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Introduction About NICARDIA RETARD 10MG TABLET
Nicardia Retard 10mg Tablet contains Nifedipine, a calcium channel blocker that supports smooth blood flow by relaxing blood vessels. It is often used for individuals with high blood pressure (hypertension) or certain heart-related concerns like chest discomfort due to restricted circulation. By reducing vascular tension, it eases the heart’s workload and enhances oxygen supply to tissues, making it a helpful choice for maintaining cardiovascular health under medical supervision.
Nicardia Retard 10mg is generally suitable for adults who require assistance in managing blood pressure or vascular stress. It may be considered for patients who experience frequent fluctuations in blood pressure or need short-term control to complement their long-term therapy. The tablet is typically taken after meals, swallowed whole with water, and at regular intervals as prescribed by the doctor to maintain consistent blood levels.
While using Nicardia Retard 10mg, it is important to follow all safety precautions. Avoid grapefruit juice, excessive alcohol, or high-sodium meals, as these can interfere with the medicine’s effectiveness. Regular monitoring of blood pressure and heart rate is recommended. Pregnant or breastfeeding women should use this medicine only under strict medical advice, as the doctor will weigh potential benefits against possible risks.
Common side effects may include headache, dizziness, facial flushing, mild nausea, or ankle swelling. These effects are often temporary, but if severe symptoms like sudden chest pain, rapid heartbeat, fainting, or breathing difficulty occur, immediate medical attention is necessary. Following a heart-healthy lifestyle, taking the medication as directed, and attending routine follow-ups can help maximize the benefits of Nicardia Retard 10mg.
Uses Of NICARDIA RETARD 10MG TABLET
- Manages high blood pressure (hypertension)
- Prevents chest pain (angina) related to heart disease
- Helps reduce the risk of heart attack and stroke
Benefits of NICARDIA RETARD 10MG TABLET
Nicardia Retard 10mg for Blood Pressure
Nicardia Retard 10mg helps in supporting smoother blood circulation by relaxing the blood vessels. This action allows blood to flow more easily, which assists in maintaining healthy blood pressure levels. It is often prescribed for individuals with consistently high blood pressure, helping reduce the strain on the heart and blood vessels. Regular monitoring and adherence to your doctor’s advice ensure effective results.
Nicardia Retard 10mg for Heart Health
By improving blood flow and reducing the pressure on arteries, Nicardia Retard 10mg contributes to better heart function. It aids in reducing the workload on the heart and supports the supply of oxygen-rich blood to the cardiac muscles. This makes it beneficial for people experiencing certain heart-related conditions under medical supervision. A healthy lifestyle alongside medication can further enhance heart health.
Nicardia Retard 10mg for Vascular Tension and Circulation
Nicardia Retard 10mg works by relaxing the smooth muscles in the blood vessel walls, which eases vascular tension. This relaxation promotes better blood circulation throughout the body and ensures that organs receive an adequate oxygen supply. Improved vascular flow can also help minimize symptoms related to restricted blood movement, like occasional discomfort or heaviness in the limbs.
How NICARDIA RETARD 10MG TABLET Works
Nicardia Retard 10mg Mechanism of Action
Nicardia Retard 10mg contains Nifedipine, a calcium channel blocker. It works by blocking the entry of calcium ions into the smooth muscles of blood vessel walls. This relaxation of blood vessels allows blood to flow more freely, reducing the strain on the heart. By lowering the resistance in the arteries, it supports smooth circulation and helps in maintaining healthier blood pressure levels.
Nicardia Retard 10mg Action in Blood Vessels
Nicardia Retard 10mg primarily acts on arterial blood vessels. By relaxing these vessels, it reduces vascular tension and increases the diameter of the arteries. This action improves blood flow, eases the heart’s pumping effort, and enhances oxygen delivery to body tissues. The effect on blood vessels also helps in reducing episodes of pressure-related discomfort and promotes overall circulatory health.
How to use NICARDIA RETARD 10MG TABLET
Take as prescribed by your doctor – Follow the exact dose and timing recommended.
