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Introduction About NICARDIA RETARD 20MG TABLET
Nicardia Retard 20mg Tablet is a prescription medication primarily used to manage hypertension (high blood pressure) and other cardiovascular conditions. It belongs to a class of drugs called calcium channel blockers that help relax and widen blood vessels, making it easier for the heart to pump blood.
Nicardia Retard 20mg Tablet may be prescribed either on its own or in combination with other medications. Your doctor will determine the appropriate dosage and frequency based on your condition, ensuring you receive the correct amount to manage your condition. The dosage may be adjusted by your doctor depending on your response to the medication and your blood pressure levels. You can take the medication at any time of day, with or without food, but it is best to take it at the same time every day. Ensure you take it as soon as you remove it from the package, as it is sensitive to light and may lose its effectiveness if left outside the pack for too long.
Continue taking this medication for the full duration recommended by your doctor, even if you feel fine. Do not stop it on your own, as high blood pressure often shows no symptoms, and discontinuing the medicine could worsen your condition. Staying active through regular exercise, losing weight, and maintaining a healthy diet will also assist in managing your blood pressure. Always follow your doctor's guidance while using this medication.
Common side effect of this medication includes dizziness, headaches, swelling of the ankles, fatigue, unusual heartbeat (palpitations), flushing and constipation. If any of these symptom’s trouble you or persist, consult your doctor.
Before taking this medicine, inform your doctor if you have any heart, liver, or kidney problems. If you are pregnant or breastfeeding, consult your doctor for guidance before taking it. Also, make sure to tell your doctor about any other medications you are using, particularly those for high blood pressure or heart conditions. Limit alcohol consumption while on this medication, as it may lower your blood pressure and cause dizziness or lightheadedness. It is important to have your blood pressure monitored regularly to ensure the medication is working effectively.
Uses Of NICARDIA RETARD 20MG TABLET
- Hypertension (high blood pressure)
- Other cardiovascular conditions
Benefits of NICARDIA RETARD 20MG TABLET
- Manages Hypertension: Helps reduce high blood pressure, decreasing the risk of heart attack and stroke.
- Improves Heart Function: Aids in the treatment of angina (chest pain) and other heart-related conditions.
- Long-Lasting Effect: The slow-release formulation ensures sustained effectiveness throughout the day, requiring fewer doses.
- Improves Blood Circulation: Promotes better circulation by relaxing the blood vessels.
How NICARDIA RETARD 20MG TABLET Works
Nicardia Retard 20mg tablet, containing nifedipine that works by relaxing and widening the blood vessels, which helps to improve blood flow. It is a calcium channel blocker that inhibits the entry of calcium into the smooth muscle cells of the heart and blood vessel walls. This reduces the contraction of the blood vessels, lowering blood pressure and improving oxygen supply to the heart. Nicardia is commonly used to manage conditions like hypertension (high blood pressure) and angina (chest pain). By reducing the strain on the heart, it helps to reduce complications such as heart attacks and strokes.
How to use NICARDIA RETARD 20MG TABLET
Follow your doctor's instructions regarding the exact dosage. Do not exceed the recommended daily dosage.
How to Take Nicardia Retard 20mg Tablet?
- Take one tablet daily with food to minimize potential stomach upset
- Swallow the tablet whole with a glass of water. Do not crush or chew the medication.
- For best results, take the tablet at the same time each day.
What if I forgot to take NICARDIA RETARD 20MG TABLET
- If you forget to take your dose, take it as soon as you remember.
- Do not take two doses to make up for a missed dose. This could increase your risk of side effects.
- If it is almost time for your next dose, skip the missed dose and take your regular dose at the usual time.
Side Effects Of NICARDIA RETARD 20MG TABLET
Like all medicines, Nicardia Retard may cause certain side effects in some individuals, although not everybody gets them.
The most common side effects of taking Nicardia Retard 20mg Tablet are:
- Dizziness
- Headaches
- Swelling of the ankles
- Fatigue
- Unusual heartbeat (palpitations)
- Flushing
- Constipation
When to consult your doctor?
- Severe allergic reactions symptoms such as rash, itching or swelling, especially of the face/tongue/throat, severe dizziness or trouble breathing
- Heart attack or arrhythmia symptoms such as chest pain or irregular heartbeat
- Severe dizziness or fainting
- Kidney problems symptoms such as swelling of the legs or ankles
- Respiratory symptoms such as shortness of breath or difficulty breathing
- Severe or persistent headache
- Unusual fatigue or weakness
- Liver problems symptoms such as yellowing of the skin or eyes (jaundice)
How To Manage Side Effects
Dizziness Or Drowsiness
- Sit or Lie Down: If you feel dizzy, sit down or lie down immediately to prevent falling. Keep your head still and close your eyes if needed.
- Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
- Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
- Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
- Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.
Headache
- Rest in a Quiet, Dark Room: Find a calm, quiet space away from bright lights and loud noises. Lie down and close your eyes.
- Hydrate: Dehydration can contribute to headaches, so drink plenty of water.
- Apply a Cold or Warm Compress: A cold pack on your forehead may reduce pain, or a warm compress on your neck or shoulders can relieve tension.
- Over-the-Counter Pain Relief: You can take over-the-counter pain relievers like acetaminophen or ibuprofen if appropriate for you. Follow the recommended dosage.
- Practice Relaxation Techniques: Deep breathing exercises, meditation, or gentle stretching can help reduce stress and alleviate headache symptoms.
Warning & Precautions
Pregnancy
ContraindicatedNicardia Retard 20mg tablet is not recommended for use in pregnant women. It is important to consult your doctor before taking this medication.
Breastfeeding
ContraindicatedNicardia Retard 20mg tablet is not recommended for use in breast-feeding women. It is important to consult your doctor before taking this medication.
Driving and Using Machines
Use with CautionDo not drive or operate machines if you experience dizziness or sleepiness or extremely tiredness or visual disturbances.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking Nicardia Retard as it may cause dizziness or fainting.
Kidney
Use with CautionNicardia Retard should be used with caution in patients with kidney problems. Consult your doctor before taking it.
Liver
Use with CautionNicardia Retard should be used with caution in patients with liver problems. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take this medication if you are allergic to nifedipine or any other ingredients of this medicine.
Heart Disease
Consult your doctorNicardia Retard 20mg tablet is not recommended for use in patients who had a heart attack, unstable angina, sudden angina attack, aortic stenosis (narrowing of the aortic valve) and collapsed because of heart problems (cardiogenic shock) and should be taken with caution in patients having poor cardiac reserve (the heart cannot cope with increased strain). Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedNicardia Retard 20mg tablet is not recommended for use in children and adolescents (aged below 18 years). Consult your pediatrician before giving it.
Use In Geriatrics
Use with CautionNicardia Retard 20mg tablet should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking it.
Other Warnings for NICARDIA RETARD 20MG TABLET
Before taking Nicardia Retard 20mg tablet, inform your doctor if you have:
- low blood pressure
- diabetic
Who should not take [GBNKEYWORD
Nicardia Retard 20mg tablet is not recommended for use if you have:
- inflammation of the bowel or intestines, such as Crohn’s disease
- obstruction or narrowing of intestines
- obstruction in the oesophagus (the tube connecting the throat to the stomach)
- Kock pouch (a surgically constructed intestinal reservoir with an opening through the abdominal wall) in your gut
- malignant hypertension (continuous rise in blood pressure despite management)
Safety Advice
- Follow your doctor's instructions regarding the exact dosage.
- Do not exceed the recommended daily dosage.
- Take one tablet daily with food to minimize potential stomach upset
- Swallow the tablet whole with a glass of water. Do not crush or chew the medication.
- For best results, take the tablet at the same time each day.
- Let your doctor know if you have kidney problems or liver problems
- Let your doctor know If you are pregnant or planning to become pregnant or breastfeeding women.
- Make sure to inform your doctor about all the medications you are currently taking, including any over-the-counter drugs, as some of them may interact with Nifedipine.
- Grapefruit and grapefruit juice may interact with Nifedipine, increasing the risk of side effects such as dangerously low blood pressure. It is recommended to avoid consuming grapefruit while undergoing management.
- It is best to avoid alcohol, as it can heighten the risk of side effects such as dizziness or fainting.
- Do not abruptly stop taking Nicardia Retard, as this could cause a rapid rise in blood pressure or trigger angina. It is advised to gradually reduce the dosage under medical supervision if you need to discontinue the medication.
- Inform your doctor if you have any heart conditions, particularly aortic stenosis, or if you are taking other heart medications, as these may impact how Nifedipine works.
Diet and Lifestyle Advice
01. What are some general lifestyle recommendations, including healthy eating, exercise, and stress management, that can support heart health while taking Nicardia Retard?
