MAGNATE D Suspension 200ml

Introduction About MAGNATE D SUSPENSION

MAGNATE D SUSPENSION is a combination of Dicyclomine, Magaldrate, Oxetacaine and Simethicone which belongs to the group of medicines called Antispasmodics, Antacid, local anaesthetic, and Antiflatulents respectively. It is used to manage muscle spasms of stomach and intestine and reduces bloating, pain, cramps, and discomfort, to counter acidity and for pain relief from stomach ulcers and other acid related injuries.

Avoid alcohol consumption while taking MAGNATE D SUSPENSION as it may cause drowsiness. MAGNATE D SUSPENSION is not recommended in patients with unstable cardiovascular condition with acute haemorrhage, myasthenia gravis, glaucoma, obstructive uropathy, obstructive disease of the gastrointestinal tract, severe ulcerative colitis, reflux esophagitis.

MAGNATE D SUSPENSION should be used with caution in patients with lung disease such as COPD, liver and kidney disease, tachyarrhythmia, hypertension, coronary heart disease, mitral stenosis, congestive heart failure and in cardiac surgery, or mental illness.

Also inform your doctor if you have incomplete intestinal obstruction, salmonella dysentery, ulcerative colitis (inflammatory bowel disease), prostatic hypertrophy (prostate gland enlargement), low magnesium level, alzheimer's dementia, severe constipation or diarrhoea, stomach ulcer or intestinal bleeding.

MAGNATE D SUSPENSION should be used in pregnancy only if clearly needed. MAGNATE D SUSPENSION is not recommended in breastfeeding women, as it may pass through the breast milk. MAGNATE D SUSPENSION is not recommended for use in infants less than 6 months of age. MAGNATE D SUSPENSION should be used with caution in elderly patients. The most common side effects of taking MAGNATE D SUSPENSION are dizziness, dry mouth, vision blurred, nausea, or stomach pain. Consult your physician if any of the side effects worsen.

Uses Of MAGNATE D SUSPENSION

• To manage muscle spasms of stomach and intestine and reduces bloating, pain, cramps, and discomfort, to counter acidity
• For pain relief from stomach ulcers and other acid related injuries

How MAGNATE D SUSPENSION Works

MAGNATE D SUSPENSION is used to manage gastrointestinal muscle spasms where Dicyclomine is an Antispasmodic that works by relaxing the muscles in your stomach and gut (intestine). It manages unexpected muscular contractions (spasms). Thus, reduces bloating, pain, cramps, and discomfort. Magaldrate is an Antacid, neutralises the excess stomach acid. Oxetacaine is a topical anaesthetic that promotes quicker pain relief for stomach ulcers or other acid-related injuries. Simethicone is an antifoaming medication that breaks down gas bubbles and promotes simple gas passage.

How to use MAGNATE D SUSPENSION

Take MAGNATE D SUSPENSION as advised by your physician. Shake well before use. Depending on your age, body weight, disease condition, your doctor will fix the correct dose and duration for you.

Side Effects Of MAGNATE D SUSPENSION

How To Manage Side Effects

Constipation

Consume a lot of foods high in fibre, such as grains, fresh fruits, and vegetables. Drink water and exercise regularly. Contact your doctor if constipation persists.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating machinery if you feel drowsiness or dizziness. Avoid alcohol consumption as it aggravates dizziness or drowsiness. Contact your doctor if dizziness or drowsiness worsen.

Nausea And Vomiting

Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if the nausea doesn’t improve.

Stomach Pain

Try to rest and relax. Eat small meals but take them frequently. Keep a heat pad on your stomach. Contact your doctor if the stomach pain doesn’t improve.

Warning & Precautions

Pregnancy

Monitoring required

MAGNATE D SUSPENSION should be used in pregnancy only if clearly needed. Contact your doctor before taking MAGNATE D SUSPENSION.

Breastfeeding

Contraindicated

MAGNATE D SUSPENSION is not recommended for use in breastfeeding women, as it may pass through the breast milk. Contact your doctor before taking MAGNATE D SUSPENSION.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel drowsiness, dizziness or have blurred vision after taking MAGNATE D SUSPENSION.

Alcohol

Consult your doctor

Avoid alcohol consumption while taking MAGNATE D SUSPENSION as it may cause drowsiness.

Kidney

Use with Caution

MAGNATE D SUSPENSION should be used with caution in patients with kidney disease. Contact your doctor before taking MAGNATE D SUSPENSION.

