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Introduction About LIVOLUK FIBRE GRANULES
LIVOLUK FIBRE GRANULES is combination of Ispaghula Husk and Lactulose which belongs to the group of medicines called Laxatives. It is used in adults to manage chronic idiopathic constipation (infrequent, difficult or incomplete defecation) in adults.
LIVOLUK FIBRE GRANULES is not recommended for use if you have intestinal obstruction, faecal impaction, senile mega colon (abnormal dilation of colon), undiagnosed rectal bleeding. Consult your doctor before taking it.
LIVOLUK FIBRE GRANULES should be used with caution in patients with liver, kidney disease and diabetes. LIVOLUK FIBRE GRANULES should be used with caution in pregnant and breastfeeding women. Consult your doctor before taking it.
LIVOLUK FIBRE GRANULES should be used with caution in elderly patients. The most common side effects of using LIVOLUK FIBRE GRANULES are flatulence, intestinal cramps, abdominal distention. Consult your doctor if any of the symptoms worsen.
Uses Of LIVOLUK FIBRE GRANULES
Manage:
- Chronic idiopathic constipation
How LIVOLUK FIBRE GRANULES Works
LIVOLUK FIBRE GRANULES helps in managing constipation where Ispaghula husk contains dietary fibre, which when combined with water forms a gel-like mass that works as a mild laxative (used to manage constipation). It moves down the digestive system and works by increasing their water content and softens the stools and Lactulose is broken down in the intestine into fructose and lactose which is neither digested nor absorbed in the small intestine and helps to pull water out from the body and into the colon. This helps to soften stools.
How to use LIVOLUK FIBRE GRANULES
Take LIVOLUK FIBRE GRANULES as advised by your physician. Disperse the medicine in 150 ml of water. Stir the contents briskly and consume immediately. Drink a glass of water after taking the dispersed liquid. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of LIVOLUK FIBRE GRANULES
Common
- flatulence
- intestinal cramps, abdominal distention
How To Manage Side Effects
Indigestion
Eat smaller and frequent meals. Eat and drink slowly and exercise regularly. If the flatulence does not improve, contact your doctor.
Stomach Pain
Try to have smaller meals but take frequently. Keep a heat pad on your stomach. Do not self-manage and contact your doctor if the stomach pain did not improve.
Warning & Precautions
Pregnancy
Use with CautionLIVOLUK FIBRE GRANULES should be used with caution in pregnant women. Consult your doctor before taking it.
Breastfeeding
Use with CautionLIVOLUK FIBRE GRANULES should be used with caution in breastfeeding women. Consult your doctor before taking it.
Kidney
Use with CautionLIVOLUK FIBRE GRANULES should be used with caution in patients with kidney disease. Consult your doctor before taking LIVOLUK FIBRE GRANULES.
Liver
Use with CautionLIVOLUK FIBRE GRANULES should be used with caution in patients with liver impairment. Consult your doctor before taking LIVOLUK FIBRE GRANULES.
Allergy
ContraindicatedDo not take LIVOLUK FIBRE GRANULES if you are allergic to ispaghula husk, lactulose or any other ingredients of this medicine.
Use In Geriatrics
Use with CautionLIVOLUK FIBRE GRANULES should be used with caution in elderly patients. Consult your doctor before taking it.
Others
LIVOLUK FIBRE GRANULES is not recommended for use if you:
- are on low galactose diet
- have intestinal obstruction
- have faecal impaction
- have colonic atony (lack of muscle strength) such as senile mega colon (abnormal dilation of colon)
- have sudden change in bowel habits persisting for more than 2 weeks
- have undiagnosed rectal bleeding
- are unable to defecate even after the use of laxatives
- have diseases of the oesophagus and stomach
- have difficulty in swallowing or any throat problems
- have phenylketonuria (a genetic disorder)
Before taking LIVOLUK FIBRE GRANULES, inform your doctor if you:
- are scheduled for electrocautery procedure during proctoscopy or colonoscopy
- have diabetes
Interactions
A. Drug-Drug Interactions
Before taking LIVOLUK FIBRE GRANULES, inform your doctor, if you are taking any of the following medicine:
- antacids (used to manage heartburn) Ex. aluminium hydroxide
- antibiotics (medicines used to manage bacterial infections) Ex. amoxicillin, neomycin
- thyroid hormones (medicines used to manage thyroid disorders)
Overdosage:
If you or anyone else accidentally takes too much of LIVOLUK FIBRE GRANULES, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are diarrhea with potential complications such as loss of fluids, hypokalemia (low blood potassium levels) and hypernatremia (low blood sodium levels), nausea, vomiting, abdominal discomfort and flatulence.
