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Introduction About MIACALCIC 200IU NASAL SPRAY
MIACALCIC 200IU NASAL SPRAY contains Calcitonin which belongs to the group of medicines called Calcium metabolism modifiers. It is used to manage postmenopausal osteoporosis (weak or brittle bones caused during menopause) in women who have crossed 5 years of menopause when other managements are not appropriate.
Prior to the management, the doctor will perform a skin test to determine whether you are allergic to calcitonin or not. During management with MIACALCIC 200IU NASAL SPRAY, your doctor may take several bone-related tests to evaluate improvement in your condition. You may also be prescribed vitamin D or calcium supplements along with MIACALCIC 200IU NASAL SPRAY to improve your disease condition.
Before using MIACALCIC 200IU NASAL SPRAY, inform your doctor if you have low blood calcium levels or any type of cancer as a precaution. Do not use MIACALCIC 200IU NASAL SPRAY without consulting your doctor if you are pregnant or breastfeeding.
The most common side effects of using MIACALCIC 200IU NASAL SPRAY are nasal irritation, headache, back pain, and muscle pain. Consult your doctor if any of these side effects worsen.
Uses Of MIACALCIC 200IU NASAL SPRAY
It is used among women (greater than 5 years of menopause) to:
- Manage postmenopausal osteoporosis
How MIACALCIC 200IU NASAL SPRAY Works
MIACALCIC 200IU NASAL SPRAY stops the action of certain bone cells (such as osteoclasts) that destroy the bone mass. This action manages bone loss and helps build bone mass and density. As a result, it makes your bones stronger and reduces the risk of fracture.
How to use MIACALCIC 200IU NASAL SPRAY
Use MIACALCIC 200IU NASAL SPRAY as advised by your physician. It is for intranasal use only. Prior to use, prime the device by pressing 2-3 puffs in the air. Place the nozzle of the device inside your nostril and gently press the pump to release the spray.
As MIACALCIC 200IU NASAL SPRAY must be stored in the refrigerator, allow it to come to room temperature before use.
Your doctor will decide the suitable dose, number of sprays, and duration of therapy for you depending upon your age, body weight, and health condition. Do not stop using MIACALCIC 200IU NASAL SPRAY without consulting your doctor.
Side Effects Of MIACALCIC 200IU NASAL SPRAY
Common
- back pain, muscle pain
- headache
- runny nose
- nasal irritation or dryness
Rare
Stop using MIACALCIC 200IU NASAL SPRAY and contact your doctor immediately if you experience any of the following side effects, such as:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, eyes, tongue, or throat causing wheezing or difficulty breathing, chest tightness, a fall in blood pressure, or an increased heartbeat)
- signs of hypocalcemia (such as tingling or numbness of fingers, toes, or around the mouth)
- severe nasal irritation with nasal bleeding, redness, swelling or soreness, crusting sensation, and nasal dryness
How To Manage Side Effects
Headache
Rest and relax. Drink plenty of fluids, such as water or electrolytes, and apply a pain-relieving balm to the head if necessary. Do not consume alcohol. Contact your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
Consult your doctorThere are no adequate studies to confirm the effects of MIACALCIC 200IU NASAL SPRAY on pregnant women. Therefore, MIACALCIC 200IU NASAL SPRAY should be used in pregnant women only if considered necessary by the physician.
Breastfeeding
Consult your doctorThere are no adequate studies to confirm whether MIACALCIC 200IU NASAL SPRAY can pass through breast milk or not. Therefore, MIACALCIC 200IU NASAL SPRAY should be used in breastfeeding women only if considered necessary by the physician.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if your abilities are affected by MIACALCIC 200IU NASAL SPRAY.
Allergy
ContraindicatedTalk to your doctor before using MIACALCIC 200IU NASAL SPRAY if you are allergic to calcitonin.
Use In Pediatrics
ContraindicatedMIACALCIC 200IU NASAL SPRAY is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before using it.
Use In Geriatrics
Use with CautionMIACALCIC 200IU NASAL SPRAY should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before using it.
Others
Before using MIACALCIC 200IU NASAL SPRAY, inform your doctor if you have:
- hypocalcaemia (low calcium levels in the blood)
- any form of cancer
Interactions
A. Drug-Drug interactions:
Before using MIACALCIC 200IU NASAL SPRAY, inform your doctor if you are taking any of the following medicines, such as:
- medicines used to manage depression and mania (Ex. lithium)
- other medicines used to manage osteoporosis (Ex. alendronate, zoledronic acid)
Overdosage:
If you or anyone else accidentally took more MIACALCIC 200IU NASAL SPRAY, contact your doctor or go to the nearest hospital right away.
