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Introduction About MEGADINE CREAM
MEGADINE CREAM contains Povidone-Iodine, which belongs to the group of medicines called Broad-spectrum antiseptics. MEGADINE CREAM is used as an antiseptic for the management of minor damage or infection of the skin. It kills harmful infection-causing microorganisms.
It also helps in the management of infection in burns, lacerations, cuts, and abrasions, management of common skin infections, and infection control following circumcision, suture removal, and dressing changes, degerming care of stasis ulcers, decubitus ulcers, and the umbilical area, and in other procedures where degerming is needed.
Before using MEGADINE CREAM, inform your doctor if you have any kind of allergies, if you currently have or have ever had a thyroid problem, if you are currently having lithium therapy for depression, if your skin is broken (for example, due to a burn), or if you currently have, or have ever had, a kidney problem.
MEGADINE CREAM should be used with caution among pregnant and breastfeeding women and the elderly. MEGADINE CREAM is not recommended for use in children less than 2 years of age. The common side effects of using MEGADINE CREAM are burning, irritation, itching, and redness. Consult your doctor if any of your symptoms get worse or persist.
Uses Of MEGADINE CREAM
- Management of minor damage or infection of the skin
How MEGADINE CREAM Works
MEGADINE CREAM contains povidone-iodine. The antimicrobial action of povidone-iodine starts after iodine dissociates from the complex component. Once in the free form, iodine rapidly penetrates microbial cell membranes and interacts with important cell-forming components, like proteins, nucleotides, and fatty acids in the cytoplasm and cytoplasmic membrane and destroys them.
How to use MEGADINE CREAM
Apply MEGADINE CREAM as advised by your physician. It is for external use only. Your doctor will decide the correct dose and duration for you depending on your condition.
Side Effects Of MEGADINE CREAM
Common
- Burning
- irritation
- itching
- redness
Rare
- allergic-type reactions, including a rash or difficulty in breathing
Stop using MEGADINE CREAM and contact your doctor if you experience:
- general allergic reaction symptoms such as rash, redness, itching, and difficulty breathing
How To Manage Side Effects
Skin rash Or Itching
Try to relax and rest for some time after using MEGADINE CREAM. Do not rub the affected area. Consult your doctor if the itching persists.
Warning & Precautions
Pregnancy
Use with CautionMEGADINE CREAM should be used with caution during pregnancy. Consult your doctor before using MEGADINE CREAM.
Breastfeeding
Use with CautionMEGADINE CREAM should be used with caution in breastfeeding women. Consult your doctor before using MEGADINE CREAM.
Driving and Using Machines
SafeMEGADINE CREAM generally does not affect your ability to drive or use machines.
Allergy
ContraindicatedMEGADINE CREAM is not recommended for use if you are allergic to iodine or polyvinylpyrrolidone.
Use In Pediatrics
ContraindicatedMEGADINE CREAM is not recommended in children under two years of age. Consult your doctor for advice before using MEGADINE CREAM.
Use In Geriatrics
Use with CautionMEGADINE CREAM should be used with caution in the elderly. Consult your doctor for advice before using MEGADINE CREAM.
Others
MEGADINE CREAM is not recommended for use if you:
- currently have or ever had a thyroid problem, including swelling (nodular colloid goitre, endemic goitre, or Hashimoto’s thyroiditis)
- are currently having lithium therapy for depression
Before using MEGADINE CREAM, inform your doctor if you:
- have broken skin (for example, due to a burn)
- currently have, or have ever had, a kidney problem
- are due to have a thyroid, faeces (stool), or urine test
Interactions
A. Drug-Drug Interactions:
- medicines used to manage some mental problems (Ex. lithium)
- medicines for the management of thyroid (Ex. thyroxine)
Overdosage:
If you or anyone else accidentally uses too much of MEGADINE CREAM, consult your doctor immediately or visit the nearby hospital. You may experience any of the following symptoms, like stomach pain, being unable to pass urine, loss of appetite, weakness, nausea, vomiting, coughing up blood, excessive sweating, difficulty breathing, metabolic acidosis, anxiety, and pale skin, immediately consult the doctor.