Synopsis
| Drug | : | Ispaghula Husk and Lactulose |
| Pharmacological Category | : | Laxatives |
| Therapeutic Indication | : | Chronic idiopathic constipation |
| Dosage Forms | : | Granules |
More Information
- Keep LIVOLUK FIBRE GRANULES out of reach of children
- Store LIVOLUK FIBRE GRANULES below 30°C
FAQs About LIVOLUK FIBRE GRANULES
Q: How often can I take LIVOLUK FIBRE GRANULES?
A: Take LIVOLUK FIBRE GRANULES according to the doctors advice. To be taken orally twice daily with plenty of water or as directed by the Physician. Consult your doctor if your symptoms did not improve.
Q: What side effects are seen with LIVOLUK FIBRE GRANULES?
A: The most common side effects of using LIVOLUK FIBRE GRANULES are flatulence, intestinal cramps, abdominal distention. Consult your doctor if any of the symptoms worsen.
Q: Who should avoid taking LIVOLUK FIBRE GRANULES?
A: LIVOLUK FIBRE GRANULES is not recommended for use if you are on low galactose diet or unable to defecate even after the use of laxatives. It is also not recommended for use if you have intestinal obstruction, faecal impaction, colonic atony (lack of muscle strength) such as senile mega colon (abnormal dilation of colon), sudden change in bowel habits persisting for more than 2 weeks, undiagnosed rectal bleeding, diseases of the oesophagus and stomach, difficulty in swallowing, any throat problems or phenylketonuria (a genetic disorder). Consult your doctor before taking it.
Q: Is LIVOLUK FIBRE GRANULES safe to use in pregnant and breastfeeding women?
A: LIVOLUK FIBRE GRANULES should be used with caution in pregnant and breastfeeding women if there is any need of drug therapy for the management of constipation. Consult your doctor before taking it.
Q: Can LIVOLUK FIBRE GRANULES cause flatulence?
A: Yes, LIVOLUK FIBRE GRANULES cause flatulence which can be managed by eating more high-fibre foods such as fresh fruit, vegetables, cereals and drink plenty of water. Eat and drink slowly and try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for the same.
Q: Can LIVOLUK FIBRE GRANULES be used in diabetic patients?
A: Yes, LIVOLUK FIBRE GRANULES can be used in diabetic patients but with caution because it contains lactulose which contains very small amount of galactose and lactose. Consult your doctor before taking it.
References
1. KD. Tripathi. Drugs for Constipation and Diarrhoea & Prescribing in Pregnancy. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 673, 676, 677, 963.
2. Gabrio Bassotti, Paolo Usai Satta, Massimo Bellini. Chronic Idiopathic Constipation in Adults: A Review on Current Guidelines and Emerging Treatment Options. NIH National Library of Medicine, National Centre for Biotechnology Information. PubMed Central. October 2021. [Accessed on 9th February 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547593/
3. Cheng J, Tennila J, Stenman L, Ibarra A, Kumar M, Gupta KK, Sharma SS, Sen D, Garg S, Penurkar M, Kumar S, Ouwehand AC. Influence of Lactitol and Psyllium on Bowel Function in Constipated Indian Volunteers: A Randomized, Controlled Trial. NIH National Library of Medicine, National Centre for Biotechnology Information. PubMed Central. May 2019. [Accessed on 9th February 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566185/
4. Anam Bashir, Omeed Sizar. Laxatives. NIH National Library of Medicine, National Centre for Biotechnology Information. StatPearls. October 2022. [Accessed on 9th February 2023] https://www.ncbi.nlm.nih.gov/books/NBK537246/
5. Nata N, Suebsiripong S, Satirapoj B, Supasyndh O, Chaiprasert A. Efficacy of Lactulose versus Senna Plus Ispaghula Husk Among Patients with Pre-Dialysis Chronic Kidney Disease and Constipation: A Randomized Controlled Trial. NIH National Library of Medicine, National Centre for Biotechnology Information. PubMed Central. August 2021. [Accessed on 9th February 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357401/
6. Biocon Limited. BULKOSE. (Ispaghula Husk + Lactulose). [Accessed on 9th February 2023] https://www.biocon.com/docs/prescribing_information/ccd/bulkose_pi.pdf
7. Bethesda (MD). Eletriptan. National Institute of Health: National Library of Medicine. Medline Plus. March 2016. [Accessed on 9th February 2023] https://medlineplus.gov/druginfo/meds/a682338.html#
Useful Diagnostic Tests
- Serum potassium
- Serum chloride
- Sigmoidoscopy
- Colonoscopy
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