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Introduction About NEFROSAVE
NEFROSAVE is a combination of N-Acetylcysteine and Taurine which belongs to the group of medicines called Renoprotectives and Amino acids. It is used to manage diabetic kidney disease, paracetamol poisoning and radiocontrast induced kidney damage.
It protects the kidneys from damage and reduces the risk of kidney failure. Diabetic kidney disease is caused by diabetes or an increase in blood sugar, which leads to damage to the kidney.
Before taking NEFROSAVE, inform your doctor if you have lung or kidney problems, atopy (problem with your immune system that makes you more likely to develop allergic diseases), acute flushing and erythema.
NEFROSAVE is not recommended for use in pregnant and breast-feeding women unless clearly advised by the doctor. The most common side effects of taking NEFROSAVE are nausea, vomiting, flushing, rash and mouth sores. Consult your doctor if any of the side effects worsen.
Uses Of NEFROSAVE
Manages,
- Diabetic kidney disease
- Paracetamol poisoning
- Radiocontrast induced kidney damage
How NEFROSAVE Works
NEFROSAVE works by slowing down the process of the damage of the kidney cells and accordingly improves kidney functioning. It also helps in forestalling the disintegration of some microalbuminuria in diabetic kidney infections. In paracetamol poisoning it manages deterioration of microalbuminuria and enhances non-toxic sulfate conjugation of paracetamol.
How to use NEFROSAVE
Take NEFROSAVE as advised by your physician. Swallow NEFROSAVE with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of NEFROSAVE
Common
- nausea, vomiting
- rash, fever
- mouth sores, runny nose
- edema
- flushing
How To Manage Side Effects
Nausea and vomiting:
Stick to simple meals. Avoid eating oily, fried and spicy foods. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom does not improve.
Skin rash:
Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin. Consult your doctor if the symptom worsens.
Warning & Precautions
Pregnancy
NEFROSAVE is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
Breastfeeding
NEFROSAVE is not recommended for use in breastfeeding women unless considered clearly necessary. Consult your doctor before taking it.
Alcohol
Avoid consumption of alcohol during management with this medicine.
Kidney
NEFROSAVE should be used with caution in patients with kidney disease. Consult your doctor before taking it.
Allergy
Do not take NEFROSAVE if you are allergic (hypersensitive) to Acetylcysteine or Taurine.
Lungs
NEFROSAVE is not recommended for use in patients suffering from a severe and sudden attack of asthma. Patients with asthma will be monitored closely during management with this medicine.
Others
Before taking NEFROSAVE, inform your doctor if you:
- have atopy (problem with your immune system that makes you more likely to develop allergic diseases)
- have acute flushing and erythema
Interactions
A. Drug-Drug Interactions:
Before taking NEFROSAVE inform to your doctor, if you are taking any of these medicines:
- antitussives such as dextromethorphan, levodropropizine (used to manage or manage cough)
- oral antibiotics such as azithromycin, amoxicillin (used to manage bacterial infections)
Overdosage:
If you or anyone else accidentally takes too much of NEFROSAVE, consult your doctor immediately or go to a nearest hospital straight away.
Synopsis
| Drug | : | N-Acetylcysteine, Taurine |
| Pharmacological Category | : | Renoprotectives, Organosulfonic acids |
| Therapeutic Indication | : | Manages diabetic kidney disease, paracetamol poisoning and radiocontrast induced kidney damage |
| Dosage Forms | : | Tablet |
More Information
- Keep the medicine out of reach of children
- Store at room temperature
FAQs About NEFROSAVE
Q: What is NEFROSAVE used for?
A: NEFROSAVE contains n-Acetylcysteine and taurine, which is used to manage diabetic kidney disease, radiocontrast induced kidney damage and paracetamol poisoning. Consult your doctor before taking it.
Q: How does NEFROSAVE work?
A: NEFROSAVE works by slowing down the process of the damage of the kidney cells and accordingly improves kidney functioning. It also helps in forestalling the disintegration of some microalbuminuria in diabetic kidney infections. In paracetamol poisoning it manages deterioration of microalbuminuria and enhances non-toxic sulfate conjugation of paracetamol.
Q: What if I forget to take a dose of NEFROSAVE?
A: If you have missed a dose of NEFROSAVE, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one.
Q: Can NEFROSAVE be used in patients with lung problems?
A: NEFROSAVE is not recommended for use in patients suffering from a severe and sudden attack of asthma. Patients with asthma will be monitored closely during management with this medicine. Consult your doctor before taking it.
Q: Can NEFROSAVE be used in pregnant and breast-feeding women?
A: NEFROSAVE is not recommended for use in pregnant and breast-feeding women unless clearly advised by the doctor. Consult your doctor before taking this medicine if you are pregnant, planning to get pregnant or breast-feeding your child.
References
1. V. Viswanathan, M. B. Nair and P. Tilak. Effect of taurine and acetylcysteine in attenuating microalbuminuria in type 2 diabetes: Indian journal of Nephrology. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. April 2008 [Accessed on 13th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813118/
2. Akhilesh Kumar Singh, Prabhat Agarwal and Saurabh Kaushik. Study To Compare The Therapeutic Efficacy Of N-Acetyl Cysteine And Combination Of N-Acetyl Cysteine And Taurine In Proteinuria In Diabetic Nephropathy. Asian Journal of Pharmaceutical and Clinical Research. February 2017. [Accessed on 13th January 2023] https://innovareacademics.in/journals/index.php/ajpcr/article/view/15369
3. Hospimax. Alycysta (N-Acetylcysteine and Taurine). [Accessed on 13th January 2023] http://www.hospimax.com/formulation/Alcysta%20website%20content.pdf
4. Kabir Lifesciences. ACETA-N 500 (N-Acetylcysteine & Taurine Tablets). [Accessed on 13th January 2023] https://www.kabirlifescience.com/product/aceta-n
5. Alniche Life Sciences Pvt. Ltd. Renosave Tablet (Acetyl Cysteine + Taurine). [Accessed on 13th January 2023] https://www.alniche.com/product/renosave/
Useful Diagnostic Tests
- Glycosylated Hemoglobin
- Kidney Function Test
- Microalbumin Random
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