Metosartan 50mg Tablet 10'S

Introduction About METOSARTAN 50MG TABLET

Metosartan 50mg Tablet is a combination medicine used to manage high blood pressure (hypertension). It may also be used to lower the risk of heart attack, heart failure and stroke in future. It contains Metoprolol and Telmisartan, which work together to control blood pressure and reduce the risk of heart-related complications.

It is recommended to take Metosartan 50mg Tablet with food at the same time each day to maintain consistent blood levels. Continue taking it as prescribed by your doctor, even if you feel fine, since high blood pressure often presents no symptoms. Stopping the medication abruptly can worsen your condition. Along with the medicine, staying active, maintaining a healthy diet, and managing your weight can further help control blood pressure. Always follow your doctor’s guidance while on this therapy.

Common side effects include headache, weakness, dizziness, low blood pressure, increased potassium levels, orthostatic hypotension (which may lead to fainting), breathlessness, nausea, vomiting, abdominal pain, and fatigue. It is advised to avoid potassium-rich foods or supplements while taking this medicine. Since it can cause dizziness, avoid driving or get up slowly from a seated position. Regular monitoring of blood pressure, blood sugar, kidney function, urea, and electrolyte levels may be required during treatment.

Before starting this medicine, inform your doctor if you have any kidney or liver issues. Pregnant or breastfeeding women should consult their doctor before use. Also, let your doctor know about any other medications you are taking, particularly those for blood pressure or heart conditions.

Uses Of METOSARTAN 50MG TABLET

• Effectively controls high blood pressure (hypertension)
• Reduces the risk of heart attack and stroke
• Improves overall heart health

Benefits of METOSARTAN 50MG TABLET

Metosartan 50mg for High Blood Pressure:

• Metosartan 50mg Tablet is a widely prescribed antihypertensive medication that helps control high blood pressure (hypertension) effectively.
• This combination medicine is beneficial in reducing the risk of heart attack, stroke, and kidney damage caused by uncontrolled hypertension.
• Taking Metosartan 50mg regularly helps maintain stable blood pressure levels, preventing complications associated with long-term hypertension.
• Always consult your doctor for the correct Metosartan 50mg dosage and precautions before use.

Metosartan 50mg for Heart Health:

• Metosartan 50mg is highly effective in protecting heart health by reducing the workload on the heart and ensuring smooth blood circulation.
• It helps in managing angina (chest pain), preventing heart failure, and lowering the risk of cardiovascular diseases.
• By blocking stress hormones and dilating blood vessels, this medication ensures a steady heart rate, controlled blood pressure, and reduced strain on the heart.
• Regular use of Metosartan 50mg, under medical supervision, can improve heart function and prevent heart-related complications in hypertensive patients.

Metosartan 50mg: Long-Term Benefits for High BP Patients

• Long-term use of Metosartan 50mg provides consistent blood pressure control, reducing the risk of severe health issues like stroke, heart attack, kidney disease, and arterial damage.
• Its dual-action formula ensures both steady heart function and vascular relaxation, making it a preferred choice for chronic hypertension management.
• Patients on Metosartan 50mg often experience better heart efficiency, improved exercise tolerance, and reduced BP fluctuations.
• However, regular BP monitoring, dietary adjustments, and adherence to the prescribed dosage are essential for maximizing its long-term benefits in high blood pressure patients.

How METOSARTAN 50MG TABLET Works

How Metosartan 50mg Works for Hypertension:

Metosartan 50mg is a combination antihypertensive medication containing Metoprolol (a beta-blocker) and Telmisartan (an angiotensin receptor blocker - ARB). These two active ingredients work together to effectively lower high blood pressure and protect the heart from complications.

• Metoprolol blocks beta receptors in the heart, reducing heart rate and the force of contraction, which lowers blood pressure and decreases the heart’s workload.
• Telmisartan blocks the angiotensin II hormone, preventing blood vessel constriction, leading to wider blood vessels and improved blood flow, reducing BP levels.

This dual mechanism effectively controls hypertension, improves blood circulation, and reduces the risk of heart attacks, strokes, and kidney damage in hypertensive patients.

How Metosartan 50mg Works for Controlling Heart Attack:

Metosartan 50mg helps reduce the risk of heart attack by lowering blood pressure, improving blood flow, and reducing strain on the heart. It contains two key ingredients:

• Metoprolol (Beta-Blocker): Slows down the heart rate and reduces the force of heart contractions, which lowers oxygen demand and prevents excessive stress on the heart, reducing the risk of heart attacks.
• Telmisartan (Angiotensin Receptor Blocker - ARB): Helps relax and widen blood vessels, improving blood circulation and preventing sudden spikes in blood pressure, which can trigger heart attacks.

