains nimesulide and paracetamol, which work together to reduce pain and inflammation.
Q: Does Nicip Plus Tablet contain paracetamol?
A: Yes. Nicip Plus Tablet is a combination of paracetamol and nimesulide, which collectively work together for alleviating pain and inflammation.
Q: Is Nicip Plus Tablet used for fever?
A: Although it contains paracetamol, Nicip Plus Tablet is mainly used to relieve pain and inflammation. It may help control very mild fever and body pain in certain situations.
Q: Is Nicip Plus Tablet good for stomach pain?
A: No. Nicip Plus Tablet should not be taken for stomach pain as it may increase stomach acid secretion and worsen the condition.
Q: Can I consume two tablets of Nicip Plus Tablet together for faster pain relief?
A: Nicip Plus Tablet is usually prescribed as one tablet 2–3 times daily. Taking two tablets together may lead to overdose and unwanted side effects.
Q: Can I use Nicip Plus Tablet for long-term?
A: Nicip Plus Tablet is generally prescribed for short-term pain management. Long-term use without medical supervision may severely affect liver health.
Q: What are the long-term side effects of using Nicip Plus Tablet?
A: Long-term use of Nicip Plus Tablet may increase the risk of liver damage. These risks can often be minimized when used as advised by a doctor.
Q: Can I take Nicip Plus Tablet daily?
A: Nicip Plus Tablet can be taken daily if recommended by your doctor, usually for a short period and generally not exceeding four weeks.
Q: Does Nicip Plus Tablet damage your liver?
A: Prolonged use or overdose of Nicip Plus Tablet has been associated with liver damage. Use it only for the duration prescribed by your doctor.
Q: Is Nicip Plus Tablet banned for use in children?
A: Nicip Plus Tablet is not recommended for children below 12 years of age. Consult a doctor for appropriate alternatives.
Q: Does Nicip Plus Tablet have side effects?
A: Common side effects include dizziness, sleepiness, stomach upset, nausea, abdominal discomfort, diarrhea, and swelling of the arms or legs.
Q: Can Nicip Plus Tablet be used in pregnant women?
A: Consult your doctor before taking Nicip Plus Tablet during pregnancy, as its effects on an unborn baby are not fully known.
Q: Can I consume alcohol while taking Nicip Plus Tablet?
A: Alcohol should be avoided while taking Nicip Plus Tablet because it may increase the risk of liver damage.
Q: What precautions must be taken while using Nicip Plus Tablet?
A: Inform your doctor if you have kidney problems, heart failure, or alcohol dependence before using Nicip Plus Tablet.
Q: Who should not take Nicip Plus Tablet?
A: People allergic to nimesulide, paracetamol, or other NSAIDs, and those with severe kidney disease, liver disease, peptic ulcers, or gastrointestinal bleeding should avoid it.
Q: Is Nicip Plus Tablet safe for kids?
A: Nicip Plus Tablet is not recommended for children under 12 years of age. Consult your doctor before administering it to a child.
References
1. KD Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic analgesics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 203,206.
2. Cristina Monteiro, Beatriz Dias, and Maria Vaz-Patto. Headache as an Adverse Reaction to the Use of Medication in the Elderly: A Pharmacovigilance Study. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. March 2021. [Accessed on 10th August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967518/
3. Crescent Pharma Limited. Electronic Medicines Compendium (EMC) [Revised in October 2021] [Accessed on 10th August 2024] https://www.medicines.org.uk/emc/files/pil.14044.pdf
4. Leeford Healthcare Limited. Nedolide-P. [Accessed on 10th August 2024] https://www.leeford.in/product/1046/nedolide-p
5. Orlife Healthcare Pvt. Ltd. Orflam-P. [Accessed on 10th August 2024] https://www.orlifehealthcare.com/product/orflam-p/
6. P&B Pharmaceuticals Ltd. Algiril tablet. [Accessed on 10th August 2024] http://www.pbpharma.co.in/algiril_tab.html
7. Pharmatech Healthcare. DIPLONIM-P Tab. [Accessed on 10th August 2024] http://www.pharmatechworld.com/product_division.php?page=2&id=2
8. Medlock Healthcare NICLOC-P. [Accessed on 10th August 2024] https://www.medlockhealthcare.in/product/nimesulide-100mg-paracetamol-325mg-
9. Nilrise Pharmaceuticals Pvt. Ltd. Zoynim-P Tablet. [Accessed on 10th August 2024] https://www.nilrisepharma.com/product/zoynim-p-tablet
10. Apikos Pharma. ORNIMOL-N. [Accessed on 10th August 2024] https://www.apikospharma.com/product/ornimol-n/
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- Healthy Midlife Checkup
- Men Health Checkup - Advanced
- Complete Women Checkup
- Full Body Checkup - Gold
- Full Body Checkup – Silver
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