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Klm Laboratories Pvt Ltd

NADITRET PLUS Cream 10gm

Skin Infections
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    Introduction About NADITRET PLUS CREAM

    NADITRET PLUS CREAM is a combination of Miconazole, Mometasone and Nadifloxacin which belongs to the group of medicines called Antifungals, Corticosteroids and Antibiotic respectively. It is used to manage bacterial and fungal skin infections like atopic and contact dermatitis, erythema multiforme, infective eczema, psoriasis and skin lesions.

    Bacterial infection occurs when bacteria enters the body, increase the number of bacteria and cause a reaction in the body. A fungal infection (mycosis) is a skin disease that is caused by a fungus when it enters the tissue. Fungal infections can be contagious and spread from one person to another person. Before using NADITRET PLUS CREAM, inform your doctor if you have psoriasis. NADITRET PLUS CREAM is not recommended for use during pregnancy.

    NADITRET PLUS CREAM should be used with caution in breastfeeding women unless considered clearly necessary. NADITRET PLUS CREAM is not recommended for use in children under 2 years of age and it should be used with caution in elderly patients. The most common side effects of this medicine are application site reactions (such as burning, irritation, itching, flaking and redness). Contact your physician if any of the above symptoms worsen.

    Uses Of NADITRET PLUS CREAM

    It is used to manage bacterial and fungal skin infections such as:

    • atopic and contact dermatitis
    • erythema multiforme
    • infective eczema
    • psoriasis
    • skin lesions

    How NADITRET PLUS CREAM Works

    NADITRET PLUS CREAM is a combination of Miconazole, Mometasone and Nadifloxacin. Miconazole works by causing holes in the cell membranes of the fungi and works against fungi. Mometasone is a corticosteroid that works by blocking the various chemical messengers (like histamine) involved in allergic and non-allergic mediated inflammation. It reduces inflammation, itchiness and redness by managing the traveling of infection-fighting white blood cells (WBCs) to the affected area of the body. Nadifloxacin belongs to antibiotic works by against the bacteria that cause skin infections and also inhibits the repairing of bacterial cells, thereby managing the further spread of the infections.

    How to use NADITRET PLUS CREAM

    Apply NADITRET PLUS CREAM as directed by your physician. It is for external use only. Apply a thin layer of the medicine to the affected area of the skin and rub it gently. Your doctor will decide the right dose depends on your age, body weight and severity of infection.

    Side Effects Of NADITRET PLUS CREAM

    Common

    • application site reactions (burning, irritation, itching, flaking and redness)

    Stop applying NADITRET PLUS CREAM and contact your physician immediately if you experience any of the following side effects:

    • severe skin reactions or allergies (swelling of the face, tongue or throat, difficulty swallowing or difficulty breathing, hives, severe irritation, reddening or blistering of the skin)
    • blurred vision or other visual disturbances

    How To Manage Side Effects

    Skin rash Or Itching

    Avoid hot baths because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the itching worsens.

    Warning & Precautions

    Pregnancy

    Monitoring required

    NADITRET PLUS CREAM is not recommended for use during pregnancy unless considered clearly necessary. Contact your doctor before applying.

    Breastfeeding

    Use with Caution

    NADITRET PLUS CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through breast milk. Contact your doctor before applying.

    Driving and Using Machines

    Use with Caution

    NADITRET PLUS CREAM does not affect the ability to drive or operate any machines. Consult your doctor before using NADITRET PLUS CREAM.

    Allergy

    Contraindicated

    Do not apply NADITRET PLUS CREAM if you are allergic to Miconazole, Mometasone, Nadifloxacin or any other ingredients of this medicine.

    Use In Pediatrics

    Contraindicated

    NADITRET PLUS CREAM is not recommended for use in children under 2 years of age. Contact your doctor before using.

    Use In Geriatrics

    Use with Caution

    In elderly patients, NADITRET PLUS CREAM should be used with caution. Contact your doctor before using this medicine.

    Others

    NADITRET PLUS CREAM is not recommended for use if you have:

    • rosacea
    • acne
    • skin atrophy (thinning of the skin)
    • dermatitis around the mouth
    • perianal and genital itching
    • nappy rash
    • bacterial infections such as impetigo
    • tuberculosis (infection of the lung)
    • syphilis (a sexually transmitted disease)
    • viral infections (shingles, warts and chickenpox)
    • fungal infections
    • parasitic infections
    • cold sores
    • shingles
    • ulcerated skin
    • wounds
    • other skin infections
    • recently had a reaction to a vaccination

    Interactions

    A. Drug-Drug interactions:

    Before using NADITRET PLUS CREAM, inform your doctor if you are taking any of the following medicine:

    • medicine used to thin the blood (Ex. warfarin)

    Overdosage:

    If you or anyone else accidentally applies too much of NADITRET PLUS CREAM or if you or a child accidentally swallow the medicine, consult your doctor immediately or visit the nearby hospital.

