Myosone Plus Tablet 6'S
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Introduction About MYOSONE PLUS
MYOSONE PLUS is a combination of Eperisone and Paracetamol which belongs to the group of medicines called Muscle relaxants and Analgesics respectively. It is used to manage pain due to muscle spasm.
Avoid consumption of alcohol while taking this medicine as it may severely damage the liver. MYOSONE PLUS should be used with caution in patients with asthma, liver disease or disorder and kidney disease.
MYOSONE PLUS should be used with caution in pregnant women unless advised by the doctor and it is not recommended for use in breastfeeding women. MYOSONE PLUS is not recommended for use in children due to lack of safety data and it should be used with caution in elderly patients (aged 65 years and above).
The most common side effects of taking MYOSONE PLUS are nausea, vomiting, stomach discomfort, abdominal pain, general discomfort and constipation. Consult your doctor if any of the side effects worsen over the time.
Uses Of MYOSONE PLUS
- Manage pain due to muscle spasm
How MYOSONE PLUS Works
MYOSONE PLUS helps to manage pain due to muscle spasm, where eperisone works by acting on the centres in the brain and spinal cord. It also dilates vascular smooth muscles improving blood flow and relieves muscle spasm. Paracetamol works by increasing the pain threshold by inhibiting COX-1 and COX-2 enzymes.
How to use MYOSONE PLUS
Take MYOSONE PLUS as advised by your physician. Swallow MYOSONE PLUS with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking MYOSONE PLUS without informing your doctor.
Side Effects Of MYOSONE PLUS
Common
- nausea, vomiting
- loss of appetite, gastric discomfort
- abdominal pain
- diarrhea, constipation
- light-headedness, drowsiness
- lack of energy
- general discomfort
- rash, itching
- erythema multiforme exudativum (red and raised rash)
Rare
- depression, confusion, hallucinations
- tremor, headache
- disturbed vision
- oedema (abnormal accumulation of fluid under the skin)
- bleeding from stomach or intestines
- dizziness, fever
Stop taking MYOSONE PLUS and contact your physician immediately if you experience any of the following side effects:
- severe allergic reactions (signs include swelling of the face, lips, tongue, neck or throat causing difficulty in breathing)
- anaphylactoid symptoms (such as itchiness, edema (such as facial), respiratory distress)
- steven-johnson syndrome, toxic epidermal necrosis (signs include fever, erythema, bloodshot eyes)
How To Manage Side Effects
Constipation
Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals and drink plenty of water. Exercise regularly (such as daily walk). If this does not help, consult your doctor for receiving alternate management for constipation.
Diarrhea
Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Do not take any medicine on your own for managing diarrhoea. Consult your doctor if the symptom does not improve.
Headache
Rest and relax. Drink plenty of fluids such as water or electrolytes and apply a pain-relieving balm on the forehead if necessary. Do not consume alcohol. Consult your doctor if the symptom does not improve.
Nausea And Vomiting
Take this medicine with or immediately after food. Stick to simple meals. Avoid eating oily, fried and spicy foods. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom does not improve.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, consult your doctor.
Warning & Precautions
Pregnancy
Use with CautionMYOSONE PLUS should be used with caution during pregnancy unless considered clearly necessary. Consult your doctor before taking MYOSONE PLUS.
Breastfeeding
ContraindicatedMYOSONE PLUS is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking MYOSONE PLUS.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel weakness, sleepiness, light-headedness after taking MYOSONE PLUS.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking MYOSONE PLUS as it may severely damage the liver.
Kidney
Use with CautionMYOSONE PLUS should be used with caution in patients with kidney disease. Consult your doctor before taking MYOSONE PLUS.
Liver
Use with CautionMYOSONE PLUS should be used with caution in patients with liver disorder or disease (including Gilbert’s syndrome or hepatitis). Consult your doctor before taking MYOSONE PLUS.
Allergy
ContraindicatedDo not take MYOSONE PLUS if you are allergic to Eperisone, Paracetamol or other ingredients of this medicine.
Lungs
Use with CautionMYOSONE PLUS should be used with caution in patients with asthma. Consult your doctor before taking MYOSONE PLUS.
Others
Before taking MYOSONE PLUS, inform your doctor if you:
- are dehydrated or have impaired nutritional state (caused by alcohol abuse or wrong nutrition)
- haemolytic anaemia (abnormal breakdown of red blood cells)
- deficiency of glucose- 6-phosphatedehydrogenase enzyme
- serious infection such as blood poisoning
Use in Paediatrics:
MYOSONE PLUS is not recommended for use in children due to lack of safety data. Consult your child’s doctor for advice.
