Mifty Kit Tablet

Introduction About MIFTY KIT TABLET

MIFTY KIT TABLET is a combination of Mifepristone and Misoprostol that belongs to the group of medicines Anti-progestational steroids and Synthetic prostaglandin. It is used for the medical termination of the pregnancy no later than 63 days after the first day of your last menstrual period.

Before taking MIFTY KIT TABLET, inform your doctor if you have kidney, liver, respiratory problems, high blood pressure, high blood cholesterol levels, suffer from an illness that may affect the clotting of your blood, anaemia or malnourished.

MIFTY KIT TABLET is contraindicated if your pregnancy has not been confirmed, if the first day of your last period was more than 63 days ago, or if your doctor suspects an ectopic pregnancy, have hereditary porphyria, suffer from chronic adrenal failure.

Failure of pregnancy termination (continuing pregnancy) after taking MIFTY KIT TABLET after the first medicine (mifepristone) leads to increased risk of birth defects like facial paralysis, head, and limb malformations. Consult your doctor before taking it.

MIFTY KIT TABLET may pass into breast milk, hence stop breastfeeding once you have used the management. Consult your doctor before taking it. MIFTY KIT TABLET should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Avoid grapefruit juice when you are managed with MIFTY KIT TABLET.

The common side effects of MIFTY KIT TABLET are uterine contractions, lower abdominal cramps, heavy bleeding, gastrointestinal cramping, nausea, vomiting or diarrhoea. If any of these side effect get worsen, contact your doctor for advice.

Uses Of MIFTY KIT TABLET

• It is used for medical termination of pregnancy no later than 63 days after the first day of your last menstrual period

How MIFTY KIT TABLET Works

MIFTY KIT TABLET contains Mifepristone blocks the action of the progesterone hormone required in women to continue the pregnancy. Misoprostol increases the uterus contraction and dilates the cervix, that results in expelling the pregnancy. Thus, the combination of Mifepristone and Misoprostol causes termination of pregnancy.

How to use MIFTY KIT TABLET

Take MIFTY KIT TABLET as advised by your physician. Check the label before use. Your doctor will decide the right dose depends on your age, body weight and disease condition.

Side Effects Of MIFTY KIT TABLET

How To Manage Side Effects

Warning & Precautions

Interactions

A. Drug - Drug interactions:

Before taking MIFTY KIT TABLET, inform your doctor if you are taking any of the following medicine:

• medicines used to manage asthma or inflammation (Ex. dexamethasone)
• medicines used to manage fungal infection (Ex. ketoconazole, itraconazole)
• antibiotics (Ex. erythromycin)
• St. John’s Wort (natural remedy used to manage mild depression)
• medicines used to manage seizures or epilepsy (Ex. phenytoin, phenobarbital)
• medicines used to manage the body from rejecting a transplanted organ (Ex. cyclosporine, tacrolimus, sirolimus)
• painkiller medicines (Ex. alfentanil, fentanyl)
• medicines used to manage migraine (Ex. ergotamine, diergotamine)
• medicines used to help keep the heart beating normally (Ex. quinidine)
• some medicines used during general anaesthesia

B. Drug - Food interaction:

Avoid grapefruit juice when you are managed with MIFTY KIT TABLET. Consult your doctor before taking the medicine.

Overdosage:

If you or anyone else takes too much of MIFTY KIT TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Mifepristone, Misoprostol
Pharmacological Category	:	Antiprogesterone steroids, Prostaglandins analogues
Therapeutic Indication	:	Medical termination of pregnancy
Dosage Forms	:	Tablet, Kit

More Information

• Keep MIFTY KIT TABLET out of reach of children
• Store at room temperature

FAQs About MIFTY KIT TABLET

Q: What is Mifty Kit Tablet used for?

A: Mifty Kit Tablet is recommended for medical termination of pregnancy which should be used only under careful medical supervision.

Q: When should I start using Mifty Kit Tablet for safe medical termination?

A: Your doctor may recommend you take Mifty Kit Tablet within 63 days from your last menstrual period. Please note that Mifty Kit Tablet should be used strictly under medical supervision.

Q: When will I start bleeding after taking Mifty Kit Tablet?

A: You may experience bleeding within 1-4 hours of using Mifty Kit. This time period may vary from person to person based on health condition. You may notice large blood clots along with tissues during this time. However, if you didn’t experience bleeding or have only slight spotting, check with your doctor.

Q: When will I get my period after taking Mifty Kit?

A: Usually, you may get your first periods after medical termination of pregnancy in about 4-8 weeks. If face any difficulty, check with your doctor.

Q: I have used Mifty Kit Tablet but sustained with pregnancy. What should I do?

