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Introduction About MOXIKIND CV
MOXIKIND CV contains Amoxicillin and Clavulanic acid, which belong to the group of medicines called Penicillins and Beta-Lactamase Inhibitors. It is used in the management of various bacterial infections such as respiratory tract infections (pneumonia, acute exacerbation of chronic bronchitis), urinary tract infections (cystitis, urethritis, pyelonephritis), bone and joint infections (osteomyelitis), middle ear infections (otitis media), tonsillitis, sinusitis, skin and soft tissue infections such as cellulitis, boils, wound infections, intra-abdominal sepsis, dental infections, infections of genital organs in females.
MOXIKIND CV is also used as prophylaxis against various bacterial infections associated with major surgeries of the heart, joints, kidney, head and neck, stomach, biliary tract, intestine and pelvic region. Along with management with MOXIKIND CV your doctor might order bacterial culture tests to enhance the outcomes of the management.
MOXIKIND CV is not recommended for use in patients with severe kidney impairment, who had a history of liver problems or jaundice after taking penicillin antibiotics. Consult your doctor before receiving it. MOXIKIND CV should be used with caution in patients suffering from glandular fever (a viral infection causing sore throat, high fever, swelling of salivary glands etc.), liver disease, kidney disease, who are not passing urine daily, convulsions (fits) or large intestine inflammation.
MOXIKIND CV is not recommended for use in pregnant women unless necessary. MOXIKIND CV should be used with caution in breastfeeding women as it may pass through breast milk. MOXIKIND CV should be used with caution in children as it may require dose modification. Consult your doctor before receiving MOXIKIND CV. The most common side effects after receiving MOXIKIND CV are diarrhoea, thrush (fungal infection), etc. Consult your doctor immediately if any of your symptoms get worse or persist.
Uses Of MOXIKIND CV
- Management and prophylaxis management of various bacterial infections
How MOXIKIND CV Works
MOXIKIND CV helps in managing bacterial infection where Amoxicillin works by inhibiting penicillin-binding proteins (which are involved in the synthesis of the bacterial cell wall) leading to the activation of autolytic enzymes in the bacterial cell wall. Therefore, leading to lysis of the cell wall and death of the bacterial cell and Clavulanic acid inhibits the activity of bacterial enzymes known as beta-lactamases and hence enhances the antibacterial activity of amoxicillin.
How to use MOXIKIND CV
MOXIKIND CV will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or intravenous injection. Your doctor will decide the exact dose and duration of management for you depending on your age, body weight and disease condition.
Side Effects Of MOXIKIND CV
Common
- diarrhoea
- thrush (candida fungal infection)
Uncommon
- rashes, itching, hives (raised itch rashes)
- urticaria
- nausea and vomiting
- dizziness, headache
- indigestion
- abnormal liver enzymes
Rare
- erythema multiforme (skin rashes, blisters, small target rashes)
- low number of platelets (cells that helps in clotting)
- decreased white blood cells
- swelling and inflammation at site of injection
Stop receiving MOXIKIND CV and consult your doctor immediately in case you experience:
- severe allergic reaction which includes rashes, collapsing or fainting, swelling of the face, throat which may cause difficulty in breathing, fever, joint pain, swollen lymph nodes of neck, armpits, groin, red or purple raised spots on skin due to inflammation of blood vessels
- Swelling and tenderness of vein which is very painful on touching
- Watery diarrhoea with blood or mucus, fever and abdominal pain which occurs due to inflammation of the large intestine
- inflammation of the liver (hepatitis), jaundice (yellowing of white part of eyes, nails, skin paleness)
- inflammation of kidney tubes
- delayed blood clotting
- convulsions (fits) most commonly experienced by patients suffering from kidney disease
- severe skin reactions such as widespread rashes with blisters and peeling skin, around the mouth, nose, eyes and genitals (stevens-johnson syndrome, toxic epidermal necrolysis), widespread red skin rash with small pus-containing blisters (bullous exfoliative dermatitis), a red, scaly rash with bumps under the skin and blisters (exanthemous pustulosis)
- flu-like symptoms with a rash, fever, swollen glands, an increased number of white blood cells and abnormal liver enzymes (Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
How To Manage Side Effects
Nausea, vomiting:
Receive the medicine, before meals. Stick to simple meals. Avoid eating oily or spicy food however, contact your doctor if nausea or vomiting gets worse or persists.
