Lipikind F Tablet 10'S

Introduction About LIPIKIND F TABLET

Lipikind F Tablet is a combination medicine formulated with Atorvastatin (10 mg) and Fenofibrate (160 mg) to help manage high cholesterol and triglyceride levels in adults. It is commonly prescribed to individuals who have mixed dyslipidemia or hyperlipidemia, conditions where the body has excess levels of unhealthy fats. By targeting both cholesterol and triglycerides, Lipikind F Tablet supports improved lipid balance and helps maintain cardiovascular wellness when combined with a healthy lifestyle.

This tablet works through a dual mechanism: Atorvastatin reduces the body’s production of cholesterol by inhibiting the enzyme HMG-CoA reductase, while Fenofibrate enhances the breakdown and clearance of triglycerides from the bloodstream. Together, they help reduce bad cholesterol (LDL and VLDL), raise good cholesterol (HDL), and promote better heart and blood vessel health. Lipikind F Tablet is ideally suited for patients with elevated lipid levels that are not sufficiently managed through diet and exercise alone, or for those at increased cardiovascular risk due to existing health conditions such as diabetes or obesity.

Lipikind F Tablet should be taken once daily after meals with a glass of water, preferably at the same time each day to ensure consistent therapeutic effects. Patients should avoid consuming grapefruit juice and alcohol, as these may interfere with the medicine’s function or increase side effects. Routine lipid profile and liver function tests are recommended to monitor progress and ensure safe use. The tablet should not be crushed or chewed. Missing a dose should be handled by taking it soon after remembering, unless it’s near the next scheduled dose.

It is not recommended during pregnancy or breastfeeding, as both Atorvastatin and Fenofibrate may cause harm to the baby. Common side effects include headache, muscle pain, abdominal discomfort, or mild weakness. In case of severe or unexplained muscle pain, dark urine, or persistent fatigue, medical attention should be sought immediately. Always use this medicine under medical guidance and alongside dietary changes, regular exercise, and lifestyle modifications for best results in maintaining long-term heart and lipid health.

Uses Of LIPIKIND F TABLET

• Reduces bad cholesterol (LDL) and triglycerides
• Increases good cholesterol (HDL)
• Reduces the risk of cardiovascular complications like heart attacks and strokes

Benefits of LIPIKIND F TABLET

Lipikind F Tablet for Cholesterol Control

Lipikind F Tablet helps support healthy cholesterol balance by lowering the levels of bad cholesterol (LDL and VLDL) and triglycerides while increasing good cholesterol (HDL) in the body. It combines two active ingredients Atorvastatin and Fenofibrate that work together to manage lipid levels more effectively. By improving cholesterol balance, this medicine helps keep arteries clear and reduces the buildup of fatty deposits in blood vessels. Following a low-fat diet, regular exercise, and avoiding excess alcohol can enhance the tablet’s cholesterol-lowering benefits.

Lipikind F Tablet for Heart Health

Lipikind F Tablet plays an important role in maintaining overall heart health by promoting better blood circulation and reducing the risk of plaque formation in arteries. By controlling cholesterol and triglyceride levels, it helps lower strain on the heart and supports long-term cardiovascular well-being. Regular use, as prescribed by your doctor, along with a heart-healthy diet and lifestyle changes, can help improve heart function and prevent future heart complications. Always combine the medicine with regular health check-ups to monitor your heart’s condition effectively.

How LIPIKIND F TABLET Works

Mechanism of Action of Lipikind F Tablet

Lipikind F Tablet combines two active ingredients Atorvastatin and Fenofibrate that work together to help manage cholesterol and triglyceride levels in the blood.

Atorvastatin belongs to a group of medicines called HMG-CoA reductase inhibitors (statins). It works by blocking an enzyme in the liver responsible for producing cholesterol, leading to reduced levels of low-density lipoprotein (LDL or “bad” cholesterol) and triglycerides, while increasing high-density lipoprotein (HDL or “good” cholesterol).                                                                                  

Fenofibrate belongs to the class of fibrate derivatives and acts by activating the enzyme lipoprotein lipase, which helps break down triglyceride-rich particles in the blood. It also improves the removal of LDL and enhances HDL formation.              

