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Introduction About MYOREST TABLET
MYOREST TABLET is a combination of Chlorzoxazone and Paracetamol which belongs to the group of medicines called Muscle relaxants and Analgesics respectively. It is used to manage muscular pains and spasms. It can also be used to provide relief from joint pain (Ex. osteoarthritis, rheumatoid arthritis), back pain (Ex. ankylosing spondylitis) and neck pain.
Take MYOREST TABLET preferably with meals to avoid gut irritation. Avoid consumption of alcohol as it could aggravate the risk of stomach problems. Do not take MYOREST TABLET if you have any ulcers, bleeding or perforations in the gut.
Before taking MYOREST TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have asthma, alcoholism, any eating disorder or any disease that causes loss of skeletal muscles and fats (such as cachexia) as a precaution.
Consult your doctor before taking MYOREST TABLET if you are pregnant or breastfeeding. The common side effects of taking MYOREST TABLET are stomach upset and orangish urine. Consult your doctor if any of these side effect worsens.
Uses Of MYOREST TABLET
It is used to manage:
- Muscle pain and spasms
- Joint pain, back pain, neck pain
How MYOREST TABLET Works
MYOREST TABLET contains two medicines namely Chlorzoxazone and paracetamol. Chlorzoxazone is a muscle relaxant. It acts by increasing the effects of certain chemical messengers (such as GABA) in the brain and in spinal cord that induces muscle relaxation. As a result, it manages muscle twitching, relieves pain caused due to muscle spasms and improves muscle movement.
Paracetamol is a pain-relieving agent. It provides pain relief by blocking the release of certain chemicals (such as prostaglandins) in the body that causes pain, inflammation and swelling. Collectively, these action helps in reducing muscle spasms, joint pain and inflammation.
How to use MYOREST TABLET
Take MYOREST TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It is preferably taken with meals to avoid gastric irritation.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Side Effects Of MYOREST TABLET
Common
- Stomach upset
- Orangish or reddish urine
Rare
- drowsiness, dizziness
- tiredness, excitement
- skin rash, itching or redness
Stop taking MYOREST TABLET and consult your doctor immediately if you experience any of the following:
- signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing, chest tightness, fever, ulcers on the mucous membrane, oral sores)
- low blood counts causing increased infections and unusual bleeding or bruising
- signs of liver problem (such as fever, skin rash, lack of appetite, nausea, vomiting, fatigue, upper abdominal pain, dark urine, yellowing of skin and whites of the eye)
How To Manage Side Effects
Skin rash:
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.
Warning & Precautions
Pregnancy
MYOREST TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
Breastfeeding
MYOREST TABLET should be used in breastfeeding women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any heavy tools or machines if you experience dizziness, drowsiness or vision problems after taking MYOREST TABLET.
Alcohol
Avoid consumption of alcohol while taking MYOREST TABLET as it may increase the risk of side effects.
Kidney
MYOREST TABLET is not recommended for use in patients with moderate to severe kidney diseases. It should be used with caution in patients with mild kidney problems. Therefore, consult your doctor before taking it.
Liver
MYOREST TABLET is not recommended in patients with severe liver problems (such as liver failure). It should be used with caution in patients with mild liver problems. Therefore, consult your doctor before taking it.
Allergy
Do not take MYOREST TABLET if you are allergic to Chlorzoxazone or Paracetamol.
Lungs
MYOREST TABLET is not recommended for use in patients who previous experienced asthma attack or breathing difficulties after taking any pain-relieving medicine.
Others
MYOREST TABLET is not recommended for use if you:
- have GI bleeding (bloody stools or vomits)
- have ulcers in the stomach or intestines
Before taking MYOREST TABLET inform your doctor if you:
- are an alcoholic
- have porphyria (a rare inherited blood disorder)
- have any eating disorders
- have cystic fibrosis
- have HIV infection
- have starvation (starving without food)
- have cachexia (loss of skeletal muscles and fat)
Use in Pediatrics:
MYOREST TABLET is not recommended for use in children aged below 12 years. Therefore, consult your doctor for advice before taking it.
Use in Geriatrics:
MYOREST TABLET should be used with caution in elderly patients. Therefore, consult your doctor for advice before taking it.
