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Introduction About MEGABROM EYE DROPS
MEGABROM EYE DROPS contains Bromfenac, which belongs to the group of medicines called Non-steroidal anti-inflammatory drugs (NSAIDs). It is used in adults for the management of postoperative inflammation and reduction of postoperative eye pain in patients who have undergone cataract surgery.
Cataract can be defined as a condition in which the lens of the eye becomes progressively opaque or cloudy. Symptoms include blurred vision, sensitivity to light/glare, poor night vision, seeing halos around lights, and double vision.
MEGABROM EYE DROPS should be used with caution in patients having bleeding problems (Ex. haemophilia), rheumatoid arthritis, diabetes, or eye problems (Ex. dry eye syndrome, corneal problems, repeated eye surgery in a short time). Do not wear contact lenses while using the medicine.
MEGABROM EYE DROPS should not be used during the last three months of pregnancy, and your doctor may advise you to use this medicine only if needed. It can be used in breast-feeding women.
MEGABROM EYE DROPS is not recommended for use in children and adolescents. There is no evidence of safety for MEGABROM EYE DROPS in elderly patients above 65 years of age. Consult your doctor before using it.
The most common side effects of using MEGABROM EYE DROPS are increased sensitivity of eyes to light, eye pain, and blurred vision. Consult your doctor if any of the side effects worsen.
Uses Of MEGABROM EYE DROPS
- Manage postoperative inflammation and reduction of postoperative eye pain in patients who have undergone cataract surgery.
How MEGABROM EYE DROPS Works
MEGABROM EYE DROPS effectively blocks the synthesis of certain substances involved in causing inflammation (prostaglandin). Hence reducing the pain and inflammation after the patient has undergone cataract surgery.
How to use MEGABROM EYE DROPS
Use MEGABROM EYE DROPS as advised by your physician. While using MEGABROM EYE DROPS, tilt your head back and pull down your lower eyelid. Make sure you wash your hands and do not touch any surface while using it. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects Of MEGABROM EYE DROPS
Common
- foreign body sensation in the eye
- eye pain
- eye discomfort in bright light (photophobia)
- blurred vision
Uncommon
- discomfort in the eye (redness, inflammation, eye discharge, itching, or irritation)
- damage and inflammation of the surface of the eye
- swelling or bleeding of the eyelid
- moving spots before the eyes, which can indicate damage to the back of the eye (retina)
- swelling of the face
- cough
- nose bleeding or runny nose
Rare
- asthma
How To Manage Side Effects

Eye pain Or Sensitivity
Rest your eyes by closing or sleeping. Avoid bright lights, reading, watching television, and working on the computer. Keep your eyes closed and gently massage your eyes for a few seconds to relieve the muscles.
Warning & Precautions

Pregnancy
Monitoring requiredMEGABROM EYE DROPS should not be used during the last three months of pregnancy. Your doctor may prescribe this medicine during pregnancy only if considered clearly necessary. Consult your doctor before using it.

Breastfeeding
SafeMEGABROM EYE DROPS can be used in breastfeeding women. Consult your doctor before using it.

Driving and Using Machines
ContraindicatedDo not drive or use machines if you experience blurred vision after using MEGABROM EYE DROPS.

Allergy
ContraindicatedDo not use MEGABROM EYE DROPS if you are allergic to Bromfenac or any other ingredients of this medicine.

Lungs
ContraindicatedMEGABROM EYE DROPS is not recommended for use in patients who have experienced asthma due to other non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or diclofenac. Consult your doctor before using it.

Use In Pediatrics
ContraindicatedMEGABROM EYE DROPS is not recommended for use in children and adolescents (under 18 years of age). Consult your child’s doctor for advice.

