Metolar XR 25mg Capsule 15'S

Introduction About METOLAR XR 25MG CAPSULE

Metolar XR 25 Capsule is a beta-blocker that contains Metoprolol that is used to manage high blood pressure (hypertension), chest pain due to angina and irregular heart rhythms (arrhythmias). This medication also helps to reduce future heart attacks, strokes, and migraines. Metolar XR 25 works by slowing the heart rate and decreasing the heart’s workload, making it easier for the heart to pump blood. It is commonly prescribed when long-term heart and blood pressure management is needed and is suitable for daily use under medical supervision.

Metolar XR 25 Capsule can be prescribed on its own or alongside other medications, depending on your specific condition. The dosage and frequency will be determined based on the reason for its use and the severity of your symptoms. It can be taken with or without food, but it is important to take it at the same time every day for the best results. While it may take a few weeks to experience the full benefits, continued use is often necessary, sometimes for life. Even if you feel fine, do not stop taking the medication without medical advice, as high blood pressure often has no noticeable symptoms, and stopping the management could worsen your condition.

Common side effects include tiredness, headache, depression, diarrhea, rash, slow heart rate, dizziness, nausea, tiredness, drowsiness, constipation, fluid retention (swelling), weight gain, palpitations. These side effects are generally mild and temporary. However, some individuals may experience shortness of breath or low blood pressure. To minimize the risk of side effects, your doctor is likely to begin management with a low dose and gradually increase it. If any side effects persist or become bothersome, it is important to consult your doctor.

Before taking this medicine, inform your doctor if you have any liver problems. It may not be appropriate for individuals with a slow heart rate, serious circulation problems, severe heart failure, or low blood pressure. If you are pregnant or breastfeeding, consult your doctor before taking this medication. It is important to discuss your medical history to ensure this medicine is safe for you. Regular monitoring of your blood pressure is recommended to ensure the management is effective. Additionally, avoid alcohol, as it may heighten the risk of certain side effects.

Uses Of METOLAR XR 25MG CAPSULE

• High blood pressure (hypertension)
• Angina (chest pain)
• Arrhythmias (irregular heart rhythms)
• Heart attacks
• Strokes
• Migraines

Benefits of METOLAR XR 25MG CAPSULE

01) Supports control of high blood pressure for sustained cardiovascular wellness:
Metolar XR 25 is highly effective in managing high blood pressure by slowing down the heart rate and reducing the heart's workload. This helps lower the pressure within blood vessels, protecting against long-term complications like stroke, heart failure, and kidney damage when used consistently under medical supervision.

02) Aids in managing angina pectoris (chest discomfort associated with heart conditions):
This medication relieves chest discomfort caused by angina by improving blood flow to the heart and decreasing oxygen demand. Regular use can help reduce the frequency and severity of angina attacks, enhancing overall quality of life for those with coronary artery disease.

03) Contributes to heart failure management by supporting heart function:
Metolar supports heart function in individuals with heart failure. By easing the strain on the heart and promoting more efficient pumping, it improves symptoms such as fatigue and breathlessness, while reducing the likelihood of hospitalization or disease progression.

04) Helps maintain regular heart rhythms and address arrhythmias or palpitations:
It helps stabilize the heart rhythm in cases of arrhythmia or palpitations. By regulating electrical impulses in the heart, Metolar XR 25 minimizes episodes of rapid or irregular heartbeats, improving both comfort and safety in patients with rhythm disorders.

05) Assists in the overall care following heart attack events:
Metolar XR 25 is commonly prescribed after a heart attack to helps to reduce future cardiac events. It reduces the heart’s workload and oxygen demand, helping protect weakened heart tissue and supporting recovery.

06) Supports reduction of migraine headache frequency and intensity:
Though primarily a heart medication, Metolar XR 25 has been found effective in reducing the frequency and severity of migraine attacks. It works by affecting the blood flow in the brain and stabilizing vascular responses that trigger migraines.

07) Extended-release formulation ensures steady absorption over 24 hours:
The extended-release design ensures a steady release of Metoprolol over 24 hours, providing consistent control of symptoms and blood pressure throughout the day without frequent dosing.

08) Convenient once-daily dosage enhances adherence:
With its once-daily administration, Metolar XR 25 offers convenience and improves adherence, especially for those managing chronic heart conditions who are on multiple medications.

