Neosporin H Ear Drops 5ml

Introduction About NEOSPORIN H EAR DROPS

NEOSPORIN H EAR DROPS is a combination of Polymyxin B, Neomycin and Hydrocortisone which belongs to the group of medicines called Antibacterial and Anti-inflammatory. It is used for the management of otitis externa (infection of the external auditory canal). It is also used for the management of infections of mastoidectomy and fenestration cavities.

NEOSPORIN H EAR DROPS is not recommended for use in patients with perforation of the tympanic membrane, herpes simplex and herpes zoster infections, vaccinia or fungal infections. Contact your doctor before using NEOSPORIN H EAR DROPS should be used with caution in patients with allergic asthma or kidney disease.

NEOSPORIN H EAR DROPS is not recommended for use during pregnancy or breastfeeding. Contact your doctor before using NEOSPORIN H EAR DROPS is not recommended for neonates and infants younger than 2 years of age. NEOSPORIN H EAR DROPS should be used with caution in patients over the age of 65. If you experience any side effects, contact your doctor.

Uses Of NEOSPORIN H EAR DROPS

• Manage otitis externa (infection of the external auditory canal)
• Manage infections of mastoidectomy and fenestration cavities

How NEOSPORIN H EAR DROPS Works

NEOSPORIN H EAR DROPS helps to manage ear infections, whereas Polymyxin B is Antibacterial and works by damaging the cell membrane of bacteria (which is essential for survival) leading to death. Neomycin is an Aminoglycoside antibiotic that works by inhibiting protein synthesis causing cell death and Hydrocortisone is a steroid which blocks the production of certain chemical messengers called prostaglandins (which are responsible for pain, inflammation and allergy). Together manages ear infection effectively.

How to use NEOSPORIN H EAR DROPS

Clean and dry the ear with sterile cotton and instil NEOSPORIN H EAR DROPS into the affected ear as advised by your physician. Shake well before use. It is for external use only. Do not use it in the eyes.

Side Effects Of NEOSPORIN H EAR DROPS

Warning & Precautions

Pregnancy

NEOSPORIN H EAR DROPS is not recommended for use in pregnancy. Contact your doctor before using it.

Breastfeeding

NEOSPORIN H EAR DROPS is not recommended for use in breastfeeding women. Contact your doctor before using it.

Kidney

NEOSPORIN H EAR DROPS should be used with caution in patients with kidney disease. Contact your doctor before using it.

Allergy

Do not use NEOSPORIN H EAR DROPS if you are allergic to Polymyxin B, Neomycin, Hydrocortisone or antibiotics like framycetin, kanamycin, paromomycin, streptomycin, gentamicin or to other ingredients of this medicine.

Lungs

NEOSPORIN H EAR DROPS should be used with caution in patients with allergic asthma. Contact your doctor before using it.

Interactions

A. Drug-Drug interactions:

Before using NEOSPORIN H EAR DROPS, inform your doctor if you are using any of the following medicine:

• neuromuscular blocking agents Ex. succinylcholine (medicines used in anaesthesia)

Overdosage:

If you or anyone else accidentally take too much of NEOSPORIN H EAR DROPS, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep NEOSPORIN H EAR DROPS out of the sight and reach from children
• Store NEOSPORIN H EAR DROPS below 30°C

FAQs About NEOSPORIN H EAR DROPS

Q: Does NEOSPORIN H EAR DROPS cause ear damage?

A: Yes. When used for an extended period, NEOSPORIN H EAR DROPS may cause ear damage. Do not use NEOSPORIN H EAR DROPS in large quantities or large areas for prolonged periods. Contact your doctor before using it.

Q: Does NEOSPORIN H EAR DROPS cause kidney damage?

A: Yes. NEOSPORIN H EAR DROPS may cause kidney damage and should be used with caution in patients with kidney disease. Contact your doctor before using it.

Q: How to use NEOSPORIN H EAR DROPS

A: Clean and dry the affected ear with sterile cotton and inject NEOSPORIN H EAR DROPS into it as directed by your doctor. Shake well before use. It is for external use only. Do not apply to the eyes.

Q: Can I use NEOSPORIN H EAR DROPS during pregnancy?

A: No, NEOSPORIN H EAR DROPS is not recommended for use during pregnancy. Contact your doctor before using it.

Q: How does NEOSPORIN H EAR DROPS work?

A: NEOSPORIN H EAR DROPS helps to manage ear infections, where Polymyxin B is an antibacterial that works by damaging the cell membrane of bacteria (which is essential for their survival), leading to death. Neomycin is an aminoglycoside antibiotic that works by inhibiting protein synthesis, causing cell death. Hydrocortisone is a steroid that blocks the production of certain chemical messengers called prostaglandins (which are responsible for pain, inflammation and allergy). They effectively manage ear infections when used together.

References

1. KD Tripathi. Antimicrobial drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 760, 750, 759.

2. Casper Pharma LLC. Polymyxin B, Neomycin and Hydrocortisone. [Revised in December 2017] [Accessed on 13th July 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/060613s013lbl.pdf

3. RPK Pharmaceuticals, Inc. Polymyxin B, Neomycin and Hydrocortisone. [Revised in December 2020] [Accessed on 13th July 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=2b1b7fdf-bbcf-47dc-9e27-5ddf0e14ba83

4. Proficient Rx LP. Polymyxin B, Neomycin and Hydrocortisone. [Revised in April 2019] [Accessed on 13th July 2022] https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=d55f1783-9c49-4f90-9ff8-6f132e7b325e&type=pdf

5. Bausch & Lomb Incorporated. Polymyxin B, Neomycin and Hydrocortisone. [Revised in August 2020] [Accessed on 13th July 2022] https://www.bausch.com/contentassets/2914df881e4344a7a202cc5a0673c977/neomycin-and-polymyxinb-sulfates-and-hydrocortisone-otic-solution.pdf/

Author Details

Written By Dr. Dhivakaran R - BDS

Reviewed For Accuracy By Dr. Purvi Raghuvanshi - MBBS, ENT

Last updated on 02 Jan 2023 | 06:05 PM(IST)