NEZAFLO D 70md Nasal Spray 7g

Introduction About NEZAFLO D 70MD NASAL SPRAY

NEZAFLO D Nasal Spray is a corticosteroid and decongestant combination used for relief from allergic rhinitis symptoms including nasal congestion, sneezing, runny nose, and watery eyes.

This nasal spray Should be administered by the intranasal route only. Consult your doctor if you are pregnant or breastfeeding.

Patients are advised to consult their doctor before taking this medicine if they have high blood pressure, heart disease including angina, diabetes, thyroid disease, hepatic or renal disorders, narrow angle glaucoma or a male patient with difficulty urinating due to enlarged prostate gland.

It is not recommended for children below 4 years of age. The most commonly reported adverse reactions include sore throat, headache and dry nose. Consult your doctor in case of it persists.

Key Composition

• Fluticasone Propionate (a corticosteroid)
• Oxymetazoline hydrochloride (a nasal decongestant).

Uses Of NEZAFLO D 70MD NASAL SPRAY

• Manages Allergic rhinitis with nasal congestion

Benefits of NEZAFLO D 70MD NASAL SPRAY

• Provides quick and sustained relief from nasal congestion and allergy symptoms
• Reduces nasal swelling and irritation through corticosteroid action
• Improves breathing comfort by opening nasal passages with decongestant effect
• Supports improved quality of life during allergy seasons or perennial symptoms.

How NEZAFLO D 70MD NASAL SPRAY Works

• Fluticasone Propionate in NEZAFLO D works by binding to glucocorticoid receptors in nasal tissues, inhibiting the release of inflammatory mediators such as prostaglandins and leukotrienes that cause swelling, redness, and irritation in allergic rhinitis.
• Oxymetazoline is an alpha-adrenergic receptor agonist that causes vasoconstriction (shrinks blood vessels) in the nasal mucosa, reducing blood flow and swelling to relieve nasal congestion quickly.
• Together, these offer a combination of long-term anti-inflammatory benefits with fast-acting relief of blocked nasal passages, improving breathing and decreasing allergy symptoms.

How to use NEZAFLO D 70MD NASAL SPRAY

Directions for Use: NEZAFLO D Nasal Spray

• Use the nasal spray exactly as prescribed by your healthcare provider.
• Gently blow your nose before use to clear nasal passages.
• Shake the bottle gently before each use.

Recommended Dosage Schedule

• Insert the tip of the spray bottle into one nostril, closing the other nostril gently with a finger.
• While inhaling gently through the nostril, press the pump to release the spray.
• Repeat the process for the other nostril.
• Typically used once or twice daily as directed by your doctor, do not exceed prescribed dosage.

How to Use NEZAFLO D Nasal Spray Correctly

• Keep your head upright and avoid spraying directly onto the nasal septum (center cartilage).
• Breathe in gently during spray application to ensure the medicine reaches deep inside the nasal passages.
• Replace the cap tightly after use to maintain hygiene and medicine integrity.

Step-by-Step Administration Instructions

1. Prepare the spray by shaking gently.
2. Blow your nose gently to clear nostrils.
3. Tilt your head slightly forward and insert nozzle into one nostril.
4. Close the other nostril with a finger.
5. Spray once while gently inhaling through the nostril.
6. Repeat in the other nostril if instructed.
7. Wipe the nozzle clean and recap securely.

Important Precautions for Safe Use

• Do not exceed the recommended treatment duration to avoid rebound congestion or irritation.
• Avoid sharing the spray to prevent infections.
• Inform your doctor if you have recent nasal surgery, injury, or infections.
• Use caution in children, pregnant or breastfeeding women – consult your healthcare professional.
• Watch for side effects like nasal irritation, nosebleeds, or headaches and report persistent symptoms to your doctor.

What if I forgot to take NEZAFLO D 70MD NASAL SPRAY

• If you miss a dose, use it as soon as you remember.
• If it is close to the next dose, skip the missed dose.
• Do not double the dose to catch up.

Overdose

Overdosing is unlikely harmful, although it is best not to exceed the prescribed amount. Seek emergency medical attention or call your doctor if you notice any unusual symptoms, or anyone has accidentally swallowed the medication or if you suspect that you may have overdosed of Nezaflo-D Nasal Spray. Overuse or prolonged use beyond prescribed periods may cause rebound nasal congestion and other side effects.

Side Effects Of NEZAFLO D 70MD NASAL SPRAY

Common side effects

• Nasal irritation
• Dryness
• Nosebleeds
• Headache
• Sore throat
• Dizziness

When to consult a doctor?

