Lomela Cream 18Gm

Introduction About LOMELA CREAM

Lomela Cream contains hydroquinone (a skin-lightening agent), mometasone furoate (a topical corticosteroid), and tretinoin (a vitamin A derivative). It is prescribed for the short-term management of melasma (dark patches on the skin) and certain forms of hyperpigmentation, where reducing excess pigmentation, controlling inflammation, and promoting skin cell turnover are beneficial. Hydroquinone helps reduce the production of melanin, mometasone helps reduce redness and inflammation, and tretinoin promotes the shedding of pigmented skin cells and enhances the penetration of hydroquinone. This cream should only be used for the condition and duration prescribed by your doctor and should not be used for prolonged periods or on unaffected skin without medical advice.

Use Lomela Cream exactly as prescribed by your doctor. Clean and dry the affected area before application. Apply a thin layer only to the affected skin, preferably at night, and gently rub it in until absorbed. Wash your hands before and after applying the cream unless your hands are the area being treated. Avoid contact with the eyes, lips, inside the nose, and other mucous membranes. Do not apply it to broken, irritated, sunburned, or infected skin. Avoid covering the treated area with airtight dressings unless advised by your doctor. During treatment, use a broad-spectrum sunscreen and protective clothing, as tretinoin and hydroquinone may increase sensitivity to sunlight. Continue using the cream for the prescribed duration and do not stop or extend treatment without medical advice.

Do not use Lomela Cream if you are allergic to hydroquinone, mometasone, tretinoin, or any of its ingredients. Before starting treatment, inform your doctor if you have eczema, rosacea, psoriasis, thinning of the skin, liver disease, diabetes, or any active skin infection. Also tell your doctor if you have a history of sensitivity to sunlight or are using other topical medicines, corticosteroid creams, exfoliating agents, benzoyl peroxide, salicylic acid, or medicated skin preparations on the same area, as these may increase skin irritation.

Common side effects of Lomela Cream may include mild burning, stinging, redness, dryness, peeling, itching, irritation, or a temporary sensation of warmth at the application site. Increased sensitivity to sunlight may also occur. Prolonged or excessive use may increase the risk of skin thinning, stretch marks, acne-like eruptions, changes in skin colour, visible blood vessels, or, rarely, ochronosis (bluish-black skin discoloration associated with long-term hydroquinone use). Seek immediate medical attention if you develop severe skin irritation, blistering, swelling of the face, lips, tongue, or throat, difficulty breathing, or signs of a severe allergic reaction. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using this cream. Children and older adults should use this medicine only under medical supervision, as they may be more susceptible to corticosteroid-related side effects.

Uses Of LOMELA CREAM

• Manages moderate to severe melasma (dark spots on the skin)

Benefits of LOMELA CREAM

Lomela Cream 18gm for for Melasma

Lomela Cream 18gm for is commonly prescribed for the short-term management of melasma (dark patches on the skin), particularly on the face. It contains hydroquinone, which helps reduce excess melanin production, tretinoin, which promotes skin cell turnover, and mometasone, which helps reduce redness and irritation associated with treatment. Use this cream only for the prescribed duration under medical supervision.

Lomela Cream 18gm for for Hyperpigmentation

Lomela Cream 18gm for may be prescribed for certain types of hyperpigmentation, including dark spots caused by sun exposure or post-inflammatory skin changes. Hydroquinone helps lighten areas of excess pigmentation, tretinoin enhances skin renewal, and mometasone helps reduce inflammation and irritation. It should only be used as directed by a healthcare professional.

Lomela Cream 18gm for for Uneven Skin Tone

Lomela Cream 18gm for is used under medical supervision to help improve uneven skin tone associated with melasma and certain pigmentary disorders. The combination of hydroquinone, mometasone, and tretinoin helps reduce excess pigmentation while relieving irritation and promoting healthy skin renewal. Apply the cream exactly as directed by your doctor and avoid prolonged or unnecessary use.

How LOMELA CREAM Works

How Lomela Cream 18gm works

Lomela Cream 18gm contains hydroquinone, mometasone furoate, and tretinoin, which work together to help improve melasma and certain hyperpigmented skin conditions. Hydroquinone helps reduce the production of melanin, the pigment responsible for skin darkening. Tretinoin is a retinoid that promotes skin cell turnover, helping fade pigmented skin cells and improve the effectiveness of hydroquinone. Mometasone is a corticosteroid that helps reduce inflammation, redness, itching, and irritation associated with the condition and treatment.

