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Introduction About LOTEPRED T EYE DROPS
LOTEPRED T EYE DROPS is a combination of Loteprednol Etabonate and Tobramycin which belongs to the group of medicines called Corticosteroids and Antibiotics. It is used to manage inflammatory eye conditions along with superficial bacterial eye infections such as palpebral conjunctiva (the lining of your eyelids) and bulbar conjunctiva (the covering over the eyeball that protects the white of the eye), allergic conjunctivitis (eye inflammation caused by allergies).
LOTEPRED T EYE DROPS is also used to manage acne rosacea (flushing of the face), superficial punctate keratitis (an eye disorder), herpes zoster keratitis (viral infection of eye), iritis (inflammation of coloured part of the eye), cyclitis (inflammation of the muscles that operate the lens of eyes), chronic anterior uveitis (inflammation of front part of the eye) and eye injury from chemical, radiation or thermal burns or penetration of foreign bodies.
LOTEPRED T EYE DROPS is not recommended for use if you have epithelial herpes simplex keratitis (viral infection of the eye), vaccinia (smallpox) and varicella (chicken pox) or fungal diseases of the eye. Consult your doctor before using it.
LOTEPRED T EYE DROPS should be used with caution in patients with kidney disease, glaucoma (increased eye pressure), cataracts (cloudy eyes). Consult your doctor before using it.
LOTEPRED T EYE DROPS is generally not recommended for use in pregnancy unless considered clearly necessary. It should be used with caution in breastfeeding women. Consult your doctor before using it.
LOTEPRED T EYE DROPS is not recommended for use in children. It should be used with caution in elderly patients. The most common side effects of using LOTEPRED T EYE DROPS are burning and stinging sensation upon instillation. Consult your doctor if any of the symptoms worsen.
Uses Of LOTEPRED T EYE DROPS
Manages inflammatory eye conditions along with superficial bacterial eye infection such as:
- palpebral and bulbar conjunctiva
- allergic conjunctivitis
- acne rosacea
- superficial punctate keratitis
- herpes zoster keratitis
- iritis
- cyclitis
- chronic anterior uveitis
- eye injury
How LOTEPRED T EYE DROPS Works
LOTEPRED T EYE DROPS is a combination of Loteprednol and Tobramycin where Loteprednol Etabonate is a Corticosteroid that helps to reduce swelling and inflammation and Tobramycin works by killing the bacteria or managing it from growing. Together helps to manage inflammatory eye conditions along with bacterial infection.
How to use LOTEPRED T EYE DROPS
Use LOTEPRED T EYE DROPS as advised by your doctor. It is for ophthalmic use only. Shake well before use. Tilt your head backward, hold the bottle upside down above the eye and dispense drops with gentle pressure. Do not touch tip of container to any surface to avoid contamination.
Side Effects Of LOTEPRED T EYE DROPS
Common
- superficial punctate keratitis (damage to the cells of eye's outer layer)
- burning and stinging upon instillation
Rare
Stop applying LOTEPRED T EYE DROPS and contact your physician immediately if you experience any of the following side effects:
- allergic reactions
- increased or persistent irritation
Warning & Precautions
Pregnancy
Monitoring requiredLOTEPRED T EYE DROPS is generally not recommended for use in pregnancy unless considered clearly necessary. Consult your doctor before using it.
Breastfeeding
Use with CautionLOTEPRED T EYE DROPS should be used with caution in breastfeeding women. Consult your doctor before using it.
Kidney
Use with CautionLOTEPRED T EYE DROPS should be use with caution in patients with kidney disease. Consult your doctor before using it.
Use In Pediatrics
ContraindicatedLOTEPRED T EYE DROPS is not recommended for use in children as safety and efficacy have not been established. Consult your doctor before using it.
Use In Geriatrics
Use with CautionLOTEPRED T EYE DROPS should be used with caution in elderly patients. Consult your doctor before using it.
