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Introduction About LOX 10% SPRAY
LOX 10% SPRAY contains Lignocaine which belongs to the group of medicines called Local Anaesthetics. It is used to cause numbness (loss of sensation) of body parts at sites where it has been administered in the body. It relieves pain and discomfort in the nose and throat following minor surgical procedures (such as the removal of tonsils or adenoid glands).
It also anesthetizes the nose, throat, respiratory tract (lungs), or digestive tract (stomach) prior to the insertion of catheters or certain diagnostic instruments that are used for viewing parts of the body (such as bronchoscopy or esophagoscopy).
It can be used to numb the oral cavity, manage gag reflux (vomiting sensation) that occurs during dental procedures, and manage painful oral conditions (such as oral injury, infection, or inflammation) by alleviating pain sensation. It may also help in managing pain caused by episiotomy (tearing the skin between the vagina and anus during childbirth).
Following the administration of LOX 10% SPRAY, avoid oral foods or chewing gums for at least 1-2 hours or until sensation comes back. This is because you may experience trouble swallowing or accidentally bite your tongue or cheek muscles during this period. Do not drink water or other fluids after applying LOX 10% SPRAY, as it may reduce its anaesthetic effects.
Before using LOX 10% SPRAY, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have low blood pressure, a severe injury or bleeding in the nose, mouth, or throat, or epilepsy before using LOX 10% SPRAY.
LOX 10% SPRAY should be used in pregnant or breastfeeding women only if it is considered necessary by the physician. It is generally safe and well tolerated without any major side effects. However, if you experience any irritation on the application site or feel drowsy, consult your doctor for advice.
Uses Of LOX 10% SPRAY
It is used to:
- Cause numbness of the mouth, nose, throat, respiratory tract, or digestive tract
- Relieve the pain and discomfort associated with minor surgeries of the nose and throat
- Prevent gag reflux (vomiting sensation) during dental procedures
- Reduce pain caused by episiotomy (a minor surgery done during childbirth)
How LOX 10% SPRAY Works
LOX 10% SPRAY is a local anaesthetic agent. It reduces pain sensation and causes numbness in body parts by blocking the flow of certain ions (sodium ions) through the nerves that cause pain sensation. As a result, it limits the transfer of pain signals from the peripheral part of the body (i.e., the face, hands, legs, abdomen, pelvis, or where the medicine has been applied) to the brain, which ultimately leads to loss of sensation.
How to use LOX 10% SPRAY
LOX 10% SPRAY should be used under proper medical supervision. It is usually administered by the physician prior to the surgical or diagnostic procedures. However, it may also be self-administered by the patient if instructed by the doctor for temporary pain relief.
Shake the container before use. Prior to use, prime the medicine to release the correct dose of medicine. Fix the extension tube if it is given in the package. Hold the container with the extension tube or spray nozzle pointing towards the areas of application. Press the button to release the spray. Leave a time gap of 2 seconds between each spray.
Your doctor will decide the correct dose, number of sprays, and duration of therapy for you depending on your age, body weight, and health condition. Avoid contact with LOX 10% SPRAY with your eyes.
Side Effects Of LOX 10% SPRAY
Common
- skin rash or irritation
- drowsiness
Consult your doctor immediately if you experience any of the following side effects after using LOX 10% SPRAY:
- swelling of your face, lips, tongue, or throat, difficulty swallowing, severe or sudden swelling of your hands, feet and ankles, difficulty or severe itching or rashes of the skin (with raised lumps)
- severe itching sensation of the skin
- difficulty breathing, slow heartbeat
- fits (convulsions)
How To Manage Side Effects
Dizziness Or Drowsiness
Avoid standing or walking while you are feeling dizzy. Try to rest and relax. Get enough sleep. Consult your doctor if you continue to feel dizzy for a prolonged period of time.
Warning & Precautions
Pregnancy
Consult your doctorLOX 10% SPRAY should be used in pregnant women only if it is considered necessary by the physician. Therefore, inform your doctor before using LOX 10% SPRAY if you are pregnant or think you may be pregnant.
Breastfeeding
Consult your doctorLOX 10% SPRAY should be used for breastfeeding women only if it is considered necessary by the physician. Therefore, inform your doctor before using LOX 10% SPRAY if you are breastfeeding.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if your abilities are affected by LOX 10% SPRAY.
Kidney
Use with CautionLOX 10% SPRAY should be used with caution in patients with kidney problems. Therefore, inform your doctor before using it.
Liver
Use with CautionLOX 10% SPRAY should be used with caution in patients with liver problems. Therefore, inform your doctor before using it.
Allergy
Consult your doctorInform your doctor before using LOX 10% SPRAY if you are allergic to lignocaine or to other local anaesthetics (such as bupivacaine or prilocaine).
Heart Disease
Use with CautionLOX 10% SPRAY should be used with caution in patients with heart diseases (such as a slow heartbeat or very low blood pressure). Therefore, inform your doctor before using it.
Use In Pediatrics
Consult your doctorLOX 10% SPRAY can be used in children and adolescents (aged between 3 and 18 years). It should be used in children aged below 3 years only if prescribed by the physician. Your doctor will prescribe a suitable dose for your child based on their age, body weight, health condition, and capacity for spitting and swallowing. It is generally not used to soothe teething pain in infants. However, consult your doctor for advice.
Use In Geriatrics
Use with CautionLOX 10% SPRAY should be used with caution with elderly patients. Your doctor will prescribe the appropriate dose for you based on your age, body weight, and sites where numbness is required in the body.