|
Lifestyle Area |
Tip |
Details/Recommendation |
|
Healthy Eating |
Adopt a heart-healthy diet |
Include plenty of fruits, vegetables, whole grains, lean proteins (chicken, fish, tofu), and healthy fats (olive oil, avocado). Limit saturated fats, processed foods, and sugars. |
|
Reduce sodium intake |
Aim for less than 2,300 mg of sodium per day, or 1,500 mg if you have high blood pressure, as excessive salt can increase strain on your heart. |
|
|
Increase potassium intake |
Potassium-rich foods (e.g., bananas, potatoes, spinach, and beans) help counteract the effects of sodium and support healthy blood pressure. |
|
|
Exercise |
Engage in regular aerobic exercise |
Aim for at least 150 minutes of moderate-intensity aerobic exercise (like walking, cycling, or swimming) per week to improve cardiovascular fitness and lower blood pressure. |
|
Include strength training |
Add strength training exercises 2-3 times a week to improve muscle health and metabolism. |
|
|
Be active throughout the day |
Incorporate walking or light physical activity into your daily routine, such as taking the stairs or walking for short errands, to keep your circulation healthy. |
|
|
Stress Management |
Practice relaxation techniques |
Try stress-relieving activities like yoga, deep breathing exercises, meditation, or mindfulness to lower stress, which can positively impact heart health. |
|
Get adequate sleep |
Aim for 7-9 hours of quality sleep per night to support overall health, including heart health. Poor sleep can negatively affect blood pressure and heart function. |
|
|
Stay socially connected |
Strong social connections can help reduce stress and improve mental well-being, contributing to better heart health. |
|
|
Monitoring Health |
Regular health check-ups |
Regular doctor visits help monitor the effectiveness of Nicardia Retard and any potential side effects, as well as keeping an eye on blood pressure and cholesterol levels. |
|
Track your blood pressure |
Use a home blood pressure monitor to track your levels, and share the readings with your healthcare provider to adjust your treatment plan if needed. |
Drug - Drug interaction
Inform your physician if you are taking any of the following medicine before taking Nicardia Retard 20mg tablet:
1.Antihypertensive Drugs (other blood pressure medications)
- Interaction: Nifedipine may enhance the blood pressure-lowering effect of other antihypertensive drugs (e.g., ACE inhibitors, beta-blockers, diuretics).
- Effect: This could lead to an excessive drop in blood pressure, causing symptoms like dizziness, fainting, or weakness.
- Management: Close monitoring of blood pressure is advised, and dosage adjustments may be needed for the antihypertensive drugs.
2.Cimetidine (H2-receptor antagonists)
- Interaction: Cimetidine may increase the levels of Nifedipine in the blood by slowing its metabolism.
- Effect: Increased Nifedipine levels can lead to an increased risk of side effects, such as swelling, flushing, and hypotension.
- Management: It may be necessary to adjust the dose of Nicardia Retard or monitor for signs of excessive blood pressure lowering.
3.CYP3A4 Inhibitors (e.g., ketoconazole, ritonavir, clarithromycin)
- Interaction: These medications can increase the concentration of Nifedipine by inhibiting its breakdown.
- Effect: This could lead to excessive lowering of blood pressure, swelling, and other adverse effects.
- Management: A dosage adjustment of Nifedipine may be required. Regular monitoring of blood pressure and side effects is recommended.
4.Beta-blockers (e.g., propranolol, atenolol)
- Interaction: When used together, there is a potential for additive effects in lowering blood pressure or heart rate.
- Effect: May cause bradycardia (slowed heart rate) or hypotension (low blood pressure).
- Management: Blood pressure and heart rate should be closely monitored. Dose adjustments of either drug might be necessary.
5.Digoxin
- Interaction: Nifedipine may increase plasma levels of digoxin, potentially leading to digoxin toxicity.
- Effect: Symptoms of digoxin toxicity include nausea, vomiting, confusion, and arrhythmias (irregular heartbeats).
- Management: Digoxin levels should be monitored, and dosage adjustments may be needed.
6.Lithium
- Interaction: Nifedipine may increase lithium levels, raising the risk of lithium toxicity.
- Effect: Lithium toxicity can cause tremors, confusion, and renal damage.
- Management: Monitor lithium levels closely, and adjust the dosage accordingly.
7.Alcohol
- Interaction: Alcohol can amplify the blood pressure-lowering effects of Nifedipine.
- Effect: This can result in dizziness, lightheadedness, or fainting.
- Management: Limit alcohol intake, especially when starting treatment with Nifedipine or adjusting the dosage.
8.Cholesterol-Lowering Drugs (e.g., atorvastatin, simvastatin, rosuvastatin)
- Interaction: Nifedipine can interact with these drugs, particularly simvastatin, increasing the levels of statins in the blood.
- Effect: This may increase the risk of statin side effects such as muscle pain (myopathy) or even rhabdomyolysis (a serious condition where muscle tissue breaks down and releases harmful substances into the bloodstream).
- Management:
- Monitoring: Regular monitoring of liver function and muscle symptoms is recommended.
- Dose Adjustment: In some cases, adjusting the dose of the statin, especially simvastatin, may be necessary. Alternatively, using a different statin with a lower potential for interaction, such as atorvastatin, may be considered.
