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Introduction About MEGABURN 60MG TABLET
MEGABURN 60MG TABLET contains Orlistat, which belongs to the group of medicines called Anti-obesity agents. It is used for weight reduction in adults (18 years and above) who are overweight and have a body mass index (BMI) of 28 or more. Obesity is defined as abnormal or excessive fat accumulation that presents a risk to health. A body mass index (BMI) over 25 is considered overweight, and over 30 is obese.
Before taking MEGABURN 60MG TABLET, inform your doctor if you have cholestasis, malnutrition syndrome, diabetes, or kidney disease. MEGABURN 60MG TABLET is not recommended for use in pregnant and breastfeeding women. MEGABURN 60MG TABLET is not recommended for use in children and adolescents (below 18 years of age), therefore consult your doctor before taking the medicine.
The most common side effects of taking MEGABURN 60MG TABLET are flatulence, with or without oily spotting, sudden bowel motions, fatty, oily, or soft stools, and stomach pain. Contact your doctor if any of the above side effects worsen or persists for a long duration.
Uses Of MEGABURN 60MG TABLET
- Used for obesity along with a reduced calorie and lower-fat diet
How MEGABURN 60MG TABLET Works
MEGABURN 60MG TABLET works by attaching to the enzymes in the digestive system (lipases) and managing them from breaking down some of the fat that have consumed during the meal. The fat that is not digested cannot be absorbed and it is removed by the body.
How to use MEGABURN 60MG TABLET
Take MEGABURN 60MG TABLET as advised by the physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on the age, body weight and disease condition. Do not stop taking MEGABURN 60MG TABLET unless your doctor advises you to stop.
Side Effects Of MEGABURN 60MG TABLET
Common
- flatulence with or without oily spotting
- sudden bowel motions
- fatty or oily stools, soft stools
- stomach pain
- fecal incontinence
- runny or liquid stools
- anxiety
- headache
- respiratory tract infection
- low blood sugar levels
- flu infection
- rectal pain or discomfort
- tooth or gum disorders
- urinary tract infection
- irregular periods (women)
- tiredness
Stop taking MEGABURN 60MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (severe breathing problems, sweating, rash, itching, swollen face, rapid heartbeat, nausea, vomiting, feeling unwell)
How To Manage Side Effects

Bloating
Eat smaller meals more frequently. Eat and drink slowly, and exercise regularly. If the symptom does not improve, contact your doctor.

Diarrhea
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

Headache
Drink an ample amount of water. Get adequate rest. Try to be relaxed and stress-free. Ask your doctor before taking any medicine other than MEGABURN 60MG TABLET.

Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.
Warning & Precautions

Pregnancy
ContraindicatedMEGABURN 60MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking the medicine.

Breastfeeding
ContraindicatedMEGABURN 60MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.

Driving and Using Machines
Use with CautionMEGABURN 60MG TABLET is unlikely to affect your ability to drive and use machines. Consult your doctor before taking the medicine.

Kidney
Use with CautionMEGABURN 60MG TABLET should be taken with caution in patients with kidney disease. Consult your doctor before taking the medicine.

Liver
ContraindicatedMEGABURN 60MG TABLET is not recommended for patients with cholestasis (obstruction of bile flow from the liver). Consult your doctor before taking the medicine.

Allergy
ContraindicatedDo not take MEGABURN 60MG TABLET if you are allergic to Orlistat or any other ingredients of this medicine.