Swallow the tablet whole with water – Do not crush, chew, or break it, as this may affect the slow-release action.
Preferably take after meals – This helps reduce the risk of stomach discomfort or sudden dizziness.
Take at the same time every day – Maintaining a routine ensures a steady effect in the body.
What if I forgot to take NICARDIA RETARD 10MG TABLET
If you forget to take Nicardia Retard 10mg Tablet, take the missed dose as soon as you remember it. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time or double the dose to make up for the missed one, as this may cause your blood pressure to drop too low. If you frequently forget doses, consider setting an alarm or asking your pharmacist for advice on how to remember your medication. Always follow your doctor’s instructions regarding the use of this medication.
Overdose
If an accidental overdose of Nicardia Retard 10mg Tablet occurs, seek immediate medical attention or visit the nearest hospital without delay. Signs of an overdose may include a significant drop in blood pressure, unusually fast or slow heartbeat, rise in blood sugar levels, increased blood acidity, fluid accumulation in the lungs, reduced oxygen levels in the blood, and altered consciousness that may progress to unconsciousness.
Side Effects Of NICARDIA RETARD 10MG TABLET
Common side effects of Nicardia retard 10mg:
- headache
- flushing or warmth in face
- general feeling of being unwell
- constipation
- dizziness
- Swelling of ankles or feet (edema)
When to Seek Medical Attention?
Stop taking NICARDIA RETARD 10MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- generalised allergic reaction including very rarely life-threatening shock (Ex. difficulty in breathing, drop of blood pressure, fast pulse, swelling including airway
- other allergic reactions like swelling of the skin (sometimes severe which includes swelling of the larynx)
- fast heartbeat (tachycardia)
- shortness of breath or difficulty breathing
- mild to moderate allergic reactions
- itching, rash or hives
How To Manage Side Effects
Constipation
Increase Fiber Intake
- Eat fibre-rich foods like whole grains, oats, beans, lentils, and fresh fruits such as papaya, apples, and pears.
- Include vegetables like spinach, carrots, and broccoli in your meals.
Stay Hydrated
- Drink 8–10 glasses of water daily to soften stools.
- Warm water in the morning can help stimulate bowel movements.
Natural Remedies
- Warm milk with 1 tsp ghee before bedtime may help in mild constipation.
- Soaked raisins, figs, or prunes in the morning act as natural laxatives.
- A spoon of isabgol (psyllium husk) mixed with water or warm milk can help soften stools.
Dizziness Or Drowsiness
- Rise slowly from sitting or lying down to avoid sudden drops in blood pressure that cause dizziness.
- Avoid activities requiring alertness, such as driving or operating machinery, until you know how the medicine affects you.
- Ensure adequate hydration to maintain stable blood pressure.
- Rest when feeling dizzy and avoid sudden head movements.
Headache
- Rest in a quiet, dark room to help alleviate headache symptoms.
- Apply a cool or cold compress to your forehead or temples for relief.
- Stay well-hydrated by drinking plenty of water to reduce headache intensity.
- Avoid caffeine and alcohol which can worsen headaches.
- If headache persists beyond a few days or is severe, consult your doctor.
Warning & Precautions
Pregnancy
Use with CautionNicardia Retard 10mg Tablet should be used with caution during pregnancy only if your doctor considers it necessary after carefully evaluating the potential benefits and risks. Always consult your doctor before taking this medicine if you are pregnant.
Breastfeeding
Use with CautionIf you are breastfeeding, Nicardia Retard 10mg Tablet should be used with caution and only under medical advice. Discuss with your doctor before starting the medicine.
Driving and Using Machines
Use with CautionAvoid driving or operating heavy machinery if you experience dizziness, sleepiness, extreme tiredness, fainting, or blurred vision after taking Nicardia Retard 10mg Tablet. Consult your doctor if these symptoms persist.
Alcohol
ContraindicatedIt is advisable to avoid alcohol while taking this medicine, as it can increase the risk of dizziness, fainting, fatigue, or visual disturbances.
