Mignar 50mg Tablet 15'S

Introduction About MIGNAR 50MG TABLET

MIGNAR 50MG TABLET contains Miglitol that belongs to the group of medicines called Oral Alpha-Glucosidase Inhibitors. It is used in adults to improve glycaemic control with type 2 diabetes mellitus as an adjunct to diet and exercise.

Type 2 diabetes mellitus is a long-standing metabolic disorder in which there is impairment of body cells to uptake and utilize glucose, resulting in excessive glucose in blood. It is characterized by the symptoms such as increased thirst, increased frequency of urination, increased hunger, weakness, weight loss, and blurred vision.  

Miglitol works by reversibly inhibiting of membrane-bound enzymes that play a vital role in the breakdown of sugar (oligosaccharides and disaccharides) into glucose (monosaccharides), thereby delaying glucose absorption and lowering the blood glucose levels.

MIGNAR 50MG TABLET is not recommended for use if you have diabetic ketoacidosis, inflammatory bowel disease (including colonic ulceration, partial intestinal obstruction), chronic intestinal diseases associated with digestive or absorptive disorders, predisposition to intestinal obstruction, or chronic intestinal diseases that may deteriorate due increased gas formation in the intestine. MIGNAR 50MG TABLET is also not recommended for use in pregnant women, breastfeeding women, and children. It should be used with caution in elderly patients (aged above 65 years).Consult your doctor before taking.

The most common side effects associated with the use of MIGNAR 50MG TABLET are flatulence, soft stools, diarrhoea, abdominal discomfort, and skin rashes. Consult your doctor if any of the symptom worsens.

Uses Of MIGNAR 50MG TABLET

• It is used in adults to improve glycaemic control with type 2 diabetes mellitus as an adjunct to diet and exercise.

How MIGNAR 50MG TABLET Works

MIGNAR 50MG TABLET helps in improving glycaemic control where miglitol works by reversibly inhibiting of membrane-bound enzymes that play a vital role in the breakdown of sugar (oligosaccharides and disaccharides) into glucose (monosaccharides), thereby delaying glucose absorption and lowering the blood glucose levels.

How to use MIGNAR 50MG TABLET

Take MIGNAR 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water with food or between meals. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of MIGNAR 50MG TABLET

How To Manage Side Effects

Diarrhea

Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhoea and consult your doctor if the symptom gets worse.

Warning & Precautions

Pregnancy

Contraindicated

MIGNAR 50MG TABLET is not recommended for use in pregnant women unless considered necessary. Consult your doctor before taking.

Breastfeeding

Contraindicated

MIGNAR 50MG TABLET is not recommended for use in breastfeeding women as it can pass through milk. Consult your doctor taking.

Kidney

Safe

No dose adjustment for MIGNAR 50MG TABLET is needed in patients with renal impairment. Consult your doctor before taking.

Liver

Safe

No dose adjustment for MIGNAR 50MG TABLET is needed in patients with hepatic impairment. Consult your doctor before taking.

Allergy

Contraindicated

Do not take MIGNAR 50MG TABLET if you are allergic to miglitol, or any other ingredients of this medicine. Consult your doctor before taking.

Use In Pediatrics

Contraindicated

MIGNAR 50MG TABLET is not recommended for use in children. Consult your doctor before taking.

Use In Geriatrics

Use with Caution

MIGNAR 50MG TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking.

Interactions

A. Drug-Drug Interactions:

Before taking MIGNAR 50MG TABLET, inform your doctor, if you are taking any of the following medicine:

• glyburide, Metformin (medicine used to manage diabetes)
• digoxin (medicine used to manage cardiovascular disorders)
• ranitidine, propranolol (medicine used to manage acidity)
• intestinal adsorbents (medicines used to manage diarrhoea) Ex. charcoal
• digestive enzyme preparations Ex. amylase, pancreatin

Overdosage:

If you or anyone else accidentally takes too much of MIGNAR 50MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are temporary increase in diarrhoea, flatulence, and abdominal discomfort.

Synopsis

More Information

• Keep MIGNAR 50MG TABLET out of reach in children
• Store at 25°C

FAQs About MIGNAR 50MG TABLET

Q: What MIGNAR 50MG TABLET is used for?

A: MIGNAR 50MG TABLET is used in adults to improve glycaemic control with type 2 diabetes mellitus as an adjunct to diet and exercise. Consult your doctor before taking it.

Q: What happens if you take more MIGNAR 50MG TABLET than your required dose?

A: If you or anyone else accidentally takes too much of MIGNAR 50MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are temporary increase in diarrhoea, flatulence, and abdominal discomfort.

Q: What side effects are seen with MIGNAR 50MG TABLET?

A: The most common side effects associated with the use of MIGNAR 50MG TABLET are flatulence, soft stools, diarrhoea, abdominal discomfort, and skin rashes. Consult your doctor if any of the symptom worsens.

Q: Who should avoid taking MIGNAR 50MG TABLET?

A: MIGNAR 50MG TABLET is not recommended for use if you have diabetic ketoacidosis, inflammatory bowel disease (including colonic ulceration, partial intestinal obstruction), chronic intestinal diseases associated with digestive or absorptive disorders, predisposition to intestinal obstruction or chronic intestinal diseases that may deteriorate due increased gas formation in the intestine. MIGNAR 50MG TABLET is also not recommended for use in pregnant women, breastfeeding women, and children. Consult your doctor before taking.

Q: How MIGNAR 50MG TABLET works?

A: MIGNAR 50MG TABLET helps in improving glycaemic control where miglitol works by reversibly inhibiting of membrane-bound enzymes that play a vital role in the breakdown of sugar (oligosaccharides and disaccharides) into glucose (monosaccharides), thereby delaying glucose absorption and lowering the blood glucose levels.

Q: What is method of taking MIGNAR 50MG TABLET?

A: Take MIGNAR 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water with food or between meals. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Q: Is MIGNAR 50MG TABLET safe to be used in pregnant women?

A: MIGNAR 50MG TABLET is not recommended for use in pregnant women unless considered necessary as safety of this medicine in this population is not established. Consult your doctor before taking.

Q: Is MIGNAR 50MG TABLET safe to be used in breastfeeding women?

A: MIGNAR 50MG TABLET is not recommended for use in breastfeeding women as it can pass through milk. However, the amount of this medicine reached in human milk is very low. Consult your doctor taking.

Q: Is MIGNAR 50MG TABLET safe to be used in children?

A: MIGNAR 50MG TABLET is not recommended for use in children because the safety and effectiveness of this medicine in children has not been established. Consult your doctor before taking.

References

1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page - 277.

2. Satoru Sugimoto, Hisakazu Nakajima, Kitaro Kosaka, Hajime Hosoi. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. December 2015. [Assessed on 07th December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666030/

3. Bayer HealthCare Pharmaceuticals Inc. Food and Drug Administration (FDA). [Revised in August 2012] [Assessed on 07th December 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020682s010lbl.pdf

4. Bayer HealthCare Pharmaceuticals Inc. Glyset®. [Revised in August 2016] [Assessed on 07th December 2022] https://labeling.pfizer.com/ShowLabeling.aspx?id=581

Useful Diagnostic Tests

• Blood sugar test

Author Details

Written By Dr. R. Dinesh John Rajkumar - Pharm.D

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 18 Oct 2023 | 05:06 PM(IST)