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Introduction About LUPOXA CAPSULE
LUPOXA CAPSULE contains Oxaceprol which belongs to the group of medicines called Anti-inflammatory agents. It is used to manage pain associated with osteoarthritis and rheumatoid arthritis in adult patients.
Osteoarthritis is most common form of arthritis affecting weight bearing joints like hand, knees, hip and spine causing joint pain, stiffness, decreased range of motion, tenderness and swelling.
Rheumatoid arthritis is an autoimmune and chronic progressive inflammatory disease affecting hands, wrist, knees and feet characterised by joint pain, stiffness, tenderness in joints, weight loss, fever, fatigue and weakness.
LUPOXA CAPSULE is not recommended for use in patients with liver or kidney impairment. Contact your doctor before taking it.
LUPOXA CAPSULE is not recommended for use in pregnant women unless it is considered necessary. It is also not recommended for use in breastfeeding women. Contact your doctor before taking it.
LUPOXA CAPSULE is not recommended for use in infants less than 2months of age. The most common side effects of taking LUPOXA CAPSULE are headache, skin rash, itchy skin. Contact your physician if any of the symptoms worsen.
Uses Of LUPOXA CAPSULE
- Manage pain associated with osteoarthritis and rheumatoid arthritis in adults
How LUPOXA CAPSULE Works
LUPOXA CAPSULE helps to relieve pain and swelling of the joints by managing the entry of white blood cells into the joints and inhibits inflammation.
How to use LUPOXA CAPSULE
Take LUPOXA CAPSULE as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. It should be taken before meals. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of LUPOXA CAPSULE
Common
- headache
- skin rash, itchy skin
Rare
Stop taking LUPOXA CAPSULE and contact your physician immediately if you experience any of the following side effects:
- signs of serious allergic reaction or anaphylaxis such as weakness, light-headedness or dizziness or have difficulty breathing
- abdominal pain, nausea, diarrhoea
How To Manage Side Effects
Headache:
Rest and relax. Drink plenty of fluids such as water or ORS (Oral Rehydrating Solution) and apply a pain-relieving balm on the head if necessary. Contact your doctor if the headache did not improve.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not drink alcohol, as it can aggravate your dizziness. Contact your doctor if your dizziness did not improve.
Itchy skin:
Avoid hot bath because hot water can irritate your skin further. Do not scratch the affected area. Use sunscreen and wear protective clothing while going outside. Use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the itching worsens.
Nausea:
Take the medicine, with or just after a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if nausea did not improve.
Stomach pain:
Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on your stomach. Contact your doctor if the stomach pain worsens.
Diarrhoea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Do not take any medicine on your own for managing diarrhoea. Contact your doctor if your diarrhoea did not improve.
Warning & Precautions
Pregnancy
LUPOXA CAPSULE is generally not recommended for use in pregnant women unless it is considered necessary. Contact your doctor before taking it.
Breastfeeding
LUPOXA CAPSULE is not recommended for use in breastfeeding as it not known whether this medicine passes into breast milk. Contact your doctor before taking it.
Driving and Using Machines
LUPOXA CAPSULE has no effect on the ability to drive or operate machines.
Kidney
LUPOXA CAPSULE is not recommended for use in patients with kidney impairment as safety and efficacy has not been established. Contact your doctor before taking it.
Liver
LUPOXA CAPSULE is not recommended for use in patients with liver impairment as safety and efficacy has not been established. Contact your doctor before taking it.
Allergy
Do not take LUPOXA CAPSULE if you are allergic to oxaceprol or any of the other ingredients of this medicine.
Others
Use in paediatrics:
LUPOXA CAPSULE is not recommended for use in infants less than 2months of age as safety and efficacy has not been established. Contact your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking LUPOXA CAPSULE, inform your doctor if you are taking any of the following medicine:
- vitamin K antagonist Ex. warfarin (medicines used to manage or manage blood clots)
- antihypertensives (medicines used for high blood pressure) Ex. enalapril
- methotrexate (used to manage rheumatoid arthritis, psoriasis)
- lithium (used to manage mania)
Overdosage:
If you or anyone else accidentally take too much of LUPOXA CAPSULE, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Oxaceprol |
| Pharmacological Category | : | Anti-inflammatory agents |
| Therapeutic Indication | : | Osteoarthritis, Rheumatoid arthritis |
| Dosage Forms | : | Tablet, Capsule |
More Information
- Keep LUPOXA CAPSULE out of the sight and reach of children
- Store LUPOXA CAPSULE below 30°C
FAQs About LUPOXA CAPSULE
How long can I use LUPOXA CAPSULE?
Take LUPOXA CAPSULE according to the doctors advise and patients can safely use LUPOXA CAPSULE up to 42 days. Patient must consult the doctor for further management with this medicine.
How does LUPOXA CAPSULE decrease pain?
LUPOXA CAPSULE works by managing the entry of white blood cells into the joints and inhibits inflammation. Thus helps to relieve pain and swelling of the joints in patients with osteoarthritis and rheumatoid arthritis.
Who should not take LUPOXA CAPSULE?
LUPOXA CAPSULE is not recommended for use in patients with allergic history to oxaceprol, liver or kidney impairment, pregnant women (unless clearly necessary) and breastfeeding women, infants under 2 months of age. Contact your doctor before taking it.
What are the side effects of taking LUPOXA CAPSULE?
The most common side effects of taking LUPOXA CAPSULE are headache, skin rash, itchy skin. Contact your physician if any of the side effects bothers you.
For what purpose LUPOXA CAPSULE is used?
LUPOXA CAPSULE contains Oxaceprol which belongs to the group of medicines called Anti-inflammatory agents. It is used to manage pain associated with degenerative joint disease like osteoarthritis and inflammatory connective tissue disorder Ex. rheumatoid arthritis in adult patients. Contact your doctor before taking it.
References
1. Sean C Sweetman. Oxaceprol. Martindale: The Complete Drug Reference. 36th edition. 2009. Page-2359.
2. Barbara G. Wells, Joseph T. Dipiro, Terry L. Schwinghammer, Cecily V. Dipiro. Osteoarthritis & Rheumatoid arthritis. Pharmacotherapy handbook. Seventh edition. 2009. Page-9, 31.
3. Herrmann G, Steeger D, Klasser M, Wirbitzky J, Furst M, Venbrocks R, Rohde H, Jungmichel D, Hildebrandt H D, Parnham M J, Gimbel W, Dirschedl H. Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac. National Institute of Health NLM, National Centre for Biotechnology Information. PubMed.gov. 2000. [Accessed on 27th June 2022] https://pubmed.ncbi.nlm.nih.gov/10791619/
4. Bethesda (MD). Oxaceprol. National Institute of Health NLM, National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 27th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/65784
5. Synokem Pharmaceuticals Ltd. Oxaceprol. [Revised in December 2020] [Accessed on 27th June 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2750.pdf
6. Mims.com. Oxaceprol. [Accessed on 27th June 2022] https://www.mims.com/india/drug/info/oxaceprol?type=full&mtype=generic
7. Oxaceprol-200. Care Formulation Labs. [Accessed on 27th June 2022] https://careformulationlabs.com/product/oxaceprol-200/
Useful Diagnostic Tests
- Serum calcium
- Rheumatoid Factor - Agglutination or Turbidometry
- Rheumatoid Factor IgG & IgM Antibody
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