GST Benefits New Revised MRP, 100% GST benefit passed
Cipla Ltd

Misoprost 200mcg Tablet 4'S

Ulcer/Reflux/Flatule...
MRP ₹84.98 (Inclusive of all taxes)
Deliver to

    Netmeds First Membership

    Starting at just ₹[] for 3 months.
    View Plans

    Introduction About MISOPROST 200MCG TABLET

    MISOPROST 200MCG TABLET contains Misoprostol which belongs to the group of medicines called Prostaglandin Analogs. It is used to manage peptic ulcer, predominantly caused due to excessive NSAID use (such as diclofenac, naproxen).

    It can also be used for cervical ripening (dilation) prior to certain uterine procedures and for inducing labour pain. It is also used in combination with mifepristone (an abortion pill) to induce abortion during the early stages of pregnancy (first trimester) and can manage excessive blood loss after childbirth.

    Take MISOPROST 200MCG TABLET with meals to avoid stomach upset. Avoid taking antacids (containing magnesium) along with this medicine as it may increase the risk of severe stomach problems.

    Before taking MISOPROST 200MCG TABLET inform your doctor if you previously delivered your baby via caesarean section. You must also inform your doctor if you have any heart problems, high or low blood pressure, inflammatory bowel diseases or problems in blood vessels as a precaution.

    Pregnant women should not get themselves exposed to this medicine as it may cause abortion or serious birth defects in the growing baby. It is also not suitable for use in breastfeeding women and in children aged below 18 years. Women of childbearing potential must use a suitable contraceptive method to avoid becoming pregnant while taking this medicine.

    The most common side effects of taking MISOPROST 200MCG TABLET are skin rashes, diarrhea, headache, dizziness, stomach pain, constipation, bloating, indigestion, birth defects (if accidentally exposed during pregnancy), vaginal bleeding (even after menopause) and severe uterine cramps. Consult your doctor if any of these side effects trouble you.

    Uses Of MISOPROST 200MCG TABLET

    • Manage and manages peptic ulcer, predominantly caused due to excessive NSAID use (such as diclofenac, naproxen)
    • Used for cervical ripening (prior to certain uterine procedures)
    • Used for inducing labour pain
    • Can induce abortion during the first trimester of pregnancy
    • Prevents excessive blood loss after childbirth

    How MISOPROST 200MCG TABLET Works

    MISOPROST 200MCG TABLET reduces excessive stomach acid secretion caused due to prolonged NSAIDs use. This action heals the existing ulcers, manages new ulcers formation and provides relief from the unpleasant symptoms of GI tract (such as acidity and heartburn).

    It also stimulates the contraction of uterine muscles which helps in initiating labour pain, reducing postpartum bleeding and for inducing abortion during the early stages of pregnancy. It also degrades the cells and tissues around the cervix, which helps in cervical ripening (softening) prior to uterine procedures.

    How to use MISOPROST 200MCG TABLET

    Take MISOPROST 200MCG TABLET with meals to avoid stomach upset. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

    Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

    Side Effects Of MISOPROST 200MCG TABLET

    Common

    • skin rash
    • diarrhea
    • headache, dizziness
    • stomach pain, constipation, bloating, indigestion
    • nausea, vomiting
    • birth defects (if accidentally exposed during pregnancy)

    Uncommon

    • fever
    • irregular periods, severe uterine pain
    • vaginal bleeding (among menopausal or older women)

    Rare

    Stop taking MISOPROST 200MCG TABLET and contact your doctor immediately if you experience any of the following side effects such as:

    • severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body, difficulty in breathing or swallowing, swelling of hands and legs)
    • painful, prolonged heavy menstrual bleeding, abnormal uterine contractions

     