• difficulty breathing, severe nosebleeds
• vision changes, or allergic reactions
• complications like nasal septum damage or infections.

Warning & Precautions

Pregnancy

Consult your doctor

There are no adequate data from the use of fluticasone furoate in pregnant women. If you are pregnant or planning pregnancy, inform your doctor before using Nezaflo-D Nasal Spray. Your doctor may prescribe this medicine if the benefits outweigh the risks.

Breastfeeding

Consult your doctor

Consult your healthcare provider before use if you are breastfeeding.

Driving and Using Machines

Use with Caution

Use caution when driving or operating machinery,  dizziness or blurred vision may occur rarely.

Alcohol

Consult your doctor

Avoid alcohol consumption as it may increase adverse effects

Kidney

Consult your doctor

It is advised to consult the doctor before taking Nezaflo-D Nasal Spray if you have kidney disorders.

Liver

Consult your doctor

It is advised to consult the doctor before taking Nezaflo-D Nasal Spray if you have liver disorders.

Allergy

Contraindicated

Avoid using NEZAFLO D if allergic to its ingredients or similar nasal sprays.

Lungs

Consult your doctor

Consult your healthcare provider before use of Nezaflo-D Nasal Spray if you have respiratory infections.

Heart Disease

Consult your doctor

Consult your doctor if you have high blood pressure or heart disease before using NEZAFLO D

Use In Pediatrics

Contraindicated

Children under 4 years should not use this nasal spray. Growth should be monitored in children with prolonged use.

Other Warnings for NEZAFLO D 70MD NASAL SPRAY

Before using Nezaflo-D Nasal Spray consult your doctor if you:

• have diabetes
• have thyroid disorders,
• have narrow-angle glaucoma
• have undergone recent trans-nasal surgery.
• Are male with enlarged prostate gland

Safety Advice

• You are recommended to remove nasal fluids before applying this spray, by blowing the nose.
• Avoid sharing this medicine with other people to prevent the spread of infection.
• It is recommended to avoid smoking and alcohol consumption as it may increase adverse effects

Drug - Drug interaction

• CYP3A4 inhibitors such as ritonavir, ketoconazole, itraconazole, and cobicistat-containing medicines. These drugs can increase fluticasone levels, potentially enhancing corticosteroid-related side effects.
• Simultaneous use with other corticosteroids may increase systemic corticosteroid effects.
• Oxymetazoline, as a nasal decongestant, should not be combined with other sympathomimetic agents to avoid excessive vasoconstriction.
• Inform your doctor about all medications, supplements, or herbal products you use to avoid harmful interactions.

Synopsis

More Information

Comparison with similar sprays

FAQs About NEZAFLO D 70MD NASAL SPRAY

Q: What is NEZAFLO D Nasal Spray used for?

A: It is used to relieve symptoms associated with allergic rhinitis such as sneezing, runny or blocked nose, nasal congestion, and itchy or watery eyes.

Q: How long does it take for NEZAFLO D Nasal Spray to work?

A: Symptom relief varies; some experience improvement within a few days, while full benefits may take up to two weeks of regular use.

Q: How should I use NEZAFLO D Nasal Spray?

A: Blow your nose gently, insert the spray tip into a nostril, close the other nostril, and spray while gently inhaling. Repeat for the other nostril as directed by your doctor.

Q: What should I do if I miss a dose?

A: Use the missed dose as soon as you remember unless it is close to the next dose. Do not double doses.

Q: Are there any side effects?

A: Common side effects include nasal irritation, nosebleeds, headache, and dryness. If side effects persist or worsen, consult your doctor.

Q: Can I use NEZAFLO D Nasal Spray during pregnancy or breastfeeding?

A: Consult your healthcare provider before use to assess potential risks and benefits.

Q: Can I share NEZAFLO D Nasal Spray with others?

A: No, to prevent the spread of infections, the spray should not be shared.

Q: What precautions should I keep in mind?

A: Avoid overuse to prevent rebound congestion, and inform your doctor about any nasal injuries, infections, or surgeries.

References

1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page 228.
2. R S Kumar, Manish Kumar Jain, Jitendra Singh Kushwaha. Efficacy and Safety of Fluticasone Furoate and Oxymetazoline Nasal Spray: A Novel First Fixed Dose Combination for the Management of Allergic Rhinitis with Nasal Congestion. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed. June 2022. [Accessed on 1st Novemebr 2025] 
3. Luckyspharma. FURATE – OX Nasal Spray [Accessed on 1st November 2025] 
4. Cafoli. Flutialfa O Nasal Spray. [Accessed on 1st November 2025] 

    

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 04 Nov 2025 | 12:07 PM(IST)