How METOLAR XR 25MG CAPSULE Works

Metolar XR 25 Tablet contains Metoprolol, a beta-blocker that helps manage heart-related conditions by affecting the heart and circulation. It works by slowing down the heart rate and reducing the heart’s workload, allowing the heart to pump more efficiently.

Role in Blood Pressure Control:
Metoprolol blocks specific receptors in the heart and blood vessels, which helps lower blood pressure by reducing the force and rate at which the heart beats. This eases the pressure on blood vessel walls and helps to manage complications like strokes and heart attacks.

Managing Angina (Chest Pain):
By decreasing the heart’s oxygen demand, Metolar XR 25 reduces episodes of chest pain caused by reduced blood flow to the heart muscles. This helps improve comfort and physical activity tolerance in people with angina.

Regulating Heart Rhythm:
Metoprolol stabilizes irregular heartbeats (arrhythmias) by controlling electrical signals in the heart. This helps maintain a steady heart rhythm, managing symptoms like palpitations, dizziness, or fainting.

Supporting Heart Failure:
In cases of heart failure, Metolar XR 25 lessens the strain on the weakened heart muscle, allowing it to pump blood more effectively. This can improve symptoms like fatigue and shortness of breath.

How Metoprolol is Processed in the Body:

Once taken, Metoprolol is gradually absorbed into the bloodstream through the digestive system. The extended-release formulation ensures a steady delivery over 24 hours, providing consistent therapeutic effects. The medication is then metabolized mainly by the liver and excreted from the body.

How to use METOLAR XR 25MG CAPSULE

Follow your doctor's instructions regarding the exact dosage. Do not exceed the recommended daily dosage.

Recommended Dosage for Metolar XR 25mg Capsule

The dosage of Metolar XR 25mg depends on the condition being managed and your individual response. Your doctor will prescribe the appropriate dose and may adjust it over time. Typically, the starting dose is low and gradually increased to achieve the best results with minimal side effects.

How to Take Metoprolol Succinate Extended-Release Capsules

• Take the capsule whole with water; do not crush or chew.
• It can be taken with or without food.
• Swallow the capsule at the same time each day to maintain consistent blood levels of the medication.

Timing and Frequency of Metolar XR Administration

• Metolar XR is usually taken once daily due to its extended-release formula.
• Taking it at the same time each day helps maximize effectiveness and reduce the risk of missed doses.

Important Directions for Safe Use

• Do not stop taking Metolar XR suddenly without consulting your doctor, as this may worsen your condition.
• Inform your doctor about any other medications or supplements you are taking to avoid interactions.
• If you miss a dose, take it as soon as you remember unless it is near the time for your next dose. Do not double the dose.

What to Expect When Taking Metoprolol XR Daily

• It may take several weeks before you notice the full benefits.
• You might experience mild side effects initially, which usually improve with time.
• Regular check-ups will help monitor your response and adjust the dose if needed.

Tips for Adhering to Your Metoprolol XR Dosage Schedule

• Use a daily pill organizer or set reminders on your phone.
• Pair medication time with a daily routine activity (e.g., breakfast).
• Keep an extra supply available to avoid running out.

Precautions to Follow While Using Metolar XR Capsules

• Avoid alcohol as it may increase side effects like dizziness or low blood pressure.
• Be cautious when standing up quickly to prevent dizziness or fainting.
• Inform your doctor if you experience symptoms like severe fatigue, shortness of breath, or slow heartbeat.

Important Considerations

Before starting Metolar XR, disclose any existing health conditions such as liver problems, heart issues, or low blood pressure to your doctor. Also, provide a full list of medications you are currently taking. Regular monitoring of blood pressure and heart rate will likely be recommended to ensure safe and effective use of the medication.

Side Effects Of METOLAR XR 25MG CAPSULE

Like all medicines, Metolar XR 25 Capsule may cause certain side effects in some individuals, although not everybody gets them.

The most common side effects of taking Metolar XR 25 Capsule are:

• Tiredness
• Headache
• Depression
• Diarrhea
• Rash
• Slow heart rate
• Dizziness
• Nausea
• Tiredness
• Drowsiness
• Constipation
• Fluid retention (swelling)
• Weight gain
• Palpitations

When To Seek Medical Attention?

