Nervz D Tablet 10'S

Introduction About NERVZ D TABLET

NERVZ D TABLET contains Alpha Lipoic Acid, Folic Acid, Methyl cobalamin, Pyridoxine, and Cholecalciferol (Vitamin D3), which belong to the group of medicines called Antioxidants and Vitamin supplements, respectively. It is used to manage diabetic neuropathy (diabetic nerve damage).

NERVZ D TABLET is also used for the management of alcoholic neuropathy (damage to the nerves due to excessive alcohol intake), diabetic retinopathy (diabetic eye disease), peripheral neuropathy (weakness, numbness, and pain usually in the hands and feet), degenerative diseases like Parkinson’s disease (a brain disorder that affects movement) and Alzheimer’s disease (a brain disorder that affects memory and thinking), chronic pain, and vitamin deficiency.

NERVZ D TABLET is not recommended for use if you have hypercalcaemia (increased levels of calcium levels in the blood), malabsorption syndrome (difficulty absorbing nutrients from the diet), or hypervitaminosis D (increased level of vitamin D in the body). Consult your doctor before taking it.

NERVZ D TABLET should be used with caution in patients suffering from kidney impairment, kidney stones, or heart problems. Consult your doctor before taking it.

NERVZ D TABLET should be used with caution by pregnant and breastfeeding women. Consult your doctor if you experience any side effects after taking this medicine.

Uses Of NERVZ D TABLET

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NERVZ D TABLET is used for the management of:

• Diabetic neuropathy
• Alcoholic neuropathy
• Diabetic retinopathy
• Peripheral neuropathy
• Parkinson’s disease
• Alzheimer’s disease
• Chronic pain
• Vitamin deficiency

How NERVZ D TABLET Works

NERVZ D TABLET helps to manage neuropathies and supports the health of the brain, where alpha-lipoic acid, an antioxidant, delays or reverses diabetic neuropathy. Folic acid is useful for enhancing nerve conduction velocity in diabetic neuropathy. Methylcobalamin works by producing a compound called myelin, which covers and protects nerve fibers and helps to rejuvenate the damaged nerves. Pyridoxine is an essential nutrient that is required for the metabolism of lipids, carbohydrates, and proteins. It is also needed for the synthesis of neurotransmitters (chemical messengers), and vitamin D increases the level of nerve growth factor (which helps in the development and survival of nerves) by stimulating its production and managing its depletion.

How to use NERVZ D TABLET

Take NERVZ D TABLET as advised by your physician. Swallow NERVZ D TABLET with a glass of water, and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Warning & Precautions

Pregnancy

Use with Caution

NERVZ D TABLET should be used with caution in pregnant women. Consult your doctor before taking NERVZ D TABLET.

Breastfeeding

Use with Caution

NERVZ D TABLET should be used with caution in breastfeeding women as it may pass through breast milk. Consult your doctor before taking NERVZ D TABLET.

Alcohol

Contraindicated

Do not consume alcohol while taking NERVZ D TABLET, as it impairs the absorption of Vitamin B12 from the stomach and intestine.

Kidney

Use with Caution

NERVZ D TABLET should be used with caution in patients suffering from kidney impairment and kidney stones. Consult your doctor before taking NERVZ D TABLET.

Allergy

Contraindicated

Do not take NERVZ D TABLET if you are allergic to alpha-lipoic acid, folic acid, methyl cobalamin, pyridoxine, cholecalciferol (Vitamin D3), or any other ingredients of this medicine.

Heart Disease

Use with Caution

NERVZ D TABLET should be used with caution in patients suffering from heart problems. Consult your doctor before taking NERVZ D TABLET.