Liver

Use with Caution

MAGNATE D SUSPENSION should be used with caution in patients with liver disease. Contact your doctor before taking MAGNATE D SUSPENSION.

Allergy

Contraindicated

Do not take MAGNATE D SUSPENSION if you are allergic to Dicyclomine, Magaldrate, Oxetacaine and Simethicone or to other ingredients of this medicine.

Lungs

Use with Caution

MAGNATE D SUSPENSION should be used with caution in patients with Chronic Obstructive Pulmonary Disease. Contact your doctor before taking MAGNATE D SUSPENSION.

Heart Disease

Consult your doctor

MAGNATE D SUSPENSION is not recommended in patients with unstable cardiovascular condition in acute haemorrhage.

MAGNATE D SUSPENSION should be used with caution in tachyarrhythmia, hypertension, coronary heart disease, mitral stenosis, congestive heart failure and in cardiac surgery. Contact your doctor before taking MAGNATE D SUSPENSION.

Use In Pediatrics

Contraindicated

MAGNATE D SUSPENSION is not recommended for use in infants less than 6 months of age. Contact your doctor before taking MAGNATE D SUSPENSION.

Use In Geriatrics

Use with Caution

MAGNATE D SUSPENSION should be used with caution in elderly patients aged above 65 years of age due to increased risk of side effects. Contact your doctor before taking MAGNATE D SUSPENSION.

Interactions

A. Drug - Drug interactions:

Before taking MAGNATE D SUSPENSION inform your doctor if you are taking any of the following medicines:

• antibiotics Ex. such as demeclocycline, doxycycline, minocycline, or tetracycline and ciprofloxacin, ofloxacin, norfloxacin, levofloxacin, lomefloxacin, and methenamine (medicines for bacterial infection)
• tacrolimus (medicines used to manage skin diseases)
• ketoconazole (medicines used for fungal infections)
• ethambutol, isoniazid (medicine used for tuberculosis)
• digoxin (medicine used for heart failure)
• antiglaucoma agents (medicine used to manage glaucoma)
• antacids (medicine used to manage acidity, indigestion)
• corticosteroids Ex. prednisone (medicine used to manage inflammatory conditions)
• bronchodilators (medicine used to manage asthma)
• medicines used to manage overactive bladder Ex. Tolterodine
• amantadine (medicine used to manage parkinson's disease)
• antiarrhythmic agents Ex. quinidine (medicine used to manage irregular heartbeat)
• antihistamines Ex. diphenhydramine (medicine used to manage allergies)
• antipsychotic agents Ex. phenothiazines (medicine used to manage psychoses)
• benzodiazepines (medicines used to manage insomnia, anxiety, fits)
• isocarboxazid, imipramine, desipramine, trazadone (medicine used to manage depression)
• narcotic analgesics Ex. meperidine (medicine used to manage severe pain)
• nitrates (medicines used to manage chest pain)
• nitrites (medicines used as preservatives)
• sympathomimetic drugs (medicines used to manage glaucoma, shock, COPD)
• metoclopramide (used to manage nausea and vomiting)
• pramlintide (used to manage diabetes)
• donepezil, galantamine, tacrine (used to manage Alzheimer’s disease)
• ursodiol (medicine used to manage dissolve gallstones)
• mecamylamine (medicine used to manage high blood pressure)
• sodium polystyrene sulfonate (medicine used to manage hyperkalemia – high level of potassium in blood)
• vitamin or mineral supplements that contain aluminium, calcium, or iron
• alendronate, etidronate, ibandronate, risedronate, or tiludronate (medicine used to manage paget's disease or osteoporosis)
• phosphate-containing medications, including potassium phosphate, sodium acid phosphate, and others
• levothyroxine or liothyronine, liotrix, thyroid desiccated (medicines used to manage hypothyroidism)

Overdosage:

If you or anyone else accidentally takes too much of MAGNATE D SUSPENSION, consult your doctor immediately or visit the nearby hospital. Signs and symptoms of overdose may include headache, nausea, vomiting, blurred vision, dilated pupils, hot, dry skin, dizziness, weakness or loss of movement in any part of your body, fainting dryness of the mouth, difficulty in swallowing, and CNS stimulation including convulsion, muscular weakness and possible paralysis.

