Macleods Pharmaceuticals Pvt Ltd

NEXOVAS T Tablet 10's

Hypertension
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    Introduction About NEXOVAS T TABLET

    NEXOVAS T Tablet combines Cilnidipine (10 mg) and Telmisartan (40 mg) support healthy blood pressure levels by relaxing and widening blood vessels. This dual-action approach helps improve circulation and reduce strain on the heart.

    Cilnidipine blocks calcium entry into blood vessel muscles, promoting vessel widening and reducing tension. Telmisartan blocks the effects of a hormone that narrows blood vessels, leading to improved blood flow and reduced cardiac workload.

    Take the tablet whole with water, preferably at the same time each day for consistent effects. Do not crush or chew the tablet to ensure proper release of active ingredients. Regular monitoring by your healthcare provider is important for optimal management. Complement medication with lifestyle habits such as a balanced diet low in salt and fat, regular physical activity, and avoiding smoking.

    Inform your healthcare provider of any existing kidney or liver issues before starting NEXOVAS T. Avoid alcohol consumption while taking this medication, as it may increase dizziness or low blood pressure. Inform the provider about all current medications to manage interactions. Pregnant or breastfeeding individuals should seek medical advice prior to use.

    The most common effects may include dizziness, headache, swelling in the feet or ankles, fatigue, and mild stomach discomfort. If side effects persist or cause concern, consult a healthcare provider promptly.

    Uses Of NEXOVAS T TABLET

    Benefits of NEXOVAS T TABLET

    • Contains a blend of Cilnidipine (a calcium channel blocker) and Telmisartan (an angiotensin receptor blocker)
    • Supports steady and balanced blood flow through vessel relaxation
    • Helps maintain normal blood pressure levels, contributing to overall cardiovascular health
    • Recommended to be taken once daily, with or without food, as advised by healthcare professionals

    How NEXOVAS T Tablet Supports Healthy Blood Pressure

    NEXOVAS T Tablet supports healthy blood pressure by combining the complementary actions of two ingredients:

    • Cilnidipine, a calcium channel blocker, and Telmisartan, an angiotensin II receptor blocker (ARB)
    • By enhancing blood vessel relaxation and reducing vascular constriction, NEXOVAS T Tablet improves blood flow and lowers the workload on the heart. It is especially beneficial for patients whose blood pressure is not adequately controlled by a single medication
    • For best results, patients are advised to take the medication at the same time each day, with or without food, and to maintain lifestyle modifications such as following a low-sodium diet, exercising regularly, and avoiding smoking and excessive alcohol

    How NEXOVAS T TABLET Works

    Cilnidipine blocks calcium entry into blood vessel muscles, promoting vessel widening and reducing tension. Telmisartan blocks the effects of a hormone that narrows blood vessels, leading to improved blood flow and reduced cardiac workload.

    Importance of Vasodilation in Blood Pressure Control

    • Vasodilation plays a crucial role in controlling blood pressure by relaxing and widening blood vessels, which helps reduce the resistance the heart faces when pumping blood
    • When blood vessels dilate, the diameter increases, allowing blood to flow more freely and lowering the overall pressure within the arterial system. This process significantly contributes to maintaining a healthy blood pressure range and reducing the workload on the heart
    • Vasodilation helps counteract this by relaxing the smooth muscle lining the vessel walls, improving circulation and oxygen delivery to tissues
    • Maintaining vasodilation not only helps control blood pressure but also protects vital organs such as the heart, brain, and kidneys from damage caused by high pressure. It contributes to overall cardiovascular health and reduces the risk of complications like stroke and heart attack

    How to use NEXOVAS T TABLET

    1. Usage Guidelines of Nexovas T Tablet

    • Take the tablet whole with water, preferably at the same time each day for consistent effects
    • Do not crush or chew the tablet to ensure proper release of active ingredients
    • Regular monitoring by your healthcare provider is important for optimal management
    • Complement medication with lifestyle habits such as a balanced diet low in salt and fat, regular physical activity, and avoiding smoking

    2. Recommended Dosage of NEXOVAS T Tablet

    • NEXOVAS T Tablet is usually prescribed to be taken once daily with the dosage and duration determined by your healthcare provider based on your blood pressure condition and response to the medication
    • It is important to adhere strictly to your doctor's prescription without altering the dose independently
    • The tablet should be swallowed whole with water and can be taken either on an empty stomach or with food according to personal tolerance or as advised