Together, these actions help reduce fatty deposits in the blood vessels, support smoother blood flow, and contribute to better cardiovascular health.          

How to use LIPIKIND F TABLET

How to Take Lipikind F Tablet

• Take Lipikind F Tablet exactly as directed by your healthcare provider.
• Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.
• It is usually recommended to take the tablet after meals to enhance absorption and reduce stomach discomfort.
• Try to take it at the same time every day to maintain steady levels of the medicine in your body.
• Avoid consuming grapefruit or grapefruit juice while on this medicine, as it may interfere with its metabolism.
• Do not change the dose or stop the medicine without consulting your doctor.
• If you miss a dose, take it as soon as you remember   skip it if it’s close to your next scheduled dose.
• Always follow your doctor’s advice regarding diet and exercise for better results while using Lipikind F Tablet.

What if I forgot to take LIPIKIND F TABLET

• If you forget to take a dose of Lipikind F Tablet, take it as soon as you remember.
• If it’s almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule.
• Do not take two doses at the same time to make up for the missed dose, as it may increase the chance of side effects.
• Try to take the tablet at the same time each day to maintain a steady level of the medicine in your body.
• Setting a daily reminder or alarm can help you stay consistent with your dosage.
• If you miss doses frequently, talk to your doctor for advice on maintaining proper dosage timing.

Overdose

Taking more than the prescribed dose of this medicine may lead to symptoms such as intense muscle pain, unusual weakness, nausea, liver discomfort, or stomach-related distress. If an overdose is suspected, it is important to seek prompt medical assistance or contact the nearest poison control centre without delay. Keeping the medicine strip or a note of the amount taken can help healthcare professionals provide the right support and guidance during the emergency.

Side Effects Of LIPIKIND F TABLET

Common side effects of Lipikind F tablet:

• Muscle pain or weakness
• Headache
• Abdominal discomfort
• elevated liver enzymes

When to Seek Medical Attention?

Stop taking Lipikind F tablet and contact your doctor if you experience any of the following side effects:

• severe allergic skin reactions (such as skin rash, itching, skin redness with blisters or peeling of the skin, swelling in the mouth, which may be associated with high fever and joint pains)
• unexplained muscle pain or weakness, especially if accompanied by fever, weakness or reddish-brown urine
• severe stomach pain due to inflammation of the pancreas
• signs of blood clots in the body (such as chest pain, shortness of breath, pain, redness and swelling in the legs)

How To Manage Side Effects

Headache

• Stay Hydrated: Drink plenty of water throughout the day. Dehydration is one of the most common causes of headaches. You can also consume coconut water or herbal teas to restore electrolytes.
• Apply a Cold or Warm Compress: Use a cold compress on your forehead for tension headaches or a warm compress on the back of your neck to relax tight muscles.
• Rest in a Quiet, Dark Room: Reduce light and noise exposure. Lie down in a calm, dark environment to help your mind and body relax.
• Practice Deep Breathing or Meditation: Stress often triggers headaches. Deep breathing, yoga, or mindfulness meditation can help calm the nervous system and relieve tension.
• Limit Screen Time: Take short breaks every 20–30 minutes if you work on computers or mobile devices. Adjust screen brightness to avoid eye strain.
• Massage Pressure Points: Gently massage the temples, neck, and shoulder muscles to increase blood flow and reduce tightness.
• Maintain Regular Sleep: Get 7–8 hours of quality sleep every night. Poor sleep can trigger frequent headaches.
• Caffeine in Moderation: A small cup of tea or coffee may relieve headaches for some people, but excessive caffeine can have the opposite effect so use it sparingly.
• Aromatherapy:  Essential oils like peppermint or lavender, when applied to the temples or inhaled, can provide mild relaxation and ease discomfort.
• Eat Balanced Meals: Avoid skipping meals, as low blood sugar can trigger headaches. Include complex carbs, proteins, and fruits in your diet.