Use In Pediatrics
ContraindicatedMEGABURN 60MG TABLET is not recommended for use in children and adolescents (below 18 years of age). Consult your doctor before taking the medicine.
Others
MEGABURN 60MG TABLET is not recommended for use if you:
- have trouble absorbing food (chronic malabsorption syndrome)
Before taking MEGABURN 60MG TABLET, inform your doctor if you:
- have diabetes
Interactions
A. Drug-Drug interactions:
Before taking MEGABURN 60MG TABLET, inform your doctor if you are taking any of the following medicine:
- ciclosporin (used after organ transplant)
- medicines used to thin the blood (Ex. warfarin, clopidogrel)
- oral contraceptives (Ex. ethinyl estradiol, progestin)
- acarbose (used to manage diabetes)
- levothyroxine (used to manage hypothyroidism)
- medicines used to manage epilepsy (Ex. carbamazepine, phenytoin)
- medicines used to manage viral infection (Ex. abacavir, lamivudine)
- medicines used for depression, psychiatric disorders, or anxiousness (Ex. amitriptyline, phenobarbital, fluoxetine)
- medicines used to manage blood pressure (Ex. enalapril, atenolol)
- medicines used to lower cholesterol levels in the blood (Ex. atorvastatin, simvastatin)
Overdosage:
If you or anyone else accidentally takes too much of MEGABURN 60MG TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
Drug | : | Orlistat |
Pharmacological Category | : | Lipase inhibitor |
Therapeutic Indication | : | Obesity |
Dosage Forms | : | Tablet, Capsule |
More Information
- Keep MEGABURN 60MG TABLET out of reach from children
- Do not store above 25°C
FAQs About MEGABURN 60MG TABLET
Q: What is MEGABURN 60MG TABLET used for?
A: It is used for weight reduction in adults (18 years and above) who are overweight and have a body mass index (BMI) of 28 or more. Obesity is defined as abnormal or excessive fat accumulation that presents a risk to health. A body mass index (BMI) over 25 is considered overweight, and over 30 is obese.
Q: Does MEGABURN 60MG TABLET have side effects?
A: Yes, taking MEGABURN 60MG TABLET may cause a few side effects in some individuals like stomach pain, anxiety, tiredness, headache, flatulence with or without oily spotting, sudden bowel motions, inability to control bowel movements, rectal pain or discomfort and may also cause some other systemic effects such as respiratory tract infection, low blood sugar levels, tooth or gum disorders, urinary tract infection or irregular periods in women. Consult your doctor before taking if any of the above side effects persists for a longer duration.
Q: What happens if you take MEGABURN 60MG TABLET before food?
A: MEGABURN 60MG TABLET works on the fat that are taken along with the food, hence it is advisable not to take the medicine if you miss a meal or if there is no fat in one of your meals.
Q: Can MEGABURN 60MG TABLET cause flatulence?
A: Yes. It may cause flatulence, hence it is a common side effect of MEGABURN 60MG TABLET. Eat smaller meals more frequently. Eat and drink slowly, and exercise regularly. If the symptom does not improve, contact your doctor.
Q: Can I take multivitamins with MEGABURN 60MG TABLET?
A: Yes. Take a multivitamin (containing vitamins A, D, E and K) every day if you are taking MEGABURN 60MG TABLET as it can lower the levels of some vitamins absorbed by the body. Take the medicines as told by your physician.
Q: Can I take MEGABURN 60MG TABLET on an empty stomach?
A:Take MEGABURN 60MG TABLET as advised by your physician. It can be taken immediately before, during, or up to an hour after a meal. It should be swallowed with water.
Q: Do I need to follow any diet while taking MEGABURN 60MG TABLET?
A: While taking MEGABURN 60MG TABLET, make sure your three main meals are well balanced, reduced calorie, and low-fat. Eat lower-fat meals to decrease the chance of diet-related management effects. You should choose foods which contain a range of different nutrients and learn to eat healthily in the long run.
Q: For how long should I take MEGABURN 60MG TABLET?
A: Take MEGABURN 60MG TABLET as long as your doctor advises you to take it. It should be taken for no longer than six months. Consult your doctor for advice.
Q: What if I forget to take a dose of MEGABURN 60MG TABLET?
A: If it is less than an hour since your last main meal, take the forgotten dose of MEGABURN 60MG TABLET. If it is more than an hour since your last main meal, do not take the missed dose. Wait and take the next dose around your next meal as usual.
Q: Can MEGABURN 60MG TABLET cause stomach pain?
A: Yes. Stomach pain is a common side effect of MEGABURN 60MG TABLET. Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.
References
1. Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey. Obesity. Pharmacotherapy- A Pathophysiologic Approach. Eighth edition. Page- 2571.
2. Suyog S. Jain, Sunita J. Ramanand, Jaiprakash B. Ramanand, Pramod B. Akat, Milind H. Patwardhan, and Sachin R. Joshi. Evaluation of efficacy and safety of orlistat in obese patients. PMC Pubmed Central. NCBI. National Library of Medicine, National Institute of Health. June 2011. [Accessed on January 10th, 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125014/
3. GlaxoSmithKline. Effect of Orlistat in Body Composition. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in March 2013] [Accessed on January 10th, 2024] https://www.clinicaltrials.gov/ct2/show/NCT00752726
4. Famar S.A. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on January 10th, 2024] https://www.medicines.org.uk/emc/files/pil.6533.pdf
5. Pharmaceutical Works Polpharma SA. Orlistat. [Revised in June 2020] [Accessed on January 10th, 2024] https://products.tevauk.com/mediafile/id/49360.pdf
Useful Diagnostic Tests
- Body Mass Index (BMI)