    3. Best Time to Take NEXOVAS T Tablet

    • It is recommended to take NEXOVAS T at the same time every day which helps maintain a steady level of the medication in your bloodstream and maximizes its benefit
    • You can choose a convenient time, such as morning or evening, but consistency in timing is key

    What if I forgot to take NEXOVAS T TABLET

    • If you miss a dose of NEXOVAS T Tablet, take it as soon as you remember
    • If it is almost time for your next scheduled dose, skip the missed one without doubling the dose to catch up

    Overdose

    If you or anyone else accidentally take too much of consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of NEXOVAS T TABLET are low blood pressure, fast or slow heart rate, dizziness, increase in serum creatinine, acute renal failure, excessive peripheral vasodilatation.

    Side Effects Of NEXOVAS T TABLET

    Potential Side Effects

    • dizziness
    • headache
    • swelling in the feet or ankles
    • fatigue
    • mild stomach discomfort

    Tips to Minimize Side Effects During Treatment

    1. Take Medication as Directed

    2. Maintain Proper Hydration

    3. Rise Slowly from Sitting or Lying Position

    4. Avoid Alcohol Consumption

    5. Monitor for Swelling and Manage Accordingly

    6. Limit Potassium-Rich Foods and Supplements

    7. Report Persistent or Serious Side Effects to your healthcare provider

    Warning & Precautions

    Pregnancy

    Consult your doctor

    Pregnant women should seek medical advice prior to use of Nexovas F Tablet.

    Breastfeeding

    Consult your doctor

    Breastfeeding women should seek medical advice prior to use of Nexovas F Tablet.

    Driving and Using Machines

    Use with Caution

    Do not drive or handle any machines if you experience dizziness after taking NEXOVAS T TABLET.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking NEXOVAS T TABLET as it may cause low blood pressure or dizziness.

    Kidney

    Use with Caution

    NEXOVAS T TABLET should be used with caution in patients with chronic renal insufficiency. It should be used with caution in patients with impaired kidney function, bilateral renal artery stenosis or stenosis of the artery to a single functioning kidney.

    Liver

    Consult your doctor

    NEXOVAS T TABLET is not recommended for use in patients with severe liver impairment, cholestasis, biliary obstructive disorders. It should be used with caution in patients with mild to moderate liver impairment and elevated liver enzymes.

    Allergy

    Contraindicated

    Do not take NEXOVAS T TABLET if you are allergic to Telmisartan, Cilnidipine or any other ingredients of this medicine.

    Heart Disease

    Consult your doctor

    NEXOVAS T TABLET is not recommended for use in patients with advanced aortic stenosis. It should be used with caution in patients with aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy, angina, ischaemic cardiopathy or ischaemic cardiovascular disease and congestive heart failure.

    Use In Pediatrics

    Contraindicated

    NEXOVAS T TABLET is not recommended for use in children and adolescents (aged below 18 years).

    Use In Geriatrics

    Use with Caution

    NEXOVAS T TABLET should be used with caution in elderly patients (aged 65 years and above).

    Other Warnings for NEXOVAS T TABLET

    Before taking NEXOVAS T TABLET, inform your doctor if you:

    • have Volume and/or sodium depletion by diuretic therapy, dietary salt restriction, diarrhoea or vomiting
    • have Diabetes
    • have Peripheral edema
    • have Metabolic acidosis, cellular lysis

    Who should not take NEXOVAS T TABLET

    NEXOVAS T TABLET is not recommended for use if you:

    • have primary aldosteronism

    Safety Advice

    Important Precautions

    • Inform your healthcare provider of any existing kidney or liver issues before starting NEXOVAS T TABLET
    • Avoid alcohol consumption while taking this medication, as it may increase dizziness or low blood pressure
    • Inform the provider about all current medications to manage interactions
    • Pregnant or breastfeeding individuals should seek medical advice prior to use

    Diet and Lifestyle Advice

    • Diet and lifestyle modifications are essential complements to NEXOVAS T Tablet’s role in supporting healthy blood pressure levels and cardiovascular well-being. Patients are advised to follow a heart-healthy diet that includes plenty of fresh fruits, vegetables, whole grains, and lean proteins while limiting salt (sodium), saturated fats, and processed foods. Reducing sodium intake helps manage fluid retention and blood vessel constriction, enhancing the medication’s effectiveness.
    • Regular physical activity, such as walking, swimming, or cycling for at least 30 minutes most days of the week, supports cardiovascular fitness and promotes blood circulation. Avoiding tobacco products and limiting alcohol consumption is critical, as smoking and excessive alcohol intake can interfere with blood pressure control and lead to increased cardiovascular risks
    • Stress management techniques like mindfulness meditation, yoga, or deep breathing exercises may help lower blood pressure by reducing stress-induced vascular constriction. Maintaining a healthy weight and staying well-hydrated further support vascular health and heart function, contributing to better overall outcomes with NEXOVAS T Tablet therapy.