Stomach Discomfort

• Stay Hydrated: Drink plenty of water throughout the day to aid digestion and prevent bloating. Warm water or herbal teas such as ginger, peppermint, or chamomile can soothe the stomach and ease discomfort.
• Eat Light and Bland Foods: Opt for small, frequent meals instead of heavy portions. Choose easily digestible foods like boiled rice, bananas, applesauce, or toast to reduce strain on the digestive system.
• Avoid Trigger Foods: Stay away from fried, spicy, or fatty foods, as well as caffeine, alcohol, and carbonated beverages, which may worsen discomfort.
• Use a Warm Compress: Placing a warm towel or heating pad over your abdomen for 15–20 minutes can help relax abdominal muscles and reduce cramping or bloating.
• Take Gentle Walks: A short walk after meals helps improve digestion and prevents gas build-up. Avoid lying down immediately after eating to minimize acid reflux or indigestion.
• Practice Mindful Eating: Eat slowly, chew your food thoroughly, and avoid overeating. This reduces air swallowing and supports smoother digestion.
• Try Probiotic-Rich Foods: Including yogurt or fermented foods like buttermilk and kefir in your diet may help maintain healthy gut bacteria and improve digestion.
• Manage Stress: Stress can worsen abdominal discomfort. Practicing deep breathing, meditation, or light yoga may help calm the digestive system.
• Rest Adequately: Allow your body to rest and recover. Fatigue or irregular sleep can disrupt digestion and increase stomach-related issues.
• Consult a Healthcare Professional if Persistent: If abdominal discomfort continues for more than a few days or is accompanied by severe pain, nausea, or changes in bowel habits, seek medical guidance.

Warning & Precautions

Pregnancy

Contraindicated

Studies suggest that the components of Lipikind F Tablet (Atorvastatin and Fenofibrate) may cause harm to an unborn baby. It is advised not to use this medicine during pregnancy. Always consult your gynaecologist for safer alternatives.

Breastfeeding

Contraindicated

Studies suggest that the components of Lipikind F Tablet (Atorvastatin and Fenofibrate) may cause harm to an unborn baby. It is advised not to use this medicine during pregnancy. Always consult your gynaecologist for safer alternatives.

Driving and Using Machines

Use with Caution

Studies suggest that the components of Lipikind F Tablet (Atorvastatin and Fenofibrate) may cause harm to an unborn baby. It is advised not to use this medicine during pregnancy. Always consult your gynaecologist for safer alternatives.

Alcohol

Consult your doctor

Alcohol intake may with the action of Lipikind F Tablet and increase the risk of liver-related side effects. It is best to avoid alcohol and follow your doctor’s advice. 

Kidney

Consult your doctor

This medicine is not suitable for individuals with moderate to severe kidney issues. Those with mild kidney conditions should take it under close medical supervision with dose adjustments if needed.

Liver

Consult your doctor

This medicine is not suitable for individuals with moderate to severe kidney issues. Those with mild kidney conditions should take it under close medical supervision with dose adjustments if needed.

Allergy

Contraindicated

Do not take this medicine if you are allergic to Atorvastatin, Fenofibrate, or any other ingredient present in the formulation.

Lungs

Use with Caution

Patients with existing lung or respiratory issues should use this medicine carefully and under medical supervision. 

Use In Pediatrics

Contraindicated

Lipikind F Tablet is not suitable for children and adolescents below 18 years of age. Consult a paediatrician for appropriate alternatives.

Use In Geriatrics

Use with Caution

Elderly patients (aged 70 years or above) may be more sensitive to this medicine’s effects. Regular monitoring and medical supervision are advised during use.

Other Warnings for LIPIKIND F TABLET

Before taking Lipikind F tablet, inform your doctor if you:

• have diabetes (type I or type II)
• are obese
• have high blood pressure
• have blood problems
• have a previous history of stroke or bleeding in the brain
• have underactive thyroid
• have repeated or unexplainable muscle cramps or pain
• have a family history of muscular disorder
• previously had any muscle problems while taking similar types of lipid-lowering medicines

Who should not take LIPIKIND F TABLET

Lipikind F tablet is not recommended for use if you:

• have inflammation of the pancreas

Safety Advice

• Hydration: Drink enough water daily to protect kidney health.
• Diet: Follow a low-fat, heart-healthy diet while using this medicine.
• Exercise: Combine regular physical activity for better cholesterol control.
• Monitoring: Regular lipid and liver function tests are recommended.
• Avoid Grapefruit: Grapefruit juice may increase side effects risk.
• Medication Disclosure: Inform your doctor about all other medicines you take.
• Surgery: Tell your doctor you’re using Lipikind F before any surgery or dental work.

