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Introduction About NEOSORLEN T LOTION
NEOSORLEN T LOTION contains Trioxsalen which belongs to the group of medicines called Photosensitizers. It is used in the management of vitiligo (a pigmentation disorder of the skin that causes loss of skin color in patches) along with ultraviolet (UV) light and to increase the tolerance of the skin from the sunlight.
Trioxsalen works by photosensitization of the skin when exposed to UV or sunlight which is converted to its active metabolite to produce a beneficial reaction affecting the diseased tissue (reduces the abnormal cells and re-pigments the discolored skin).
After photoactivation it creates cross-links in DNA, which can cause programmed cell death. Your doctor may recommend you take relevant tests to understand your existing condition.
Before using NEOSORLEN T LOTION inform your doctor if you have had an allergy or disease condition. Consult your doctor for advice.
Safety and effectiveness of NEOSORLEN T LOTION in pregnant, breastfeeding women and children has not been established yet. Consult your doctor before using.
The most common side effects are erythema (skin redness), blisters on skin, edema (swelling), itching. Consult your doctor or visit a nearby hospital if you experience any unusual symptoms.
Uses Of NEOSORLEN T LOTION
- Used to manage vitiligo
How NEOSORLEN T LOTION Works
NEOSORLEN T LOTION works by photosensitization of the skin when exposed to UV or sunlight which reduces the abnormal cells and re-pigments the discolored skin. As a result, it manages depigmented skin.
How to use NEOSORLEN T LOTION
Always use NEOSORLEN T LOTION as directed by your physician. It is for external use only. Apply a thin layer of this medicine to the affected area. Your doctor will decide the right dose and duration for you depending on your age and disease condition.
Side Effects Of NEOSORLEN T LOTION
Common
- erythema (skin redness)
- blisters on skin
- edema (swelling), itching
Rare
Stop using NEOSORLEN T LOTION and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reaction
Warning & Precautions
Pregnancy
Safety and effectiveness of NEOSORLEN T LOTION in pregnant women or women planning to have a baby has not been established yet. Consult your doctor before use.
Breastfeeding
Safety and effectiveness of NEOSORLEN T LOTION in breastfeeding mothers has not been established yet. Consult your doctor for advice.
Allergy
Do not use NEOSORLEN T LOTION if you are allergic to Trioxsalen or any other ingredients of this medicine.
Others
Use in pediatrics:
Safety and effectiveness of NEOSORLEN T LOTION in children has not been established yet. Consult your doctor for advice.
Interactions
A. Drug-Drug interactions:
Before using NEOSORLEN T LOTION, inform your doctor if you are taking or using any medicines, with prescription, non-prescription or herbal medicines.
Overdosage:
If you or anyone else accidentally applied more of NEOSORLEN T LOTION, contact your doctor immediately or visit a nearby hospital immediately if the symptoms worsen.
Synopsis
| Drug | : | Trioxsalen |
| Pharmacological Category | : | Photosensitizers |
| Therapeutic Indication | : | Vitiligo |
| Dosage Forms | : | Tablet, Lotion, Cream |
More Information
- Keep out of reach from children
- Store at room temperature
FAQs About NEOSORLEN T LOTION
What is NEOSORLEN T LOTION used for?
It is used in the management of vitiligo (a pigmentation disorder of the skin that causes loss of skin color in patches) along with ultraviolet (UV) light and to increase the tolerance of the skin from the sunlight.
How does [GBNKWYORD] works?
NEOSORLEN T LOTION works by photosensitization of the skin when exposed to UV or sunlight which reduces the abnormal cells and re-pigments the discolored skin. As a result, it manages depigmented skin.
How to use NEOSORLEN T LOTION?
Always use NEOSORLEN T LOTION as directed by your physician. It is for external use only. Apply a thin layer of this medicine to the affected area. Consult your doctor for more information.
Can NEOSORLEN T LOTION cause side effects?
Yes. NEOSORLEN T LOTION can cause include itching, irritation and nausea, blistering, redness, rash and swelling, dizziness, if any of the above side effects worsen consult your doctor immediately.
Is NEOSORLEN T LOTION used along with UV light?
Yes. NEOSORLEN T LOTION is used along with UV light to manage vitiligo (a pigmentation disorder of the skin that causes loss of skin color in patches). With the help of UV light NEOSORLEN T LOTION activates itself and enhances cell death.
References
1. KD. Tripathi. Miscellaneous drugs. Essentials of medical pharmacology. 8th Edition. 2019. Page – 950.
2. O P Salo, A Lassus, J Taskinen. NIH National Library of Medicine, National center for biotechnology information. Trioxsalen bath plus UVA treatment of psoriasis. Plasma concentration of the drug and clinical results. Pubmed.gov 1981. [Accessed on 23rd July 2022] https://pubmed.ncbi.nlm.nih.gov/6177169/
3. M Hannuksela, J Karvonen. NIH National Library of Medicine, National center for biotechnology information. Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. Pubmed.gov December 1978. [Accessed on 23rd July 2022] https://pubmed.ncbi.nlm.nih.gov/737133/
4. DrugBank. Trioxsalen. [Revised on September 2007] [Accessed on 23rd July 2022] https://go.drugbank.com/drugs/DB04571
5. Canbro healthcare. Tribel. (Trioxsalen 0.2%). [Accessed on 23rd July 2022] https://www.canbro.in/product/trioxsalen-0-2
6. Albatross pharma. Trioxen lotion. (Trioxsalen 0.2%). [Accessed on 23rd July 2022] http://www.albatrosspharma.com/PDFs/Trioxen.pdf
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