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Introduction About NEFO P TABLET
NEFO P TABLET is used for pain management associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It can also be used to reduce pain caused due to sprains, strains, sports injuries, tendon pain, bone fracture pain and minor surgical and other pains. It is a combination of Aceclofenac + Paracetamol which are pain relieving agents.
Take NEFO P TABLET after food to avoid gastric irritation. Do not take this medicine more than the duration recommended by your doctor. Before taking this medicine inform your doctor if you are having any liver, kidney or heart problems. You must also inform your doctor if you have stomach ulcers, gut inflammation, inflammatory bowel diseases or chronic alcoholism, or if you are pregnant or breastfeeding as a precaution.
The most common side effects of taking NEFO P TABLET are indigestion, stomach pain, bloating and headache which can be managed by taking this medicine with meals and by following simple diet with less spicy food and limiting alcohol consumption.
Uses Of NEFO P TABLET
Pain management associated with inflammatory bowel conditions:
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Sprains, Strains, tendon pain, bone fracture pain
- Minor surgical and other pains
How NEFO P TABLET Works
NEFO P TABLET contains aceclofenac and paracetamol which works together to relieve pain and inflammation. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks enzymes called cyclooxygenase (COX) enzymes, reducing the production of chemicals called prostaglandins, which are responsible for causing pain and inflammation.
Paracetamol, on the other hand, works by reducing the perception of pain in the brain and also helps lower fever by acting on the heat-regulating centers in the brain. Together, they provide stronger pain relief and reduce inflammation.
How to use NEFO P TABLET
- NEFO P TABLET should be taken as directed by your doctor.
- Typically, they are taken orally with water, preferably after food to avoid stomach upset.
- The usual dose is one tablet 1-2 times a day, depending on the condition being treated and your doctor's instructions.
- Do not exceed the prescribed dose, and follow the timing as recommended for the best results.
- Always consult your doctor for personalized advice on dosage and duration.
Side Effects Of NEFO P TABLET
Common Side Effects of NEFO P TABLET:
- Indigestion, abdominal pain, nausea, constipation
- headache
- dizziness
- drowsiness
- mouth ulcers
Stop taking NEFO P TABLET and consult your doctor immediately if you experience any of the following side effects:
- gastrointestinal ulceration and bleeding
- signs of low blood sugar
Warning & Precautions
Pregnancy
Consult your doctorNEFO P TABLET should be used in pregnant women only after consulting your doctor.
Breastfeeding
Consult your doctorNEFO P TABLET should be used in breastfeeding women only after consulting your doctor.
Driving and Using Machines
Use with CautionDo not take NEFO P TABLET while driving or operating machines since it may cause blurred vision, dizziness and/or drowsiness.
Kidney
Consult your doctorNEFO P TABLET is not recommended for use in patients with kidney problems such as severely impaired renal organ function. It should be used with caution in patients with kidney problems such as mild hepatic impairment.
Liver
ContraindicatedNEFO P TABLET is not recommended for use in patients with liver problems such as severely impaired hepatic function.
Allergy
ContraindicatedDo not take NEFO P TABLET if you are allergic (hypersensitive) to aceclofenac, paracetamol and/or other ingredients of this medicine.
Lungs
ContraindicatedNEFO P TABLET is not recommended for use in patients with lung problems such as asthma, bronchospasm.
Heart Disease
ContraindicatedNEFO P TABLET is not recommended for use in patients with heart problems such as severe heart failure.
Use In Pediatrics
Consult your doctorNEFO P TABLET should be used in children aged above 6 years after doctor consultation. It is not suitable for use in children aged below 6 years due to lack of safety data.
Use In Geriatrics
Use with CautionNEFO P TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking this medicine.
Others
Before taking NEFO P TABLET, inform your doctor if you:
- a history of gastrointestinal ulceration (stomach ulcer)
- have inflammatory bowel disease like (ulcerative colitis /Crohn’s disease)
- bleeding diathesis (increased susceptibility of bleeding/bruising)
- haematological abnormalities
Interactions
A. Drug-Drug interactions:
Before taking NEFO P TABLET, inform your doctor if you are taking any of the following medicine:
- other analgesics such as aspirin, cyclooxygenase-2 selective inhibitors (Ex. celecoxib, valdecoxib)
- anti-hypertensives (Ex. atenolol, propranolol)
- diuretics (Ex. hydrochlorothiazide, furosemide)
- cardiac glycosides (Ex. digoxin, digitoxin)
- lithium (medicine used to manage depression)
- methotrexate (medicine used to manage cancer)
- mifepristone (used for abortion)
- corticosteroids (Ex. prednisone, dexamethasone)
- anti-coagulants (Ex. Warfarin)
- quinolone antibiotics (Ex. ciprofloxacin, levofloxacin)
- antiplatelets (Ex. Warfarin)
- Antidepressants (such as citalopram, dapoxetine, escitalopram, fluoxetine)
- cyclosporin (used to manage organ rejection after transplantation)
- tacrolimus (used to manage moderate to severe atopic dermatitis)
- zidovudine (used to manage HIV)
- anti-diabetic agents (such as glipizide, glyburide)
- cholestyramine (used to manage high cholesterol level)
- metoclopramide, domperidone (used to manage nausea and vomiting)
- chloramphenicol (used to manage serious bacterial infections)
Overdosage:
If you or anyone else accidentally takes too much of NEFO P TABLET, consult your doctor immediately.