    Drug - Drug interaction

    Interacting Drug

    Interaction Effect

    Precautions/Recommendations

    Diuretics (e.g., hydrochlorothiazide)

    Increased blood pressure lowering effect; risk of low blood pressure or electrolyte imbalance

    Monitor blood pressure and electrolyte levels; adjust dosage if necessary

    Lithium

    Increased lithium levels leading to toxicity

    Avoid combination or closely monitor lithium levels

    NSAIDs (e.g., ibuprofen)

    Reduced antihypertensive effect; increased risk of kidney damage

    Use cautiously, especially in patients with kidney issues; monitor renal function

    Potassium supplements or potassium-sparing diuretics

    Increased risk of hyperkalemia (high potassium levels)

    Avoid concurrent use or monitor potassium levels regularly

    Other Antihypertensives

    Additive blood pressure lowering effects

    Monitor blood pressure to avoid hypotension

    CYP3A4 Inhibitors (e.g., ketoconazole)

    May increase Cilnidipine levels leading to enhanced effects or side effects

    Use with caution; monitor for side effects

    Synopsis

    Drug :   Cilnidipine, Telmisartan
    Pharmacological Category :   Calcium channel blockers, Angiotensin II receptor antagonists
    Therapeutic Indication :   Hypertension
    Dosage Forms :   Tablet

    More Information

    Explain why these habits matter in conjunction with the tablet for holistic wellness

    • Enhance Medication Effectiveness: Healthy habits such as a balanced diet and regular exercise complement NEXOVAS T Tablet by helping to naturally regulate blood pressure and reduce cardiovascular strain
    • Reduce Side Effects: Avoiding alcohol and smoking minimizes additional vascular stress and potential interaction risks, improving medication tolerance and decreasing side effect incidence
    • Support Cardiovascular Health: Low-sodium diets and physical activity improve blood vessel elasticity and heart function, augmenting the tablet’s vasodilatory and antihypertensive effects
    • Promote Weight Management: Maintaining a healthy weight reduces the workload on the heart and blood vessels, enhancing overall blood pressure control alongside the medication
    • Improve Compliance and Outcomes: Lifestyle adjustments encourage patient engagement and adherence, leading to sustained blood pressure management and better long-term health outcomes.
    • Manages Comorbidities: Managing stress, diet, and activity lowers risks of diabetes and kidney issues, conditions that can complicate hypertension and affect treatment response

    How NEXOVAS T differs from single-component drugs or other combination therapies, emphasizing the dual mechanism benefits?

    • NEXOVAS T Tablet differs from single-component drugs and other combination therapies primarily due to its dual mechanism of action, combining Cilnidipine and Telmisartan. Cilnidipine, a unique dual L- and N-type calcium channel blocker, relaxes blood vessels by inhibiting calcium influx and also reduces sympathetic nerve activity, resulting in less peripheral edema compared to traditional L-type blockers like amlodipine. Telmisartan, an angiotensin II receptor blocker, complements this by managing hormone-mediated vessel constriction, leading to effective and sustained blood pressure reduction
    • This combination provides enhanced efficacy through synergistic effects on vascular relaxation and hormonal regulation, targeting multiple pathways involved in hypertension. Compared to single drugs, it offers superior blood pressure control, reduced side effects such as pedal edema, and added organ protection benefits, including renal and cardiovascular support.
    • NEXOVAS T demonstrates better tolerability, potentially improving patient adherence and outcomes in diverse populations, especially those with metabolic or renal concerns.
    • In summary, NEXOVAS T's dual-action approach targets both neural and hormonal contributors to hypertension, delivering comprehensive blood pressure management with an improved safety profile, distinguishing it from monotherapies and standard fixed-dose combinations

     

    FAQs About NEXOVAS T TABLET

    Q: What is NEXOVAS T TABLET used for?

