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Introduction About MARILIV SUSPENSION
MARILIV SUSPENSION contains Silymarin which belongs to the group of medicines called Flavonoids. Silymarin is a flavonoid isolated from the plant species called Silybum marianum which is commonly known as milk thistle. It is indicated for supportive management in chronic liver disease and cirrhosis.
Before taking MARILIV SUSPENSION, inform your doctor if you have allergic to milk thistle or plants of the Asteraceae/Compositae family such as daisies, marigolds, or artichokes.
There are no adequate and well-controlled studies of MARILIV SUSPENSION in pregnancy and lactation. Consult your doctor for advice.
MARILIV SUSPENSION is not recommended in children less than 5 years of age. Consult your doctor for advice.
MARILIV SUSPENSION should be used with caution in elderly patients, consult your doctor for advice.
Generally, MARILIV SUSPENSION is well tolerated, however a few side effects like gastro-intestinal discomfort including anorexia, nausea or diarrhoea and headache may be seen. If any of these side effects worsen, contact your doctor for advice.
Uses Of MARILIV SUSPENSION
- Used for supportive management in chronic liver disease and cirrhosis
How MARILIV SUSPENSION Works
MARILIV SUSPENSION contains Silymarin, is an herbal remedy that has been used for centuries for liver diseases. The hepatoprotective and antioxidant activities of silymarin effectively lowers the oxidative liver damage by inhibiting the formation of free radicals. Silymarin also enhances the cellular regeneration of hepatocytes (liver cells) by stimulating the activity of an enzyme called RNA polymerase. It also improves the overall functional capacity of the liver and aids in metabolism and digestion.
How to use MARILIV SUSPENSION
Take MARILIV SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the correct dose for you depending upon your age, body weight and disease condition.
Side Effects Of MARILIV SUSPENSION
Common
- feeling sick
- upset stomach
- diarrhoea
- headache
Uncommon
- anaphylaxis (a sudden, severe allergic reaction with swelling and breathing difficulties)
- mild allergic reactions such as itching and/or skin rash, urticaria, hives, pruritus
Rare
Stop taking MARILIV SUSPENSION and contact your doctor immediately if you experience any of the following side effects:
- allergic reactions such as skin rash, red, itchy skin, difficulty breathing, swelling of the facial area, neck, tongue, or throat (anaphylactic shock)
How To Manage Side Effects
Diarrhoea:
Drink lots of fluids and water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhoea and consult your doctor if the symptom gets worse.
Stomach upset:
Try to eat small and frequent meals. Increase the fluid intake. You can also use homemade ginger or other lozenges to increase the palatability of your food.
Nausea:
Try to relax and rest. Eat and drink slowly or try to have smaller and frequent meals. If symptoms do not improve, contact your doctor.
Headache:
Rest and drink plenty of fluids. Ask your doctor to recommend a painkiller. Consult your doctor for advice.
Warning & Precautions
Pregnancy
There are no adequate and well-controlled studies of MARILIV SUSPENSION in pregnant women. Consult your doctor for advice.
Breastfeeding
There are no adequate and well-controlled studies of MARILIV SUSPENSION in lactating women. Consult your doctor for advice.
Driving and Using Machines
MARILIV SUSPENSION is not known to have any effect on driving or operating machines.
Alcohol
Alcohol is contraindicated during the management with MARILIV SUSPENSION.
Liver
MARILIV SUSPENSION should be used with caution in patients with history of hepatic encephalopathy. Consult your doctor before taking MARILIV SUSPENSION.
Allergy
Do not take MARILIV SUSPENSION if you are allergic to Silymarin or any other ingredients of this medicine.
Others
Before taking MARILIV SUSPENSION, inform your doctor if you:
- have any systemic diseases
Use in pediatrics:
MARILIV SUSPENSION is not recommended in children below 5 years of age. Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before taking.
Use in geriatrics:
MARILIV SUSPENSION should be used with caution in elderly (above 65 years of age). Consult your doctor for advice.
