Livodox Tablet 10'S

Introduction About LIVODOX TABLET

LIVODOX TABLET contains Metadoxine, which belongs to a group of medicines called Alcohol Deterrents. LIVODOX TABLET is used in the management of alcohol intoxication, which occurs as a disturbance in behaviour/mental function during or after alcohol consumption in affected individuals.

LIVODOX TABLET is also used to manage chronic alcoholism, which occurs due to habitual and prolonged use of alcoholic beverages in affected individuals.

LIVODOX TABLET is not recommended for use by patients allergic to Metadoxine.

Before taking LIVODOX TABLET, inform your doctor if you suffer from Parkinson's disease (a brain disorder that causes unintended or uncontrollable movements) and/or have kidney problems or liver problems (such as alcoholic liver damage).

LIVODOX TABLET is not recommended for use during pregnancy unless it is clearly necessary. It is also not recommended for use in breastfeeding women as it reduces the synthesis of prolactin (the hormone responsible for producing milk during pregnancy and after birth).

The medicine is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years or older) after consulting the doctor.

The most common side effects of taking LIVODOX TABLET are diarrhea, skin rash, numbness, and/or drowsiness. Consult your doctor if any of these symptoms worsen.

Uses Of LIVODOX TABLET

• Aids in alcohol intoxication
• To manage chronic alcoholism

How LIVODOX TABLET Works

LIVODOX TABLET works by increasing alcohol elimination from blood and tissues, which results in reduced absorption of alcohol by the liver, thus aiding in alcohol intoxication and reducing liver damage in affected individuals.

How to use LIVODOX TABLET

Take LIVODOX TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Side Effects Of LIVODOX TABLET

How To Manage Side Effects

Diarrhea

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptoms worsen.

Warning & Precautions

Pregnancy

Monitoring required

LIVODOX TABLET is generally not recommended for use during pregnancy unless it is clearly necessary. Consult your doctor before taking the medicine.

Breastfeeding

Contraindicated

LIVODOX TABLET is not recommended for use in breastfeeding women as it reduces the synthesis of prolactin (the hormone responsible for producing milk during pregnancy and after birth). Consult your doctor before taking the medicine.

Driving and Using Machines

Use with Caution

LIVODOX TABLET is unlikely to affect your ability to drive or operate any machines. Consult your doctor before taking the medicine.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking LIVODOX TABLET since the medicine is intended to be used for alcohol intoxication.

Kidney

Use with Caution

LIVODOX TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking LIVODOX TABLET.

Liver

Use with Caution

LIVODOX TABLET should be used with caution in patients with liver problems such as alcoholic liver damage. Consult your doctor before taking LIVODOX TABLET.

Allergy

Contraindicated

Do not take LIVODOX TABLET if you are allergic to Metadoxine, and/or any other ingredients of this medicine.

Use In Pediatrics

Contraindicated

LIVODOX TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before administering the medicine to the child.

Use In Geriatrics

Use with Caution

LIVODOX TABLET should be used with caution in elderly patients (aged 65 years or older). Consult your doctor before taking LIVODOX TABLET.

Interactions

A. Drug-Drug Interactions:

• levodopa (used to manage Parkinson’s disease)

Overdosage:

If you or anyone else accidentally takes too much of LIVODOX TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.

Synopsis

More Information

• Keep LIVODOX TABLET out of reach of children
• Store LIVODOX TABLET below 30°C

FAQs About LIVODOX TABLET

Q: What is LIVODOX TABLET used for?

A: LIVODOX TABLET is used to manage alcohol intoxication, which occurs as a disturbance in behaviour/mental function during or after alcohol consumption. It is also used to manage chronic alcoholism, which occurs due to habitual and prolonged use of alcoholic beverages in affected individuals.

Q: What are the common side effects of taking LIVODOX TABLET?

A: The most common side effects of taking LIVODOX TABLET are diarrhea, skin rash, numbness, and/or drowsiness. Consult your doctor if any of these symptoms worsen.

Q: How does LIVODOX TABLET work?

A: LIVODOX TABLET works by increasing alcohol elimination from blood and tissues, which results in reduced absorption of alcohol by the liver, thus aiding in alcohol intoxication and reducing liver damage in affected individuals.

Q: How should LIVODOX TABLET be taken?

A: Take LIVODOX TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Q: Can LIVODOX TABLET be used for pregnant and breastfeeding women?

A: No, LIVODOX TABLET is generally not recommended for use during pregnancy unless it is clearly necessary. It is also not recommended for use in breastfeeding women as it reduces the synthesis of prolactin (the hormone responsible for producing milk during pregnancy and after birth). Consult your doctor before taking the medicine.

References

1. Randi Fredricks. Diet and Substance related disorders. Healing and Wholeness: Complementary and Alternative Therapies for Mental Health. Edition :2008. Page – 288.

2. G Addolorato, C Ancona, E Capristo, G Gasbarrini. Metadoxine in the treatment of acute and chronic alcoholism: a review. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. December 2003. [Accessed on 14th February 2024] https://pubmed.ncbi.nlm.nih.gov/14611722/

3. Yi-Min Mao, Min-de Zeng, You-Ming Li, Bing-Yuan Wang, Jia Shang, Rui-Hua Shi, Ji-Yong Liu, Lun-Gen Lu, Ai-Ping Cao. Capsule Metadoxine in the treatment of alcoholic liver disease: a randomized, double-blind, placebo-controlled, multicenter study. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. March 2009.  [Accessed on 14th February 2024] https://pubmed.ncbi.nlm.nih.gov/19335986/

4. Fátima Higuera-de la Tijera, Alfredo I Servín-Caamaño, Aurora E Serralde-Zúñiga, Javier Cruz-Herrera, Eduardo Pérez-Torres, Juan M Abdo-Francis, Francisco Salas-Gordillo, José L Pérez-Hernández. Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis.  NIH National Library of Medicine. National Center for Biotechnology Information. PubMed Central. April 2015. [Accessed on 14th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408471/

5. Robert joseph miela, Wieslaw jerzy cubala, Katarzyna jakuszkowiak-wojten, Dariusz wojciech mazurkiewicz.  Pharmacotherapy of Alcohol Use disorder: A Review of Current Literature.  ResearchGate. November 2018. [Accessed on 14th February 2024] https://www.researchgate.net/publication/330281803_Pharmacotherapy_of_Alcohol_Use_disorder_A_Review_of_Current_Literature

6. Icon Life Sciences. LIVODOX. [Accessed on 14th February 2024] https://iconlifesciences.in/products.php

7. Icon Life Sciences. LIVODOX. [Accessed on 14th February 2024] https://iconlifesciences.in/products.php

8. Laboratori Baldacci Spa. Italian Medicines Agency (AIFA). [Revised in June 2016] [Accessed on 14th February 2024] https://farmaci.agenziafarmaco.gov.it/bancadatifarmaci/farmaco?farmaco=025316

Useful Diagnostic Tests

• Alcohol(Serum)
• Liver Function Test (LFT)
• Alkaline Phosphatase, Serum
• Bilirubin Direct, Serum
• Bilirubin Total, Serum
• Proteins, Serum
• Sgot/Ast
• Sgpt/Alt
• Complete Blood Count (CBC)/ Hemogram

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 17 Feb 2024 | 06:01 PM(IST)