Kidney
Use with CautionPatients undergoing kidney dialysis should take Nicardia Retard 10mg Tablet with caution. Use only under medical supervision.
Liver
Consult your doctorThis medicine is not recommended in severe liver disease and should be used cautiously if liver function is impaired. Always consult your doctor before use.
Allergy
ContraindicatedDo not take Nicardia Retard 10mg Tablet if you are allergic to nifedipine or any of its components.
Heart Disease
Use with CautionNicardia Retard 10mg Tablet medicine is not advised in individuals with a recent heart attack, unstable angina, sudden angina attacks, aortic valve narrowing (aortic stenosis), or cardiogenic shock (severe heart weakness). Patients with reduced heart function should use it cautiously and only under medical supervision.
Use In Pediatrics
ContraindicatedNicardia Retard 10mg Tablet is not advised for children or adolescents under 18 years of age. Always seek medical guidance from child’s doctor before using this medicine in younger individuals.
Other Warnings for NICARDIA RETARD 10MG TABLET
Before taking NICARDIA RETARD 10MG TABLET, inform your doctor if you have:
- low blood pressure
- diabetes
Who should not take [GBNKEYWORD
NICARDIA RETARD 10MG TABLET is not recommended for use if you have:
- Inflammatory bowel conditions like Crohn’s disease
- Blockage or narrowing of the intestines
- Obstruction in the oesophagus (the food pipe connecting throat and stomach)
- Presence of a Kock pouch, a surgically created intestinal reservoir with an abdominal opening
- Malignant hypertension, where blood pressure remains persistently high despite management
Safety Advice
- Take after meals if possible – Helps reduce the chance of stomach discomfort or dizziness.
- Avoid high-fat or very heavy meals – They can delay the absorption of the medicine.
- Avoid sudden position changes – Get up slowly from sitting or lying to prevent lightheadedness due to low blood pressure.
- Limit excessive caffeine – Too much coffee or energy drinks may reduce the relaxing effect on blood vessels.
- Inform your doctor before any surgery or dental procedure – Blood pressure medicines may interact with anaesthesia.
- Do not combine with over-the-counter decongestants – Some cold or flu medicines can raise blood pressure.
- Attend regular follow-ups – Allows your doctor to adjust dosage and monitor heart and kidney function.
Diet and Lifestyle Advice
- Follow a heart-healthy diet – Include fresh fruits, vegetables, whole grains, and lean proteins to support healthy blood pressure.
- Reduce salt intake – Limit processed, packaged, and salty foods to help manage fluid retention and ankle swelling.
- Limit caffeine – Excess caffeine may reduce the medicine’s effect.
- Maintain a healthy weight – Weight management reduces strain on the heart and improves blood pressure control.
- Exercise regularly – Gentle activities like walking, yoga, or swimming can support better heart health and blood flow.
- Avoid long periods of sitting or standing – Move around often to prevent swelling in the ankles and feet.
- Practice stress management – Deep breathing, meditation, or light stretching can help maintain stable blood pressure.
