MELADATE Tablet 10's
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Introduction About MELADATE TABLET
MELADATE TABLET contains Melatonin which belongs to the group of medicines called Hormones. It is used to manage jetlag in adults. Jet-lag can be recognized by sleep disturbances, daytime tiredness, fatigue, mild mental impairment, irritability and digestive system disturbances experienced after flying.
Avoid smoking as it may reduce the effect of this medicine and alcohol consumption while taking MELADATE TABLET as it can impair sleep and potentially worsen certain symptoms of jetlag (Ex. headache, morning fatigue and concentration).
MELADATE TABLET should be used with caution in patients with impaired liver or kidney function, epilepsy, autoimmune disease (where the body is attacked by its own immune system), diabetes or impaired glucose tolerance. Consult your doctor before taking it.
MELADATE TABLET is not recommended for use in pregnant women and women of childbearing potential must use effective contraception. MELADATE TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.
MELADATE TABLET is not recommended for use in children and adolescents under 18 years of age. MELADATE TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking it.
The most common side effects of taking MELADATE TABLET are headache and drowsiness. Consult your doctor if any of the side effect worsens or persist for a long period of time.
Uses Of MELADATE TABLET
- Manage jet-lag in adults
How MELADATE TABLET Works
MELADATE TABLET helps to restore the normal day-and-night rhythm by synchronizing the body’s biological day-and-night rhythm as disturbances in biological rhythm may cause sleep disturbances, daytime tiredness, fatigue, mild mental impairment, irritability and other symptoms. Thus MELADATE TABLET helps to restore the normal day-and-night rhythm and reduce the symptoms.
How to use MELADATE TABLET
Take MELADATE TABLET as advised by your doctor. Swallow the whole medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of the medicine depending upon your age, body weight and disease condition.
Side Effects Of MELADATE TABLET
Common
- headache
- drowsiness
Uncommon
- irritability, nervousness, restlessness, abnormal dreams, anxiety
- dizziness
- high blood pressure
- abdominal pain, upper abdominal pain, indigestion, dry mouth, ulceration in mouth, nausea
- itching, rash, dry skin
- feeling unwell
- weight gain
Rare
- mood swings, aggression, increased sex drive
- forgetfulness, restless legs syndrome, tingling or prickling sensation
- watery eyes
- hot flushes
- vomiting, wind, inflammation of the stomach lining, increased salivation, bad breath
- nail disorder
- arthritis, muscle spasms
- increased urination
- prolonged, painful erection, inflammation of prostate gland
- thirst
Stop taking MELADATE TABLET and contact your doctor immediately if you experience any of the following side effects:
- chest pain
- increased risk of bleeding or bruising due to lowered platelet count
- disorientation
- fainting
- blurred vision or other eyesight abnormalities
- pounding heartbeat
- blood in urine
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines if you feel drowsiness. Avoid alcohol consumption as it aggravates drowsiness. Consult your doctor if the symptom does not improve.
Dry Mouth
Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Headache
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Skin rash Or Itching
Avoid hot showers because hot water can irritate the skin further. Do not rub or scratch the affected area. Use sunscreen and protective clothing when going outdoor. Regularly use moisturizers to soothe and hydrate the affected area. If the symptom still persists, consult your doctor.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, inform your doctor.
Warning & Precautions
Pregnancy
ContraindicatedMELADATE TABLET is not recommended for use in pregnant women and women of childbearing potential must use effective contraception. Consult your doctor before taking it.
Breastfeeding
ContraindicatedMELADATE TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel drowsiness and decreased alertness for several hours after taking MELADATE TABLET.
Alcohol
Consult your doctorAvoid alcohol consumption while taking MELADATE TABLET as it can impair sleep and potentially worsen certain symptoms of jetlag (Ex. headache, morning fatigue and concentration).
Kidney
Use with CautionMELADATE TABLET should be used with caution in patients with impaired kidney function. Consult your doctor before taking it.
Liver
Use with CautionMELADATE TABLET should be used with caution in patients with impaired liver function. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take MELADATE TABLET if you are allergic to melatonin or other ingredients of this medicine.