    How To Manage Side Effects

    Dizziness Or Drowsiness

    Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

    Headache

    Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

    Nausea And Vomiting

    Take MISOPROST 200MCG TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

    Warning & Precautions

    Pregnancy

    Contraindicated

    Do not take MISOPROST 200MCG TABLET if you are pregnant, think you may be pregnant or planning to have a baby, as this medicine may cause abortion or serious birth defects in the growing baby. MISOPROST 200MCG TABLET should be used under careful medical supervision if abortion of the foetus is considered necessary by the physician. Women of childbearing potential must use a suitable contraceptive method to avoid becoming pregnant while taking this medicine. Stop taking MISOPROST 200MCG TABLET and contact your doctor immediately if you accidentally became pregnant while taking MISOPROST 200MCG TABLET.

    Breastfeeding

    Contraindicated

    MISOPROST 200MCG TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any heavy tools or machines if your ability is affected by MISOPROST 200MCG TABLET.

    Allergy

    Contraindicated

    Do not take MISOPROST 200MCG TABLET if you are allergic to Misoprostol or to any other ingredients of this medicine.

    Heart Disease

    Use with Caution

    MISOPROST 200MCG TABLET should be used with caution in patients with heart problems or high or low blood pressure. Therefore, consult your doctor before taking it.

    Others

    Before taking MISOPROST 200MCG TABLET inform your doctor if you:

    • previously delivered a baby via caesarean section
    • have any problems in blood vessels
    • have inflammation in the bowel (such as ulcerative colitis, Crohn’s disease)
    • are more prone to dehydration easily

    Use in Paediatrics:

    MISOPROST 200MCG TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

    Use in Geriatrics:

    MISOPROST 200MCG TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.

    Interactions

    A. Drug-Drug interactions:

    Before taking MISOPROST 200MCG TABLET inform your doctor if you are taking any of the following medicines such as:

    • antacids (used to neutralize stomach acid) such as aluminium hydroxide, magnesium hydroxide
    • medicines used to manage heart problems (such as captopril, enalapril, lisinopril, amlodipine, nifedipine, diltiazem, verapamil, digoxin, methyldopa, amiodarone)

    Overdosage:

    If you or anyone else accidentally took more MISOPROST 200MCG TABLET, consult your doctor immediately or visit the nearby hospital.

    Synopsis

    Drug :   Misoprostol
    Pharmacological Category :   Prostaglandin Analogs
    Therapeutic Indication :   Peptic ulcer, Cervical Ripening, Abortifacient, Induction of labour pain
    Dosage Forms :   Tablet

    More Information

    • Keep MISOPROST 200MCG TABLET out of reach of children
    • Store MISOPROST 200MCG TABLET below 30°C

     

    FAQs About MISOPROST 200MCG TABLET

    Q: What is the use of MISOPROST 200MCG TABLET?

    A: MISOPROST 200MCG TABLET is used to manage peptic ulcer, predominantly caused due to excessive NSAID use (such as diclofenac, naproxen). It can also be used for cervical ripening (dilation) prior to certain uterine procedures and for inducing labour pain. It is also used in combination with mifepristone (an abortion pill) to induce abortion during the early stages of pregnancy (first trimester) and can manage excessive blood loss after childbirth.

    Q: How MISOPROST 200MCG TABLET works?

    A: MISOPROST 200MCG TABLET heals peptic ulcers by reducing excessive stomach acid secretion caused due to prolonged NSAIDs use. It also stimulates the contraction of uterine muscles which helps in initiating labour pain, reducing postpartum bleeding and for inducing abortion during the early stages of pregnancy. It also degrades the cells and tissues around the cervix, which helps in cervical ripening (softening) prior to uterine procedures.

    Q: How should I take MISOPROST 200MCG TABLET?

    A: Take MISOPROST 200MCG TABLET with meals to avoid stomach upset. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

    Q: What are the common side effects of taking MISOPROST 200MCG TABLET?

