Nafodil 25mg Tablet 10'S

Introduction About NAFODIL

NAFODIL contains Naftopidil, which belongs to a group of medicines called Alpha-1 adrenoreceptor antagonist. It is used in men for the management of dysuria (painful urination) associated with benign prostatic hyperplasia. An enlarged prostate gland can lead to uncomfortable urinary symptoms, such as blocking the flow of urine out of the bladder, urinary tract infections or kidney problems.

NAFODIL is not recommended for use in women, patients with orthostatic hypotension (low blood pressure on standing up) or salt imbalance. NAFODIL is not recommended for use in pregnant and breastfeeding women.

NAFODIL is contraindication in children. The most common side effects of taking NAFODIL are lightheadness, dizziness, upset stomach, low blood pressure, nausea or vomiting. Consult your doctor if any of these symptoms gets worse.

Uses Of NAFODIL

• It is used in men for the management of dysuria (painful urination) associated with benign prostatic hyperplasia

How NAFODIL Works

NAFODIL reduces the prostate pressure and obstruction in the bladder hence causing relaxation of the smooth muscle in and around the prostate, which improves urine flow in patients with benign prostatic hyperplasia.

How to use NAFODIL

Take NAFODIL as advised by your physician. Swallow NAFODIL with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight.

Side Effects Of NAFODIL

How To Manage Side Effects

Nausea or vomiting:

Stick to simple meals. Avoid eating oil rich or spicy foods. Keep yourself hydrated. Consult your doctor immediately if your symptoms do not improve.

Warning & Precautions

Pregnancy

NAFODIL is not intended for use in women. Consult your doctor.

Breastfeeding

NAFODIL is not intended for use in women. Consult your doctor.

Driving and Using Machines

Do not drive or operate any machines if you feel dizzy or uneasy after taking NAFODIL.

Allergy

Do not take NAFODIL if you are allergic to Naftopidil or any other ingredients of this medicine.

Interactions

A. Drug-Drug Interactions:

Before taking NAFODIL inform your doctor if you are taking any of the following medicines:

• indapamide and its analogues (to manage high blood pressure or remove excess fluid from body)

Overdosage:

If you or anyone else accidentally takes too much of NAFODIL, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep the medicine out of reach in children
• Store NAFODIL at room temperature

FAQs About NAFODIL

Q: How does NAFODIL work?

A: NAFODIL causes relaxation of the smooth muscle in and around the prostate and improves urine flow in patients with benign prostatic hyperplasia. Consult your doctor for more information.

Q: Can NAFODIL cause low blood pressure?

A: Yes NAFODIL can cause low blood pressure on standing up so do not wake up suddenly from bed during morning. It can cause fall accidents. Wakeup, sit and stand gradually after five to ten minutes after wakeup.

Q: What is NAFODIL used for?

A: NAFODIL is used in men for the management of dysuria (painful urination) associated with benign prostatic hyperplasia. An enlarged prostate gland can lead to uncomfortable urinary symptoms, such as blocking the flow of urine out of the bladder, urinary tract infections or kidney problems.

Q: What side effects are seen with NAFODIL?

A: Like all medicines, NAFODIL can cause side effects, although not everybody gets them. The most common side effects of taking NAFODIL are nausea, vomiting, dizziness, abdominal pain, tachycardia (fast heartbeat), low blood pressure. Consult your doctor if any of these symptoms gets worse.

Q: When is NAFODIL contraindicated?

A: NAFODIL is not recommended for use in women, patients with orthostatic hypotension (low blood pressure on standing up) or salt imbalance. Consult your doctor for advice.

References

1. KD. Tripathi. Adrenergic System and Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 124- 140.

2. Hideki Kanda, Kenichiro Ishii, Yuji Ogura, Tetsuya Imamura, Masahiro Kanai, Kiminobu Arima, Yoshiki Sugimura. Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest. NIH. National Library of Medicine, National centre for biotechnology information. Pubmed.gov. January 2008. [Accessed on 20th July 2022] Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest - PubMed (nih.gov)

3. Eu Chang Hwang, Shreyas Gandhi, Jae Hung Jung, Mari Imamura, Myung Ha Kim, Ran Pang, Philipp Dahm. Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia. NIH. National Library of Medicine, National centre for biotechnology information. Pubmed.gov. October 2018. [Accessed on 20th July 2022] Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia - PubMed (nih.gov)

4. Naftopidil. CDSCO. [Revised in August 2010] [Accessed on 20th July 2022] CDSCO (cdscoonline.gov.in)

5. Drugs update. Naftopidil. [Accessed on 20th July 2022] Naftopidil drug information | DrugsUpdate India

6. MIMS. Naftopidil. [Accessed on 20th July 2022] Naftopidil: Indication, Dosage, Side Effect, Precaution | MIMS Singapore

7. Rad-ar. Naftopidil. [Accessed on 20th July 2022] Naftopidil OD Tablets 50mg "Nichiiko" | Kusuri-no-Shiori(Drug Information Sheet) (rad-ar.or.jp)

Author Details

Written By Dr. Shruthi M R - BDS

Reviewed For Accuracy By Dr. Pushpraj Singh - MBBS

Last updated on 10 Jan 2023 | 04:07 PM(IST)