Use in geriatrics:
MYOSONE PLUS should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking MYOSONE PLUS inform your doctor if you are taking any of the following medicines:
- methocarbamol (used to manage muscle spasm)
- probenecid (used to manage gout)
- salicylamide (used to manage fever and pain)
- lamotrigine, phenytoin (used to manage epilepsy)
- barbiturates such as pentobarbital, phenobarbital or carbamazepine (medicines used to manage mental disorders and epilepsy)
- chloramphenicol, rifampicin, isoniazid (medicines used to manage bacterial infections)
- St. john’s wort (used to manage depression)
- medicines that delay emptying of stomach (Ex. dicyclomine)
- anticoagulants Ex. warfarin (medicines used to manage or manage blood clots)
- medicines used for nausea and vomiting (Ex. metoclopramide, domperidone)
- cholestyramine (medicines used to lower high cholesterol levels)
- imatinib (medicine used to manage leukaemia and some stomach tumours)
Overdosage:
If you or anyone else accidentally take too much of MYOSONE PLUS, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of MYOSONE PLUS inlcudes nausea, vomiting, loss of appetite, paleness, stomach pain and liver damage.
Synopsis
| Drug | : | Eperisone, Paracetamol |
| Pharmacological Category | : | Muscle relaxant, Analgesics |
| Therapeutic Indication | : | Pain due to muscle spasm |
| Dosage Forms | : | Tablet |
More Information
- Keep MYOSONE PLUS out of reach of children
- Store at room temperature
FAQs About MYOSONE PLUS
Q: What to do If I forget to take a dose of MYOSONE PLUS?
A: You should take MYOSONE PLUS immediately when you remember. If it is time for the next dose skip the missed dose and follow the regular dose schedule. Do not double the dose to match up the missed dose.
Q: How does MYOSONE PLUS work?
A: MYOSONE PLUS helps to manage pain due to muscle spasm, where eperisone works by acting on the centres in the brain and spinal cord. It also dilates vascular smooth muscles improving blood flow and relieves muscle spasm. Paracetamol works by increasing the pain threshold by inhibiting COX-1 and COX-2 enzymes.
Q: Is MYOSONE PLUS safe to use in patients with liver problems?
A: MYOSONE PLUS should be used with caution in patients with liver disorder or disease (including Gilbert’s syndrome or hepatitis). Consult your doctor for advice before taking it.
Q: What are the common side effects of MYOSONE PLUS?
A: The common side effects of taking MYOSONE PLUS are nausea, vomiting, loss of appetite, gastric discomfort, abdominal pain, diarrhea, constipation, light-headedness, drowsiness, general discomfort, lack of energy, rash and itching. Consult your doctor if any of the side effects worsen over the time.
Q: Does MYOSONE PLUS cause constipation?
A: Yes, this medicine may cause constipation in some individuals. To manage this effect, try to eat more high-fiber foods such as fresh fruit, vegetables, cereals and drink plenty of water. Exercise regularly (such as daily walk). If this does not help, consult your doctor for receiving alternate management for constipation.
References
1. K.D. Tripathi. NSAIDs and Antipyretic- Analgesics. Essentials of medical pharmacology. Seventh edition. 2013. Page - 206.
2. P. Cabitza, P. Randelli. Uses of Eperisone. European Review for Medical and Pharmacological Sciences. December 2008. [Accessed on 15th June 2022] http://europeanreview.org/wp/wp-content/uploads/502.pdf
3. Eperisone. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem. 2004. [Accessed on 15th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/eperisone
4. Accord, Barnstaple. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 15th June 2022] https://www.medicines.org.uk/emc/files/pil.5916.pdf
5. Balkan Pharma. Health Products Regulatory Authority (HPRA). [Revised in June 2019] [Accessed on 15th June 2022] https://www.hpra.ie/img/uploaded/swedocuments/2b04cfdb-8571-4543-a4c9-b1380e0a92c3.pdf
6. Eisai Co., Ltd. Myonal Tablet (Eperisone). [Revised in July 2009] [Accessed on 15th June 2022] http://www.shijiebiaopin.net/upload/product/201082521391314.pdf
7. Taj Pharmaceuticals. Eperisone and Paracetamol Tablet. [Accessed on 15th June 2022] https://tajpharma.in/portfolio-item/eperisone-hdrochloride-paracetamol-50mg325mg-tablets-taj-pharma/
8. Steris Healthcare Pvt Ltd. Epstate Plus Tablet (Eperisone and Paracetamol). [Accessed on 15th June 2022] https://www.sterisindia.com/latest-update/eperisone-hydrochlor/7176
9. Towa Pharmaceutical Co., Ltd. Eperisone Hydrochloride Tablets. [Revised in November 2016] [Accessed on 15th June 2022] https://www.rad-ar.or.jp/siori/english/search/result?n=34882
Useful Diagnostic Tests
- Liver function test
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