Synopsis
| Drug | : | Aceclofenac and Paracetamol |
| Pharmacological Category | : | Non-steroidal Anti-inflammatory drugs |
| Therapeutic Indication | : | Pain Relief |
| Dosage Forms | : | Tablet, Oral suspension, Suspension, Syrup |
More Information
FAQs About NEFO P TABLET
Q: What is NEFO P TABLET used for?
A: NEFO P TABLET is used for pain management associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It can also be used to reduce pain caused due to sprains, strains, sports injuries, tendon pain, bone fracture pain and minor surgical and other pains.
Q: How NEFO P TABLET works?
A: NEFO P TABLET is a combination of Aceclofenac and Paracetamol as active ingredients. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAIDs). It works by inhibiting the production of certain chemicals in the body, specifically prostaglandins. Prostaglandins are substances that contribute to inflammation, pain, and fever. By reducing the production of prostaglandins, Aceclofenac helps alleviate inflammation and pain associated with conditions such as arthritis, ankylosing spondylitis, and other inflammatory disorders. Paracetamol is an analgesic and antipyretic. It works by inhibiting the production of prostaglandins in the brain. While the exact mechanism is not fully understood, it is believed that paracetamol acts centrally (in the brain) to reduce pain and fever. Unlike NSAIDs, paracetamol has little to no anti-inflammatory effect.
Q: What are the most common side effects of taking NEFO P TABLET?
A: The most common side effects of taking NEFO P TABLET are indigestion, stomach pain, bloating and headache which can be managed by taking this medicine with meals and by following simple diet with less spicy food and limiting alcohol consumption.
Q: Can I drink alcohol while taking NEFO P TABLET?
A: It's generally advisable to avoid alcohol while taking NEFO P TABLET, as it may increase the risk of certain side effects such as liver damage or gastrointestinal bleeding. Consult your healthcare provider for personalized advice.
Q: How often can I take NEFO P TABLET?
A: NEFO P TABLET is typically taken 1-2 times a day, or as directed by your healthcare provider. Do not exceed the recommended dosage or frequency of administration unless advised by a healthcare professional.
Q: Is NEFO P TABLET habit-forming?
A NEFO P TABLET is not known to be habit-forming when used as prescribed. However, it's important to follow the recommended dosage and duration of management to minimize the risk of dependence or misuse.
Q: Can NEFO P TABLET be taken with food?
A: Yes, NEFO P TABLET can be taken with food or after meals to reduce the risk of stomach irritation. However, if you experience any stomach upset despite taking it with food, consult your healthcare provider.
Q: Can NEFO P TABLET be taken for a toothache?
A: NEFO P TABLET can be used for dental pain, including toothaches, as it contains Aceclofenac and Paracetamol, which provide pain relief. However, it's important to consult a dentist to determine the underlying cause of the toothache and appropriate management.
References
1. KD Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 204, 206.
2. Anil Pareek, Nitin Chandurkar, V D Sharma, Mohan Desai, Seema Kini, Girish Bartakke. A randomized, multicentric, comparative evaluation of aceclofenac-paracetamol combination with aceclofenac alone in Indian patients with osteoarthritis flare-up. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. April 2009. [Accessed on 22nd October 2024] click here
3. Taj Life Sciences. Aceclofenac and Paracetamol 100/325mg. [Accessed on 22nd October 2024] click here
4. Taj Life Sciences. Aceclofenac and Paracetamol 100/500mg. [Accessed on 22nd October 2024] click here
5. Aceclofenac and Paracetamol Tablets. Summary of Product Characteristics. [Accessed on 22nd October 2024] click here
6. Lifecare Neuro Products. Ano-Plus. Aceclofenac and Paracetamol Tablet. [Accessed on 22nd October 2024] click here
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