By controlling hypertension, improving heart efficiency, and reducing cardiovascular stress, Metosartan 50mg plays a crucial role in preventing heart attacks and other heart-related complications in high-risk patients. Regular use under medical supervision ensures optimal heart protection and long-term cardiovascular health.

How to use METOSARTAN 50MG TABLET

How to Take Metosartan 50mg Tablet?

• Metosartan 50mg should be taken exactly as prescribed by your doctor to ensure effective blood pressure control and heart health benefits.
• Swallow the tablet whole with a glass of water, without crushing or chewing it.
• It can be taken with or without food, but consistency in timing helps maintain steady blood levels.

Metosartan 50mg: Morning or Night?

Metosartan 50mg can be taken either in the morning or at night, depending on your doctor’s recommendation. However, if it causes dizziness or drowsiness, taking it at night may be beneficial.

Metosartan 50mg: Once or Twice Daily?

The dosage frequency depends on your doctor’s prescription and your blood pressure levels. While many patients take Metosartan 50mg once daily, some may need twice-daily dosing for better BP control.

Metosartan 50mg Tablet Dosage Instructions:

• Standard Dosage for Hypertension: Usually one tablet per day or as directed by the doctor.
• Dosage Adjustment in Elderly Patients: Lower doses may be required due to age-related changes in kidney and liver function.

Adjusting Metosartan 50mg Dose for Better BP Control:

If blood pressure is not adequately controlled, your doctor may adjust the dose or combine it with other antihypertensive medications for better results. Never adjust the dose on your own.

How Many Times Should I Take Metosartan 50mg Daily?

Most patients take Metosartan 50mg once daily, but in severe hypertension cases, doctors may prescribe twice-daily dosing for better control.

What if I forgot to take METOSARTAN 50MG TABLET

• Take the missed dose as soon as you remember.
• If it's close to the next dose, skip the missed dose and continue as scheduled.
• Do not double the dose to make up for a missed one.

Overdose

Taking too much Metosartan 50mg can cause severe low blood pressure, dizziness, fainting, or slow heart rate. If you suspect an overdose, seek immediate medical attention.

Side Effects Of METOSARTAN 50MG TABLET

Like all medicines, Metosartan 50mg Tablet may cause certain side effects although not everybody gets them.

Common Side Effects of Metosartan 50mg:

• Dizziness or fatigue
• Low blood pressure
• Slow heart rate
• Nausea
• Diarrhoea
• Itchy skin and rashes
• vertigo (sudden internal or external spinning sensation)

Metosartan 50mg Long-Term Side Effects:

Long-term use of Metosartan 50mg is generally safe when taken under medical supervision. However, prolonged use may cause:

• Electrolyte imbalances (low sodium or potassium levels)
• Kidney function changes (if not monitored properly)
• Heart rate irregularities in some individuals
• Increased risk of low blood pressure (hypotension)
• Fatigue or decreased exercise tolerance

Regular blood pressure, kidney function, and electrolyte level monitoring can help prevent these complications.

Metosartan 50mg Side Effects on Kidneys:

Metosartan 50mg can affect kidney function, especially in patients with pre-existing kidney disease. Possible effects include:

• Changes in creatinine levels (indicating kidney stress)
• Reduced kidney filtration rate (leading to fluid retention)
• Electrolyte disturbances (such as high potassium levels)

Patients with kidney disease should have regular kidney function tests while on Metosartan.

Metosartan 50mg Side Effects on Heart:

Although Metosartan protects the heart, in some cases, it may cause:

• Bradycardia (slow heart rate)
• Excessive drop in blood pressure leading to fainting
• Heart palpitations or irregular heartbeats
• In rare cases, worsening of pre-existing heart failure

Metosartan 50mg Serious Side Effects:

Seek immediate medical attention if you experience:

• Severe dizziness or fainting
• Extreme weakness or confusion
• Swelling of the face, lips, or throat (allergic reaction)
• Shortness of breath or chest pain
• High potassium levels (causing muscle weakness or irregular heartbeats)

How To Manage Side Effects

Diarrhea

• Drink Fluids: Drink clear fluids such as water, broths, and oral rehydration solutions (ORS).
• Electrolytes: If you are losing a lot of fluids (for example, from frequent diarrhea), consider drinking an electrolyte solution to help replenish lost minerals like potassium and sodium.
• BRAT Diet: Try to take Bananas, Rice (white rice), Apple sauce and Toast (plain, without butter) to control diarrhoea management.
• Avoid Certain Foods: While recovering avoid the following food items such as fatty, greasy, or fried foods, spicy foods, dairy products (especially if you have a temporary lactose intolerance), caffeinated drinks and alcohol and artificial sweeteners like sorbitol.
• Over-the-Counter Medications: You can take over-the-counter anti-diarrheal medications such as loperamide, Bismuth subsalicylate if appropriate for you. Follow the recommended dosage.

Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down or lie down immediately to prevent falling. Keep your head still and close your eyes if needed.
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
• Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
• Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Warning & Precautions

Pregnancy

Contraindicated

Human and animal studies have indicated that the use of telmisartan (one of the components in this medicine) has shown to cause fetal harm. Therefore, Metosartan 50mg Tablet is not recommended for use in pregnant women. If you are pregnant or think you may be pregnant consult your doctor for advice.

Breastfeeding

Contraindicated

Metosartan 50mg Tablet is not recommended for use in breastfeeding women. Animal studies suggest that Telmisartan is excreted in breast milk and can lead to potential adverse effects on the lactating neonate. Therefore, consult your doctor before taking this medicine.

Driving and Using Machines

Use with Caution

Do not drive or operate machines if you feel dizzy or tired after taking Metosartan 50mg Tablet

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking Metosartan 50mg Tablet since it may aggravate the low blood pressure.

Kidney

Consult your doctor

Metosartan 50mg Tablet is not recommended for use if have impaired kidney function and managed with a blood pressure lowering medicine containing aliskiren. It should be used with caution if you have certain kidney disease such as renal artery stenosis (narrowing of the blood vessels to one or both kidneys) or have undergone kidney transplant. Proper dose adjustments and careful monitoring are required in such patients. Therefore, if you have any pre-existing kidney diseases, inform your doctor as a precaution before taking this medicine.

Liver

Consult your doctor

Metosartan 50mg Tablet is not recommended for use in patients with severe liver problems such as cholestasis or biliary obstruction (disease causing difficulty in drainage of the bile from the liver and gall bladder). It should be used with caution in patients with liver diseases such as hepatic impairment. Talk to your doctor as a precaution.

Allergy

Contraindicated

Metosartan 50mg Tablet is not recommended for use if you are allergic to metoprolol, telmisartan or any other ingredients of this medicine.

Lungs

Use with Caution

Metosartan 50mg Tablet should be used with caution in patients bronchospastic disease (disease causing tightening of airway muscles) such as asthma, emphysema, chronic obstructive pulmonary disease or lung infections. Therefore, inform your doctor before taking Metosartan 50mg Tablet if you have any lung related problems.

Heart Disease

Consult your doctor

METOSARTAN 50MG TABLET is not recommended for use in patients with heart disease such as:

• severe bradycardia (low heart rate)
• heart block greater than first degree (condition in which heart beats very slowly or in abnormal rhythm),
• cardiogenic shock (sudden life-threatening condition in which heart fails to pump sufficient blood in the body)
• decompensated cardiac failure (inability of heart to accommodate and/or eject sufficient blood)
• ischemic heart disease (low blood supply to heart muscles)
• Sick sinus syndrome (disorder of heart’s natural pacemaker).

Therefore, before taking Metosartan 50mg Tablet inform your doctor if you any of the above-mentioned heart complications.

Use In Pediatrics

Contraindicated

Metosartan 50mg Tablet is not recommended for use in children and adolescents (aged below 18 years). Animal studies in young rats have shown that high doses may affect kidney development and function. These studies indicated potential adverse effects, including reduced renal perfusion and delayed renal maturation. Consult your doctor before taking Metosartan 50mg Tablet

Use In Geriatrics

Use with Caution

Metosartan 50mg Tablet should be used with caution in elderly patients (aged 65 years and above). Regular monitoring of renal and liver function tests are advised to such patients.