Use In Geriatrics
Consult your doctorThere is no evidence of safety for MEGABROM EYE DROPS in patients above 65 years of age. Consult your doctor before using it.
Others
MEGABROM EYE DROPS is not recommended for use if you:
- wear contact lenses
- had experienced skin allergy or intense inflammation in your nose when using other non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or diclofenac
Before using MEGABROM EYE DROPS, inform your doctor if you:
- have bleeding problems (Ex. haemophilia)
- have eye problems (Ex. dry eye syndrome, corneal problems)
- have diabetes
- have rheumatoid arthritis
- had repeated eye surgery within a short time span
Interactions
A. Drug-Drug interactions:
Before using MEGABROM EYE DROPS, inform your doctor if you are taking any of the following medicines:
- anti-coagulants (Ex. warfarin, clopidogrel, acetylsalicylic acid) (used to manage or manage blood clots)
- topical steroids (Ex. cortisone) (used to manage various skin conditions)
Overdosage:
If you or anyone else accidentally uses or swallows too much of MEGABROM EYE DROPS, rinse your eye with warm water or drink a glass of warm water if you swallow. Do not put in any more drops until it is time for your next regular dose. Consult your doctor immediately or visit the nearby hospital.
Synopsis
Drug | : | Bromfenac |
Pharmacological Category | : | Nonsteroidal anti-inflammatory drugs (NSAIDs) |
Therapeutic Indication | : | Postoperative inflammation and eye pain after cataract surgery |
Dosage Forms | : | Eye drops, Ophthalmic Solution |
More Information
Storage
- Keep MEGABROM EYE DROPS out of reach of children
- Do not store above 25°C
FAQs About MEGABROM EYE DROPS
Q: Is MEGABROM EYE DROPS a steroid?
A: No, MEGABROM EYE DROPS is not a steroid, it is a non-steroidal anti-inflammatory drug (NSAID) used to manage postoperative inflammation and reduce postoperative eye pain in patients who have undergone cataract surgery.
Q: What happens if I stop using MEGABROM EYE DROPS on my own?
A: Do not stop using MEGABROM EYE DROPS unless recommended by the doctor. In rare cases, there might be a flare-up of the inflammatory response (retina swelling) on withdrawal. Always follow the advice of the doctor to achieve better results.
Q: Does MEGABROM EYE DROPS increase the risk of bleeding?
A: Yes, MEGABROM EYE DROPS can make it difficult for the body to form blood clots, increasing the risk of bleeding. The risk is higher in people who have bleeding disorders like haemophilia. Inform your doctor about your medical history before using it.
Q: How does MEGABROM EYE DROPS work?
A: MEGABROM EYE DROPS effectively blocks the synthesis of certain substances involved in causing inflammation (prostaglandin). Hence reducing the pain and inflammation after the patient has undergone cataract surgery.
Q: Can MEGABROM EYE DROPS be used during pregnancy?
A: MEGABROM EYE DROPS should not be used during the last three months of pregnancy. Your doctor may prescribe this medicine during pregnancy only if considered clearly necessary. Consult your doctor before using it.
Q: What is MEGABROM EYE DROPS used for?
A: MEGABROM EYE DROPS is used in adults for the management of postoperative inflammation and reduction of postoperative eye pain in patients who have undergone cataract surgery.
Q: Who should avoid using MEGABROM EYE DROPS?
A: MEGABROM EYE DROPS is not recommended for use in patients who have experienced asthma due to other non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or diclofenac, or are allergic to Bromfenac, or if you are wearing contact lenses, or had experienced skin allergy or intense inflammation in your nose when using other non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or diclofenac. Consult your doctor before using it.
Q: What precautions must be followed while using MEGABROM EYE DROPS?
A: Before using MEGABROM EYE DROPS, inform your doctor if you have bleeding problems (Ex. haemophilia), eye problems (Ex. dry eye syndrome, corneal problems), diabetes, rheumatoid arthritis, or had repeated eye surgery within a short time span.
Q: Is MEGABROM EYE DROPS safe for kids?
A: MEGABROM EYE DROPS is not recommended for use in children and adolescents (under 18 years of age). Consult your child’s doctor for advice.
Q: How should I use MEGABROM EYE DROPS?
A: Use MEGABROM EYE DROPS as advised by your physician. While using MEGABROM EYE DROPS, tilt your head back and pull down your lower eyelid. Make sure you wash your hands and do not touch any surface while using it. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
References
1. Jeffrey K. Aronson. Bromfenac sodium. Meyler's Side Effects of Drugs. Sixteenth edition. 2016. Page –1053.
2. Arcispedale Santa Maria Nuova-IRCCS. Bromfenac to Reduce Inflammation in Patients With Pseudoexfoliation Syndrome After Cataract Surgery (REPEX). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in October 2014] [Accessed on 13th August 2024] https://clinicaltrials.gov/ct2/show/NCT0213716
3. Bausch & Lomb Incorporated. Efficacy of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in May 2014] [Accessed on 13th August 2024] https://clinicaltrials.gov/ct2/show/NCT01367249
4. Dr. Gerhard Mann. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 13th August 2024] https://www.medicines.org.uk/emc/files/pil.4626.pdf
5. Prolensa-bromfenac sodium solution/drops. DailyMed; National Library of Medicine; National Institute of Health. [Revised in April 2020] [Accessed on 13th August 2024] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=4e072537-f73c-4a96-a65f-e2805ce112d8
6. Bromfenac. NIH National Library of Medicine. MedlinePlus. [Revised in September 2017] [Accessed on 13th August 2024] https://medlineplus.gov/druginfo/meds/a611018.html
Useful Diagnostic Tests
- Retinal exam
- Slit-lamp exam
- Visual acuity test
- Tonometry
- Complete Blood Count (CBC)/ Hemogram
- Kidney Function Test (KFT)
- Serum Electrolytes/ Electrolytes Profile
- Healthy Midlife Checkup
- Full Body Checkup - Gold
- Full Body Checkup – Silver