Synopsis

More Information

• Keep MAGNATE D SUSPENSION out of reach of children
• Store MAGNATE D SUSPENSION below 25°C

FAQs About MAGNATE D SUSPENSION

Q: MAGNATE D SUSPENSION is used for?

A: MAGNATE D SUSPENSION is used to manage muscle spasms of stomach and intestine and reduces bloating, pain, cramps, and discomfort, to counter acidity and for pain relief from stomach ulcers and other acid related injuries. Consult your doctor before taking MAGNATE D SUSPENSION.

Q: What are the side effects of taking MAGNATE D SUSPENSION?

A: The most common side effects of taking MAGNATE D SUSPENSION are dizziness, dry mouth, vision blurred, nausea, stomach pain, somnolence, asthenia and nervousness, constipation, fever, agitation, dry skin, faecal impaction, chalky taste. Consult your physician if any of the side effects worsen.

Q: Does MAGNATE D SUSPENSION cause dizziness?

A: Yes, MAGNATE D SUSPENSION may cause dizziness. Avoid alcohol consumption as it worsens dizziness and do not drive or operate any machines if you feel dizziness after taking MAGNATE D SUSPENSION.

Q: Who should not use MAGNATE D SUSPENSION?

A: MAGNATE D SUSPENSION is not recommended for use in patients with unstable cardiovascular condition, in acute haemorrhage, myasthenia gravis, glaucoma, obstructive uropathy, obstructive disease of the gastrointestinal tract, severe ulcerative colitis, reflux esophagitis, paralytic ileus, intestinal atony, toxic megacolon, or allergic history to dicyclomine, magaldrate, oxetacaine and simethicone and in infants less than 6 months of age.

Q: What does MAGNATE D SUSPENSION do to the body?

A: MAGNATE D SUSPENSION is used to manage gastrointestinal muscle spasms where Dicyclomine is an Antispasmodic that works by relaxing the muscles in your stomach and gut (intestine). It manages unexpected muscular contractions (spasms). Thus, reduces bloating, pain, cramps, and discomfort. Magaldrate is an Antacid, neutralises the excess stomach acid. Oxetacaine is a topical anaesthetic that promotes quicker pain relief for stomach ulcers or other acid-related injuries. Simethicone is an antifoaming medication that breaks down gas bubbles and promotes simple gas passage.

References

1. KD. Tripathi. Drugs acting on ANS, Gastrointestinal drugs, Local Anaesthetics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 117, 655, 670, 367.

2. Bethesda (MD). Dicyclomine. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 08 September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Dicyclomine

3. Bethesda (MD). Magaldrate. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 08 September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Magaldrate

4. Bethesda (MD). Oxethazaine. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 08 September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Oxethazaine

5. Bethesda (MD). Simethicone. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 08 September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Simethicone

6. Par Pharmaceutical, Inc. Dicyclomine Hydrochloride. [Revised in June 2017] [Accessed on 08 September 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bb099db9-f635-4a64-8892-6236971dec45##

7. Dicyclomine, magaldrate, oxetacaine and simethicone. Trumac Healthcare. [Accessed on 08 September 2022] https://www.trumachealthcare.net/dicyclomine-magaldrate-oxetacaine-oxethazaine-activated-dimethicone-simethicone-suspension-manufacturers-suppliers-in-india-whogmp-third-party-contract-manufacturing/

8. Dicyclomine Syrup and Oral Solution. Drugs.com [Revised in September 2022] [Accessed on 08 September 2022] https://www.drugs.com/cdi/dicyclomine-syrup-and-oral-solution.html

9. Dicyclomine hydrochloride. Drugs.com [Revised in April 2021] [Accessed on 08 September 2022] https://www.drugs.com/pro/dicyclomine.html

10. Magaldrate. Drugs.com [Accessed on 08 September 2022] https://www.drugs.com/mtm/magaldrate.html

11. Simethicone. Drugs.com [Revised in October 2022] [Accessed on 08 September 2022] https://www.drugs.com/mtm/simethicone.html

12. Dicyclomine. RxList.com [Revised in August 2021] [Accessed on 08 September 2022] https://www.rxlist.com/consumer_dicyclomine_bentyl/drugs-condition.htm

13. Magaldrate. RxList.com [Revised in August 2021] [Accessed on 08 September 2022] https://www.rxlist.com/consumer_riopan_magaldrate/drugs-condition.htm

Author Details

Written By Dr. Shruthi M R - BDS

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 13 Feb 2023 | 05:23 PM(IST)