Other Warnings for METOSARTAN 50MG TABLET

Before taking Metosartan 50mg Tablet, inform your doctor if you:           

• Have pheochromocytoma (tumour of adrenal glands located on the kidneys)
• Have diabetes or hypoglycaemia (low blood sugar levels)
• Have history of anaphylactic reactions (signs include itching and flushed or pale skin, low blood pressure, nausea, vomiting)
• Have thyrotoxicosis (too high thyroid levels in the blood)
• Have peripheral vascular disease (flow to limbs due to narrowing of vessels)
• Raised aldosterone levels (water and salt retention in the body along with imbalance of various blood minerals)
• Low blood pressure due to dehydration (excessive loss of water from the body)
• Have deficiency of salt due to diuretic therapy (water tablets), low-salt diet, diarrhoea or vomiting
• Have elevated potassium levels in the blood

Who should not take [GBNKEYWORD

• Those who are allergic to metoprolol and telmisartan
• Patients with other heart complication apart from hypertension, heart failure, etc.
• If you are planned for non-cardiac surgery

Safety Advice

• Always take METOSARTAN 50MG TABLET exactly as advised by your doctor to effectively manage hypertension.
• Regularly check your blood pressure at home to ensure the medication is working effectively.
• Do not stop taking METOSARTAN 50MG TABLET abruptly, as it may cause a sudden rise in blood pressure or other complications.
• Drink plenty of fluids, especially in hot weather, to prevent dehydration, which can lower blood pressure excessively.
• Limit salt intake and follow a balanced, heart-healthy diet for optimal results. Avoid potassium-rich foods (e.g., bananas, oranges) unless advised otherwise, as Telmisartan may increase potassium levels.
• Avoid alcohol consumption while on this medication, as it can increase drowsiness and dizziness.
• Avoid Driving or Heavy Machinery: it may cause dizziness or fatigue, especially when starting the treatment. Avoid tasks requiring alertness until you know how it affects you.
• Not recommended for use during pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking this medication.
• Seek immediate medical attention if you accidentally take more than the prescribed dose, as it may cause severe dizziness, fainting, or a slow heartbeat.
• Start with a lower dose if prescribed for elderly patients, as they are more susceptible to side effects like hypotension and dizziness.
• Visit your doctor for regular blood tests to monitor potassium levels, kidney function, and overall response to the medication.

Diet and Lifestyle Advice

Diet & Nutrition: Best Foods for Heart Health

A heart-healthy diet plays a crucial role in managing high blood pressure and preventing heart diseases. Incorporate these foods into your daily meals for better cardiovascular health:

• Leafy Greens (Spinach, Kale, Lettuce) – Rich in potassium, helping balance sodium levels and lower BP.
• Berries (Blueberries, Strawberries) – Packed with antioxidants that reduce inflammation and improve circulation.
• Fatty Fish (Salmon, Mackerel) – High in omega-3 fatty acids, which lower bad cholesterol and protect the heart.
• Nuts & Seeds (Almonds, Walnuts, Flaxseeds) – Provide healthy fats and help regulate blood pressure.
• Whole Grains (Oats, Brown Rice, Quinoa) – Help reduce cholesterol levels and improve heart function.
• Dark Chocolate (in moderation) – Contains flavonoids that improve blood flow and lower BP.
• Olive Oil – A heart-friendly fat that reduces inflammation and supports artery health.
• Legumes & Beans – Provide plant-based protein and fiber, reducing the risk of heart disease.

Avoid: Processed foods, excess salt, sugary beverages, and trans fats to maintain a healthy heart.

Exercise Tips: Safe Workouts for High BP Patients

Regular physical activity helps control blood pressure, strengthens the heart, and improves overall well-being. Safe workouts for hypertension patients include:

Brisk Walking (30 mins/day) – A low-impact exercise that boosts circulation and lowers BP.

Cycling (indoor or outdoor) – Enhances heart function without putting excessive strain on joints.

Swimming – A full-body workout that improves cardiovascular endurance.

Yoga & Meditation – Helps reduce stress and stabilize blood pressure levels.

Dancing – A fun and effective way to improve heart health and maintain weight.

Strength Training (light weights or resistance bands) – Enhances muscle strength without overburdening the heart.

Avoid: High-intensity exercises, heavy lifting, and sudden exertion, as they may spike BP levels. Always warm up before exercise and consult your doctor before starting a new fitness routine.

Metosartan 50mg Vs. Telma, Betaloc, Atenolol:

Metosartan 50mg offers a dual benefit of heart rate control and blood pressure management, making it a preferred choice for patients with hypertension and cardiovascular risks.

Metosartan & Exercise: What You Should Know

Exercise is essential for controlling blood pressure and improving heart health, but when taking Metosartan, keep these points in mind:

• Best Exercises: Walking, cycling, swimming, yoga, and light strength training help improve circulation and reduce BP.
• Avoid: High-intensity workouts, heavy weightlifting, and sudden exertion, as Metosartan lowers heart rate, making intense activities harder.
• Stay Hydrated: Some patients experience dizziness due to blood pressure changes—drink enough water and take breaks as needed.
• Timing Matters: If you feel weak or dizzy, adjust your exercise schedule around medication intake.
• Monitor BP & Heart Rate: Keep track of your heart rate and blood pressure, especially if starting a new workout routine.