Itchy skin:
Avoid hot showers because hot water can irritate the skin and do not scratch the affected area. Apply moisturizing cream, Sunscreen and use protective clothing. Contact your doctor in case the itching gets worse or persists.
Diarrhoea:
Drink plenty of water or fruit juices to keep you hydrated. Don’t take any medicine on your own for managing diarrhoea however contact your doctor if diarrhoea gets worse or persists.
Headache:
Rest and relax. Drink plenty of water and electrolytes. Apply a pain-relieving balm on the head if required. Do not consume alcohol however, contact your doctor if your headache gets worse or persists.
Warning & Precautions
Pregnancy
MOXIKIND CV is not recommended for use in pregnant women unless necessary. Consult your doctor before receiving MOXIKIND CV.
Breastfeeding
MOXIKIND CV should be used with caution in breastfeeding women as it may pass through breast milk. Consult your doctor before receiving MOXIKIND CV.
Driving and Using Machines
Do not drive or operate machinery after receiving MOXIKIND CV.
Kidney
MOXIKIND CV is not recommended for use in patients with severe kidney impairment. Consult your doctor before receiving MOXIKIND CV.
MOXIKIND CV should be used with caution in patients suffering from kidney problems. Consult your doctor before receiving MOXIKIND CV.
Liver
MOXIKIND CV is not recommended for use in patients who had a history of liver problems or jaundice after taking penicillin antibiotics. Consult your doctor before receiving MOXIKIND CV.
MOXIKIND CV should be used with caution in patients suffering from, liver disease. consult your doctor before receiving MOXIKIND CV.
Allergy
Do not receive MOXIKIND CV if you are allergic to Amoxicillin, Clavulanic acid or any other ingredients in this medicine.
Others
Before receiving MOXIKIND CV inform your doctor if you have:
- glandular fever (viral infection causing sore throat, high fever, swelling of salivary glands etc)
- not been urinating regularly
- convulsions (fits)
- large intestine inflammation
- urine and blood tests
Use in paediatrics:
MOXIKIND CV should be used with caution children as it may requires dose modification. Consult your doctor before administration of MOXIKIND CV to your child.
Use in geriatrics:
MOXIKIND CV should be used with caution in the elderly. Consult your doctor for advice.
Interactions
A. Drug-Drug interactions:
Before receiving MOXIKIND CV, inform your doctor if you are taking any of the following medicine:
- medicines used to manage gout (Ex. allopurinol, probenecid)
- medicines used to manage blood clots (Ex. warfarin)
- methotrexate (used for the management of cancer, severe psoriasis)
- medicine used to manage organ transplant rejection (Ex. Mycophenolate mofetil)
- medicines used for management of pregnancy (oral contraceptives)
Overdosage:
MOXIKIND CV will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse immediately if you experience any unusual symptoms. Symptoms of overdose of MOXIKIND CV are nausea, diarrhoea, fits, upset stomach.
Synopsis
| Drug | : | Amoxicillin + Clavulanic acid |
| Pharmacological Category | : | Penicillins and Beta-Lactamase Inhibitors |
| Therapeutic Indication | : | Bacterial Infections |
| Dosage Forms | : | Tablets, Syrup, Oral Drops, Eye Drops, Ear Drops, Oral Suspension, Injection, Dispersible Tablet, Dry Suspension, Dry Syrup, Sachet |
More Information
- Keep MOXIKIND CV out of reach from children
- Store MOXIKIND CV below 25 degrees
FAQs About MOXIKIND CV
What are the uses of MOXIKIND CV?