• Signs of paradoxical bronchospasm (sudden tightening of the airways after taking the medicine) such as shortness of breath, coughing, and wheezing
• Signs of an allergic reaction such as red itchy welts, swelling of the face, mouth, or tongue, bronchospasm, and rash
• Signs of significant cardiovascular effects such as very slow or irregular heartbeat, severe dizziness, low blood pressure, chest pain, or fainting

How To Manage Side Effects

Diarrhea

• Drink Fluids: Drink clear fluids such as water, broths, and oral rehydration solutions (ORS).
• Electrolytes: If you are losing a lot of fluids (for example, from frequent diarrhea), consider drinking an electrolyte solution to help replenish lost minerals like potassium and sodium.
• BRAT Diet: Try to take Bananas, Rice (white rice), Apple sauce and Toast (plain, without butter) to control diarrhoea management.
• Avoid Certain Foods: While recovering avoid the following food items such as fatty, greasy, or fried foods, spicy foods, dairy products (especially if you have a temporary lactose intolerance), caffeinated drinks and alcohol and artificial sweeteners like sorbitol.
• Over-the-Counter Medications: You can take over-the-counter anti-diarrheal medications such as loperamide, Bismuth subsalicylate if appropriate for you. Follow the recommended dosage.

Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down, or lie down immediately to prevent falling. Keep your head still and close your eyes if needed.
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
• Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
• Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Headache

• Stay Hydrated – Drink plenty of water to reduce dehydration, which can worsen headaches.
• Rest in a Quiet, Dark Room – Avoid bright lights and loud noises to ease headache discomfort.
• Use a Cold or Warm Compress – Apply a cold pack to your forehead or a warm compress to the neck for relief.
• Practice Deep Breathing – Relaxation techniques like deep breathing or meditation can help reduce headache severity.
• Avoid Caffeine and Alcohol – These can trigger or worsen headaches.
• Limit Screen Time – Reduce exposure to screens if headaches are triggered by eye strain.
• Massage Your Temples and Neck – Gentle massages can help relieve tension headaches.
• Take Over-the-Counter Pain Relievers – If needed, mild painkillers like paracetamol (if approved by your doctor) can help.

Nausea And Vomiting

• Eat Small, Frequent Meals: Avoid heavy or greasy foods. Opt for bland foods like crackers, toast, or bananas.
• Stay Hydrated: Sip on clear fluids like water, ginger tea, or electrolyte drinks, Avoid caffeinated and carbonated beverages.
• Ginger: Ginger is a natural remedy for nausea. Try ginger tea, ginger candies, or ginger ale (ensure it contains real ginger).
• Avoid Strong Odors: Minimize exposure to smells that might trigger nausea, such as perfumes or cooking odors.

Warning & Precautions

Pregnancy

Contraindicated

Metolar XR 25 Capsule is not recommended for use in pregnant women. While human studies are limited, animal research has indicated potential harm to the developing baby. Consult your doctor before taking this medication.

Breastfeeding

Contraindicated

Metolar XR 25mg is not recommended while breastfeeding, as Metoprolol may pass into breast milk and affect the nursing infant. However, consult your doctor before taking it while nursing.

Driving and Using Machines

Use with Caution

Metolar XR 25mg may cause dizziness, tiredness, or blurred vision. Avoid driving or operating machinery if you experience these side effects until you feel fully alert and well.

Alcohol

Consult your doctor

Avoid drinking alcohol while taking Metolar XR 25mg, as it may intensify side effects like dizziness and low blood pressure.

Kidney

Use with Caution

Metolar XR 25mg should be used with caution in patients with kidney problems. Consult your doctor before taking this medication.

Liver

Use with Caution

Metolar XR 25mg should be used with caution in patients with liver problems. Consult your doctor before taking this medication.

Allergy

Contraindicated

Do not take Metolar XR 25mg if you are allergic to Metoprolol or any other ingredients in this medicine.

Lungs

Contraindicated

Metolar XR 25mg is not recommended for use in patients with bronchospastic diseases like asthma or COPD. Consult your doctor before taking this medication.

Heart Disease

Consult your doctor

Metolar XR 25mg is not recommended for use in patients with severe bradycardia, low blood pressure, second or third-degree heart block, cardiogenic shock, decompensated cardiac failure, or sick sinus syndrome (unless a permanent pacemaker is present) and should be used with caution in patients with 1st-degree heart block, myocardial infarction, angina pectoris, heart failure, diseases of the heart valve, or enlarged heart muscle. Consult your doctor before taking this medication.

Use In Pediatrics

Contraindicated

Metolar XR 25 mg should only be used in children under medical supervision. The safety and effectiveness of this medicine in pediatric patients have not been fully established. Consult a pediatrician before using this medication in children.