Consult your doctor before making significant changes to your fitness routine while on Metosartan.

Metosartan 50mg vs Metosartan 50 AM: What’s the Difference?

Metosartan 50 AM provides longer-lasting effects due to its extended-release Metoprolol, making it a good choice for once-daily dosing.

What Are the Advantages of Metosartan 50mg Over Other BP Medicines?

• Dual Action: Combines Telmisartan (ARB) and Metoprolol (Beta-blocker) for better blood pressure and heart rate control.
• Heart Protection: Reduces heart strain, heart attacks, stroke, and heart failure better than ARBs or beta-blockers alone.
• Kidney Benefits: Telmisartan helps protect kidney function, especially in diabetic or hypertensive nephropathy patients.
• Stable Blood Pressure: Works better than Atenolol or Metoprolol alone, as it prevents BP spikes and heart rate fluctuations.

Flexible Dosing: Available in regular and extended-release (AM) versions, offering choices for better BP management

Drug - Drug interaction

1. Interactions with Antihypertensive Medications

Other RAAS Inhibitors (e.g., ACE inhibitors or ARBs): Co-administration can increase the risk of hyperkalemia, kidney dysfunction, or hypotension. Regular monitoring of potassium levels and renal function is recommended.

Diuretics (e.g., Furosemide, Hydrochlorothiazide): Co-administration may lead to an excessive drop in blood pressure, especially after the first dose, due to synergistic antihypertensive effects.

2. Interactions with Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

Drugs like Ibuprofen, Naproxen, or Aspirin can reduce the antihypertensive effect of this tablet

Long-term use of NSAIDs with Telmisartan can impair renal function and increase the risk of renal failure, particularly in elderly patients or those with existing kidney disease.

3. Interactions with Antidiabetic Medications

Telmisartan may enhance the blood sugar-lowering effects of insulin or oral antidiabetic drugs, increasing the risk of hypoglycemia.

Metoprolol can mask symptoms of hypoglycemia, such as tachycardia, which may delay treatment in diabetic patients.

4. Interactions with Drugs Affecting Potassium Levels

Potassium-Sparing Diuretics (e.g., Spironolactone, Amiloride) or Potassium Supplements:
Telmisartan may increase potassium levels, leading to hyperkalemia, a condition characterized by muscle weakness, fatigue, and irregular heart rhythms.

5. Interactions with Calcium Channel Blockers

Amlodipine or other calcium channel blockers combined with Metoprolol may result in an additive effect, leading to severe bradycardia, hypotension, or dizziness.

6. Interactions with Antiarrhythmic Drugs

Amiodarone or Digoxin: Metoprolol’s beta-blocking properties may increase the risk of severe bradycardia or conduction disturbances. Digoxin levels should be monitored, as they may rise due to Telmisartan.

7. Interactions with CNS Depressants

Sedatives, antidepressants (e.g., SSRIs), or antipsychotics: Metoprolol may amplify the sedative effects of these drugs, causing excessive drowsiness, fatigue, or dizziness.

8. Interactions with Lipid-Lowering Medications

Statins (e.g., Atorvastatin, Rosuvastatin): Metoprolol metabolism may be affected, increasing the risk of muscle pain or rhabdomyolysis.

Synopsis

More Information

Relevant Health Articles

Ayurveda For Hypertension: Excellent Natural Remedies To Reduce High Blood Pressure

Exercising With High Blood Pressure: What To Do And Avoid, Benefits, And Side Effects

FAQs About METOSARTAN 50MG TABLET

References

1. Metoprolol Succinate Extended-Release Tablets. U. S. Food and Drug Administration. [Revised in March 2006]. [Accessed on 5th March 2025].
2. Telmisartan Tablets. Prescribing information. U.S. Food and Drug Administration. [Revised in May 2011]. [Accessed on 5th March 2025].
3. Telmisartan and Metoprolol Succinate Extended Release Tablets. Blue cross Labs. [Revised in May 2021]. [Accessed on 5th March 2025].
4. Taj Pharma Pvt Ltd. Telmisartan and Metoprolol Succinate Extended Release Tablets. [Accessed on 5th March 2025].

Useful Diagnostic Tests

• Cardiac Risk Profile
• Lipid Profile
• Kidney Function Test

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 06 Mar 2025 | 10:44 AM(IST)