- Alternative treatments: In some instances, non-calcium-channel-blocking antihypertensive medications may be used if interactions are problematic.
Drug - Food interaction
Grapefruit and Grapefruit Juice
- Interactions: Grapefruit and grapefruit juice inhibit CYP3A4, which can increase the blood levels of Top Nicardia Retard (Nifedipine), intensifying its blood pressure-lowering effects.
- Effects: Increased risk of hypotension, dizziness, and heart palpitations.
- Management: Advise patients to avoid grapefruit and grapefruit juice while taking Top Nicardia Retard to prevent potential drug interactions.
Synopsis
| Drug | : | Nifedipine |
| Pharmacological Category | : | Calcium Channel Blockers |
| Therapeutic Indication | : | High Blood Pressure, Angina |
| Dosage Forms | : | Tablet, Capsule |
More Information
Storage
- Store Nicardia Retard 20mg Tablet at room temperature, typically between 20-25°C
- Keep this medication away from direct sunlight, heat sources, and humidity to maintain its effectiveness
- Store the medications in a safe location, out of reach of children and pets
- Never freeze Nicardia Retard 20mg Tablet, as freezing can damage the medication
FAQs About NICARDIA RETARD 20MG TABLET
Q: What is Nicardia Retard 20mg Tablet used for?
A: Nicardia Retard is used to manage high blood pressure (hypertension) and certain types of chest pain (angina).
Q: How does Nicardia Retard 20mg Tablet work?
A: It works by relaxing and widening blood vessels, making it easier for the heart to pump blood and reducing blood pressure.
Q: Can Nicardia Retard 20mg Tablet be used to manage chest pain?
A: Yes, it is commonly used to manage chest pain (angina) by improving blood flow to the heart.
Q: Is Nicardia Retard 20mg Tablet suitable for children and adolescents?
A: It is not typically recommended for children and adolescents unless specifically prescribed by a doctor.
Q: Can Nicardia Retard 20mg Tablet be taken long-term?
A: Yes, it can be used long-term under a doctor's supervision, especially for managing high blood pressure and angina.
Q: What happens if I accidentally take too much Nicardia Retard?
A: Taking too much can lead to low blood pressure, dizziness, or fainting. Seek medical attention immediately if this happens.
Q: How long does it take for Nicardia Retard to lower blood pressure?
A: It typically starts to lower blood pressure within a few hours of taking it, with effects lasting for up to 24 hours.
Q: Is Nicardia Retard a safe medication?
A: It is generally safe when taken as prescribed, but like any medication, it may cause side effects in some people.
Q: What are the common side effects of Nicardia Retard 20mg Tablet?
A: Common side effects include headache, dizziness, flushing, swelling of the feet or ankles, and low blood pressure. If you experience severe side effects such as fainting or irregular heartbeat, contact your doctor immediately.
Q: Can I take Nicardia Retard 20mg Tablet with other medications?
A: It may interact with other medications such as blood pressure medications or cholesterol drugs. so always inform your doctor about any other medicines you are taking.
Q: What is the recommended dosage of Nicardia Retard 20mg Tablet?
A: The usual recommended dosage of Nicardia Retard 20mg Tablet is one tablet daily, but the exact dosage should be prescribed by your doctor based on your medical condition.
Q: Is it safe to drink alcohol while taking Nicardia Retard 20mg Tablet?
A: Alcohol may increase the risk of side effects such as dizziness or low blood pressure. It is best to limit alcohol consumption while taking Nicardia Retard 20mg Tablet.
Q: Where can I buy Nicardia Retard 20mg Tablet online?
A: You can buy Nicardia Retard 20mg Tablet online at Netmeds. Just visit their website and search for the product, and you will find options to purchase it directly from there.
References
1. KD Tripathi. Antianginal and other anti-ischaemic drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page –592-597.
2. Morgan E Snider, Donald S Nuzum, and Angie Veverka. Long-acting nifedipine in the management of the hypertensive patient. National Library of Medicine, National center for biotechnology information. PubMed Central. December 2008. [Accessed 14th March 2025] 
3. M Witkowska , W Tracz, G Kubler, M Negrusz-Kawecka, M Hlawaty, M Olszowska, P Salamon. [Comparative study to assess the efficacy and adverse effects of amlodipine and nifedipine retard in patients with stable exertional angina and hypertension]. National Library of Medicine, National center for biotechnology information. PubMed Central. May 1997. [Accessed 14th March 2025] 
4. Morningside Healthcare Ltd. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed 14th March 2025]
5. Ltd Pharma- D. Electronic Medicines Compendium (EMC). [Revised in July 2016]. [Accessed 14th March 2025]
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