Interactions

A. Drug-Drug interactions:

Before taking NERVZ D TABLET, inform your doctor if you are taking any of the following medicines:

• Isoniazid, amino-salicylic acid, rifampicin (medicines used to manage tuberculosis)
• Oral contraceptives (medicines used to manage pregnancy) (Ex. oestradiol valerate)
• Levodopa (a medicine used to manage Parkinson’s disease)
• Penicillamine, neomycin, chloramphenicol, and co-trimoxazole (medicines used to manage bacterial infections)
• Colchicine (used for the management of gout)
• Methotrexate (used to manage rheumatoid arthritis and cancer)
• Medicines used to manage peptic ulcers (Ex. cimetidine, omeprazole, and lansoprazole)
• Mercaptopurine (a medicine used for the management of leukemia)
• Altretamine (a medicine used to manage ovary cancer)
• Antiepileptics (medicines used to manage fits) (Ex. phenytoin, phenobarbital, primidone, carbamazepine)
• Sulfasalazine (a medicine used to manage ulcerative colitis and Crohn’s disease)
• Ketoconazole (a medicine used for the management of fungal infections)
• Mineral oil
• Corticosteroids (medicines used for the management of inflammatory conditions)
• Vitamin C supplements
• Potassium supplements
• Thiazide diuretics (used to manage high blood pressure and heart diseases) (Ex. chlorothiazide, hydrochlorothiazide)
• Calcium or phosphate supplements
• Paricalcitol (used to manage hypoparathyroidism)

Overdosage:

If you or anyone else accidentally uses too much of NERVZ D TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage include loss of appetite, weakness, weight loss, vague aches and stiffness, nausea and vomiting, constipation or diarrhea, polyuria (increased urination), nocturia (frequent urination at night), polydipsia (increased thirst), sweating, headache, somnolence, vertigo, mental retardation, anemia (decreased in red blood cell count) and mild acidosis, hypercalciuria (excess calcium in urine), reversible azotemia (elevation of metabolic products), high blood pressure, nephrocalcinosis (deposition of calcium in the kidneys), generalized vascular calcification (abnormal accumulation of calcium in blood) or irreversible kidney damage which may result in death.

Widespread accumulation of calcium in the heart, blood vessels, renal tubules, and lungs. Bone demineralization (osteoporosis) in adults occurs concomitantly. A decline in the average rate of linear growth and increased mineralization of bones in infants and children (dwarfism) may also occur.

Synopsis

More Information

FAQs About NERVZ D TABLET

Q: How often can I take NERVZ D TABLET?

A: Take NERVZ D TABLET as advised by your physician. Take one or two tablets, or as directed by your doctor. Swallow NERVZ D TABLET with a glass of water, and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Q: What are the side effects of taking NERVZ D TABLET?

A: NERVZ D TABLET is possibly safe for most adults. There is no disadvantage associated with this medicine if taken at the recommended dosage. However, some may experience side effects such as headaches, nausea, vomiting, and an upset stomach. Consult your doctor if any of the symptoms worsen.

Q: Is NERVZ D TABLET safe in pregnancy?

A: Yes. NERVZ D TABLET should be used with caution in pregnant women. Inform your doctor if you are pregnant or planning to be pregnant before taking this medicine.

Q: For what conditions is NERVZ D TABLET used?

A: NERVZ D TABLET is used to manage diabetic neuropathy. It is also used for the management of alcoholic neuropathy, diabetic retinopathy, peripheral neuropathy, degenerative diseases like Parkinson’s disease and Alzheimer’s disease, chronic pain, and vitamin deficiency. Consult your doctor before taking it.

Q: Who should not take NERVZ D TABLET?

A: NERVZ D TABLET is not recommended for use if you have hypercalcaemia (increased levels of calcium levels in the blood), malabsorption syndrome (difficulty absorbing nutrients from the diet), abnormal sensitivity to the toxic effects of vitamin D, or hypervitaminosis D (increased level of vitamin D in the body). Consult your doctor before taking it.

Q: How does NERVZ D TABLET work?

A: NERVZ D TABLET helps to manage neuropathies and supports the health of the brain, where alpha-lipoic acid, an antioxidant, delays or reverses diabetic neuropathy. Folic acid is useful for enhancing nerve conduction velocity in diabetic neuropathy. Methylcobalamin works by producing a compound called myelin, which covers and protects nerve fibers and helps to rejuvenate the damaged nerves. Pyridoxine is an essential nutrient that is required for the metabolism of lipids, carbohydrates, and proteins. It is also needed for the synthesis of neurotransmitters (chemical messengers), and vitamin D increases the level of nerve growth factor (which helps in the development and survival of nerves) by stimulating its production and managing its depletion.