Interactions
A. Drug-Drug interactions:
Before taking MARILIV SUSPENSION, inform your doctor if you are taking any of the following medicine:
- amiodarone (used to manage heart problems)
Overdosage:
If you or anyone else accidentally takes too much of MARILIV SUSPENSION, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Silymarin |
| Pharmacological Category | : | Hepatoprotection, Antioxidant, Flavonoids |
| Therapeutic Indication | : | Liver disease, Cirrhosis |
| Dosage Forms | : | Tablet, Capsule, Syrup |
More Information
- Keep MARILIV SUSPENSION out of reach of children
- Store at room temperature
FAQs About MARILIV SUSPENSION
What are the uses of MARILIV SUSPENSION?
It is indicated for supportive management in chronic liver disease and cirrhosis. Silymarin is a flavonoid isolated from the plant species called Silybum marianum which is commonly known as milk thistle.
How to use MARILIV SUSPENSION?
Take MARILIV SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the correct dose for you depending upon your age, body weight and disease condition.
Does MARILIV SUSPENSION has any side effects?
Generally, MARILIV SUSPENSION is well tolerated. However, a few side effects like gastro intestinal discomfort including anorexia, nausea, diarrhoea and headache may be seen. If any of these side effects become worsen, contact your doctor for advice.
Can we use MARILIV SUSPENSION for pregnant women?
There are no adequate and well-controlled studies of MARILIV SUSPENSION in pregnant women. Consult your doctor for advice.
How does MARILIV SUSPENSION work?
MARILIV SUSPENSION contains Silymarin, is an herbal remedy that has been used for centuries for liver diseases. The hepatoprotective and antioxidant activities of silymarin effectively lowers the oxidative liver damage by inhibiting the formation of free radicals. Silymarin also enhances the cellular regeneration of hepatocytes (liver cells) by stimulating the activity of an enzyme called RNA polymerase. It also improves the overall functional capacity of the liver and aids in metabolism and digestion.
References
1. Harsh Mohan. The liver, Biliary tract and Exocrine pancreas. Textbook of Pathology. 6th Edition. Page – 604.
2. Nancy Vargas-Mendoza, Eduardo Madrigal-Santillan, Angel Morales-Gonzalez, Jaime Esquivel-Soto, Cesar Esquivel-Chirino, Manuel García-Luna y González-Rubio, Juan A Gayosso-de-Lucio, and José A Morales-González. Hepatoprotective effect of silymarin. NCBI; PMC US National Library of Medicine, National Institute of Health. [Revised in March 2014] [Accessed in August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959115/#:~:text=Silymarin%20has%20both%20hepatoprotective%20and,hepatocyte%20external%20cell%20membrane%20modification
3. Nitin Dixit1, Sanjula Baboota1, Kanchan Kohli1, S Ahmad2, Javed Ali1. Silymarin A review of pharmacological aspects and bioavailability enhancement approaches. [Accessed on 26th August 2022] https://www.ijp-online.com/article.asp?issn=0253-7613;year=2007;volume=39;issue=4;spage=172;epage=179;aulast=Dixit
4. MIMS. Silymarin. [Accessed on 26th August 2022] https://www.mims.com/philippines/drug/info/silymarin?mtype=generic
5. Abbott Laboratories (Pakistan) Limited, Pharmaceutical. Silymarin. [Accessed on 26th August 2022] https://www.medicine.abbott/content/dam/bss/divisionalsites/epd/pk/Product%20Information/Leaflet%20silliver%20Tabs.pdf
6. Sopharma AD 16 Iliensko Shosse Silymarin. [Revised in Sept 2018] [Accessed in August 2022] https://www.ravimiregister.ee/Data/PIL_ENG/PIL_15708_ENG.pdf
7. ClinicalTrials.gov National Library of Medicine. Silymarin. [Accessed on 26th August 2022] https://clinicaltrials.gov/ct2/show/NCT02006498
8. Silybum Marianum Silybum marianum, improved liver function and antioxidant activity of blood cells. Silymarin. [Accessed on 26th August 2022] https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/silybum-marianum
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