Metosartan 25mg Tablet 10'S

Introduction About METOSARTAN 25MG TABLET

What is Metosartan 25mg Tablet 10's?

Metosartan 25mg Tablet is a fixed-dose combination that combines Metoprolol and Telmisartan. It is commonly advised in cases where individuals are managing their blood pressure levels under clinical supervision. This dual-action formulation supports heart health and vascular function.

Metosartan 25mg Tablet is a combination of Beta-blocker and Angiotensin Receptor Blocker (ARB). Usually used under clinical guidance for cardiovascular wellness. Each tablet contains Metoprolol Succinate 25mg and Telmisartan 40mg. It is a convenient once-daily dosage (as directed by your healthcare provider).

Always follow the dosage recommended by your healthcare expert. Typically advised to be taken with or without food, preferably at the same time each day. Swallow whole with water.

The most common side effects of taking Metosartan 25mg are dizziness or tiredness. Consult your doctor if any of the side effects persist.

Store Metosartan 25mg Tablet below 30°C in a dry place, away from sunlight. Keep out of reach of children. Do not discontinue without consulting a healthcare provider.

Key Composition

1. Metoprolol Succinate (25 mg)

• Class: Beta-1 selective beta-blocker
• Function: Helps manage elevated blood pressure and reduces the strain on the heart by slowing the heart rate and decreasing cardiac output

2. Telmisartan (Unspecified strength in 25mg variant, often 40 mg)

• Class: Angiotensin II Receptor Blocker (ARB)
• Function: Relaxes blood vessels by blocking angiotensin II receptors, making it easier for blood to flow

Uses Of METOSARTAN 25MG TABLET

• Used to manage high blood pressure (Hypertension)

Key highlights of Metosartan 25mg Tablet:

• Combination of Beta-blocker and Angiotensin Receptor Blocker (ARB)
• Used under clinical guidance for cardiovascular wellness
• Each tablet contains Metoprolol Succinate 25mg + Telmisartan 40mg
• Convenient once-daily dosage (as directed by your healthcare provider)

Benefits of METOSARTAN 25MG TABLET

1. Supports blood pressure management

• Metosartan 25mg combines two active ingredients which work together to help support blood pressure control when used regularly under medical supervision

2. Reduces daily pill burden

• Instead of taking two separate medicines, this combination tablet simplifies your routine, which can encourage better medication consistency over time

3. Helps the heart work more efficiently

• By easing strain on the heart and allowing smoother blood flow, Metosartan supports cardiovascular health as part of a medically supervised routine

4. Convenient once-daily use

• Designed to be taken once a day, it fits easily into your daily schedule, ideal for people with busy lifestyles

5. Suitable for long-term use as directed

• This tablet is commonly prescribed as part of a long-term care plan. Its dual-action approach may support overall health management goals

6. Patient-Friendly Formulation

• Formulated to help manage multiple health parameters through a single tablet, making it easier to follow your doctor's plan

How METOSARTAN 25MG TABLET Works

How does Metosartan 25mg work in blood pressure control

1. Metoprolol Succinate (25 mg) - A Beta-1 Selective Blocker:

• Role: Helps manage the heart rate and reduces the force of heart contractions
• Impact: This may support reduced workload on the heart and promote more efficient circulation throughout the body

2. Telmisartan – An Angiotensin II Receptor Blocker (ARB):

• Role: Helps relax and widen the blood vessels by blocking certain natural chemicals in the body
• Impact: When blood vessels stay relaxed, blood can flow more easily, aiding in blood pressure management

3. Dual-Action Mechanism:

This dual approach supports blood pressure regulation by:

• Managing heart activity through Metoprolol
• Relaxing blood vessels through Telmisartan

How to use METOSARTAN 25MG TABLET

• Always follow the dosage recommended by your healthcare expert
• Typically advised to be taken with or without food, preferably at the same time each day, Swallow whole with water
• Do not crush, chew, or break the tablet unless advised by a doctor

How to take Metosartan 25mg tablet safely?

• Take the tablet once daily, preferably at the same time each day to maintain consistency
• Do not adjust the dose on your own, always consult your doctor before making changes

Can Metosartan 25mg be taken on an empty stomach?