Diet and Lifestyle Advice

• Follow a heart-healthy diet: Include more fruits, vegetables, whole grains, nuts, and seeds. Choose lean proteins like fish and skinless poultry instead of red meat.
• Limit saturated and trans fats: Avoid fried foods, processed snacks, and bakery items high in unhealthy fats. Use olive or sunflower oil in moderation.
• Reduce salt and sugar intake: Too much salt may raise blood pressure, while added sugars can worsen cholesterol imbalance.
• Stay physically active: Engage in at least 30 minutes of moderate exercise, such as brisk walking, swimming, or cycling, most days of the week.
• Maintain a healthy weight: Even small reductions in weight can improve cholesterol and heart health.
• Avoid alcohol and smoking: Alcohol can strain the liver and alter cholesterol levels; smoking increases the risk of heart disease.
• Stay hydrated: Drink enough water daily to support kidney function and help eliminate toxins.
• Regular health check-ups: Monitor lipid levels and liver function periodically as advised by your doctor.

1. Lipikind F Tablet vs Atorsave F Tablet

2. Lipikind F Tablet vs Tonact TG Tablet

Drug - Drug interaction

1. Interaction with Anticoagulants (e.g., Warfarin)

Interaction: Atorvastatin and Fenofibrate may enhance the effect of blood-thinning medicines like Warfarin, leading to a higher risk of bleeding.
Management: Regular monitoring of blood clotting parameters (like INR) is advised. Report any signs of easy bruising, nosebleeds, or prolonged bleeding to your doctor immediately.

2. Interaction with Antibiotics (e.g., Erythromycin, Clarithromycin)

Interaction: These antibiotics inhibit the liver enzyme (CYP3A4) responsible for metabolizing Atorvastatin. This can increase Atorvastatin levels in the blood, raising the risk of muscle pain or damage.
Management: Avoid combining these antibiotics with Lipikind F Tablet unless prescribed. If co-administration is unavoidable, your doctor may temporarily adjust the dose or monitor muscle health closely.

3. Interaction with Antifungal Medicines (e.g., Ketoconazole, Itraconazole)

Interaction: These antifungal agents slow down the breakdown of Atorvastatin in the body, which can lead to an increased risk of side effects like muscle weakness or liver strain.
Management: Inform your doctor if you are taking antifungal medication. Dose adjustment or an alternative cholesterol-lowering option may be recommended.

4. Interaction with Immunosuppressants (e.g., Cyclosporine)

Interaction: Cyclosporine can significantly increase the blood levels of both Atorvastatin and Fenofibrate, heightening the risk of muscle toxicity or liver enzyme elevation.
Management: Avoid concurrent use unless strictly supervised by a doctor. Regular liver and muscle enzyme monitoring is essential if used together.

5. Interaction with Antidiabetic Medicines (e.g., Pioglitazone, Rosiglitazone)

Interaction: Both Atorvastatin and Fenofibrate may alter blood sugar control when used with antidiabetic agents. This can cause fluctuations in glucose levels.
Management: Diabetic patients should monitor their blood sugar more frequently and inform their healthcare provider if readings become irregular.

6. Interaction with Contraceptive Pills (e.g., Ethinylestradiol, Levonorgestrel)

Interaction: Atorvastatin may influence how the liver processes certain hormonal contraceptives, possibly altering their effectiveness or causing mild liver stress.
Management: Women using oral contraceptives should consult their doctor before starting Lipikind F Tablet to ensure continued protection and safe usage.

7. Interaction with Niacin (Vitamin B3 Supplements)

Interaction: Combining Niacin with Lipikind F can increase the risk of muscle-related side effects such as pain or weakness.
Management: Avoid using high-dose niacin supplements without consulting your doctor. If prescribed together, regular monitoring for muscle symptoms is important.

8. Interaction with Antiepileptic Medicines (e.g., Phenytoin, Carbamazepine)

Interaction: These medicines may increase the metabolism of Atorvastatin, reducing its cholesterol-lowering effectiveness.
Management: Your doctor may recommend lipid profile monitoring and adjust the dose accordingly.