Use In Pediatrics
ContraindicatedMELADATE TABLET is not recommended for use in children and adolescents under 18 years of age. Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionMELADATE TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking MELADATE TABLET.
Others
Before taking MELADATE TABLET, inform your doctor if you have:
- epilepsy
- autoimmune disease (where the body is attacked by its own immune system)
- diabetes or glucose intolerance
- habit of smoking
Interactions
A. Drug-Drug Interactions:
Before taking MELADATE TABLET inform your doctor if you are taking any of following medicines:
- fluvoxamine (used to manage of depression and obsessive-compulsive disorder)
- psoralens (used for managing skin disorders like psoriasis)
- cimetidine (used to manage stomach problems such as ulcers)
- estrogens (used as contraceptives or hormone replacement preparations)
- quinolones, rifampicin (used to manage bacterial infections)
- carbamazepine (used to manage epilepsy)
- benzodiazepines and non-benzodiazepine hypnotics (medicines that induce sleep, Ex. midazolam, temazepam, zaleplon, zolpidem and zopiclone)
- warfarin (used to manage or manage blood clots)
B. Drug-Food Interactions:
Food should not be consumed 2 hours before or 2 hours after taking MELADATE TABLET.
Overdosage:
If you or anyone else accidentally take too much of MELADATE TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage includes drowsiness, headache, dizziness and nausea.
Synopsis
| Drug | : | Melatonin |
| Pharmacological Category | : | Hormones |
| Therapeutic Indication | : | Jet-lag |
| Dosage Forms | : | Tablet, Syrup, Oral Spray, Gel, Lozenges |
More Information
- Keep MELADATE TABLET out of reach of children
- Do not store MELADATE TABLET above 25°C
FAQs About MELADATE TABLET
Q: What is MELADATE TABLET used for?
A: MELADATE TABLET is used to manage jetlag in adults. Jet-lag can be recognized by sleep disturbances, daytime tiredness, fatigue, mild mental impairment, irritability and digestive system disturbances experienced after flying. Consult your doctor before taking it.
Q: Is MELADATE TABLET safe in pregnant women?
A: MELADATE TABLET is not recommended for use in pregnant women and women of childbearing potential must use effective contraception. Consult your doctor for advice before taking it.
Q: Can I drink alcohol while taking MELADATE TABLET?
A: Avoid alcohol consumption while taking MELADATE TABLET as it can impair sleep and potentially worsen certain symptoms of jetlag (Ex. headache, morning fatigue and concentration).
Q: How does MELADATE TABLET work?
A: MELADATE TABLET helps to restore the normal day-and-night rhythm by synchronizing the body’s biological day-and-night rhythm as disturbances in biological rhythm may cause sleep disturbances, daytime tiredness, fatigue, mild mental impairment, irritability and other symptoms. Thus MELADATE TABLET helps to restore the normal day-and-night rhythm and reduce the symptoms.
Q: What are the common side effects of MELADATE TABLET?
A: The most common side effects of taking MELADATE TABLET are headache and drowsiness. Consult your doctor if any of the side effects worsen or persist for a long period of time.
References
1. K.D. Tripathi. Drugs acting on Central Nervous System. Essentials of Medical Pharmacology. 7th edition. 2013. Page 409
2. Rosemary A. Savage, Nowera Zafar, Sandesh Yohannan, John-Mark M. Miller. Melatonin. National Institute of Health. NLM. National Centre for Biotechnology Information. Stat pearls. August 2021. [Accessed on 21st July 2022] https://www.ncbi.nlm.nih.gov/books/NBK534823/
3. Sylvie Tordjman. Sylvie Chokron. Richard Delorme. Annaelle Charrier. Eric Bellissant. Nemat Jaafari. Claire Fougerou. Melantoin. Pharmacology, functions and therapeutic benefits. Current Neuropharmacology. April 2017. [Accessed on 21st July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405617/
4. Rafarm SA. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 21st Jul 2022] https://www.medicines.org.uk/emc/files/pil.10405.pdf
5. Rafarm SA. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 21st July 2022] https://www.medicines.org.uk/emc/files/pil.11967.pdf
Useful Diagnostic Tests
- Polysomnography
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