    A: The most common side effects of taking MISOPROST 200MCG TABLET are skin rashes, diarrhea, headache, dizziness, stomach pain, constipation, bloating, indigestion, birth defects (if accidentally exposed during pregnancy), vaginal bleeding (even after menopause) and severe uterine cramps. Consult your doctor if any of these side effects trouble you.

    Q: What precautions need to be followed while taking MISOPROST 200MCG TABLET?

    A: Take MISOPROST 200MCG TABLET with meals to avoid stomach upset. Avoid taking antacids (containing magnesium) along with this medicine as it may increase the risk of severe stomach problems. Before taking MISOPROST 200MCG TABLET inform your doctor if you previously delivered your baby via caesarean section. You must also inform your doctor if you have any heart problems, high or low blood pressure, inflammatory bowel diseases or problems in blood vessels as a precaution. Pregnant women should not get themselves exposed to this medicine as it may cause abortion or serious birth defects in the growing baby. 

    Q: Can MISOPROST 200MCG TABLET be used in children?

    A: MISOPROST 200MCG TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

    Q: Can MISOPROST 200MCG TABLET be used in post-menopausal women?

    A: MISOPROST 200MCG TABLET can be used in post-menopausal women. However, consult your doctor for advice before taking it.

    Q: Can the use of MISOPROST 200MCG TABLET cause unexpected bleeding?

    A: Yes. Irregular vaginal bleeding or spotting may occur while you are taking MISOPROST 200MCG TABLET. Consult your doctor if you experience prolonged painful bleeding.

    Q: What to do if I forgot to take MISOPROST 200MCG TABLET?

    A: If you forgot to take a dose of MISOPROST 200MCG TABLET, take it as soon as you remember. However, if it is time for the next dose of MISOPROST 200MCG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of MISOPROST 200MCG TABLET to compensate the missed ones.

    Q: Will the use of MISOPROST 200MCG TABLET change the length of menstrual cycle?

    A: Yes. MISOPROST 200MCG TABLET may delay your regular menstrual periods. Also, there are chances for sudden spotting or vaginal bleeding while taking MISOPROST 200MCG TABLET. But there is no reported evidence for long menstrual cycles.

    References

    1. KD. Tripathi. Prostaglandins, Leukotrienes and Platelet activation factor. Estrogens, Progestins and Contraceptives. Oxytocin and other drugs acting on the uterus. Drugs for Peptic ulcer and GERD. Essentials of medical pharmacology. Seventh edition. 2013. Page – 190, 319, 332 & 654.

    2. Marissa Krugh; Christopher V. Maani. Misoprostol. StatPearls. NIH National Library of Medicine. National Center for biotechnology information. PMC. PubMed Central. July 2022. [Accessed on 30th January 2023] https://www.ncbi.nlm.nih.gov/books/NBK539873/

    3. Pfizer Limited. Cytotec 200 microgram Tablets Misoprostol. Electronics Medicines Compendium. [Revised in October 2020]. [Accessed on 30th January 2023] https://www.medicines.org.uk/emc/files/pil.1642.pdf

    4. Zydus Pharmaceuticals USA Inc. Misoprostol Tablets. Dailymed.com. [Revised in January 2023]. [Accessed on 30th January 2023] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d5a40157-ec43-4918-b2d8-d7a4c17e3acd

    5. Cipla Ltd. Misoprost 25/200/600 Tablets (Misoprostol). Ciplamed.com. [Revised in January 2016]. [Accessed on 30th January 2023] https://ciplamed-library.com/content/misoprost-25-200-600-tablets

    6. Central Drugs Standard Control Organization. Misoprostol tablet 25mcg/100mcg/200mcg (additional strength indication). December 2006. Misoprostol 50Mcg tablet (Additional Strength). August 2008. Misoprostol. June 2001. Misoprostol Tablet 600mcg. January 2009. [Accessed on 30th January 2023] https://cdscoonline.gov.in/CDSCO/Drugs

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS
    Last updated on 31 Jan 2023 | 04:18 PM(IST)
    Lab updated