Neon Laboratories Ltd

Neomol 250mg Suppository 5'S

Fever
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    Introduction About NEOMOL 250MG SUPPOSITORY

    NEOMOL 250MG SUPPOSITORY contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used to manage pain and fever (high temperature) in children (from 3 months to 12 years of age) who finds it difficult to take the medicine orally.                                 

    Before administering NEOMOL 250MG SUPPOSITORY to your child, inform child’s doctor if your child has liver or kidney problems or any allergies. Do not give your child medicines containing alcohol. Consult your child’s doctor for advice.   

    NEOMOL 250MG SUPPOSITORY is not recommended for use in elderly patients, pregnant and breast-feeding women as it is used only in children.  

    The most common side effect of using NEOMOL 250MG SUPPOSITORY is redness or soreness in and around the back passage. Consult your child’s doctor if any of the side effects get worse.   

    Uses Of NEOMOL 250MG SUPPOSITORY

    • Manage pain and fever in children (from 3 months to 12 years of age), who finds it difficult to take the medicine orally

    How NEOMOL 250MG SUPPOSITORY Works

    NEOMOL 250MG SUPPOSITORY relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating and loss of body heat.  

    How to use NEOMOL 250MG SUPPOSITORY

    Administer NEOMOL 250MG SUPPOSITORY to your child as advised by the physician. It is for rectal use only. Your child’s bowel needs to be empty when you administer it. Wash your hands and peel the wrapping apart. Do not break the medicine before use. Smoothly push into back passage of the child with the pointed end first. Slightly warm it between your hands beforehand to make it easier. Tell your child to keep still for a minute or two and then clean your hands.

    Your child’s doctor will decide the correct dose and duration for your child based upon child’s age, body weight and disease condition.  

    Side Effects Of NEOMOL 250MG SUPPOSITORY

    Common

    • redness or soreness in and around the back passage

    Rare

    • blood problems (bruising or bleeding more easily than usual, more susceptibility to infections, fever, ulcers in the mouth and throat)
    • liver problems (yellow skin or whites of the eyes)

    Stop administering NEOMOL 250MG SUPPOSITORY to your child and contact doctor immediately if your child experiences any of the following side effects:

    • allergic reaction (signs include rash, trouble swallowing or breathing, swelling of the lips, face, throat or tongue) 

    Warning & Precautions

    Pregnancy

    Contraindicated

    NEOMOL 250MG SUPPOSITORY is not recommended for use in pregnant women as it is used only in children. Consult your doctor for advice.

    Breastfeeding

    Contraindicated

    NEOMOL 250MG SUPPOSITORY is not recommended for use in breast-feeding women as it is used only in children. Consult your doctor for advice.  

    Alcohol

    Consult your doctor

    Do not give your child medicines containing alcohol. Consult child’s doctor for advice before administering NEOMOL 250MG SUPPOSITORY to your child.

    Kidney

    Use with Caution

    NEOMOL 250MG SUPPOSITORY should be used with caution in children with kidney problems. Consult your child’s doctor for advice.    

    Liver

    Use with Caution

    NEOMOL 250MG SUPPOSITORY should be used with caution in children with liver problems. Consult your child’s doctor for advice.  

    Allergy

    Contraindicated

    Do not administer NEOMOL 250MG SUPPOSITORY to your child if they are allergic to Paracetamol, soya, peanuts or any other ingredients of this medicine.

    Others

    Before administering NEOMOL 250MG SUPPOSITORY to your child, inform the doctor if your child:

    • have sepsis (circulation of bacteria and their toxins in the blood leading to organ damage)
    • are malnourished

    Use in pediatrics:

    NEOMOL 250MG SUPPOSITORY can be used in children (from 3 months of age to 12 years of age). Your child’s doctor may adjust the dose depending upon child’s age and body weight. Consult your child’s doctor for advice.  

    Use in geriatrics:

    NEOMOL 250MG SUPPOSITORY is not recommended for use in elderly patients as it is used only in children. Consult your doctor for advice.     