9. Interaction with Fusidic Acid (Antibiotic)

Interaction: Concomitant use may cause serious muscle damage (rhabdomyolysis).
Management: Do not take Fusidic acid and Lipikind F Tablet together. If antibiotic therapy is required, your doctor may pause Lipikind F temporarily.

Drug - Food interaction

1. Interaction with Grapefruit or Grapefruit Juice

Interaction: Grapefruit contains compounds that block the liver enzyme (CYP3A4) responsible for breaking down Atorvastatin. This can increase Atorvastatin levels in the blood, leading to a higher risk of muscle pain or liver-related side effects.
Management: Avoid grapefruit or its juice while taking Lipikind F Tablet. Opt for other fruits like oranges or apples to stay safe.

2. Interaction with High-Fat or Fried Foods

Interaction: Excessive intake of saturated or fried foods can counteract the cholesterol-lowering benefits of Lipikind F. It may also increase the strain on the liver and reduce overall treatment effectiveness.
Management: Follow a balanced, low-fat diet with more fruits, vegetables, and whole grains. Limit intake of fried or processed foods during therapy.

3. Interaction with Caffeine (Tea, Coffee, or Energy Drinks)

Interaction: Caffeine may not directly react with Lipikind F, but excessive intake can elevate heart rate and blood pressure, which may interfere with cardiovascular health goals.
Management: Moderate caffeine intake is generally safe. Stick to 1–2 cups of coffee or tea per day unless your doctor advises otherwise.

4. Interaction with Fiber-Rich Foods or Supplements (e.g., Psyllium Husk)

Interaction: Very high fiber intake, especially close to medication time, may reduce absorption of Atorvastatin and Fenofibrate, lowering their effectiveness.
Management: Take fiber supplements or high-fiber meals a few hours apart from Lipikind F Tablet to ensure proper absorption.

5. Interaction with Antioxidant-Rich Supplements (e.g., Vitamin E, C, Beta-Carotene)

Interaction: Some studies suggest that large doses of antioxidant supplements may reduce the cholesterol-lowering benefits of statins.
Management: Avoid high-dose antioxidant supplements unless prescribed. A natural intake through diet (fruits and vegetables) is safe and beneficial.

6. Interaction with Dairy Products

Interaction: Dairy products like milk and cheese do not directly interact with Lipikind F, but high-fat dairy can reduce lipid control effectiveness if consumed excessively.
Management: Prefer low-fat or skimmed dairy options to maintain balanced cholesterol levels.

7. Interaction with Green Leafy Vegetables (Vitamin K-Rich Foods)

Interaction: While these foods are healthy, those taking Lipikind F along with blood thinners like Warfarin should maintain consistent Vitamin K intake to prevent clotting changes.
Management: Do not drastically change your intake of green leafy vegetables; keep it consistent each week.

Synopsis

More Information

FAQs About LIPIKIND F TABLET

References

1. KD. Tripathi. Hypolipidemic Drugs and Plasma Expanders. Essentials of medical pharmacology. Seventh edition. Page - 637 & 639.

2. Gursharan Sidhu; Jayson Tripp. Fenofibrate. StatPearls [Internet]. NIH. National Library of Medicine. National Center for Biotechnology Information. [Revised in 13th March 2023]. [Accessed on 27th October 2025]. 

3. Shinichi Oikawa, Shizuya Yamashita, Noriaki Nakaya, Jun Sasaki, Suminori Kono. Efficacy and Safety of Long-term Coadministration of Fenofibrate and Ezetimibe in Patients with Combined Hyperlipidemia: Results of the EFECTL Study. NIH. National Library of Medicine. National Center for Biotechnology Information. [Revised 1st January 2017]. [Accessed on 27th October 2025]. 

4. Upjohn UK Limited. Electronic Medicines Compendium (EMC). [Revised in October 2024] [Accessed on 27th October 2025].

5. Sun Pharmaceutical Industries Europe B.V. Electronic Medicines Compendium (EMC). [Revised in October 2024] [Accessed on 27th October 2025]. 

Useful Diagnostic Tests

• Cardiac Risk Profile
• Lipid Profile

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS

Last updated on 31 Oct 2025 | 12:15 PM(IST)