1. Comparison between Nicardia Retard 10mg and Amlodipine 5mg for managing blood pressure
|
Feature |
Nicardia Retard 10mg |
Amlodipine 5mg |
|
Active Ingredient |
Nifedipine 10mg |
Amlodipine 5mg |
|
Drug Class |
Calcium Channel Blocker (Dihydropyridine type) |
Calcium Channel Blocker (Dihydropyridine type) |
|
Release Type |
Retard (slow-release, shorter duration) |
Standard (long-acting) |
|
Dosing Frequency |
Usually 2–3 times a day |
Usually once daily |
|
Onset of Action |
Faster onset; works quickly to lower BP |
Slower onset, but maintains steady BP |
|
Duration of Effect |
Shorter; may need multiple doses |
Longer, provides 24-hour control |
|
Common Use |
Sudden or flexible BP control; sometimes for angina |
Long-term management of hypertension |
|
Side Effect Pattern |
Flushing, headache, ankle swelling (more frequent) |
Swelling, dizziness (less frequent) |
|
Doctor’s Preference |
For quick response or short-term therapy |
For stable, long-term blood pressure control |
2. Nicardia Retard 10mg vs Nicardia XL 30mg:
|
Feature |
Nicardia Retard 10mg |
Nicardia XL 30mg |
|
Active Ingredient |
Nifedipine 10mg |
Nifedipine 30mg |
|
Release Type |
Retard (slow release, but shorter duration) |
XL (extended release for longer duration) |
|
Dosing Frequency |
Usually 2–3 times a day (as prescribed) |
Usually once daily (as prescribed) |
|
Onset of Action |
Works faster but effect lasts for a shorter time |
Slower onset, but maintains steady effect |
|
Use Case |
Preferred for short-term or flexible dosing |
Preferred for long-term blood pressure control |
|
Convenience |
Less convenient due to multiple doses |
More convenient with single daily dose |
|
Doctor’s Advice |
Dose adjusted based on response and tolerance |
Often used for stable, consistent therapy |
Drug - Drug interaction
1. Beta-Blockers (e.g., Atenolol, Metoprolol)
- Interaction: May cause excessive lowering of blood pressure or slow heart rate when combined.
- Management: Blood pressure and heart rate should be monitored closely; dose adjustments may be required under medical supervision.
2. Other Blood Pressure Medicines (ACE inhibitors, ARBs, Diuretics)
- Interaction: Can enhance blood pressure-lowering effect, which may lead to dizziness or fainting.
- Management: Start with lower doses, monitor blood pressure regularly, and adjust medication as advised by your doctor.
3. CYP3A4 Inhibitors (e.g., Erythromycin, Clarithromycin, Ketoconazole, Ritonavir)
- Interaction: These drugs increase Nifedipine levels, raising the risk of headache, swelling, and low blood pressure.
- Management: Avoid combination if possible; if needed, careful dose monitoring and medical supervision are essential.
4. CYP3A4 Inducers (e.g., Rifampicin, Phenytoin, Carbamazepine)
- Interaction: These can reduce the effectiveness of Nicardia Retard 10mg.
- Management: Your doctor may adjust the dose or recommend an alternative medicine for better blood pressure control.
5. Anti-HIV Medicines (e.g., Protease Inhibitors like Ritonavir)
- Interaction: Can raise Nifedipine blood levels, increasing the chance of adverse effects.
- Management: Dose adjustments and close monitoring are recommended; discuss all HIV medications with your doctor.
6. Digoxin
- Interaction: Nicardia may increase digoxin levels, raising the risk of nausea, irregular heartbeat, or vision changes.
- Management: Regular monitoring of digoxin levels and heart function is advised.
7. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs like Ibuprofen)
- Interaction: May reduce the blood pressure-lowering effect of Nicardia Retard.
- Management: Use NSAIDs only when necessary and monitor blood pressure closely.
Drug - Food interaction
1. Grapefruit and Grapefruit Juice
- Interaction: Grapefruit can increase Nifedipine absorption in the blood, leading to stronger effects like headache, flushing, and low blood pressure.
- Management: Avoid grapefruit or its juice during therapy with Nicardia Retard.
2. High-Fat Meals
- Interaction: Heavy or high-fat meals may delay the absorption of the medicine, causing fluctuations in its effect.
- Management: Take Nicardia Retard after a light to moderate meal, as advised by your doctor.
3. Caffeine (Coffee, Tea, Energy Drinks)
- Interaction: Excess caffeine may counteract the relaxing effect on blood vessels and increase heart rate.
- Management: Consume caffeine in moderation and observe how your body responds while on the medicine.
4. High-Sodium Processed Foods
- Interaction: Salty and processed foods can worsen fluid retention and ankle swelling, reducing the effectiveness of blood pressure control.
- Management: Opt for a low-sodium diet with fresh fruits, vegetables, and whole grains.
5. Potassium-Rich Foods (in Large Quantities)
- Interaction: Though rare, excessive potassium (bananas, oranges, coconut water) combined with certain blood pressure medicines can affect heart rhythm.
- Management: Consume potassium-rich foods in moderate amounts, unless otherwise guided by your doctor.