    Interactions

    A. Drug - Drug interactions:

    Before administering NEOMOL 250MG SUPPOSITORY to your child, inform to child’s doctor if your child is taking any of the following medicines:   

    • other medicines containing paracetamol
    • medicines used to manage nausea and vomiting (Ex. metoclopramide, domperidone)
    • cholestyramine (used to control blood lipid levels)
    • medicines used to manage fits (Ex. carbamazepine, phenytoin)
    • warfarin (used for managing blood clots)
    • medicines containing alcohol
    • medicines used to manage bacterial infections (Ex. rifampicin, flucloxacillin)

    Overdosage:

    If you have administered more NEOMOL 250MG SUPPOSITORY to your child accidentally, consult child’s doctor immediately or visit the nearby hospital, even if the child feels well, as it can cause delayed serious liver damage.

    Synopsis

    Drug :   Paracetamol
    Pharmacological Category :   Para aminophenol derivative
    Therapeutic Indication :   Pain, Fever
    Dosage Forms :  

    Tablet, Dispersible tablet, Drops, Syrup, Oral suspension, Liquid, Oral solution, Suppositories, Infusion, Injection

    More Information

    • Keep NEOMOL 250MG SUPPOSITORY out of reach of children
    • Store NEOMOL 250MG SUPPOSITORY below 25°C

    FAQs About NEOMOL 250MG SUPPOSITORY

    Q: How does NEOMOL 250MG SUPPOSITORY work?

    A: NEOMOL 250MG SUPPOSITORY relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating, and loss of body heat.

    Q: What is NEOMOL 250MG SUPPOSITORY used for?

    A: NEOMOL 250MG SUPPOSITORY contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used to manage pain and fever (high temperature) in children (from 3 months to 12 years of age) who finds it difficult to take the medicine orally.   

    Q: How to administer NEOMOL 250MG SUPPOSITORY to my child?

    A: Administer NEOMOL 250MG SUPPOSITORY to your child as advised by the physician. It is for rectal use only. Your child’s bowel needs to be empty when you administer it. Wash your hands and peel the wrapping apart. Do not break the medicine before use. Smoothly push into back passage of the child with the pointed end first. Slightly warm it between your hands beforehand to make it easier. Tell your child to keep still for a minute or two and then clean your hands.       

    Q: What happens if I accidentally administer extra dose of NEOMOL 250MG SUPPOSITORY to my child?

    A: If you have administered more NEOMOL 250MG SUPPOSITORY to your child accidentally, consult child’s doctor immediately or visit the nearby hospital, even if the child feels well, as it can cause delayed serious liver damage.

    Q: Is NEOMOL 250MG SUPPOSITORY safe to use in children with liver problems?

    A: NEOMOL 250MG SUPPOSITORY should be used with caution in children with liver problems. Child’s doctor may monitor the liver function test before and during management with this medicine to manage the risk of liver damage. Consult your child’s doctor for advice before administering NEOMOL 250MG SUPPOSITORY to your child.

    References

    1. Tilo Grosser, Emer Smyth and Garret A. FitzGerald. Anti-inflammatory, Antipyretic and Analgesic agents; Pharmacotherapy of gout. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 693.

    2. Cullen, S., Kenny, D., Ward, O. C., and Sabra, K. Paracetamol suppositories: a comparative study. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. June 1989 [Accessed on 11th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1792788/pdf/archdisch00669-0096.pdf

    3. Anderson BJ. Paracetamol (Acetaminophen): mechanisms of action. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. October 2008. [Accessed on 11th August 2022] https://pubmed.ncbi.nlm.nih.gov/18811827/#:~:text=Paracetamol%20has%20a%20central%20analgesic,active%20metabolite%20influencing%20cannabinoid%20receptors

    4. Dr. Pfleger Arzneimittel GmbH. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 11th August 2022] https://www.medicines.org.uk/emc/files/pil.8081.pdf

    5. P.P.F.Hasco-Lek SA. Health Products Regulatory Authority (HPRA). [Revised in May 2022] [Accessed on 11th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/1e4e0177-c592-42ba-a4ae-9765eeb10293.pdf

    6. Dr. Pfleger Arzneimittel GmbH. Paracetamol 125 mg Suppositories. [Revised in April 2022] [Accessed on 11th August 2022] https://www.typharm.com/wp-content/uploads/2022/06/Paracetamol-125mg-Supps-Currently-Approved-Leaflet_29_04_22.pdf

    Useful Diagnostic Tests

    • Complete blood count
    • Liver function test

    Author Details

    Written By Dr. R. Dinesh John Rajkumar - Pharm.D
    Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)
    Last updated on 28 Jan 2023 | 02:07 PM(IST)
    Lab updated