Synopsis
| Drug | : | Povidone-Iodine |
| Pharmacological Category | : | Broad spectrum antiseptic |
| Therapeutic Indication | : | as an antiseptic for small wounds and lacerations |
| Dosage Forms | : | Ointments, Cream, Eye Drops, Gel, Spray, Solution, Gargle, Pessaries, Powder |
More Information
Storage
- Keep the medicine out of reach of children
- Store MEGADINE CREAM at room temperature
FAQs About MEGADINE CREAM
Q: How does MEGADINE CREAM work?
A: MEGADINE CREAM contains povidone-iodine. The antimicrobial action of povidone-iodine starts after iodine dissociates from the complex component. Once in the free form, iodine rapidly penetrates microbial cell membranes and interacts with important cell-forming components, like proteins, nucleotides, and fatty acids in the cytoplasm and cytoplasmic membrane and destroys them.
Q: For how long can I use MEGADINE CREAM?
A: Your doctor might advise you on how long you should continue to use MEGADINE CREAM. You will need to consult your doctor from time to time to review your management and assess your symptoms.
Q: What are the uses of MEGADINE CREAM?
A: MEGADINE CREAM is used to be used in the management of infection in wounds, including cuts, small areas of burn, ulcers, and minor injuries.
Q: What are the side effects of MEGADINE CREAM?
A: The common side effects of using MEGADINE CREAM are burning, irritation, itching, and redness. Consult your doctor if any of your symptoms get worse or persist.
Q: Is MEGADINE CREAM safe for kids?
A: MEGADINE CREAM is not recommended in children under two years of age. Consult your doctor for advice before using it.
Q: Can MEGADINE CREAM be used in pregnant women?
A: MEGADINE CREAM should be used with caution during pregnancy. Consult your doctor before using it.
Q: How should I use MEGADINE CREAM?
A: Apply MEGADINE CREAM as advised by your physician. It is for external use only. Your doctor will decide the correct dose and duration for you depending on your condition.
Q: Who should not use MEGADINE CREAM?
A: MEGADINE CREAM is not recommended for use if you are allergic to iodine or polyvinylpyrrolidone or if you currently have or ever had a thyroid problem, including swelling (nodular colloid goitre, endemic goitre, or Hashimoto’s thyroiditis) or undergoing lithium therapy for depression.
Q: What precautions must be taken while using MEGADINE CREAM?
A: Before using MEGADINE CREAM, inform your doctor if your skin is broken (for example, due to a burn), you currently have, or have ever had, a kidney problem, or you are scheduled for a thyroid, faeces (stool), or urine test.
Q: When to stop using MEGADINE CREAM?
A: Stop using MEGADINE CREAM and contact your doctor if you experience general allergic reaction symptoms such as rash, redness, itching, or difficulty breathing.
References
1. KD Tripathi. Section 14, Antiseptics, Disinfectants, and Ectoparasiticides. Seventh edition. 2013. Page – 897-905.
2. MIMS. Betadine. [Accessed on 13th August 2024] https://www.mims.com/philippines/drug/info/betadine%20cream-ointment?type=full
3. Seton Healthcare Group, Tubiton House, Medlock Street, Oldham, OL1 3HS, UK. Monograph [Revised in July 2019] [Accessed on 13th August 2024] https://www.hpra.ie/img/uploaded/swedocuments/e22c9eeb-0b02-4de4-a874-25fd55af1e45.pdf
4. Sanofi-Aventis New Zealand Limited. Betadine Antiseptic Topical Ointment. [Revised in June 2021] [Accessed on 13th August 2024] https://media.healthdirect.org.au/medicines/GuildLink_Information/29561/CMI/swcboint10621.pdf
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