Synopsis
|
Drug |
Nifedipine |
|
Pharmacological Category |
Calcium Channel Blockers |
|
Therapeutic Indication |
High Blood Pressure, Angina |
|
Dosage Forms |
Tablet, Capsule |
More Information
Storage
- Keep NICARDIA RETARD 10MG TABLET out of reach from children
- Store at room temperature
FAQs About NICARDIA RETARD 10MG TABLET
Q: What is Nicardia Retard 10 mg Tablet used for?
A: Nicardia Retard 10 mg Tablet is primarily prescribed to manage high blood pressure (hypertension) and prevent certain types of chest pain (angina). By relaxing and widening blood vessels, it improves blood flow, reduces the heart's workload and lowers the risk of heart attacks and strokes.
Q: Is Nicardia Retard 10 mg safe for liver problems?
A: Use Nicardia Retard cautiously if you have liver problems, as impaired liver function may affect how the drug is processed. Close medical supervision and possible dose adjustments are necessary to ensure safety in such cases.
Q: Can I take Nicardia Retard 10 mg with other heart medicines?
A: Combining Nicardia Retard with other heart medications should be done only under medical supervision. Some drug interactions can increase side effects or alter blood pressure control, so your doctor needs to monitor these combinations carefully.
Q: Is it normal to see the capsule shell in stool?
A: Yes, with sustained-release formulations like Nicardia Retard, the outer capsule shell or tablet remnants may pass in your stool because the medicine is released and absorbed earlier in the digestive tract. This is normal and not a cause for concern
Q: Does Nicardia Retard 10 mg affect my heart rate?
A: Nicardia Retard can sometimes cause your heart rate to become faster or slower due to its effects on blood vessels and reflex heart responses. If you notice significant or unusual changes in heartbeat, consult your doctor promptly.
Q: Why does this medicine sometimes cause swollen ankles?
A: Swelling of ankles or feet (peripheral edema) may occur as the blood vessels relax and fluid leaks into surrounding tissues. Elevating your legs and following your doctor's advice can help manage this common side effect.
Q: How does Nicardia Retard 10 mg Tablet work?
A: It works as a calcium channel blocker by preventing calcium ions from entering muscle cells in blood vessels and the heart. This causes relaxation and dilation of blood vessels, lowering blood pressure and decreasing the heart's workload, while improving oxygen supply to the heart.
Q: How long does Nicardia Retard 10 mg take to show effect?
A: The medicine starts lowering blood pressure within a few hours of taking it, but it requires regular use as prescribed to achieve full therapeutic benefits like sustained blood pressure control and reduction in angina episodes.
Q: Can this medicine cause headache or flushing?
A: Yes, headaches and facial flushing are common side effects when blood vessels dilate as the drug takes effect. These symptoms are typically mild and often improve with continued use.
Q: Can I stop taking Nicardia Retard 10 mg suddenly?
A: No, do not stop taking Nicardia Retard abruptly without your doctor's advice. Sudden discontinuation may cause rebound high blood pressure or worsen your symptoms. Always consult your healthcare provider before changing your dose or stopping this medication.
References
1. KD Tripathi. Antianginal and other anti-ischaemic drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page –592-597.
2. Morgan E Snider, Donald S Nuzum, and Angie Veverka . Long acting nifedipine in the management of the hypertensive patient. National Library of Medicine, National centre for biotechnology information. PubMed Central. [Revised in 2008]. [Accessed on 31st July 2025] 
3. M Witkowska, W Tracz, G Kubler, M Negrusz-Kawecka, M Hlawaty, M Olszowska, P Salamon. [Comparative study to assess the efficacy and adverse effects of amlodipine and nifedipine retard in patients with stable exertional angina and hypertension]. National Library of Medicine, National center for biotechnology information. PubMed Central. [Revised in1997]. [Accessed on 31st July 2025] 
4.Bayer Schering Pharma AG. Health product regulatory authority (HPRA). [Revised in 5th November 2014]. [Accessed on 31st July 2025].
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