Interactions
A. Drug-Drug Interactions:
Before taking MYOREST TABLET, inform your doctor if you are taking any of the following medicines such as:
- medicines used to stop blood clotting (Ex. warfarin, heparin, clopidogrel)
- cholestyramine (a medicine used to control blood cholesterol levels)
- medicines used to manage nausea and vomiting (Ex. domperidone, metoclopramide)
- medicines that can induce sleep (Ex. alprazolam, midazolam, clonazepam, nitrazepam)
- rifampicin, isoniazid (medicines used to manage tuberculosis)
- disulfiram (a medicine used to quit alcoholism)
- medicines used to manage epilepsy (such as carbamazepine, phenobarbitone, phenytoin)
- primidone (a medicine used to manage mental illnesses)
- St. John's Wort (an herbal medicine used to manage depression)
Overdosage:
If you or anyone else accidentally took more MYOREST TABLET, visit the nearby hospital or consult your doctor immediately. Symptoms of overdosage might include paleness, nausea, vomiting, loss of appetite, stomach pain, liver damage, low blood sugar levels, edema, bloody urine, loss of protein in urine, dizziness, drowsiness, headache and tiredness.
Synopsis
| Drug | : | Chlorzoxazone, Paracetamol |
| Pharmacological Category | : | Mephensin Congeners, Analgesics and Antipyretics |
| Therapeutic Indication | : | Muscle Pain, Joint Pain, Back pain |
| Dosage Forms | : | Tablet |
More Information
- Keep MYOREST TABLET out of reach of children
- Store MYOREST TABLET below 25°C
FAQs About MYOREST TABLET
What is the use of MYOREST TABLET?
MYOREST TABLET is used to manage muscular pains and spasms. It can also be used to provide relief from joint pain (Ex. osteoarthritis, rheumatoid arthritis), back pain (Ex. ankylosing spondylitis) and neck pain.
How MYOREST TABLET works?
MYOREST TABLET works by reducing pain and inflammation in the muscles and bones. It increases the effects of certain chemical messengers (such as GABA) in the brain and in spinal cord that induces muscle relaxation and blocks the release of certain chemicals (such as prostaglandins) in the body that causes pain, inflammation and swelling. Collectively, these action helps in reducing muscle spasms, joint pain and inflammation.
How to take MYOREST TABLET?
Take MYOREST TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not chew or crush the medicine. It is preferably taken with meals to avoid gastric irritation.
What is the best time to take MYOREST TABLET?
MYOREST TABLET can be taken at any time of the day. However, your doctor will decide the best time to take MYOREST TABLET.
Can I stop taking MYOREST TABLET once I started feeling better?
No. Do not stop taking MYOREST TABLET without consulting your doctor as it may make your symptoms re-appear once again. If you feel better during the midway of therapy, consult your doctor for advice.
Can I take MYOREST TABLET daily?
Take MYOREST TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take MYOREST TABLET every day or not.
Will taking a higher dose of MYOREST TABLET be more effective?
No. Taking a higher dose of MYOREST TABLET will not be effective rather it would be making you drowsier. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
What to do if I forgot to take a dose of MYOREST TABLET?
If you forgot to take a dose of MYOREST TABLET, take it as soon as you remember. However, if it is time for the next dose of MYOREST TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of MYOREST TABLET to compensate the missed ones. Consult your doctor for advice.
What are the side effects of MYOREST TABLET?
The common side effects of taking MYOREST TABLET are stomach upset and orangish urine. Consult your doctor if any of these side effect worsens.
Can I consume alcohol while taking MYOREST TABLET?
Avoid consumption of alcohol while taking MYOREST TABLET as it might make you feel dizzier and drowsier.
Can MYOREST TABLET be taken during pregnancy?
MYOREST TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
Can the use of MYOREST TABLET affect the liver?
Yes. MYOREST TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is not recommended for use in patients with liver failure. It should be used with caution in patients with other mild liver problems. Consult your doctor before taking it.
References
1. KD. Tripathi. Nonsteroidal Anti-Inflammatory Drugs and Antipyretic-Analgesics. Skeletal Muscle Relaxants. Seventh edition. Page – 206 & 357.
2. Himanshu D. Patel, R. B. Uppin, A. Ramakrishnam Naidu, Y. Ratnakar Rao, Suhas Khandarkar, and Amit Garg. Efficacy and Safety of Combination of NSAIDs and Muscle Relaxants in the Management of Acute Low Back Pain. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. January 2019. [Accessed on 24th December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513919/
3. GlaxoSmithKline. PARACETAMOL/CHLORZOXAZONE. [Accessed on 24th December 2022] https://gskpro.com/content/dam/global/hcpportal/en_TZ/PI/MYOLGIN-NCDS-v-03.pdf
4. Solubiomix, LLC. Chlorzoxazone 250 mg. Dailymed.com. [Revised in October 2022]. [Accessed on 24th December 2022] https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=c3d40a90-6df8-4b44-bc61-d7655c52bacb&type=pdf
5. Reliable 1 Laboratories LLC. Acetaminophen 325mg – Acetaminophen tablet. Dailymed.com. [Revised in October 2021]. [Accessed on 24th December 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=25626b46-78f8-7226-e054-00144ff8d46c
6. Accord. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 24th November 2022] https://www.medicines.org.uk/emc/files/pil.5916.pdf
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