Others
Before using LOX 10% SPRAY, inform your physician if you have:
- a severe injury or bleeding in the nose, mouth, or throat
- epilepsy (fits)
- or have a family history of porphyria (an inherited blood disorder)
- an infection in the chest
Interactions
A. Drug-Drug interactions:
Before using LOX 10% SPRAY, inform your doctor if you are taking any of the following medicines, such as:
- mexiletine (a medicine used to manage an uneven heartbeat)
Overdosage:
If you accidentally ingested more LOX 10% SPRAY, contact your doctor immediately or visit a nearby hospital immediately. If exposed to the eyes, wash your eye with cold water or consult your doctor for advice.
Synopsis
| Drug | : | Lignocaine |
| Pharmacological Category | : | Voltage Gated Sodium Channel Blockers |
| Therapeutic Indication | : | Local anesthesia, Arrythmia |
| Dosage Forms | : | Injection, Gel, Cream, Ointment, Jelly, Topical Solution, Spray, Oral solution, Plaster |
More Information
- Keep LOX 10% SPRAY out of reach of children
- Store LOX 10% SPRAY at room temperature
FAQs About LOX 10% SPRAY
Q: How long will it take for LOX 10% SPRAY to induce numbness?
A: It may take around 5 minutes for LOX 10% SPRAY to create numbness. However, this period may vary from person-to-person based on the dose and amount of LOX 10% SPRAY that is administered to you.
Q: How long do the effects of LOX 10% SPRAY last in the body?
A: The effects of LOX 10% SPRAY may last from 20–30 minutes up to 1 hour after application. However, the recovery period may vary from person-to-person based on the dose and amount of the LOX 10% SPRAY applied.
Q: What is the use of LOX 10% SPRAY?
A: LOX 10% SPRAY is used to cause numbness of the oral cavity, respiratory tract, and digestive tract, which may be helpful in reducing pain, inflammation, or discomfort of the mouth, throat, or esophagus, reducing gagging during dental procedures, and causing loss of sensation in patients prior to the insertion of a catheter or instruments meant for diagnostic procedures (such as bronchoscopy or esophagoscopy). It may also help in reducing pain caused by an episiotomy.
Q: How do I use LOX 10% SPRAY?
A: LOX 10% SPRAY should be used under proper medical supervision. It is usually administered by the physician prior to the surgical or diagnostic procedures. However, it may also be self-administered by the patient if instructed by the doctor for temporary pain relief. Shake the container before use. Prior to use, prime the medicine to release the correct dose of medicine. Fix the extension tube if it is given in the package. Hold the container with the extension tube or spray nozzle pointing towards the areas of application. Press the button to release the spray. Leave a time gap of 2 seconds between each spray.
Q: Can LOX 10% SPRAY be used with children?
A: Yes. LOX 10% SPRAY can be used in children and adolescents (aged between 3 and 18 years). It should be used in children aged below 3 years only if prescribed by the physician.
Q: Can you drink water after consuming LOX 10% SPRAY?
A: Avoid eating foods or drinking water or other fluids after applying LOX 10% SPRAY, as it may reduce its anaesthetic effects.
Q: How often can we use LOX 10% SPRAY?
A: LOX 10% SPRAY should be used as instructed by the doctor. Your doctor will decide the duration of therapy for you depending upon your age, body weight, health condition, and sites where numbness is required in the body.
Q: Can LOX 10% SPRAY be used in infants?
A: LOX 10% SPRAY should be used in children aged below 3 years only if prescribed by the physician. Therefore, consult your doctor for advice before use.
Q: Will LOX 10% SPRAY cause sleepiness?
A: LOX 10% SPRAY may cause sleepiness when used more than the recommended dosage. It may also happen if you apply this medicine more frequently over a shorter period of time. In such cases, consult your doctor for advice.
Q: Can LOX 10% SPRAY be used to reduce gagging?
A: LOX 10% SPRAY is used to manage gagging sensations during dental procedures.
Q: What if I accidentally exposed LOX 10% SPRAY to the eye?
A: Use lukewarm water to gently wash the outer surface of the eye in case of accidental contact with LOX 10% SPRAY. If the discomfort in the eye persists, contact your doctor or visit a nearby hospital immediately.
References
1. KD. Tripathi. Drugs acting on peripheral (somatic) nervous system. Essentials of medical pharmacology. 8th Edition. 2019. Page – 392.
2. Somchai Amornyotin, W Srikureja, W Chalayonnavin and Siriporn Kongphlay. Topical viscous lidocaine solution versus lidocaine spray for pharyngeal anesthesia in unsedated esophagogastroduodenoscopy. Thieme. Endoscopy. 2009. [Accessed on 10th September 2022] https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0029-1214865
3. AstraZeneca UK Ltd. Electronic Medicines Compendium (EMC). [Revised on March 2021] [Accessed on 10th September 2022] https://www.medicines.org.uk/emc/files/pil.882.pdf
4. AstraZeneca Pty Ltd. Xylocaine 10% Pump Spray. Lidocaine (lignocaine). NPS. Medicine wise. [Revised in March 2009]. [Accessed on 10th September 2022] https://www.nps.org.au/assets/medicines/2980262e-a940-413e-afd3-a53300feed99.pdf
5. Inibsa Dental. XILONIBSA SPRAY 10%. [Accessed on 10th September 2022] http://inibsadental.com/wp-content/uploads/2015/09/Prospecto-Xilonibsa-Spray-EN.pdf
6. IPCA Laboratories Ltd. Nummit Spray. Surface Anesthetic Spray. [Accessed on 10th September 2022] https://www.icpahealth.com/product/nummit-spray/
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