    A: NEXOVAS T TABLET is a combination medicine used to manage high blood pressure (hypertension). It helps relax and widen blood vessels, making it easier for the heart to pump blood, thus reducing the risk of complications like heart attacks and strokes.

    Q: How should I take NEXOVAS T TABLET?

    A: Take NEXOVAS T TABLET exactly as prescribed by your doctor. Swallow the tablet whole with water, with or without food. It is best to take it at the same time each day for consistent blood pressure control. Do not stop taking it without consulting your doctor, even if you feel well.

    Q: What are the possible side effects of NEXOVAS T TABLET?

    A: The most Common side effects include swelling in the ankles or feet (edema), dizziness, headache, fatigue, nausea, sleepiness, taste changes, and an upset stomach. Most side effects are mild and resolve on their own, but consult your doctor if they persist or worsen.

    Q: Can NEXOVAS T TABLET cause dizziness?

    A: Yes, dizziness is a common side effect of NEXOVAS T TABLET , especially when starting the medication or increasing the dose. To reduce dizziness, avoid sudden movements and get up slowly from sitting or lying positions. Avoid driving, using machineries or performing activities that requires concentration. Talk to your doctor if dizziness worsens or troubles you.

    Q: Can I stop taking NEXOVAS T TABLET once my blood pressure is normal?

    A: No, do not stop taking this medication unless advised by your doctor. High blood pressure often has no symptoms, and discontinuing treatment may cause it to rise again, increasing the risk of heart problems.

    Q: Can I take NEXOVAS T TABLET with other medications?

    A: Inform your doctor about all other medications you are taking, including over-the-counter drugs and supplements. Telma LN 40mg may interact with certain drugs, such as diuretics, NSAIDs, or lithium, which can affect its efficacy or increase side effects.

    Q: What precautions should I take while using NEXOVAS T TABLET ?

    A: Avoid alcohol, as it may increase dizziness. Inform your doctor if you have kidney or liver problems, severe dehydration, or if you are taking other blood pressure medications. Regularly monitor your blood pressure and kidney function during treatment.

    Q: How long does it take for NEXOVAS T TABLET to show results?

    A: The medication may take a few weeks to show full effectiveness. However, you may notice improvements in your blood pressure readings sooner. Continue taking the medicine as prescribed, even if you don’t feel immediate effects.

    Q: What lifestyle changes can enhance the effectiveness of NEXOVAS T TABLET ?

    A: To complement the treatment, adopt a healthy lifestyle. Exercise regularly, follow a low-sodium and low-fat diet, maintain a healthy weight, quit smoking, and limit alcohol consumption. These measures can help improve blood pressure control and overall heart health.

    Q: What to do if I miss to take a dose of NEXOVAS T TABLET?

    A: You should take NEXOVAS T TABLET immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.

    Q: For how long should I take NEXOVAS T TABLET?

    A: You should continue taking NEXOVAS T TABLET unless your doctor tells you to stop the medicine. Blood pressure medicines will be usually taken for lifetime to manage complications due to high blood pressure. Your doctor may change management with other hypertensive drug, if you do not attain effective therapeutic outcome with NEXOVAS T TABLET.

    References

    1. KD. Tripathi. Antianginal and other Anti-ischaemic Drugs & Drugs Affecting Renin Angiotensin System. Eighth edition. June 2018. Page – 596 & 536.

    2. C Venkata S Ram, Baby Shalini Muppalla, Sarvepalli Vijaya Parthasaradhi, Gajjela Praveen Kumar, Saumitra Ray, Uday Jadhav, J P S Sawhney, Govindan Unni, Nagaraj Desai, Members of the TelCom Study Group. Achieving the Latest American Heart Association and American College of Cardiology Therapeutic Goals for Hypertension With Combination Therapy and Its Effects on Blood Pressure and Central Hemodynamic Parameters. NIH National Library of Medicine. National Centre for Biotechnology Information. Pubmed.gov. April 2022. [Accessed on 12th November 2025] 

    3. Pure & Cure Healthcare Pvt. Ltd. Cilacar T (Cilnidipine and Telmisartan Tablets). January 2020. [Accessed on 12th November 2025] 

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)
    Last updated on 28 Nov 2024 | 04:01 PM(IST)
    Lab updated