Synopsis
| Drug | : | Calcitonin |
| Pharmacological Category | : | Calcitonin Receptor Agonist |
| Therapeutic Indication | : | Postmenopausal Osteoporosis |
| Dosage Forms | : | Injection, Nasal Spray |
More Information
- Keep MIACALCIC 200IU NASAL SPRAY out of the sight and reach of children
- Store in a refrigerator between 2-8°C
FAQs About MIACALCIC 200IU NASAL SPRAY
Q: What is the use of MIACALCIC 200IU NASAL SPRAY?
A: MIACALCIC 200IU NASAL SPRAY is used to manage postmenopausal osteoporosis (weak or brittle bones caused during menopause) in women who have crossed 5 years of menopause when other managements are not appropriate.
Q: How do I use MIACALCIC 200IU NASAL SPRAY?
A: MIACALCIC 200IU NASAL SPRAY is for intranasal use only. Prior to use, prime the device by pressing 2-3 puffs in the air. Place the nozzle of the device inside your nostril and gently press the pump to release the spray.
Q: What are the side effects of MIACALCIC 200IU NASAL SPRAY?
A: The most common side effects of using MIACALCIC 200IU NASAL SPRAY are nasal irritation, headache, back pain, and muscle pain. Consult your doctor if any of these side effects worsen.
Q: Can elderly patients use MIACALCIC 200IU NASAL SPRAY?
A: Yes, elderly patients can use MIACALCIC 200IU NASAL SPRAY after consulting their doctor.
Q: Can MIACALCIC 200IU NASAL SPRAY manage osteoporosis?
A: Yes. MIACALCIC 200IU NASAL SPRAY helps in managing osteoporosis and helps in gaining back lost bone mass in postmenopausal women.
Q: How does MIACALCIC 200IU NASAL SPRAY work?
A: MIACALCIC 200IU NASAL SPRAY stops the action of certain bone cells (such as osteoclasts) that destroy the bone mass. This action manages bone loss and helps build bone mass and density. As a result, it makes your bones stronger and reduces the risk of fracture.
Q: Can I stop therapy with MIACALCIC 200IU NASAL SPRAY once my symptoms subside?
A: No. Do not stop using MIACALCIC 200IU NASAL SPRAY without consulting your doctor once your symptoms subside, as it may reverse the healed condition. Continue to use MIACALCIC 200IU NASAL SPRAY as long as instructed by your doctor.
Q: Can MIACALCIC 200IU NASAL SPRAY cause cancer?
A: Yes. MIACALCIC 200IU NASAL SPRAY might cause cancer when used in the long term. Therefore, contact your doctor for advice before using it.
References
1. KD. Tripathi. Drugs affecting Calcium Balance. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 340.
2. C H Chesnut 3rd 1, S Silverman, K Andriano, H Genant, A Gimona, S Harris, D Kiel, M LeBoff, M Maricic, P Miller, C Moniz, M Peacock, P Richardson, N Watts, D Baylink. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF Study Group. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. Pubmed.gov. September 2000. [Accessed on 1st February 2024] https://pubmed.ncbi.nlm.nih.gov/10996576/
3. Novartis Pharma Stein AG. U.S. Food & Drug Administration. [Revised in September 2017] [Accessed on 1st February 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020313s036lbl.pdf
4. Novartis Pharmaceutical Corporation. U.S. Food & Drug Administration. [Revised in July 2011] [Accessed on 1st February 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020313s033lbl.pdf
5. Par Pharmaceutical. Calcitonin. [Revised in June 2016] [Accessed on 1st February 2024] https://www.parsterileproducts.com/pdfs/catalog/generic/Calcitonin_PI_20200506.pdf
6. Calcitonin. Apotex Inc. [Revised in November 2017] [Accessed on 1st February 2024] https://www1.apotex.com/products/us/downloads/pil/calc_naso_pil.pdf
7. Apotex Corp. Dailymed. [Revised in January 2021] [Accessed on 1st February 2024] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c82eb602-12e1-692b-d660-f8d5b5736b54&audience=professional
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