A: Limited information is available regarding the risks posed to the unborn child. In cases where pregnancy termination (continuation of pregnancy) occurs after the administration of fMifty Kit Tablet ollowing the initial dose of mifepristone, there appears to be a threefold heightened risk of birth defects, notably facial paralysis, as well as malformations in the head and limbs. If the decision is made to proceed with the pregnancy, thorough prenatal monitoring and ultrasound evaluations, with a specific focus on the limbs and head, should be conducted at a specialized clinic.

Q: Can I breastfeed while taking Mifty Kit Tablet?

A: No. Do not breastfeed while taking Mifty Kit, as it may pass through the breast milk and affect the nursing infant. You should stop breastfeeding once you have used the management and consult your doctor before restarting.

Q: How should I take Mifty Kit?

A: Mifty Kit should be taken only under medical supervision in a hospital setting. Therefore, consult your doctor. Do not self-adminster.

Q: Will the use of Mifty Kit Tablet affect the chance of future pregnancy?

A: It is possible for you to conceive shortly after the completion of pregnancy termination. It's advisable to refrain from attempting to conceive again until after your next menstrual cycle following the administration of Mifty Kit. Additionally, it's recommended to employ a contraceptive method within 3 to 9 days of taking the mifepristone tablet.

Q: What exactly can I expect after taking Mifty Kit Tablet?

A: After taking Mifty Kit, you may bleed slightly heavier, and the bleeding/spotting can continue for few weeks. Over time, bleeding and cramps should stop on its own. If you experience severe unmanageable bleeding, consult your doctor immediately.

Q: During which month of pregnancy, the use of Mifty Kit is considered safe?

A: Mifty Kit is usually taken within first 63 days of last menstrual period.

Q: Is Mifty Kit safe?

A: The use of Mifty Kit Tablet is highly risky. Therefore, careful medical supervision is required.

Q: What caution is required after management with MIFTY KIT TABLET?

A: After management you should be aware that uterine bleeding usually starts 1 to 2 days after taking the medicine. The bleeding lasts 2 or 3 weeks, if the bleeding is heavy and prolonged, contact the doctor immediately. 

Q: Do you feel pain during the management with MIFTY KIT TABLET?

A: During the management with MIFTY KIT TABLET there could be symptoms like uterine contractions, lower abdominal cramps, heavy bleeding, and discomfort. Consult your doctor if you feel unwell.

Q: What if I miss the dose of MIFTY KIT TABLET?

A: If you forget to use any part of the management, its effectiveness may be compromised, potentially resulting in incomplete expulsion of the pregnancy. It is important to seek advice from your doctor promptly, as you might require additional management to terminate the pregnancy fully.

Q: How many days bleeding is normal after management with MIFTY KIT TABLET?

A: The bleeding usually continues a few days to two weeks and should become light after the first few days. You may also pass some blood clots or tissue or have light bleeding for longer than two weeks. Consult your doctor if there is a bleeding for a longer period.

Q: What are the side effects of MIFTY KIT TABLET?

A: The common side effects of MIFTY KIT TABLET are uterine contractions, lower abdominal cramps, heavy bleeding, gastrointestinal cramping, nausea, vomiting or diarrhoea. If any of these side effect gets worsen, contact your doctor for advice.

References

1. KD. Tripathi. Prostaglandins, Leukotrienes (Eicosanoids) and Platelet Activating Factor. Essentials of medical pharmacology. Seventh edition. 2017. Page – 181.

2. Raymond EG, Shannon C, Weaver MA, Winikoff B. First-trimester medical abortion with mifepristone 200 mg and misoprostol: a systematic review. Contraception. PubMed, January 2013. [Accessed on 31st January 2023] https://pubmed.ncbi.nlm.nih.gov/22898359/

3. Medical Abortion with Mifepristone + Misoprostol (13 - 22 Weeks) National Library of Medicine. [Revised in May 2014] [Accessed on 31st January 2023] https://clinicaltrials.gov/ct2/show/NCT01768299

4. Macleods Pharma. Mifepristone, Misoprostol. [Accessed on 31st January 2023] https://www.macleodspharma.com/products/

5. Sun Pharmaceutical Industries Europe. Mifepristone, Misoprostol. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 31st January 2023] https://www.medicines.org.uk/emc/files/pil.3380.pdf

6. Danco Laboratories. Mifepristone, Misoprostol. [Revised in March 2016] [Accessed on 31st January 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020687s020lbl.pdf

7. Cipla Med. Mifepristone, Misoprostol. [Accessed on 31st January 2023] https://ciplamed-library.com/content/mtp-kit

Useful Diagnostic Tests

• Complete blood test
• Gynaecological diagnosis

Author Details