Others
LOTEPRED T EYE DROPS is not recommended for use if you:
- have epithelial herpes simplex keratitis or dendritic keratitis (viral infection of the eye)
- have vaccinia (smallpox) and varicella (chicken pox)
- have mycobacterial or fungal diseases of the eye
Before using LOTEPRED T EYE DROPS, inform your doctor if you:
- have glaucoma (increased eye pressure)
- have cataracts (cloudy eyes) or are scheduled for cataract surgery
- have bacterial eye infections
Interactions
A. Drug-Drug interactions:
Before using LOTEPRED T EYE DROPS, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicine.
Overdosage:
If you or anyone else accidentally put too much of LOTEPRED T EYE DROPS or if there is the accidental ingestion, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Loteprednol Etabonate, Tobramycin. |
| Pharmacological Category | : | Corticosteroids, Aminoglycosides |
| Therapeutic Indication | : | Palpebral and bulbar conjunctivitis, allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes, zoster keratitis, iritis, cyclitis, chronic anterior uveitis, eye injury |
| Dosage Forms | : | Eye injury |
More Information
- Keep LOTEPRED T EYE DROPS out of the sight and reach of children
- Store LOTEPRED T EYE DROPS below 25°C
FAQs About LOTEPRED T EYE DROPS
Q: How often can I use LOTEPRED T EYE DROPS?
A: Apply LOTEPRED T EYE DROPS as advised by your physician. It is for ophthalmic use only. Apply one or two drops of LOTEPRED T EYE DROPS into the affected eye every four to six hours. Consult your doctor before using it.
Q: Does LOTEPRED T EYE DROPS cause glaucoma?
A: Apply LOTEPRED T EYE DROPS as advised by your physician. Prolonged use of corticosteroids may result in glaucoma (Increased eye pressure) with damage to the optic nerve and also cause a decrease in clarity or sharpness of vision. Your doctor will monitor your eye pressure If this medicine is used for 10 days or longer.
Q: Can I wear a contact lens while using LOTEPRED T EYE DROPS?
A: Avoid wearing contact lenses if you use this medicine and you should remove contact lenses before using this medicine and put them back 15 minutes after use. Consult your doctor for advice before using it.
Q: Are there any specific instructions I need to follow while using LOTEPRED T EYE DROPS?
A: LOTEPRED T EYE DROPS should be used only in the eyes. Be careful and do not touch the tip of the bottle to your eye or any other surface to avoid contamination. Consult your physician if pain develops, redness, itching or inflammation becomes aggravated.
Q: Is LOTEPRED T EYE DROPS safe to use in pregnant women?
A: LOTEPRED T EYE DROPS is generally not recommended for use in pregnancy unless considered clearly necessary. Inform our doctor if you are pregnant or planning to become pregnant before using this medicine.
References
1. Laurence L. Brunton, John S. Lazo, Keith L. Parker. Ophthalmology, Chemotherapy of Microbial Diseases. Goodman & Gilman's The Pharmacological Basis of Therapeutics. Eleventh Edition. 2006. Page – 1724, 1166.
2. Gizem Reyhanoglu, Anil Kumar Reddy Reddivari. Tobramycin. NIH National Library of Medicine, National Center for Biotechnology Information. StatPearls. February 2022. [Accessed on 31st May 2022] https://www.ncbi.nlm.nih.gov/books/NBK551695/
3. Bausch & Lomb Incorporated. Loteprednol and Tobramycin Versus Tobramycin and Dexamethasone, in the Treatment of Blepharokeratoconjunctivitis. NIH U.S. National Library of Medicine ClinicalTrials.gov. February 2012. [Accessed on 31st May 2022] https://clinicaltrials.gov/ct2/show/NCT01028027
4. Nebracin LP (Loteprednol Etabonate + Tobramycin Eye drops). Sunways India Pvt. Ltd. [Accessed on 31st May 2022] http://www.sunways.com/Products/SunwaysProducts/Nebracin-LP.html
5. Loteprednol Etabonate + Tobramycin Eye drops. Daily Med: National Library of Medicine: National Institute of Health. [Revised in April 2022]. [Accessed on 31st May 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3dd9b060-5355-404d-bdf1-09ee8b52a9f5
Useful Diagnostic Tests
- slit lamp biomicroscopy
- fluorescein staining
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