How to use LOMELA CREAM

How to Use Lomela Cream 18gm

• Wash and dry the affected area, then apply a thin layer of as prescribed Lomela Cream 18gm by your doctor.
• Gently rub the cream into the skin until absorbed and wash your hands before and after application (unless treating your hands).
• Avoid contact with the eyes, mouth, lips, nose, and other mucous membranes. Do not apply the cream to broken or infected skin unless advised by your doctor.
• Apply the cream regularly, preferably at night, for the full prescribed duration. Use sunscreen during the day and avoid excessive sun exposure while using this medicine.
• Do not use more than the recommended amount or continue treatment longer than prescribed without medical advice.

What if I forgot to take LOMELA CREAM

• If you forget to apply Lomela Cream 18gm, apply it as soon as you remember.
• If it is almost time for your next scheduled application, skip the missed dose and continue with your regular application schedule.
• Do not apply extra cream or use it more frequently to make up for the missed application.
• Missing applications repeatedly may reduce the effectiveness of the medicine in managing your skin condition.
• If you frequently forget to apply the cream, try setting a reminder or apply it at the same time each day as advised by your doctor.

Overdose

If you or anyone else accidentally swallows or applies more Lomela Cream than prescribed, seek medical advice or contact your doctor immediately.

Side Effects Of LOMELA CREAM

Common side effects of Lomela Cream 18Gm

• Mild burning
• Stinging
• Redness
• Dryness

When to Seek Medical Attention?

Stop using Lomela Cream 18Gm and inform your doctor immediately if you experience any of the following

• Infraorbital and paranasal fissures

How To Manage Side Effects

Application Site Reactions

• Apply a cool compress: Place a clean, cool, damp cloth on the affected area for 10–15 minutes to help soothe the burning sensation. Avoid using ice directly on the skin.
• Use a gentle moisturizer: Apply a fragrance-free, non-comedogenic moisturizer if recommended by your doctor to reduce dryness and irritation.
• Avoid harsh skincare products: Do not use scrubs, exfoliants, alcohol-based toners, or products containing strong acids on the treated area, as they may worsen the burning.
• Protect your skin from sunlight: Use a broad-spectrum sunscreen (SPF 30 or higher) and wear protective clothing when outdoors, as sun exposure can increase skin irritation.
• Wash with a mild cleanser: Cleanse the affected area with a gentle, soap-free cleanser and lukewarm water. Avoid hot water, which may aggravate the skin.
• Do not scratch or rub the area: Touching or rubbing the treated skin may increase irritation and delay recovery.
• Avoid applying more than prescribed: Using a larger amount or applying the cream more often than directed may increase burning and irritation.
• Take a break from other irritating products: Avoid using other medicated creams, retinoids, or exfoliating products on the same area unless advised by your doctor.

Warning & Precautions

Pregnancy

Consult your doctor

The safety of Lomela Cream during pregnancy has not been fully established. If you are pregnant or planning to become pregnant, consult your doctor before using this cream.

Breastfeeding

Use with Caution

Use with caution Lomela Cream only after consulting your doctor. Your doctor will determine whether it is appropriate for you.

Allergy

Contraindicated

Avoid using Lomela Cream if you are allergic to hydroquinone, tretinoin, mometasone, or any of the other ingredients in this medicine. Seek medical advice before use if you have a history of allergies to these substances.

Use In Pediatrics

Consult your doctor

The safety and effectiveness of Lomela Cream have not been established in children below 12 years of age. Consult your child's doctor before using this medicine.

Use In Geriatrics

Consult your doctor

There is limited information on the use of Lomela Cream in elderly patients. Consult your doctor before using this medicine to ensure it is suitable for you.

Other Warnings for LOMELA CREAM

Before taking Lomela Cream, inform your doctor if you

• Have ever had an allergic reaction to hydroquinone, tretinoin, mometasone, or any other ingredient in this cream.
• Have eczema, sunburn, broken, irritated, or infected skin at the application site.
• Have a history of skin sensitivity or reactions to topical medicines.
• Have recently undergone chemical peels, laser treatments, or other cosmetic skin procedures.
• Are regularly exposed to sunlight or ultraviolet (UV) light, as this medicine may increase skin sensitivity to the sun.
• Are planning to use this cream on a child below 12 years of age. Always consult a doctor before use.

Safety Advice

• Use Only as Prescribed: Apply Lomela Cream exactly as directed by your doctor. Do not apply more than the recommended amount or use it for longer than prescribed.
• For External Use Only: Lomela Cream is meant for application on the skin only. Avoid contact with the eyes, mouth, inside the nose, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
• Apply a Thin Layer: Clean and dry the affected area before application. Apply a thin layer of the cream only to the affected skin and wash your hands after use unless your hands are being treated.
• Protect Your Skin from Sunlight: Lomela Cream may increase your skin's sensitivity to sunlight. Use a broad-spectrum sunscreen, wear protective clothing, and avoid excessive sun exposure or tanning lamps during treatment.