    Synopsis

    Drug :   Miconazole, Mometasone, Nadifloxacin
    Pharmacological Category :   Antifungals, Corticosteroids, Antibiotics
    Therapeutic Indication :   Bacterial and Fungal infections        
    Dosage Forms :   Cream

    More Information

    Storage

    • Keep out of reach of children
    • Store NADITRET PLUS CREAM below 25°C

    FAQs About NADITRET PLUS CREAM

    Q: What is the use of NADITRET PLUS CREAM?

    A: NADITRET PLUS CREAM is a combination of Miconazole, Mometasone and Nadifloxacin which belongs to the group of medicines called Antifungal, Corticosteroid and Antibiotic respectively. It is used to manage bacterial and fungal skin infections like atopic and contact dermatitis, erythema multiforme, infective eczema, psoriasis and skin lesions. Consult your physician for advice before using NADITRET PLUS CREAM.

    Q: Is it safe to use NADITRET PLUS CREAM in children?

    A: NADITRET PLUS CREAM is not recommended for use in children under 2 years of age. Contact your doctor before using NADITRET PLUS CREAM.

    Q: What are the common side effects of NADITRET PLUS CREAM?

    A: The most common side effects of NADITRET PLUS CREAM are application site reactions (burning, irritation, itching, flaking and redness). Contact your physician if any of the symptoms does not improve.

    Q: How to use NADITRET PLUS CREAM?

    A: Apply NADITRET PLUS CREAM as directed by your physician. It is for external use only. Clean and dry the skin to be managed. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with the eyes, nose, mouth or inside the vagina. Do not cover or wrap or bandage the skin unless directed by the doctor.

    Q: Is NADITRET PLUS CREAM safe to use during pregnancy and breastfeeding?

    A: NADITRET PLUS CREAM is not recommended to use during pregnancy unless considered clearly necessary. It should be used with caution in breastfeeding women as it is not known whether it may pass through breast milk. Contact your doctor before applying NADITRET PLUS CREAM.

    References

    1. K.D. Tripathi. Antifungal Drugs, Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page-787-797, 886-896.

    2. Andrei Barasch & Andreea Voinea Griffin. Miconazole revisited: new evidence of antifungal efficacy from laboratory and clinical trials. Future Medicine. May 2008. [Accessed on 19th July 2022] https://www.futuremedicine.com/doi/10.2217/17460913.3.3.265

    3. Duk Han Kim, Hyun Jong Lee, Chun Wook Park, Kyu Han Kim, Kwang Hoon Lee, Byung In Ro and Sang Hyun Cho. The Clinical Efficacy of Mometasone Furoate in Multi-Lamellar Emulsion for Eczema: A Double-blinded Crossover Study. Annals of Dermatology. February 2013. [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582923/

    4. Varsha Narayanan, Salman Motlekar, Ganesh Kadhe and Seema Bhagat. Efficacy and Safety of Nadifloxacin for Bacterial Skin Infection: Results from Clinical and Post-Marketing Studies. Journal of Dermatology and Therapy. December 2014. [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257952/

    5. Hacks & Slacks Healthcare. Nanomom – MN Cream. [Accessed on 19th July 2022] https://www.hacksslackshealthcare.com/product/nanomom-mn-cream

    6. Leeford. Inc. NADIMIN M2. [Accessed on 19th July 2022] https://www.leeford.in/product/1406/nadimin-m2

    7. Yester Pharma Pvt Ltd. OANADI-MM. [Accessed on 19th July 2022] https://www.yesterpharma.com/product/oanadi-mm/

    8. CANBRO Healthcare. NADIX-M. [Accessed on 19th July 2022] https://www.canbro.in/product/nadifloxacin-10mg-mometasone-furoate-1mg-miconazole-nitrate-20mg-cr

    9. Berko Ilaç ve Kimya Sanayi A.S. Electronic Medicines Compendium (EMC). [Revised in January 2016] [Accessed on 19th July 2022] http://berkoilac.com.tr/wp-content/uploads/2018/08/aknefloks-cream-PIL-revH.pdf

    10. Glenmark Pharmacuticals Europe Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 19th July 2022] https://www.medicines.org.uk/emc/files/pil.9994.pdf

    11. Janssen - Cilag Ltd. Electronic Medicines Compendium (EMC). [Revised in August 2020] [Accessed on 19th July 2022] https://www.medicines.org.uk/emc/files/pil.1435.pdf

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Karthikeyan Rajagopal - M. Pharma, Ph.D (Pharmacology)
    Last updated on 20 Sep 2024 | 10:14 AM(IST)
    Lab updated