MOXIKIND CV is used in adults and children for the management of various bacterial infections such as respiratory tract infections which includes pneumonia, acute exacerbation of chronic bronchitis, urinary tract infections (cystitis, urethritis, pyelonephritis), bone and joint infections (osteomyelitis), middle ear infections (otitis media), tonsillitis, sinusitis, skin and soft tissue infections such as cellulitis, boils, wound infections, intra-abdominal sepsis, dental infections, infections of genital organs in females. MOXIKIND CV is also used as prophylaxis against various bacterial infections associated with major surgeries of the heart, joints, kidney, head and neck, stomach, biliary tract, intestine and pelvic region.
What are the side effects of MOXIKIND CV?
The most common side effects after receiving MOXIKIND CV are vomiting, diarrhoea, thrush (fungal infection), etc. Consult your doctor immediately in case any of the side effects worsen.
How does MOXIKIND CV work?
MOXIKIND CV helps in managing bacterial infection where Amoxicillin works by inhibiting penicillin-binding proteins (which are involved in the synthesis of the bacterial cell wall), leading to the activation of autolytic enzymes in the bacterial cell wall. Therefore, leading to lysis of the cell wall and death of the bacterial cell and Clavulanic acid inhibits the activity of bacterial enzymes known as beta-lactamases, hence enhancing the antibacterial activity of amoxicillin.
Is MOXIKIND CV safe for use in pregnant and breastfeeding women?
No, MOXIKIND CV is not recommended for use in pregnant women unless necessary and MOXIKIND CV should be used with caution in breastfeeding women as it may pass through breastmilk. Consult your doctor before receiving MOXIKIND CV.
References
1. KD Tripathi. Antimicrobial Drugs. Essentials of Medical Pharmacology. 7th edition. 2013. Page-723, 724.
2. Justin Evans, Maryam Hannoodee, Micah Wittler. Amoxicillin Clavulanate. National Centre for Biotechnology. NLM. National Institute of Health. Statpearls. December 2021. [Accessed on 21st October 2022] https://www.ncbi.nlm.nih.gov/books/NBK538164/#article-17475.s5
3. Pharmachemie B.V. Human Products and Regulatory Authority (HPRA). [Revised in October 2021] [Accessed on 21st October 2022] https://www.hpra.ie/img/uploaded/swedocuments/8b431234-1c37-4f42-b962-f92da83d33ef.pdf
4. Antibiotice SA. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 21st October 2022] https://www.medicines.org.uk/emc/files/pil.11108.pdf
5. Fresensius Kabi Limited. Human Products and Regulatory Authority (HPRA). [Revised in March 2022] [Accessed on 21st October 2022] https://www.hpra.ie/img/uploaded/swedocuments/71865a06-c147-4ab6-8563-5db6ce566a30.pdf
6. GlaxoSmithKline Pharmaceuticals Limited. Amoxicillin + Clavulanic acid. [Revised in July 2022] [Accessed on 21st October 2022] https://india-pharma.gsk.com/media/6337/augmentin-i-v.pdf
7. Medreich Limited. Amoxicillin + Clavulanic acid. [Revised in June 2015] [Accessed on 21st October 2022] http://www.paradigmpharma.com/CMS/IMAGES/pdfuploads/1503656556_Fleming%20(Co-Amoxiclav).pdf
8. Cipla Limited. Amoxicillin + Clavulanic acid. [Revised in September 2019] [Accessed on 21st October 2022] https://www.ciplamed.com/content/advent-iv-injection
9. Augpen Injection (Amoxicillin + Clavulanic acid). Zuventus Healthcare Limited. [Accessed on 21st October 2022] http://www.zuventus.co.in/doctor_wise_products_selected.aspx?Medi_Id=65
Useful Diagnostic Tests
- bacterial culture tests
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