Diet and Lifestyle Advice

• Use sunscreen daily: Apply a broad-spectrum sunscreen (SPF 30 or higher) every morning and reapply as needed, especially when spending time outdoors.
• Limit sun exposure: Avoid prolonged exposure to direct sunlight, tanning beds, and UV lamps, as the cream can make your skin more sensitive to sunlight.
• Wear protective clothing: Use a wide-brimmed hat, sunglasses, and clothing that covers the treated area when outdoors.
• Follow a gentle skincare routine: Use a mild cleanser and a fragrance-free moisturizer to help reduce dryness and skin irritation.
• Avoid harsh skincare products: Do not use products containing alcohol, exfoliating agents, astringents, or other irritating ingredients on the treated area unless advised by your doctor.
• Do not pick or scrub the skin: Avoid rubbing, scratching, or peeling the treated skin, as this may worsen irritation or delay improvement.
• Keep your skin hydrated: Drink adequate water and use a suitable moisturizer if recommended by your doctor to help maintain healthy skin.
• Eat a balanced diet: Include plenty of fruits, vegetables, whole grains, and protein-rich foods to support overall skin health.
• Avoid sharing the cream: Use Lomela Cream only for the person it has been prescribed for and do not share it with others.
• Follow your treatment plan: Apply the cream regularly as prescribed and attend follow-up appointments so your doctor can monitor your progress.

1.Lomela Cream vs Hydroquinone Cream

Drug - Drug interaction

1. Other Skin-Lightening Products (e.g., Hydroquinone, Kojic Acid, Arbutin)

• Interaction: Using multiple skin-lightening products together may increase the risk of skin irritation, redness, dryness, and peeling.
• Management: Use such products only if recommended by your doctor. Avoid combining them without medical advice.

2. Topical Retinoids (e.g., Tretinoin, Adapalene, Tazarotene)

• Interaction: Using additional retinoids with Lomela Cream may increase skin dryness, peeling, burning, and irritation.
• Management: Inform your doctor if you are already using a retinoid. Your treatment schedule may need to be adjusted.

3. Corticosteroid Creams or Ointments (e.g., Betamethasone, Clobetasol, Hydrocortisone)

• Interaction: Applying other corticosteroid-containing products along with Lomela Cream may increase the risk of skin thinning and other steroid-related side effects.
• Management: Use additional steroid creams only if advised by your doctor.

4. Exfoliating or Acne Products (e.g., Salicylic Acid, Benzoyl Peroxide, Glycolic Acid)

• Interaction: These products may increase skin irritation, redness, dryness, and peeling when used with Lomela Cream.
• Management: Avoid using them on the same area unless your doctor recommends it. If needed, apply them at different times of the day.

5. Products Containing Alcohol or Astringents (e.g., Alcohol-based Toners, Aftershaves)

• Interaction: These products may cause excessive dryness, stinging, or irritation when used with Lomela Cream.
• Management: Choose mild, fragrance-free skincare products while using this medicine.

6. Medicated Soaps and Harsh Cleansers

• Interaction: Harsh cleansers or abrasive soaps may worsen skin irritation caused by Lomela Cream.
• Management: Use a gentle cleanser and avoid scrubbing the treated area.

7. Photosensitising Medicines (e.g., Doxycycline, Ciprofloxacin, Hydrochlorothiazide)

• Interaction: These medicines may increase your skin's sensitivity to sunlight, raising the risk of sunburn while using Lomela Cream.
• Management: Inform your doctor if you are taking medicines that increase sun sensitivity. Use sunscreen and protective clothing when outdoors.

8. Cosmetic Procedures or Skin Treatments (e.g., Chemical Peels, Laser Therapy, Waxing)

• Interaction: Undergoing cosmetic skin treatments while using Lomela Cream may increase skin irritation or damage.
• Management: Tell your dermatologist about your treatment before any cosmetic procedure. Your doctor may advise temporarily stopping the cream before and after the procedure.

Synopsis

More Information

FAQs About LOMELA CREAM

References

1. KD Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of Medical Pharmacology. Eighth Edition, 2019. Page – 952, 953, 955.

2. Kiran V Godse. Triple combination of hydroquinone, tretinoin and mometasone furoate with glycolic acid peels in melasma. NIH National Library of Medicine, National Centre for Biotechnology. Pubmed Central. [Revised in Jan – March 2009]. [Accessed on 30th July 2026] 

3. Torque pharma. No Scars (Hydroquinone + Tretinoin + Mometasone). [Accessed on 30th July 2026] 

4. Leeford Healthcare. Ultrabrite Cream (Hydroquinone + Tretinoin + Mometasone). [Accessed on 30th July 2026] 

Author Details

Written By Dr. R. Dinesh John Rajkumar - Pharm.D

Reviewed For Accuracy By Dr. Janet. C - Pharm.D

Last updated on 08 Aug 2026 | 03:02 PM(IST)