• Yes, Metosartan 25mg Tablet can usually be taken with or without food, unless your doctor advises otherwise
• Taking it with food may help if you experience mild stomach discomfort

What if I forgot to take METOSARTAN 25MG TABLET

• If you miss a dose take it as soon as you remember
• If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule
• Do not take a double dose to make up for the missed one, as this may increase the risk of side effects

Overdose

• Symptoms of overdose include severe dizziness, excessive drop in blood pressure, low or irregular heartbeat and breathing difficulties
• In case of an overdose, seek immediate medical attention or call a poison control center

Side Effects Of METOSARTAN 25MG TABLET

Common side effects:

• dizziness
• tiredness

When to consult your doctor?

• Sepsis (a life-threatening severe infection occurring due to damage of whole-body immune response)
• Angioedema (rapid and serious swelling of the skin and mucosa)

How To Manage Side Effects

Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down or lie down immediately to prevent falling. Keep your head still and close your eyes if needed
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up

Tiredness

• Drinking enough water throughout the day helps support circulation and energy levels
• Aim for 7–8 hours of restful sleep each night
• Mild exercises like walking, stretching, or yoga can boost natural energy
• If tiredness persists or affects your daily routine, speak to your healthcare provider

Warning & Precautions

Pregnancy

Contraindicated

Human and animal studies have indicated that the use of telmisartan (one of the components in this medicine) has shown to cause fetal harm. Therefore, Metosartan 25mg is not recommended for use in pregnant women. If you are pregnant or think you may be pregnant consult your doctor for advice.

Breastfeeding

Contraindicated

Metosartan 25mg is not recommended for use in breastfeeding women. Animal studies suggest that Telmisartan is excreted in breast milk and can lead to potential adverse effects on the lactating neonate. Therefore, consult your doctor before taking this medicine.

Driving and Using Machines

Use with Caution

Do not drive or operate machines if you feel dizzy or tired after taking Metosartan 25mg.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking Metosartan 25mg since it may aggravate the low blood pressure.

Kidney

Consult your doctor

Metosartan 25mg is not recommended for use if have impaired kidney function and managed with a blood pressure lowering medicine containing aliskiren. It should be used with caution if you have certain kidney disease such as renal artery stenosis (narrowing of the blood vessels to one or both kidneys) or have undergone kidney transplant.

Liver

Consult your doctor

Metosartan 25mg is not recommended for use in patients with severe liver problems such as cholestasis or biliary obstruction (disease causing difficulty in drainage of the bile from the liver and gall bladder). It should be used with caution in patients with liver diseases such as hepatic impairment.

Allergy

Contraindicated

Metosartan 25mg is not recommended for use if you are allergic to metoprolol, telmisartan or any other ingredients of this medicine.

Lungs

Use with Caution

Metosartan 25mg should be used with caution in patients bronchospastic disease (disease causing tightening of airway muscles) such as asthma, emphysema, chronic obstructive pulmonary disease or lung infections.

Heart Disease

Consult your doctor

Metosartan 25mg is not recommended for use in patients with heart disease such as severe bradycardia (low heart rate), heart block greater than first degree, cardiogenic shock, decompensated cardiac failure or sick sinus syndrome. It should be used with caution in patients having heart trouble.

Use In Pediatrics

Contraindicated

Metosartan 25mg is not recommended for use in children and adolescents (aged below 18 years). Animal studies in young rats have shown that high doses may affect kidney development and function. These studies indicated potential adverse effects, including reduced renal perfusion and delayed renal maturation.

Use In Geriatrics

Use with Caution

Metosartan 25mg should be used with caution in elderly patients (aged 65 years and above). Regular monitoring of renal and liver function tests is advised.

Other Warnings for METOSARTAN 25MG TABLET

Before taking Metosartan 25mg, inform your doctor if you:

• have pheochromocytoma
• have diabetes or hypoglycaemia
• have history of anaphylactic reactions
• have thyrotoxicosis
• have peripheral vascular disease
• raised aldosterone levels
• low blood pressure due to dehydration
• have deficiency of salt due to diuretic therapy (water tablets), low-salt diet, diarrhoea or vomiting
• have elevated potassium levels in the blood

Who should not take [GBNKEYWORD

Metosartan 25mg is not recommended for use if you:

• Are planned for non-cardiac surgery

Safety Advice

• Always take Metosartan 25mg exactly as advised by your doctor to effectively manage hypertension
• Regularly check your blood pressure at home to ensure the medication is working effectively
• Do not stop taking Metosartan 25mg abruptly, as it may cause a sudden rise in blood pressure or other complications
• Drink plenty of fluids, especially in hot weather, to prevent dehydration, which can lower blood pressure excessively
• Limit salt intake and follow a balanced, heart-healthy diet for optimal results. Avoid potassium-rich foods (e.g., bananas, oranges) unless advised otherwise, as Telmisartan may increase potassium levels
• Avoid alcohol consumption while on this medication, as it can increase drowsiness and dizziness
• Avoid Driving or Heavy Machinery: it may cause dizziness or fatigue, especially when starting the treatment. Avoid tasks requiring alertness until you know how it affects you
• Not recommended for use during pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking this medication
• Seek immediate medical attention if you accidentally take more than the prescribed dose, as it may cause severe dizziness, fainting, or a slow heartbeat
• Start with a lower dose if prescribed for elderly patients, as they are more susceptible to side effects like hypotension and dizziness
• Visit your doctor for regular blood tests to monitor potassium levels, kidney function, and overall response to the medication

Drug - Drug interaction

1. Interactions with Antihypertensive Medications

• Other RAAS Inhibitors (e.g., ACE inhibitors or ARBs): Co-administration can increase the risk of hyperkalemia, kidney dysfunction, or hypotension. Regular monitoring of potassium levels and renal function is recommended
• Diuretics (e.g., Furosemide, Hydrochlorothiazide): Co-administration may lead to an excessive drop in blood pressure, especially after the first dose, due to synergistic antihypertensive effects

2. Interactions with Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

• Drugs like Ibuprofen, Naproxen, or Aspirin can reduce the antihypertensive effect of this tablet
• Long-term use of NSAIDs with Telmisartan can impair renal function and increase the risk of renal failure, particularly in elderly patients or those with existing kidney disease.

3. Interactions with Antidiabetic Medications

• Telmisartan may enhance the blood sugar-lowering effects of insulin or oral antidiabetic drugs, increasing the risk of hypoglycemia.
• Metoprolol can mask symptoms of hypoglycemia, such as tachycardia, which may delay treatment in diabetic patients

4. Interactions with Drugs Affecting Potassium Levels

• Potassium-Sparing Diuretics (e.g., Spironolactone, Amiloride) or Potassium Supplements:
• Telmisartan may increase potassium levels, leading to hyperkalemia, a condition characterized by muscle weakness, fatigue, and irregular heart rhythms.

5. Interactions with Calcium Channel Blockers

• Amlodipine or other calcium channel blockers combined with Metoprolol may result in an additive effect, leading to severe bradycardia, hypotension, or dizziness.

6. Interactions with Antiarrhythmic Drugs

• Amiodarone or Digoxin: Metoprolol’s beta-blocking properties may increase the risk of severe bradycardia or conduction disturbances. Digoxin levels should be monitored, as they may rise due to Telmisartan.

7. Interactions with CNS Depressants

• Sedatives, antidepressants (e.g., SSRIs), or antipsychotics: Metoprolol may amplify the sedative effects of these drugs, causing excessive drowsiness, fatigue, or dizziness.

8. Interactions with Lipid-Lowering Medications

• Statins (e.g., Atorvastatin, Rosuvastatin): Metoprolol metabolism may be affected, increasing the risk of muscle pain or rhabdomyolysis.

Synopsis

More Information

Metosartan 25 vs 50  - What is the difference?

Expert insights:

• Studies suggest that the combination of beta-blockers with ARBs may offer complementary benefits for cardiovascular wellness. A healthcare provider may recommend Metosartan when monotherapy does not yield optimal results
• Always rely on personalized consultation before making decisions
• Metosartan 25mg Tablet 10’s is available at licensed online pharmacies with valid prescription verification protocols.

FAQs About METOSARTAN 25MG TABLET

References

1. KD. Tripathi. Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page-561, 563.

2. Jaekyu Shin, Marco Gonzales, and Mark J Pletcher. Risk of Emergent Bradycardia Associated with Initiation of Immediate- or Slow-Release Metoprolol. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed Central. June 2013. [Accessed on 17 May 2025] 

3. Accord Healthcare. Electronic Medicine Compendium (EMC). [Revised in July 2021] [Accessed on 17 May 2025] 

4. AstraZeneca AB. Food and Drug Administration (FDA). [Revised in March 2006] [Accessed on 17 May 20252] 

5. Camber Pharmaceuticals, Inc. Metoprolol Succinate Extended-Release Tablets. [Revised in November 2020] [Accessed on 17 May 2025] 

Useful Diagnostic Tests

• Cardiac Risk Profile
• Lipid Profile
• Kidney Function Test

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 17 May 2025 | 10:43 PM(IST)