Q: Can NERVZ D TABLET be used with children?

A: There is no information on the use of NERVZ D TABLET in children. Consult your doctor before taking it.

Q: What should I avoid while taking NERVZ D TABLET?

A: Do not consume alcohol while taking NERVZ D TABLET, as it impairs the absorption of Vitamin B12 from the stomach and intestine.

Q: What precautions must be taken while using NERVZ D TABLET?

A: Before taking NERVZ D TABLET, inform your doctor if you have kidney impairment and kidney stones, heart problems, folate deficiency, megaloblastic anemia (a type of red blood cell disorder), Leber’s disease (a hereditary eye disease), vitamin B12 deficiency, or folate-dependent cancers.

Q: Can I take other medicines along with NERVZ D TABLET?

A: Before taking NERVZ D TABLET, inform your doctor if you are taking prescription, non-prescription, or herbal medicines.

References

1. KD Tripathi. Drugs Affecting Blood and Blood Formation, Vitamins, Hormones, and Related Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 608, 915, 340.

2. Aylin Sari, Zeynep Akdogan Altun, Cigdem Arifoglu Karaman, Basak Bilir Kaya, and Bekir Durmus. Does vitamin D affect diabetic-neuropathic pain and balance. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central.  January 2020. [Accessed on 1st July 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970609/

3. Ming Zhang, Wenjuan Han, Sanjue Hu, and Hui Xu. Methylcobalamin: a potential vitamin of pain killer. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central.  December 2013. [Accessed on 1st July 2024]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888748/

4. Akums Drugs & Pharmaceuticals Ltd. (Alpha Lipoic Acid, Methyl Cobalamin, Folic Acid, Pyridoxine, and Cholecalciferol). [Revised in June 2018] [Accessed on 1st July 2024]. https://www.torrentian.com/pisheet/Upload/PI_Sheet/2663.pdf

5. GLIAREN-D Tablet (Alpha Lipoic Acid, Methyl Cobalamin, Folic Acid, Pyridoxine, and Cholecalciferol). La Renon Healthcare Private Limited. [Accessed on 1st July 2024] https://www.larenon.com/wp-content/uploads/2020/12/GLIAREN-D-_-LBL.pdf

6. Myovit-D3 (Alpha Lipoic Acid, Methyl Cobalamin, Folic Acid, Pyridoxine, Cholecalciferol). Solitaire Pharmacia Pvt. Ltd. [Accessed on 1st July 2024] www.solitairepharmacia.co.in/methylcobalamin-1500-mcg-alpha-lipoic-acid-100-mg-folic-acid-1-5-mg-pyridoxine-3-mg-vit-d3-1000-i-u--5666651.html

7. Meconic Plus Tablet (Alpha Lipoic Acid, Methyl Cobalamin, Folic Acid, Pyridoxine, Cholecalciferol). Bionics Remedies. [Accessed on 1st July 2024] http://www.bionicsremedies.com/HAEMETINIC-MULTIVITAMIN-MULTI%20MINERAL-ANTIOXIDANT-CALCIUM-NUTRITION-PRODUCTS.php#c72

8. Neuronis-D3 Tablet (Alpha Lipoic Acid, Methyl Cobalamin, Folic Acid, Pyridoxine, Cholecalciferol). Nutronis Lifesciences Pvt. Ltd. [Accessed on 1st July 2024] http://nutronis.com/Product_Details.aspx?Product_ID=9

9. GM Vital (Alpha Lipoic Acid, Methyl Cobalamin, Folic Acid, Pyridoxine, Cholecalciferol). Alaina Pharma. [Accessed on 1st July 2024] http://alainapharma.com/Methylcobalamin,%20Vitamin%20B1,%20Alphalipoic%20Acid,%20Folic%20Acid%20and%20Vitamin%20D3%20Tablet.html

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Phosphorus-Inorganic, Serum
• Calcium
• Vitamin B-12
• Vitamin B Complex Profile
• Vitamin Basic Package
• Vitamin D 1,25 Dihydroxy
• 25 Oh Vitamin D (Total) (D2+D3)

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed For Accuracy By Dr. Shruthi Raikar - BDS

Last updated on 02 Jul 2024 | 04:40 PM(IST)