Use In Geriatrics

Use with Caution

Metolar XR 25 mg should be used with caution in elderly patients, particularly those with underlying health conditions such as liver, kidney, or heart problems. Dose adjustments may be necessary. Consult your doctor before use.

Other Warnings for METOLAR XR 25MG CAPSULE

Before taking this medicine, inform your doctor if you have:

• major surgery or anesthesia
• stroke
• diabetes or low blood sugar
• hyperthyroidism
• peripheral vascular disease
• psoriasis

Who should not take [GBNKEYWORD

Metolar XR 25 mg Capsule is not recommended for use if you have:

• severe peripheral arterial disease
• metabolic acidosis
• unmanaged phaeochromocytoma

Drug - Drug interaction

Inform your physician if you are taking any of the following medications before starting Metolar XR 25 mg Capsule:

1. Calcium Channel Blockers (e.g., Verapamil, Diltiazem)
   • Interaction: These drugs, when combined with Metoprolol, may have additive effects on heart rate and cardiac conduction.
   • Effects: Increased risk of bradycardia, heart block, or hypotension.
   • Management: Monitor heart rate and blood pressure closely. Avoid combination or use under strict medical supervision.
2. Clonidine (used for hypertension or migraine prevention)
   • Interaction: Abrupt withdrawal of Clonidine during Metoprolol treatment may cause rebound hypertension.
   • Effects: Sudden rise in blood pressure or hypertensive crisis.
   • Management: If both drugs are being discontinued, withdraw Metoprolol several days before Clonidine to reduce risk.
3. Antidiabetic Drugs (e.g., Insulin, Metformin)
   • Interaction: Metoprolol can mask the symptoms of hypoglycemia (e.g., rapid heartbeat).
   • Effects: Delayed recognition of low blood sugar levels.
   • Management: Monitor blood glucose levels regularly. Educate patients on non-cardiac signs of hypoglycemia (e.g., sweating, hunger).
4. MAO Inhibitors (e.g., Phenelzine, Tranylcypromine)
   • Interaction: Co-administration may result in enhanced hypotensive effects.
   • Effects: Severe low blood pressure or bradycardia.
   • Management: Avoid concurrent use or use with extreme caution under specialist care.
5. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
   • Interaction: NSAIDs may reduce the antihypertensive effect of beta-blockers.
   • Effects: Reduced blood pressure control.
   • Management: Monitor blood pressure regularly; consider alternative pain management options.

Synopsis

More Information

A. Why Choose Metolar XR 25 mg Capsule?

Metolar XR 25 mg Capsule contains Metoprolol, a beta-blocker that helps manage heart-related conditions effectively and safely when used as prescribed. Why it may be a preferred choice:

1. Effective Blood Pressure Control
   Helps lower high blood pressure, reducing the risk of stroke, heart attack, and kidney problems.
2. Heart Protection
   Commonly used in treating angina (chest pain), heart failure, and after a heart attack to improve survival and heart function.
3. Extended-Release Formula
   Provides once-daily dosing for consistent blood levels and better control over 24 hours, enhancing convenience and compliance.
4. Reduces Heart Rate and Strain
   By slowing the heart rate and reducing the workload on the heart, it helps prevent complications in heart disease patients.
5. Proven Safety Profile
   Widely used and studied, with a well-understood safety and efficacy record when taken under medical supervision.
6. Suitable for Long-Term Use
   Can be safely used over the long term under guidance, helping manage chronic cardiovascular conditions effectively.

B. Diet & Lifestyle Considerations While Taking Metolar XR 25 mg Capsule?

FAQs About METOLAR XR 25MG CAPSULE

References

1. K D Tripathi. Cardiovascular drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 523, 545, 564.

2. Bethesda (MD). Metoprolol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubMed, 2006. [Accessed on 11th June 2025] 

3. Aralez Pharmaceuticals US Inc. Metoprolol. [Revised in December 2016] [Accessed on 11th June 2025] 

4. Dr Reddy’s Laboratories Limited. Metoprolol. [Revised in April 2016] [Accessed on 11th June 2025] 

5. STADA Arzneimittel AG. Metoprolol. [Accessed on 11th June 2025] 

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Useful Diagnostic Tests

• Kidney function test (KFT)
• Cardiac Risk Profile

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 12 Jun 2025 | 09:54 AM(IST)