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Introduction About LUPIRTIN CAPSULE
LUPIRTIN CAPSULE contains Flupirtine which belongs to a group of medicines called Nonopioid, Non-NSAID analgesics. It is used in the management of acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles).
LUPIRTIN CAPSULE is not recommended for use in patients with liver problems. Before taking LUPIRTIN CAPSULE, inform your doctor if you have kidney disease, myasthenia gravis, had or have a history of tinnitus (ringing in the ears) or if you are allergic to Flupirtine. LUPIRTIN CAPSULE is not recommended for use in pregnant and breast-feeding women unless clearly advised by the doctor.
LUPIRTIN CAPSULE is not recommended for use in children and adolescents (below 18 years of age) unless deemed necessary and it should be used with caution in elderly patients, especially in patients with kidney problems. The most common side effects of taking LUPIRTIN CAPSULE are fatigue, dizziness, heartburn, nausea, vomiting, dry mouth, constipation and diarrhea. Consult your doctor if any of the side effects worsen.
Uses Of LUPIRTIN CAPSULE
- Manage acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles)
How LUPIRTIN CAPSULE Works
LUPIRTIN CAPSULE works by managing the transmission of pain signals by blocking neuronal excitability and reducing the calcium influx into the cells that is responsible for the sense of pain and inflammation produced at the site of injury and damage and hence it is useful in providing relief from pain, including that is associated with muscle tension.
How to use LUPIRTIN CAPSULE
Take LUPIRTIN CAPSULE as advised by your physician. Swallow the medicine with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age and body weight.
Side Effects Of LUPIRTIN CAPSULE
Common
- Fatigue
- dizziness
- Heartburn
- Nausea
- vomiting
- Diarrhea
- stomach upset
- bloating and pain
- Constipation
- Sleep problems
- Increased sweating
- Loss of appetite
- dry mouth
- Tremors
- headache
- Restlessness, nervousness
Uncommon
- Confusion
- Vision problems
- Skin rash, hives and itching
Rare
- Elevated levels of liver enzymes in blood
Stop taking LUPIRTIN CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- Signs of hepatic encephalopathy (forgetfulness, confusion, breath with a sweet or musty odor, shaking of the hands or arms, disorientation and slurred speech)
- Signs of drug-induced hepatitis (stomach pain, tiredness, fever, nausea, vomiting, dark urine and pale-colored stools)
How To Manage Side Effects
Constipation
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not improve, consult your doctor.
Diarrhea
Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to manage diarrhea and consult your doctor if the symptom gets worse.
Dry Mouth
Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Headache
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Nausea And Vomiting
Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
Monitoring requiredLUPIRTIN CAPSULE is not recommended during pregnancy unless considered clearly necessary. Consult your doctor before taking LUPIRTIN CAPSULE.
Breastfeeding
Monitoring requiredLUPIRTIN CAPSULE is not recommended in breastfeeding women unless considered clearly necessary. Consult your doctor before taking LUPIRTIN CAPSULE.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy or sleepy after taking LUPIRTIN CAPSULE.
Alcohol
Consult your doctorAvoid consuming alcohol while taking LUPIRTIN CAPSULE as it may increase the risk of liver problems.
Kidney
Use with CautionLUPIRTIN CAPSULE should be used with caution in patients with kidney diseases. Consult your doctor for advice before taking LUPIRTIN CAPSULE.
Liver
ContraindicatedLUPIRTIN CAPSULE is not recommended for use in patients with liver problems. Consult your doctor for advice before taking LUPIRTIN CAPSULE.
Allergy
ContraindicatedLUPIRTIN CAPSULE is not recommended for use if you are allergic to flupirtine.
Use In Pediatrics
ContraindicatedLUPIRTIN CAPSULE is not recommended for use in children and adolescents (below 18 years of age) unless deemed necessary. Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionLUPIRTIN CAPSULE should be used with caution in elderly patients, especially in patients with any kidney problems. Consult your doctor for advice before taking LUPIRTIN CAPSULE.
Others
Before taking LUPIRTIN CAPSULE, inform your doctor if you:
- Have myasthenia gravis
- Had or have a history of tinnitus (ringing in the ears)
Interactions
A. Drug-Drug interactions:
Before taking LUPIRTIN CAPSULE, inform your doctor, if you are taking any of the following medicines:
- Medicines that manage or manages blood clot (Ex. warfarin, dicumarol)
- Paracetamol (used to reduce fever and inflammation)
- Carbamazepine (used to manage epilepsy)
- Diazepam (used to manage anxiety and alcohol withdrawal)
Overdosage:
If you or anyone else accidentally takes too much of LUPIRTIN CAPSULE, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Flupirtine |
| Pharmacological Category | : | Triaminopyridine |
| Therapeutic Indication | : | Pain Relief |
| Dosage Forms | : | Tablet, Capsule |
More Information
Storage
- Keep LUPIRTIN CAPSULE out of reach of children
- Store at room temperature
FAQs About LUPIRTIN CAPSULE
Q: What is LUPIRTIN CAPSULE used for?
A: LUPIRTIN CAPSULE is used in the management of acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles).
Q: What common side effects are seen with LUPIRTIN CAPSULE?
A: The most common side effects of taking [GBNKEYWORD are fatigue, dizziness, heartburn, nausea, vomiting, dry mouth, diarrhoea, constipation, diarrhea, stomach upset, bloating and pain, loss of appetite, tremor, headache, increased sweating, sleep problems and restlessness. Consult your doctor if any of the side effects worsen.
Q: How does LUPIRTIN CAPSULE work?
A: LUPIRTIN CAPSULE works by managing the transmission of pain signals by blocking neuronal excitability and reducing the calcium influx into the cells that is responsible for the sense of pain and inflammation produced at the site of injury and damage, and hence it is useful in providing relief from pain, including that is associated with muscle tension.
Q: Can LUPIRTIN CAPSULE be used in pregnant women?
A: LUPIRTIN CAPSULE is not recommended for use in pregnant women unless clearly advised by the doctor. Consult your doctor before taking LUPIRTIN CAPSULE if you are pregnant or planning to get pregnant.
Q: Is LUPIRTIN CAPSULE safe to use in patients with kidney diseases?
A: LUPIRTIN CAPSULE should be used with caution in patients with kidney diseases. Your doctor may regularly monitor your kidney function before and during management with LUPIRTIN CAPSULE to manage the risk of kidney damage. Consult your doctor for advice before taking LUPIRTIN CAPSULE.
References
1. KD. Tripathi. Opioid Analgesics and Antagonists. Essentials of medical pharmacology. Seventh edition. 2013. Page – 469- 486.
2. Harish S, Bhuvana K, Bengalorkar GM, Kumar T. Flupirtine: Clinical pharmacology. Journal of Anaesthesiology and Clinical Pharmacology. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2012. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339720/
3. Singal R, Gupta P, Jain N, Gupta S. Role of flupirtine in the treatment of pain - chemistry and its effects. Journal of Clinical medicine. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2012. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557425/
4. Kim Lawson. Pharmacology and clinical applications of flupirtine: Current and future options. World Journal of Pharmacology. January 2019. [Accessed on 21st June 2022] https://www.wjgnet.com/2220-3192/full/v8/i1/1.htm
Useful Diagnostic Tests
- Liver function test
- Kidney function test
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