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Introduction About MIMCINA 30 TABLET
MIMCINA 30 TABLET contains Cinacalcet which belongs to a group of medicines called Calcimimetic agent that increases the sensitivity of the calcium-sensing receptor to activation by extracellular calcium. It is used for secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis and for hypercalcemia in patients with parathyroid outgrowth.
Hyperparathyroidism (HPT) is a condition where the parathyroid gland may become overactive and make too much PTH. In this condition the calcium stored in the bones move into the blood leading to hypercalcemia (too much calcium in the blood). Secondary hyperparathyroidism (SHPT) describes an alteration in bone and mineral metabolism that occurs as a direct result of chronic kidney disease (CKD). The parathyroid gland is the central organ responsible for regulating these adaptive responses leading to secondary hyperparathyroidism. Parathyroid hormone helps in low calcium levels by acting on the bones, intestine, and kidneys. MIMCINA 30 TABLET works by controlling levels of the parathyroid hormone (PTH), calcium and phosphorous in body.
Do not drive or operate machines, if you experience side effects such as dizziness and seizures while taking this medicine. If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby, ask your doctor for advice before taking this medicine. The most common side effects are nausea, vomiting, dizziness, rash, muscle pain, loss of appetite, headache. Consult your doctor if you experience any of the above side effects persists for a longer duration.
Uses Of MIMCINA 30 TABLET
It is used for:
- secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis
- hypercalcemia in patients with parathyroid outgrowth
How MIMCINA 30 TABLET Works
MIMCINA 30 TABLET works by controlling levels of the parathyroid hormone (PTH), calcium and phosphorous in body.
How to use MIMCINA 30 TABLET
Always take this medicine as advised by the physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking MIMCINA 30 TABLET unless your doctor advice you to stop.
Side Effects Of MIMCINA 30 TABLET
Common
- dizziness
- headache
- nausea or vomiting
- constipation
- feeling weak
- loss (anorexia) or decrease of appetite
- muscle pain
- weakness
- rash
- high potassium levels in the blood (hyperkalaemia)
- allergic reactions
- diarrhea
- indigestion
Stop taking MIMCINA 30 TABLET and contact your doctor immediately if you experience any of the following side effects:
- numbness or tingling around mouth, muscle aches or cramps and seizures. these may be signs of low calcium levels (hypocalcaemia)
- swelling of face, lips, mouth, tongue or throat which may cause by difficulty in swallowing or breathing (angioedema)
How To Manage Side Effects

Constipation
Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Headache
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Nausea And Vomiting
Keep taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Warning & Precautions

Pregnancy
Consult your doctorMIMCINA 30 TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor before taking it.

Breastfeeding
Consult your doctorIt is not known whether MIMCINA 30 TABLET is excreted in human milk. Therefore, consult your doctor before taking the medicine.

Driving and Using Machines
ContraindicatedDo not drive or operate any machinery while taking this medicine, it may make you feel dizziness.

Alcohol
ContraindicatedConsumption of alcohol is not recommended while taking MIMCINA 30 TABLET.

Kidney
Use with CautionMIMCINA 30 TABLET should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

Liver
Use with CautionMIMCINA 30 TABLET should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

Allergy
ContraindicatedDo not take MIMCINA 30 TABLET if you are allergic to any of its ingredients of this medicine.

Heart Disease
Use with CautionMIMCINA 30 TABLET should be taken with caution in patients with cardiac problems. Consult your doctor for advice.

Use In Pediatrics
Consult your doctorThe safety and efficacy of MIMCINA 30 TABLET in pediatric patients have not been established.

Use In Geriatrics
Use with CautionMIMCINA 30 TABLET should be used with caution in elderly patients above 65 years of age. Consult your doctor for advice.
Others
It is not recommended MIMCINA 30 TABLET if you have low levels of calcium in your blood
Interactions
A. Drug - Drug Interactions:
Before taking MIMCINA 30 TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used for skin and fungal infections
- medicines used for bacterial infections (telithromycin, rifampicin and ciprofloxacin)
- medicines used for viral infection (ritonavir)
- medicines used to manage depression (fluvoxamine)
- medicines used to relieve cough (dextromethorphan)
- medicines used for changes in heart rate (flecainide and propafenone)
- medicines used to manage high blood pressure
B. Drug - Food Interaction:
- It is advised to take MIMCINA 30 TABLET with food or shortly after a meal.
Overdosage:
- If you or anyone else accidentally took more MIMCINA 30 TABLET, consult your doctor immediately or visit your nearby hospital. Symptoms of overdosage is hypocalcemia.
Synopsis
Drug |
: |
Cinacalcet |
Pharmacological Category | : | Calcimimetics |
Therapeutic Indication | : | Hyperparathyroidism |
Dosage Forms | : | Tablet |
More Information
- Keep MIMCINA 30 TABLET out of reach of children
- Store MIMCINA 30 TABLET at room temperature
FAQs About MIMCINA 30 TABLET
Q: Can MIMCINA 30 TABLET be used in pregnant women?
A: No. It is not recommended for use in the pregnant women. Consult your doctor before taking.
Q: How and when to take MIMCINA 30 TABLET?
A: Take MIMCINA 30 TABLET preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: How long should I take MIMCINA 30 TABLET?
A: You need to take MIMCINA 30 TABLET as long as your doctor or physician prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
Q: What is the best time to take MIMCINA 30 TABLET?
A: MIMCINA 30 TABLET must be taken after meals to avoid gastrointestinal side effects. Consult your doctor for advice.
Q: What to do if I forgot to take a dose of MIMCINA 30 TABLET?
A: If you forgot to take a dose of MIMCINA 30 TABLET, take it as soon as you remember. However, if it is time for the next dose of MIMCINA 30 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of MIMCINA 30 TABLET to compensate the missed ones.
Q: What are the most common side effects of taking MIMCINA 30 TABLET?
A: The most common side effects of MIMCINA 30 TABLET are nausea, vomiting, dizziness, rash, muscle pain, loss of appetite, headache. Consult your doctor if you experience any of the above side effects persists for a longer duration.
Q: Can I stop taking MIMCINA 30 TABLET without consulting your doctor?
A: No. You should not stop taking MIMCINA 30 TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using MIMCINA 30 TABLET, consult your doctor for advice.
References
1. K.D. Tripathi, Essentials of medical pharmacology, Cardiovascular drugs, Chapter 39 - Anti anginal and other ischaemic drugs, Page – 554.
2. Lionel H. Opie, Bernard J. Gersh, Drugs for the heart, Drugs Used in anti anginals, Eighth Edition, 2013. Page – 55-56.
3. Bharath M. Reddy, MD, Howard S. Weintraub, MD, and Arthur Z. Schwartzbard, MD, A New Approach to Treating an Old Problem. [Accessed on January 09th, 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014127/pdf/20101200s00004p641.pdf
4. Amgen Europe B.V; Electronic Medicines Compendium (EMC); [Revised on August, 2017] [Accessed on January 09th, 2024] https://www.medicines.org.uk/emc/files/pil.5599.pdf
5. Amgen Inc.; U.S. Food & Drug Administration; [Revised on August, 2011] [Accessed on January 09th, 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021688s017lbl.pdf
Useful Diagnostic Tests
- Thyroid Stimulating Hormone (TSH)
- Urine Routine & Microscopy
- Kidney Function Test (KFT)
- Thyroid Profile -Total (T3,T4&Tsh)
- Thyroid Profile- Free (Ft3, Ft4 & Tsh)
- Creatinine, Serum
- Uric Acid, Serum
- Albumin, Serum